Search

Your search keyword '"Prudlo J"' showing total 6 results
Start Over Author "Prudlo J" Publication Type Electronic Resources
6 results on '"Prudlo J"'

1. Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning Dementia Praecox Revisited

Author

Koutsouleris, N, Pantelis, C, Velakoulis, D, McGuire, P, Dwyer, DB, Urquijo-Castro, M-F, Paul, R, Sen, D, Popovic, D, Oeztuerk, O, Kambeitz, J, Salokangas, RKR, Hietala, J, Bertolino, A, Brambilla, P, Upthegrove, R, Wood, SJ, Lencer, R, Borgwardt, S, Maj, C, Nothen, M, Degenhardt, F, Polyakova, M, Mueller, K, Villringer, A, Danek, A, Fassbender, K, Fliessbach, K, Jahn, H, Kornhuber, J, Landwehrmeyer, B, Anderl-Straub, S, Prudlo, J, Synofzik, M, Wiltfang, J, Riedl, L, Diehl-Schmid, J, Otto, M, Meisenzahl, E, Falkai, P, Schroeter, ML, Koutsouleris, N, Pantelis, C, Velakoulis, D, McGuire, P, Dwyer, DB, Urquijo-Castro, M-F, Paul, R, Sen, D, Popovic, D, Oeztuerk, O, Kambeitz, J, Salokangas, RKR, Hietala, J, Bertolino, A, Brambilla, P, Upthegrove, R, Wood, SJ, Lencer, R, Borgwardt, S, Maj, C, Nothen, M, Degenhardt, F, Polyakova, M, Mueller, K, Villringer, A, Danek, A, Fassbender, K, Fliessbach, K, Jahn, H, Kornhuber, J, Landwehrmeyer, B, Anderl-Straub, S, Prudlo, J, Synofzik, M, Wiltfang, J, Riedl, L, Diehl-Schmid, J, Otto, M, Meisenzahl, E, Falkai, P, and Schroeter, ML

Abstract

IMPORTANCE: The behavioral and cognitive symptoms of severe psychotic disorders overlap with those seen in dementia. However, shared brain alterations remain disputed, and their relevance for patients in at-risk disease stages has not been explored so far. OBJECTIVE: To use machine learning to compare the expression of structural magnetic resonance imaging (MRI) patterns of behavioral-variant frontotemporal dementia (bvFTD), Alzheimer disease (AD), and schizophrenia; estimate predictability in patients with bvFTD and schizophrenia based on sociodemographic, clinical, and biological data; and examine prognostic value, genetic underpinnings, and progression in patients with clinical high-risk (CHR) states for psychosis or recent-onset depression (ROD). DESIGN, SETTING, AND PARTICIPANTS: This study included 1870 individuals from 5 cohorts, including (1) patients with bvFTD (n = 108), established AD (n = 44), mild cognitive impairment or early-stage AD (n = 96), schizophrenia (n = 157), or major depression (n = 102) to derive and compare diagnostic patterns and (2) patients with CHR (n = 160) or ROD (n = 161) to test patterns' prognostic relevance and progression. Healthy individuals (n = 1042) were used for age-related and cohort-related data calibration. Data were collected from January 1996 to July 2019 and analyzed between April 2020 and April 2022. MAIN OUTCOMES AND MEASURES: Case assignments based on diagnostic patterns; sociodemographic, clinical, and biological data; 2-year functional outcomes and genetic separability of patients with CHR and ROD with high vs low pattern expression; and pattern progression from baseline to follow-up MRI scans in patients with nonrecovery vs preserved recovery. RESULTS: Of 1870 included patients, 902 (48.2%) were female, and the mean (SD) age was 38.0 (19.3) years. The bvFTD pattern comprising prefrontal, insular, and limbic volume reductions was more expressed in patients with schizophrenia (65 of 157 [41.2%]) and major depressi

Published
2022

2. Characterization of disease-specific covariance patterns of neurodegeneration in FTLD-variants

Author

Hammes, J., Bischof, G., Anderl-Straub, S., Barthel, H., Beer, A. J., Danek, A., Eickhoff, S., Fassbender, K., Fliessbach, K., Landwehrmeyer, B., Lauer, M., Ludolph, A. C., Prudlo, J., Schroeter, M. L., Sabri, O., Schmidt-Diehl, J., Schneider, A., Semler, E., Wiltfang, J., Drzezga, A., Otto, M., van Eimeren, T., Hammes, J., Bischof, G., Anderl-Straub, S., Barthel, H., Beer, A. J., Danek, A., Eickhoff, S., Fassbender, K., Fliessbach, K., Landwehrmeyer, B., Lauer, M., Ludolph, A. C., Prudlo, J., Schroeter, M. L., Sabri, O., Schmidt-Diehl, J., Schneider, A., Semler, E., Wiltfang, J., Drzezga, A., Otto, M., and van Eimeren, T.

