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25 results on '"Porcelli, T A"'

1. Predictive molecular pathology in metastatic thyroid cancer: the role of RET fusions

Author

Nacchio, M, Pisapia, P, Pepe, F, Russo, G, Vigliar, E, Porcelli, T, Luongo, C, Iaccarino, A, Pagni, F, Salvatore, D, Troncone, G, Malapelle, U, Bellevicine, C, Nacchio M., Pisapia P., Pepe F., Russo G., Vigliar E., Porcelli T., Luongo C., Iaccarino A., Pagni F., Salvatore D., Troncone G., Malapelle U., Bellevicine C., Nacchio, M, Pisapia, P, Pepe, F, Russo, G, Vigliar, E, Porcelli, T, Luongo, C, Iaccarino, A, Pagni, F, Salvatore, D, Troncone, G, Malapelle, U, Bellevicine, C, Nacchio M., Pisapia P., Pepe F., Russo G., Vigliar E., Porcelli T., Luongo C., Iaccarino A., Pagni F., Salvatore D., Troncone G., Malapelle U., and Bellevicine C.

Abstract

Background: Rearranged during transfection (RET) gene fusions are detected in 10–20% of thyroid cancer patients. Recently, RET fusion-positive metastatic thyroid cancers have attracted much attention owing to the FDA approval of two highly selective anti-RET tyrosine kinase inhibitors, namely, selpercatinib, and pralsetinib. Areas covered: This review summarizes the available evidence on the biological and predictive role of RET gene fusions in thyroid carcinoma patients and the latest screening assays currently used to detect these genomic alterations in histological and cytological specimens. Expert opinion: Management of advanced thyroid carcinoma has significantly evolved over the last decade thanks to the approval of three multikinase inhibitors, i.e. sorafenib, lenvatinib, cabozantinib, and of two selective RET-tyrosine inhibitors, i.e. selpercatinib and pralsetinib. In this setting, the detection of RET-fusions in advanced thyroid cancer specimens through the use of next-generation sequencing has become a commonly used strategy in clinical practice to select the best treatment options.

Published
2022

2. Treatment of Acromegalic Osteopathy in Real-life Clinical Practice: The BAAC (Bone Active Drugs in Acromegaly) Study

Author

Mazziotti, G, Battista, C, Maffezzoni, F, Chiloiro, Sabrina, Ferrante, E, Prencipe, N, Grasso, L, Gatto, F, Olivetti, R, Arosio, M, Barale, M, Bianchi, Antonio, Cellini, M, Chiodini, I, De Marinis Grasso, Laura, Del Sindaco, G, Di Somma, C, Ferlin, A, Ghigo, E, Giampietro, Antonella, Grottoli, S, Lavezzi, E, Mantovani, G, Morenghi, E, Pivonello, R, Porcelli, T, Procopio, M, Pugliese, F, Scillitani, A, Lania, Ag., Chiloiro S (ORCID:0000-0001-9241-2392), Bianchi A, De Marinis Laura (ORCID:0000-0001-9916-0669), Giampietro A, Mazziotti, G, Battista, C, Maffezzoni, F, Chiloiro, Sabrina, Ferrante, E, Prencipe, N, Grasso, L, Gatto, F, Olivetti, R, Arosio, M, Barale, M, Bianchi, Antonio, Cellini, M, Chiodini, I, De Marinis Grasso, Laura, Del Sindaco, G, Di Somma, C, Ferlin, A, Ghigo, E, Giampietro, Antonella, Grottoli, S, Lavezzi, E, Mantovani, G, Morenghi, E, Pivonello, R, Porcelli, T, Procopio, M, Pugliese, F, Scillitani, A, Lania, Ag., Chiloiro S (ORCID:0000-0001-9241-2392), Bianchi A, De Marinis Laura (ORCID:0000-0001-9916-0669), and Giampietro A

Abstract

Background: Vertebral fractures (VFs) are a frequent complication of acromegaly, but no studies have been so far published on effectiveness of antiosteoporotic drugs in this clinical setting. Objective: To evaluate whether in real-life clinical practice bone active drugs may reduce the risk of VFs in patients with active or controlled acromegaly. Study design: Retrospective, longitudinal study including 9 tertiary care endocrine units. Patients and methods: Two hundred and forty-eight patients with acromegaly (104 males; mean age 56.00 ± 13.60 years) were evaluated for prevalent and incident VFs by quantitative morphometric approach. Bone active agents were used in 52 patients (20.97%) and the median period of follow-up was 48 months (range 12-132). Results: During the follow-up, 65 patients (26.21%) developed incident VFs in relationship with pre-existing VFs (odds ratio [OR] 3.75; P < .001), duration of active acromegaly (OR 1.01; P = .04), active acromegaly at the study entry (OR 2.48; P = .007), and treated hypoadrenalism (OR 2.50; P = .005). In the entire population, treatment with bone active drugs did not have a significant effect on incident VFs (P = .82). However, in a sensitive analysis restricted to patients with active acromegaly at study entry (111 cases), treatment with bone active drugs was associated with a lower risk of incident VFs (OR 0.11; P = .004), independently of prevalent VFs (OR 7.65; P < .001) and treated hypoadrenalism (OR 3.86; P = .007). Conclusions: Bone active drugs may prevent VFs in patients with active acromegaly.

