Search

Your search keyword '"SUTER, ANDY"' showing total 4 results
Start Over Author "SUTER, ANDY" Publication Type Electronic Resources
4 results on '"SUTER, ANDY"'

1. New perspectives on saw palmetto (Serenoa repens) : a medico historical/analytical comparison of preparations derived from it and a clinical pilot trial in patients with benign prostatic hyperplasia and sexual dysfunctions

Author

Suter, Andy

Subjects
615.321
Abstract

Saw palmetto berries (Serenoa repens) are used today for treatment of symptoms of benign prostatic hyperplasia (BPH) which is an age dependent disease leading to lower urinary tract symptoms (LUTS) and impacts negatively sexual functions. I carried out the first clinical pilot trial to assess if a saw palmetto treatment in patients with BPH and concomitant sexual dysfunctions (SDys) is effective and safe in both groups of symptoms. After 8 weeks of treatment with 320mg saw palmetto extract daily, BPH symptoms measured with the International Prostate Symptom Score IPSS were reduced from 14.4 ± 4.7 to 6.9 ± 5.2 (p<0.0001). At the same time SDys measured with the brief Sexual Function Inventory bSFI improved from 22.4 ± 7.2 to 31.4 ± 9.2 (p<0.0001), and with the Urolife BPH QoL-9 sex questionnaire from 137.3 ± 47.9 to 195.0 ± 56.3 (p<0.0001). The treatment was very well tolerated and accepted by the patients. Another subject of this thesis was to examine the quality of commercial preparations from eight countries which contained saw palmetto and are sold as treatments for BPH symptoms. For each of the 46 analysed products the amount of the main active constituents, the fatty acids was determined using gas chromatography. The quantity of fatty acids per daily dosage varied widely between the products and also the composition of the samples was very heterogeneous. A medico-historical investigation how saw palmetto was introduced firstly into U.S. American medicine and how the plant became popular as a treatment in Germany was the last aspect of the thesis. The eclectic physicians pioneered in using this plant in the United States supported by homeopathic doctors and pharmacists. In Germany, mainly the homeopaths favoured the use of saw palmetto and were the trailblazers making it a popular treatment for BPH symptoms. In conclusion, this thesis shows comprehensively how saw palmetto made its way into medical practice in the United States and Germany, that preparations on the markets containing saw palmetto differ widely in their content of the main active constituents, the fatty acids, and thus higher quality demands from regulatory authorities are warranted, and in a pilot trial it could be shown that saw palmetto is not only an effective and safe treatment for BPH symptoms but also for concomitant SDys.

Published
2012

2. Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study

Author

Widrig, Reto, Suter, Andy, Saller, Reinhard, Melzer, Jörg, Widrig, Reto, Suter, Andy, Saller, Reinhard, and Melzer, Jörg

Abstract

The use of topical preparations for symptom relief is common in osteoarthritis. The effects of ibuprofen (5%) and arnica (50g tincture/100g, DER 1:20), as gel preparations in patients with radiologically confirmed and symptomatically active osteoarthritis of interphalangeal joints of hands, were evaluated in a randomised, double-blind study in 204 patients, to ascertain differences in pain relief and hand function after 21days' treatment. Diagnosis was according to established criteria; primary endpoints were pain intensity and hand function; statistical design was as per current regulatory guidelines for testing topical preparations. There were no differences between the two groups in pain and hand function improvements, or in any secondary end points evaluated. Adverse events were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica. Our results confirm that this preparation of arnica is not inferior to ibuprofen when treating osteoarthritis of hands

Published
2018

3. Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study

Author

Widrig, Reto, Suter, Andy, Saller, Reinhard, Melzer, Jörg, Widrig, Reto, Suter, Andy, Saller, Reinhard, and Melzer, Jörg

Abstract

The use of topical preparations for symptom relief is common in osteoarthritis. The effects of ibuprofen (5%) and arnica (50g tincture/100g, DER 1:20), as gel preparations in patients with radiologically confirmed and symptomatically active osteoarthritis of interphalangeal joints of hands, were evaluated in a randomised, double-blind study in 204 patients, to ascertain differences in pain relief and hand function after 21days' treatment. Diagnosis was according to established criteria; primary endpoints were pain intensity and hand function; statistical design was as per current regulatory guidelines for testing topical preparations. There were no differences between the two groups in pain and hand function improvements, or in any secondary end points evaluated. Adverse events were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica. Our results confirm that this preparation of arnica is not inferior to ibuprofen when treating osteoarthritis of hands

Published
2007

4. Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study

Author

Widrig, Reto, Suter, Andy, Saller, Reinhard, Melzer, Jörg, Widrig, Reto, Suter, Andy, Saller, Reinhard, and Melzer, Jörg

Abstract

The use of topical preparations for symptom relief is common in osteoarthritis. The effects of ibuprofen (5%) and arnica (50g tincture/100g, DER 1:20), as gel preparations in patients with radiologically confirmed and symptomatically active osteoarthritis of interphalangeal joints of hands, were evaluated in a randomised, double-blind study in 204 patients, to ascertain differences in pain relief and hand function after 21days' treatment. Diagnosis was according to established criteria; primary endpoints were pain intensity and hand function; statistical design was as per current regulatory guidelines for testing topical preparations. There were no differences between the two groups in pain and hand function improvements, or in any secondary end points evaluated. Adverse events were reported by six patients (6.1%) on ibuprofen and by five patients (4.8%) on arnica. Our results confirm that this preparation of arnica is not inferior to ibuprofen when treating osteoarthritis of hands

Catalog

Books, media, physical & digital resources
See catalog results