Published
2018

3. Characterization of disease-specific covariance patterns of neurodegeneration in FTLD-variants

Author

Hammes, J., Bischof, G., Anderl-Straub, S., Barthel, H., Beer, A. J., Danek, A., Eickhoff, S., Fassbender, K., Fliessbach, K., Landwehrmeyer, B., Lauer, M., Ludolph, A. C., Prudlo, J., Schroeter, M. L., Sabri, O., Schmidt-Diehl, J., Schneider, A., Semler, E., Wiltfang, J., Drzezga, A., Otto, M., van Eimeren, T., Hammes, J., Bischof, G., Anderl-Straub, S., Barthel, H., Beer, A. J., Danek, A., Eickhoff, S., Fassbender, K., Fliessbach, K., Landwehrmeyer, B., Lauer, M., Ludolph, A. C., Prudlo, J., Schroeter, M. L., Sabri, O., Schmidt-Diehl, J., Schneider, A., Semler, E., Wiltfang, J., Drzezga, A., Otto, M., and van Eimeren, T.

Published
2018

4. Multivariate diagnostic approaches in Frontotemporal lobar degeneration - Data from the german FTLDc

Author

Straub, S., Schroeter, M. L., Diehl-Schmid, J., Danek, A., von Arnim, C., Bertram, L., Einsiedler, B., Fassbender, K., Feneberg, E., Fliessbach, K., Foerstl, H., Huppertz, H-J, Jahn, H., Jessen, F., Kasper, E., Kassubek, J., Kestler, H. A., Kornhuber, J., Kubisch, C., Landwehrmeyer, B., Lauer, M., Lausser, L., Lill, C. M., Ludolph, A., Maler, M., Muche, R., Pinkhardt, E., Prudlo, J., Riedl, L., Schneider, A., Schomburg, R., Teipel, S., Uttner, I., Volk, A. E., Otto, M., Straub, S., Schroeter, M. L., Diehl-Schmid, J., Danek, A., von Arnim, C., Bertram, L., Einsiedler, B., Fassbender, K., Feneberg, E., Fliessbach, K., Foerstl, H., Huppertz, H-J, Jahn, H., Jessen, F., Kasper, E., Kassubek, J., Kestler, H. A., Kornhuber, J., Kubisch, C., Landwehrmeyer, B., Lauer, M., Lausser, L., Lill, C. M., Ludolph, A., Maler, M., Muche, R., Pinkhardt, E., Prudlo, J., Riedl, L., Schneider, A., Schomburg, R., Teipel, S., Uttner, I., Volk, A. E., and Otto, M.

Published
2016

5. Multivariate diagnostic approaches in Frontotemporal lobar degeneration - Data from the german FTLDc

Author

Straub, S., Schroeter, M. L., Diehl-Schmid, J., Danek, A., von Arnim, C., Bertram, L., Einsiedler, B., Fassbender, K., Feneberg, E., Fliessbach, K., Foerstl, H., Huppertz, H-J, Jahn, H., Jessen, F., Kasper, E., Kassubek, J., Kestler, H. A., Kornhuber, J., Kubisch, C., Landwehrmeyer, B., Lauer, M., Lausser, L., Lill, C. M., Ludolph, A., Maler, M., Muche, R., Pinkhardt, E., Prudlo, J., Riedl, L., Schneider, A., Schomburg, R., Teipel, S., Uttner, I., Volk, A. E., Otto, M., Straub, S., Schroeter, M. L., Diehl-Schmid, J., Danek, A., von Arnim, C., Bertram, L., Einsiedler, B., Fassbender, K., Feneberg, E., Fliessbach, K., Foerstl, H., Huppertz, H-J, Jahn, H., Jessen, F., Kasper, E., Kassubek, J., Kestler, H. A., Kornhuber, J., Kubisch, C., Landwehrmeyer, B., Lauer, M., Lausser, L., Lill, C. M., Ludolph, A., Maler, M., Muche, R., Pinkhardt, E., Prudlo, J., Riedl, L., Schneider, A., Schomburg, R., Teipel, S., Uttner, I., Volk, A. E., and Otto, M.

Published
2016

6. Tullio-Phänomen bei knöcherner Dehiszenz des oberen Bogenganges

Author

Stotz, C, Geisthoff, UW, Prudlo, J, Verse, T, Stotz, C, Geisthoff, UW, Prudlo, J, and Verse, T

Abstract

Einleitung: Seltene Differentialdiagnosen bei Schwindel sind besonders dann wichtig, wenn sie eine therapeutische, wenn nicht gar chirurgische Konsequenz haben. Richtungsweisend für die Diagnose der Dehiszenz des oberen Bogenganges ist Drehschwindel bei Lärmexposition.Methoden: Wir beschreiben einen aktuellen Fall inklusive Videodokumentation und führten eine Literaturrecherche durch.Ergebnisse: Unter Lärmexposition z.B. im Sägewerk, war es bei einem Patienten zu rezidivierenden Schwindelattacken und Stürzen mit Frakturen gekommen. Bei der Untersuchung ließ sich unter Tonexposition links ein rotatorischer Nystagmus dokumentieren. Computertomographisch fand sich eine knöcherne Dehiszenz des oberen Bogenganges links. Therapeutische Möglichkeit ist die operative Deckung der Dehiszenz des betroffenen Bogenganges.Schlussfolgerungen: Bei einem Tullio-Phänomen ist die knöcherne Dehiszenz des oberen Bogenganges als Differentialdiagnose zu berücksichtigen und ggfs. computertomographisch auszuschließen.

Published
2005

Catalog

Books, media, physical & digital resources
See catalog results