Published
2020

3. Massini liturgico e aneddotico

Author

Turchetta, G, Gambaro, E, Rosa, G, Cenati, G, Novelli, M, Sergio, G, Petruzzi, MS, Barenghi, M, Ghidinelli, S, Gallarini, L, Raccis, G, Daino, L, Fiori, U, Porcelli, T, Caputo, F, Sullam, S, Strazzeri, G, Galbiati, W, Dubini, P, Pallotta, V, Falcetto, B, Cosat, P, Terreni, A, Cesana, R, Parise, S, Spinazzola, V, Turchetta, G, Gambaro, E, Rosa, G, Cenati, G, Novelli, M, Sergio, G, Petruzzi, MS, Barenghi, M, Ghidinelli, S, Gallarini, L, Raccis, G, Daino, L, Fiori, U, Porcelli, T, Caputo, F, Sullam, S, Strazzeri, G, Galbiati, W, Dubini, P, Pallotta, V, Falcetto, B, Cosat, P, Terreni, A, Cesana, R, Parise, S, and Spinazzola, V

Abstract

Drammaturgo, narratore, affabulatore, Massini affronta temi grandi e piccoli della realtà contemporanea ritagliando storie e teatralizzandole: sia nella lunga saga della famiglia Lehman, sia negli episodi esemplari raccontati in pochi minuti, lo strumento decisivo è sempre la modulazione recitante della voce.

Published
2019

4. Massini liturgico e aneddotico

Author

Turchetta, G, Gambaro, E, Rosa, G, Cenati, G, Novelli, M, Sergio, G, Petruzzi, MS, Barenghi, M, Ghidinelli, S, Gallarini, L, Raccis, G, Daino, L, Fiori, U, Porcelli, T, Caputo, F, Sullam, S, Strazzeri, G, Galbiati, W, Dubini, P, Pallotta, V, Falcetto, B, Cosat, P, Terreni, A, Cesana, R, Parise, S, Spinazzola, V, Turchetta, G, Gambaro, E, Rosa, G, Cenati, G, Novelli, M, Sergio, G, Petruzzi, MS, Barenghi, M, Ghidinelli, S, Gallarini, L, Raccis, G, Daino, L, Fiori, U, Porcelli, T, Caputo, F, Sullam, S, Strazzeri, G, Galbiati, W, Dubini, P, Pallotta, V, Falcetto, B, Cosat, P, Terreni, A, Cesana, R, Parise, S, and Spinazzola, V

Abstract

Drammaturgo, narratore, affabulatore, Massini affronta temi grandi e piccoli della realtà contemporanea ritagliando storie e teatralizzandole: sia nella lunga saga della famiglia Lehman, sia negli episodi esemplari raccontati in pochi minuti, lo strumento decisivo è sempre la modulazione recitante della voce.

Published
2019

5. Oltre il terreno della memoria

Author

Spinazzola, V, Sergio, G, Novelli, M, Turchetta, G, Pischedda, B, Fiori, U, Porcelli, T, Richelmi, C, Daino, L, Giovannetti, P, Barenghi, M, Petruzzi, MS, Cenati, G, Gallarini, L, Palieri, MS, Dubini, P, Galbiati, W, Strazzeri, G, Attanasio, P, Pallotta, V, Maccarelli, L, Costa, P, Terreni, A, Cesana, M, Sullam, S, Parise, S, Spinazzola, V, Sergio, G, Novelli, M, Turchetta, G, Pischedda, B, Fiori, U, Porcelli, T, Richelmi, C, Daino, L, Giovannetti, P, Barenghi, M, Petruzzi, MS, Cenati, G, Gallarini, L, Palieri, MS, Dubini, P, Galbiati, W, Strazzeri, G, Attanasio, P, Pallotta, V, Maccarelli, L, Costa, P, Terreni, A, Cesana, M, Sullam, S, and Parise, S

Abstract

Negli anni, Milano ha rappresentato il luogo delle opportunità per più di una generazione: dalla “leggenda privata” dei Mari, col nonno Gino trasferitosi da Spinazzola nelle Murge, all’educazione milanese di Rollo, originario di Lecce, fino agli immigrati raccontati da Giuseppe Lupo in Gli anni del nostro incanto. Un romanzo, un’autobiografia in senso proprio e un’autobiografia leggendaria raccontano ciascuno a proprio modo il mito della Milano del secondo Novecento. Un mito fatto di contraddizioni, ma dalle molte chiavi interpretative.

Published
2018

6. Bone safety of dual-release hydrocortisone in patients with hypopituitarism.

Author

Frara, S, Chiloiro, Sabrina, Porcelli, T, Giampietro, Antonella, Mazziotti, G, De Marinis Grasso, Laura, Giustina, A., Chiloiro S (ORCID:0000-0001-9241-2392), Giampietro A, De Marinis Laura (ORCID:0000-0001-9916-0669), Frara, S, Chiloiro, Sabrina, Porcelli, T, Giampietro, Antonella, Mazziotti, G, De Marinis Grasso, Laura, Giustina, A., Chiloiro S (ORCID:0000-0001-9241-2392), Giampietro A, and De Marinis Laura (ORCID:0000-0001-9916-0669)

Published
2018

7. Plurihormonal ACTH-GH Pituitary Adenoma: Case Report and Systematic Literature Review

Author

Roca, E., Mattogno, Pier Paolo, Porcelli, T., Poliani, L., Belotti, F., Schreiber, A., Maffezzoni, F., Fontanella, Marco Maria, Doglietto, Francesco, Mattogno P. P., Fontanella M. M., Doglietto F. (ORCID:0000-0002-7438-0734), Roca, E., Mattogno, Pier Paolo, Porcelli, T., Poliani, L., Belotti, F., Schreiber, A., Maffezzoni, F., Fontanella, Marco Maria, Doglietto, Francesco, Mattogno P. P., Fontanella M. M., and Doglietto F. (ORCID:0000-0002-7438-0734)

Abstract

Background: Plurihormonal adenomas (PHAs) represent 10%–15% of all functioning pituitary adenomas. The most frequent hormonal associations are with prolactin and growth hormone (GH). Here we describe a rare case of functional adrenocorticotropic hormone (ACTH) and GH microadenoma and report our findings from a systematic literature review of PHA. Methods: We searched PubMed using the terms “plurihormonal pituitary adenoma,” “ACTH GH pituitary adenoma,” and “acromegaly AND Cushing's disease”. In the 17 articles that were selected for literature review, only 20% (4/20) of patients presented with clinical signs of both diseases. Histologically, 19 were pituitary adenomas composed of two distinct cell populations, while only in 1 case was there evidence of a single cell producing both ACTH and GH. In the case reported here, a 60-year-old woman was incidentally diagnosed with a pituitary microadenoma. Endocrine assessment documented increased levels of insulin-like growth factor 1 and GH; ACTH and cortisol values were within normal ranges. Echocardiography documented ventricular hypertrophy. Because of clinical and biochemical evidence of acromegaly, surgery was recommended. Postoperatively, hormonal replacement therapy was started because of adrenal insufficiency. Her antihypertensive therapy was discontinued due to evidence of normal blood pressure values. Histological examination revealed an ACTH-GH PHA with 2 distinct populations of secreting cells. At 3-year follow-up, the patient showed stable clinical remission and was no longer receiving hormonal replacement therapy. Conclusions: This is an additional case to the 20 previously reported cases of ACTH-GH PHA. Awareness of this relatively rare entity is clinically relevant. The cytogenesis of ACTH-GH PHA remains a matter of debate, and several hypotheses have been postulated.

Published
2018

8. L’autoritratto di una generazione

Author

Turchetta, G, Pischedda, B, Spianzzola, V, Cosa, P, Novelli, M, Cenati, G, Sergio, G, Falcetto, B, Porcelli, T, Speciale, A, Rosa, G, Gallarini, L, Gambaro E, Interdonato, P, Palieri, MS, Barenghi, M, Giovannetti, P, Fiori, U, Dubini, P, Galbiati, W, Zapparoli, M, Moretti, D, Maccarelli, L, Attanasio, P, Pallotta, W, Bona, F, Daino, L, Petruzzi, MS, Terreni, A, Mussinelli, C, Sullam, S, Cesana, R, Parise, F, Spinazzola, V, BARENGHI, MARIO LUIGI, Turchetta, G, Pischedda, B, Spianzzola, V, Cosa, P, Novelli, M, Cenati, G, Sergio, G, Falcetto, B, Porcelli, T, Speciale, A, Rosa, G, Gallarini, L, Gambaro E, Interdonato, P, Palieri, MS, Barenghi, M, Giovannetti, P, Fiori, U, Dubini, P, Galbiati, W, Zapparoli, M, Moretti, D, Maccarelli, L, Attanasio, P, Pallotta, W, Bona, F, Daino, L, Petruzzi, MS, Terreni, A, Mussinelli, C, Sullam, S, Cesana, R, Parise, F, Spinazzola, V, and BARENGHI, MARIO LUIGI

Abstract

Né vera e propria narrazione romanzesca, né autofiction, "La scuola cattolica" di Edoardo Albinati costituisce per molti aspetti il libro di un'intera generazione; ma questo non solo per le accurate ricostruzioni storico-sociali e per il tentativo di ritrarre il processo di formazione di un'intera mentalità. È infatti soprattutto nella sua prolissità e dispersione che il testo sembra rispecchiare le difficoltà degli ex baby-boomers nel trasmettere ai propri figli il senso e l'eredità di una esperienza.

Published
2017

9. Il metodo e il fine di Saviano

Author

Spinazzola, V, Cangemi, L, Scarabelli, R, Peresson, G, Speciale, A, Sullam, S, Giovannetti, P, Terreni, A, Costa, P, Papi, G, Porcelli, T, Gallarini, L, Novelli, M, Pischedda, B, Barenghi, M, Turchetta, G, Rosa, G, Sergio, G, Coyaud, S, Rovida, C, Petruzzi, MS, Clerici, L, Fiori, U, Daino, L, Dubini, P, Galbiati, W, Cenati, G, Lepri, L, Cardone, R, Ghidinelli, S, Zapparoli, M, Palieri, MS, BARENGHI, MARIO LUIGI, Spinazzola, V, Cangemi, L, Scarabelli, R, Peresson, G, Speciale, A, Sullam, S, Giovannetti, P, Terreni, A, Costa, P, Papi, G, Porcelli, T, Gallarini, L, Novelli, M, Pischedda, B, Barenghi, M, Turchetta, G, Rosa, G, Sergio, G, Coyaud, S, Rovida, C, Petruzzi, MS, Clerici, L, Fiori, U, Daino, L, Dubini, P, Galbiati, W, Cenati, G, Lepri, L, Cardone, R, Ghidinelli, S, Zapparoli, M, Palieri, MS, and BARENGHI, MARIO LUIGI

Abstract

Le polemiche che hanno accompagnato l’uscita negli USA di Zero Zero Zero hanno riaperto la questione dell’attendibilità della scrittura di Roberto Saviano. Ma nel romanzo, al di là delle accuse di plagio e di «disonestà», ciò che più delude è il rapporto tra il protagonista e il territorio narrato. Costretto a ricorrere a intermediari per raccontare una vicenda che si snoda su scala planetaria, infatti, il narratore si affida a una ricerca dell’effetto esasperata e inefficace.

Published
2016

10. Il sonnambulismo wuminghiano

Author

Giovannetti, P, Spinazzola, V, Gambaro, F, Daino, L, Bona, F, Sergio, G, Turchetta, G, Gallarini, L, Cenati, G, Barbisan, I, Rosa, G, Barenghi, M, Novelli, M, Palieri, MS, Ghidinelli, S, Raffaelli, L, Fiori, U, Porcelli, T, Petruzzi, S, Costa, P, Dubini, P, Maccarelli, L, Moretti, D, Terreni, A, Coyaud, S, Cerutti, L, Galbiati, W, Speciale, A, Cadioli, A, Attanasio, P, BARENGHI, MARIO LUIGI, Giovannetti, P, Spinazzola, V, Gambaro, F, Daino, L, Bona, F, Sergio, G, Turchetta, G, Gallarini, L, Cenati, G, Barbisan, I, Rosa, G, Barenghi, M, Novelli, M, Palieri, MS, Ghidinelli, S, Raffaelli, L, Fiori, U, Porcelli, T, Petruzzi, S, Costa, P, Dubini, P, Maccarelli, L, Moretti, D, Terreni, A, Coyaud, S, Cerutti, L, Galbiati, W, Speciale, A, Cadioli, A, Attanasio, P, and BARENGHI, MARIO LUIGI

Abstract

Con l’ultimo libro i Wu Ming proseguono nel solco della sperimentazione di genere: L’armata dei sonnambuli è un romanzo storico a più livelli di lettura in cui l’accurata ricostruzione del contesto parigino negli anni del Terrore rivoluzionario si intreccia a vicende dai connotati fantastici. Il confronto, all’interno della storia, tra realtà e percezione degli eventi offre lo spunto per riflettere su due tematiche centrali nel dibattito sull’attualità: la contaminazione tra politica e spettacolo e le tecniche di persuasione collettiva.

Published
2015

11. Vertebral fractures in patients with acromegaly: a 3-year prospective study

Author

Mazziotti, G, Bianchi, Antonio, Porcelli, T, Mormando, Marilda, Maffezzoni, F, Cristiano, A, Giampietro, Antonella, De Marinis Grasso, Laura, Giustina, A., De Marinis, Laura (ORCID:0000-0001-9916-0669), Mazziotti, G, Bianchi, Antonio, Porcelli, T, Mormando, Marilda, Maffezzoni, F, Cristiano, A, Giampietro, Antonella, De Marinis Grasso, Laura, Giustina, A., and De Marinis, Laura (ORCID:0000-0001-9916-0669)

Abstract

Cross-sectional studies showed an elevated prevalence of vertebral fractures in acromegaly. However, no data are available on incident vertebral fractures in this clinical setting.

Published
2013

12. Gli occhiali di Cipputi

Author

Marigonda, E, Falcetto, B, Cenati, G, Bona, F, Novelli, M, Pischedda, B, Barenghi, M, Rosa, G, Spinazzola, V, Rollo, A, Cadioli, A, Giovannetti, P, Richelmi, C, Palieri, MS, Coyaud, S, Ghidinelli, S, Fiori, U, Interdonato, P, Petruzzi, MS, Gambaro, M, Dubini, P, Moretti, D, Terreni, A, Cerutti, L, Stabile, S, Guerzoni, G, Lepri, L, Nani, G, Carnero, R, Porcelli, T, Attanasio, P, Peresson, G, Ginevra, M, Salis, S, Raviola, E, Gallo, G, Massinelli, C, BARENGHI, MARIO LUIGI, Marigonda, E, Falcetto, B, Cenati, G, Bona, F, Novelli, M, Pischedda, B, Barenghi, M, Rosa, G, Spinazzola, V, Rollo, A, Cadioli, A, Giovannetti, P, Richelmi, C, Palieri, MS, Coyaud, S, Ghidinelli, S, Fiori, U, Interdonato, P, Petruzzi, MS, Gambaro, M, Dubini, P, Moretti, D, Terreni, A, Cerutti, L, Stabile, S, Guerzoni, G, Lepri, L, Nani, G, Carnero, R, Porcelli, T, Attanasio, P, Peresson, G, Ginevra, M, Salis, S, Raviola, E, Gallo, G, Massinelli, C, and BARENGHI, MARIO LUIGI

Abstract

Profilo del famoso personaggio di Altan. – "Marx è morto". "E noi qui a fare la classe operaia, come dei pirla". Cipputi è uno di quelli che tengono in piedi la baracca; sempre al lavoro in tuta e guanti, sempre alle prese con qualche macchinario. Nella vita dell'operaio dal naso prominente creato da Altan non c'è tempo per la nostalgia, il sentimentalismo, la rassegnazione. Ma c'è spazio per la coscienza di classe e per un'ironia impassibilmente lucida che, da dietro le lenti spesse del nascondono lo sguardo, si scaglia in un colpo solo contro i meccanismi del potere, i privilegi dei padroni, l'immaturità delle forze politiche progressive.

Published
2008

13. Transverse beam spin asymmetries in forward-angle elastic electron-proton scattering

Author

Physics, Armstrong, D. S., Arvieux, J., Asaturyan, R., Averett, T., Bailey, S. L., Batigne, G., Beck, D. H., Beise, E. J., Benesch, J., Bimbot, L., Birchall, J., Biselli, A., Bosted, P., Boukobza, E., Breuer, H., Carlini, R., Carr, Rachel E., Chant, N., Chao, Y. C., Chattopadhyay, S., Clark, R., Covrig, S., Cowley, A., Dale, D., Davis, C., Falk, W., Finn, J. M., Forest, T., Franklin, G., Furget, C., Gaskell, D., Grames, J., Griffioen, K. A., Grimm, K., Guillon, B., Guler, H., Hannelius, L., Hasty, R., Allen, A. H., Horn, T., Johnston, K., Jones, M., Kammel, P., Kazimi, R., King, P. M., Kolarkar, A., Korkmaz, E., Korsch, W., Kox, S., Kuhn, J., Lachniet, J., Lee, L., Lenoble, J., Liatard, E., Liu, J., Loupias, B., Lung, A., Marchand, D., Martin, J. W., McFarlane, K. W., McKee, D. W., McKeown, R. D., Merchez, F., Mkrtchyan, H., Moffit, B., Morlet, M., Nakagawa, I., Nakahara, K., Neveling, R., Ong, S., Page, S., Papavassiliou, V., Pate, S. F., Phillips, S. K., Pitt, M. L., Poelker, M., Porcelli, T. A., Quemener, G., Quinn, B., Ramsay, W. D., Rauf, A. W., Real, J. S., Roche, J., Roos, P., Rutledge, G. A., Secrest, J., Simicevic, N., Smith, G. R., Spayde, D. T., Stepanyan, S., Stutzman, M., Sulkosky, V., Tadevosyan, V., Tieulent, R., de Wiele, J. V., van Oers, W. T. H., Voutier, E., Vulcan, W., Warren, G., Wells, S. P., Williamson, S. E., Wood, S. A., Yan, C., Yun, J., Zeps, V., Physics, Armstrong, D. S., Arvieux, J., Asaturyan, R., Averett, T., Bailey, S. L., Batigne, G., Beck, D. H., Beise, E. J., Benesch, J., Bimbot, L., Birchall, J., Biselli, A., Bosted, P., Boukobza, E., Breuer, H., Carlini, R., Carr, Rachel E., Chant, N., Chao, Y. C., Chattopadhyay, S., Clark, R., Covrig, S., Cowley, A., Dale, D., Davis, C., Falk, W., Finn, J. M., Forest, T., Franklin, G., Furget, C., Gaskell, D., Grames, J., Griffioen, K. A., Grimm, K., Guillon, B., Guler, H., Hannelius, L., Hasty, R., Allen, A. H., Horn, T., Johnston, K., Jones, M., Kammel, P., Kazimi, R., King, P. M., Kolarkar, A., Korkmaz, E., Korsch, W., Kox, S., Kuhn, J., Lachniet, J., Lee, L., Lenoble, J., Liatard, E., Liu, J., Loupias, B., Lung, A., Marchand, D., Martin, J. W., McFarlane, K. W., McKee, D. W., McKeown, R. D., Merchez, F., Mkrtchyan, H., Moffit, B., Morlet, M., Nakagawa, I., Nakahara, K., Neveling, R., Ong, S., Page, S., Papavassiliou, V., Pate, S. F., Phillips, S. K., Pitt, M. L., Poelker, M., Porcelli, T. A., Quemener, G., Quinn, B., Ramsay, W. D., Rauf, A. W., Real, J. S., Roche, J., Roos, P., Rutledge, G. A., Secrest, J., Simicevic, N., Smith, G. R., Spayde, D. T., Stepanyan, S., Stutzman, M., Sulkosky, V., Tadevosyan, V., Tieulent, R., de Wiele, J. V., van Oers, W. T. H., Voutier, E., Vulcan, W., Warren, G., Wells, S. P., Williamson, S. E., Wood, S. A., Yan, C., Yun, J., and Zeps, V.

Abstract

We have measured the beam-normal single-spin asymmetry in elastic scattering of transversely polarized 3 GeV electrons from unpolarized protons at Q(2)=0.15, 0.25 (GeV/c)(2). The results are inconsistent with calculations solely using the elastic nucleon intermediate state and generally agree with calculations with significant inelastic hadronic intermediate state contributions. A(n) provides a direct probe of the imaginary component of the 2 gamma exchange amplitude, the complete description of which is important in the interpretation of data from precision electron-scattering experiments.

Published
2007

14. Measurement of P_{mu}xi in Polarized Muon Decay

Author

TWIST Collaboration, Jamieson, B., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gaponenko, A., Gill, D. R., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Kitching, P., Koetke, D. D., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Mischke, R. E., Musser, J. R., Nozar, M., Olchanski, K., Olin, A., Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., Vasiliev, M. A., TWIST Collaboration, Jamieson, B., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gaponenko, A., Gill, D. R., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Kitching, P., Koetke, D. D., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Mischke, R. E., Musser, J. R., Nozar, M., Olchanski, K., Olin, A., Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., and Vasiliev, M. A.

Abstract

The quantity P_{mu}^{pi}xi, where xi is one of the muon decay parameters and $P_{\mu}^{\pi}$ is the degree of muon polarization in pion decay, has been measured. The value P_{mu}^{pi}xi = 1.0003 +- 0.0006 stat. +- 0.0038 syst. was obtained. This result agrees with previous measurements but is over a factor of two more precise. It also agrees with the Standard Model prediction for P_{mu}^{pi}xi and thus leads to restrictions on left-right symmetric models., Comment: 11 pages, 7 figures, Phys. Rev. D 74, 072007 (2006) Final version

Published
2006
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15. Measurement of P_{mu}xi in Polarized Muon Decay

Author

TWIST Collaboration, Jamieson, B., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gaponenko, A., Gill, D. R., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Kitching, P., Koetke, D. D., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Mischke, R. E., Musser, J. R., Nozar, M., Olchanski, K., Olin, A., Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., Vasiliev, M. A., TWIST Collaboration, Jamieson, B., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gaponenko, A., Gill, D. R., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Kitching, P., Koetke, D. D., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Mischke, R. E., Musser, J. R., Nozar, M., Olchanski, K., Olin, A., Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., and Vasiliev, M. A.

Abstract

The quantity P_{mu}^{pi}xi, where xi is one of the muon decay parameters and $P_{\mu}^{\pi}$ is the degree of muon polarization in pion decay, has been measured. The value P_{mu}^{pi}xi = 1.0003 +- 0.0006 stat. +- 0.0038 syst. was obtained. This result agrees with previous measurements but is over a factor of two more precise. It also agrees with the Standard Model prediction for P_{mu}^{pi}xi and thus leads to restrictions on left-right symmetric models., Comment: 11 pages, 7 figures, Phys. Rev. D 74, 072007 (2006) Final version

Published
2006
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16. Ramsauer-Townsend effect in muonic atom scattering

Author

Mulhauser, Françoise, Adamczak, A., Beer, G. A., Bystritsky, V. M., Filipowicz, M., Fujiwara, M. C., Huber, T. M., Huot, Olivier, Jacot-Guillarmod, R., Kammel, P., Kim, S. K., Knowles, Paul E., Kunselman, A. R., Marshall, G. M., Olin, A., Petitjean, C., Porcelli, T. A., Schaller, Lukas A., Stolupin, V. A., Woźniak, J., Zmeskal, J., Mulhauser, Françoise, Adamczak, A., Beer, G. A., Bystritsky, V. M., Filipowicz, M., Fujiwara, M. C., Huber, T. M., Huot, Olivier, Jacot-Guillarmod, R., Kammel, P., Kim, S. K., Knowles, Paul E., Kunselman, A. R., Marshall, G. M., Olin, A., Petitjean, C., Porcelli, T. A., Schaller, Lukas A., Stolupin, V. A., Woźniak, J., and Zmeskal, J.

Abstract

We present the final results of an experimental study of µd and µt atom scattering in solid hydrogen cooled to 3 K. Strong effects resulting from the Ramsauer-Townsend effect have been observed in the TRIUMF experiment E742 where muons were stopped in thin frozen layers of hydrogen. The measured Ramsauer-Townsend minimum energy for both µd and µt atoms and the minimum cross section are in agreement with theory

Published
2006

17. Measurement of the Muon Decay Parameter delta

Author

TWIST Collaboration, Gaponenko, A., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gill, D. R., Green, P., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Jamieson, B., Kitching, P., Koetke, D. D., Krushinsky, A. A., Lachin, Yu. Yu., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Miasoedov, L. V., Mischke, R. E., Musser, J. R., Nord, P. M., Nozar, M., Olchanski, K., Olin, A., 7, Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Sobratee, F., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., Vasiliev, M. A., Wright, D. H., TWIST Collaboration, Gaponenko, A., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gill, D. R., Green, P., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Jamieson, B., Kitching, P., Koetke, D. D., Krushinsky, A. A., Lachin, Yu. Yu., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Miasoedov, L. V., Mischke, R. E., Musser, J. R., Nord, P. M., Nozar, M., Olchanski, K., Olin, A., 7, Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Sobratee, F., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., Vasiliev, M. A., and Wright, D. H.

Abstract

The muon decay parameter delta has been measured by the TWIST collaboration. We find delta = 0.74964 +- 0.00066(stat.) +- 0.00112(syst.), consistent with the Standard Model value of 3/4. This result implies that the product Pmuxi of the muon polarization in pion decay, Pmu, and the muon decay parameter xi falls within the 90% confidence interval 0.9960 < Pmuxi < xi < 1.0040. It also has implications for left-right-symmetric and other extensions of the Standard Model., Comment: Extended to 5 pages. Referee's comments answered

Published
2004
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18. Measurement of the Muon Decay Parameter delta

Author

TWIST Collaboration, Gaponenko, A., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gill, D. R., Green, P., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Jamieson, B., Kitching, P., Koetke, D. D., Krushinsky, A. A., Lachin, Yu. Yu., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Miasoedov, L. V., Mischke, R. E., Musser, J. R., Nord, P. M., Nozar, M., Olchanski, K., Olin, A., 7, Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Sobratee, F., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., Vasiliev, M. A., Wright, D. H., TWIST Collaboration, Gaponenko, A., Bayes, R., Davydov, Yu. I., Depommier, P., Doornbos, J., Faszer, W., Fujiwara, M. C., Gagliardi, C. A., Gill, D. R., Green, P., Gumplinger, P., Hasinoff, M. D., Henderson, R. S., Hu, J., Jamieson, B., Kitching, P., Koetke, D. D., Krushinsky, A. A., Lachin, Yu. Yu., Macdonald, J. A., MacDonald, R. P., Marshall, G. M., Mathie, E. L., Miasoedov, L. V., Mischke, R. E., Musser, J. R., Nord, P. M., Nozar, M., Olchanski, K., Olin, A., 7, Openshaw, R., Porcelli, T. A., Poutissou, J. -M., Poutissou, R., Quraan, M. A., Rodning, N. L., Selivanov, V., Sheffer, G., Shin, B., Sobratee, F., Stanislaus, T. D. S., Tacik, R., Torokhov, V. D., Tribble, R. E., Vasiliev, M. A., and Wright, D. H.

Abstract

The muon decay parameter delta has been measured by the TWIST collaboration. We find delta = 0.74964 +- 0.00066(stat.) +- 0.00112(syst.), consistent with the Standard Model value of 3/4. This result implies that the product Pmuxi of the muon polarization in pion decay, Pmu, and the muon decay parameter xi falls within the 90% confidence interval 0.9960 < Pmuxi < xi < 1.0040. It also has implications for left-right-symmetric and other extensions of the Standard Model., Comment: Extended to 5 pages. Referee's comments answered

Published
2004
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19. Time-of-Flight Spectroscopy of Muonic Hydrogen Atoms and Molecules

Author

TRIUMF Muonic Hydrogen Collaboration, Fujiwara, M. C., Adamczak, A., Bailey, J. M., Beer, G. A., Beveridge, J. L., Faifman, M. P., Huber, T. M., Kammel, P., Kim, S. K., Knowles, P. E., Kunselman, A. R., Markushin, V. E., Marshall, G. M., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., Zmeskal, J., TRIUMF Muonic Hydrogen Collaboration, Fujiwara, M. C., Adamczak, A., Bailey, J. M., Beer, G. A., Beveridge, J. L., Faifman, M. P., Huber, T. M., Kammel, P., Kim, S. K., Knowles, P. E., Kunselman, A. R., Markushin, V. E., Marshall, G. M., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., and Zmeskal, J.

Abstract

Studies of muonic hydrogen atoms and molecules have been performed traditionally in bulk targets of gas, liquid or solid. At TRIUMF, Canada's meson facility, we have developed a new type of target system using multilayer thin films of solid hydrogen, which provides a beam of muonic hydrogen atoms in vacuum. Using the time-of-flight of the muonic atoms, the energy-dependent information of muonic reactions are obtained in direct manner. We discuss some unique measurements enabled by the new technique, with emphasis on processes relevant to muon catalyzed fusion., Comment: Contribution to Hydrogen Atom II --- Precise Physics with Simple Atomic Systems (Springer, Berlin)

Published
2001

20. Resonant Formation of $d\mu t$ Molecules in Deuterium: An Atomic Beam Measurement of Muon Catalyzed dt Fusion

Author

TRIUMF Munoic Hydrogen Collaboration, Fujiwara, M. C., Adamczak, A., Bailey, J. M., Beer, G. A., Beveridge, J. L., Faifman, M. P., Huber, T. M., Kammel, P., Kim, S. K., Knowles, P. E., Kunselman, A. R., Maier, M., Markushin, V. E., Marshall, G. M., Martoff, C. J., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., Wozniak, J., Zmeskal, J., TRIUMF Munoic Hydrogen Collaboration, Fujiwara, M. C., Adamczak, A., Bailey, J. M., Beer, G. A., Beveridge, J. L., Faifman, M. P., Huber, T. M., Kammel, P., Kim, S. K., Knowles, P. E., Kunselman, A. R., Maier, M., Markushin, V. E., Marshall, G. M., Martoff, C. J., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., Wozniak, J., and Zmeskal, J.

Abstract

Resonant formation of $d\mu t$ molecules in collisions of muonic tritium ($\mu t$) on D$_2$ was investigated using a beam of $\mu t$ atoms, demonstrating a new direct approach in muon catalyzed fusion studies. Strong epithermal resonances in $d\mu t$ formation were directly revealed for the first time. From the time-of-flight analysis of $2036\pm 116$ $dt$ fusion events, a formation rate consistent with $0.73\pm (0.16)_{meas} \pm (0.09)_{model}$ times the theoretical prediction was obtained. For the largest peak at a resonance energy of $0.423 \pm 0.037$ eV, this corresponds to a rate of $(7.1 \pm 1.8) \times 10^9$ s$^{-1}$, more than an order of magnitude larger than those at low energies., Comment: To appear in Phys. Rev. Lett

Published
2000
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21. Using Thin Film Targets for Muonic Atoms and Muon Catalyzed Fusion Studies

Author

TRIUMF Munoic Hydrogen Collaboration, Fujiwara, M. C., Adamczak, A., Bailey, J. M., Beer, G. A., Beveridge, J. L., Faifman, M. P., Huber, T. M., Kammel, P., Kim, S. K., Knowles, P. E., Kunselman, A. R., Markushin, V. E., Marshall, G. M., Martoff, C. J., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., Zmeskal, J., TRIUMF Munoic Hydrogen Collaboration, Fujiwara, M. C., Adamczak, A., Bailey, J. M., Beer, G. A., Beveridge, J. L., Faifman, M. P., Huber, T. M., Kammel, P., Kim, S. K., Knowles, P. E., Kunselman, A. R., Markushin, V. E., Marshall, G. M., Martoff, C. J., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., and Zmeskal, J.

Abstract

Studies of muonic atoms and muon catalyzed fusion have been conventionally done in a bulk target of gas, liquid or solid hydrogen isotopes. The use of thin film targets developed at TRIUMF have notable advantages in tackling some of the most important questions in the field, which could be further exploited at future high intensity muon sources. We review the technique of the thin film method with emphasis on recent results and a future proposal., Comment: Talk given at KEK International Workshop on High Intensity Muon Sources, HIMUS-99

Published
2000

22. Muon catalyzed fusion in 3-K solid deuterium

Author

Huber, Thomas M., Knowles, P.E.; Beer, G. A.; Mason, G. R.; Porcelli, T. A.; Adamczak, A.; Bailey, J. M.; Beveridge, J. L.; Marshall, G. M.; Olin, A.; Fujiwara, M. C.; Jacot-Guillarmod, R.; Mulhauser, F.; Kammel, P.; Zmeskal, J.; Kim, S. K.; Kunselman, A. R.; Martoff, C.J.; Petitjean, C., Huber, Thomas M., and Knowles, P.E.; Beer, G. A.; Mason, G. R.; Porcelli, T. A.; Adamczak, A.; Bailey, J. M.; Beveridge, J. L.; Marshall, G. M.; Olin, A.; Fujiwara, M. C.; Jacot-Guillarmod, R.; Mulhauser, F.; Kammel, P.; Zmeskal, J.; Kim, S. K.; Kunselman, A. R.; Martoff, C.J.; Petitjean, C.

Abstract

The TRIUMF solid-hydrogen-layer target system has been used to study the fusion reaction rates in the solid phase of D2 at a target temperature of 3 K. Products of two distinct branches of the reaction were observed: neutrons by a liquid organic scintillator and protons by a silicon detector located inside the target system.

Published
1997

23. Characterization of Solidified Gas Thin Film Targets via Alpha Particle Energy Loss

Author

MUH collaboration, Fujiwara, M. C., Beer, G. A., Beveridge, J. L., Douglas, J. L., Huber, T. M., Jacot-Guillarmod, R., Kim, S. K., Knowles, P. E., Kunselman, A. R., Maier, M., Marshall, G. M., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., Zmeskal, J., MUH collaboration, Fujiwara, M. C., Beer, G. A., Beveridge, J. L., Douglas, J. L., Huber, T. M., Jacot-Guillarmod, R., Kim, S. K., Knowles, P. E., Kunselman, A. R., Maier, M., Marshall, G. M., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., and Zmeskal, J.

Abstract

A method is reported for measuring the thickness and uniformity of thin films of solidified gas targets. The energy of alpha particles traversing the film is measured and the energy loss is converted to thickness using the stopping power. The uniformity is determined by measuring the thickness at different positions with an array of sources. Monte Carlo simulations have been performed to study the film deposition mechanism. Thickness calibrations for a TRIUMF solid hydrogen target system are presented., Comment: 25 pages, 11 figures (psfig), submitted to Nucl. Intrum. Meth. A

Published
1996
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24. Characterization of Solidified Gas Thin Film Targets via Alpha Particle Energy Loss

Author

MUH collaboration, Fujiwara, M. C., Beer, G. A., Beveridge, J. L., Douglas, J. L., Huber, T. M., Jacot-Guillarmod, R., Kim, S. K., Knowles, P. E., Kunselman, A. R., Maier, M., Marshall, G. M., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., Zmeskal, J., MUH collaboration, Fujiwara, M. C., Beer, G. A., Beveridge, J. L., Douglas, J. L., Huber, T. M., Jacot-Guillarmod, R., Kim, S. K., Knowles, P. E., Kunselman, A. R., Maier, M., Marshall, G. M., Mason, G. R., Mulhauser, F., Olin, A., Petitjean, C., Porcelli, T. A., and Zmeskal, J.

Abstract

A method is reported for measuring the thickness and uniformity of thin films of solidified gas targets. The energy of alpha particles traversing the film is measured and the energy loss is converted to thickness using the stopping power. The uniformity is determined by measuring the thickness at different positions with an array of sources. Monte Carlo simulations have been performed to study the film deposition mechanism. Thickness calibrations for a TRIUMF solid hydrogen target system are presented., Comment: 25 pages, 11 figures (psfig), submitted to Nucl. Intrum. Meth. A

Published
1996
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25. Ramsauer-Townsend effect in muonic atom scattering

Author

Mulhauser, Françoise, Adamczak, A., Beer, G. A., Bystritsky, V. M., Filipowicz, M., Fujiwara, M. C., Huber, T. M., Huot, Olivier, Jacot-Guillarmod, R., Kammel, P., Kim, S. K., Knowles, Paul E., Kunselman, A. R., Marshall, G. M., Olin, A., Petitjean, C., Porcelli, T. A., Schaller, Lukas A., Stolupin, V. A., Woźniak, J., Zmeskal, J., Mulhauser, Françoise, Adamczak, A., Beer, G. A., Bystritsky, V. M., Filipowicz, M., Fujiwara, M. C., Huber, T. M., Huot, Olivier, Jacot-Guillarmod, R., Kammel, P., Kim, S. K., Knowles, Paul E., Kunselman, A. R., Marshall, G. M., Olin, A., Petitjean, C., Porcelli, T. A., Schaller, Lukas A., Stolupin, V. A., Woźniak, J., and Zmeskal, J.

Abstract

We present the final results of an experimental study of µd and µt atom scattering in solid hydrogen cooled to 3 K. Strong effects resulting from the Ramsauer-Townsend effect have been observed in the TRIUMF experiment E742 where muons were stopped in thin frozen layers of hydrogen. The measured Ramsauer-Townsend minimum energy for both µd and µt atoms and the minimum cross section are in agreement with theory

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