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10 results on '"Pfau, S."'

1. Roadmap for the Chemical Industry in Europe towards a Bioeconomy : action plan

Author

Panchaksharam, Y., Kiri, P., Bauen, A., Berg, C. vom, Puente, Á., Chinthapalli, R., Spekreijse, J., Vos, J., Pfau, S., Rübberdt, K., Michels, J., König, L., Panchaksharam, Y., Kiri, P., Bauen, A., Berg, C. vom, Puente, Á., Chinthapalli, R., Spekreijse, J., Vos, J., Pfau, S., Rübberdt, K., Michels, J., and König, L.

Abstract

The RoadToBio project is funded by the EU under the Horizon 2020 research and innovation programme. Its aim is to provide a roadmap for the European chemical industry to exploit potential opportunities offered by the bioeconomy and increase the share of bio-based products. The RoadToBio bio-based chemicals roadmap for the European chemical industry (“RoadtoBio roadmap”) aspires to increase the share of bio-based or renewable feedstock1 to 25% of the total volume of organic chemicals raw materials/feedstock used by the chemical industry in 2030. To meet societal needs the biomass used for bio-based chemicals must meet stringent sustainability criteria including on direct and indirect land use change.

Published
2019

2. Roadmap for the Chemical Industry in Europe towards a Bioeconomy : strategy document

Author

Panchaksharam, Y., Kiri, P., Bauen, A., Berg, C. vom, Puente, Á., Chinthapalli, R., Spekreijse, J., Vos, J., Pfau, S., Rübberdt, K., Michels, J., König, L., Panchaksharam, Y., Kiri, P., Bauen, A., Berg, C. vom, Puente, Á., Chinthapalli, R., Spekreijse, J., Vos, J., Pfau, S., Rübberdt, K., Michels, J., and König, L.

Abstract

The RoadToBio project is funded by the EU under the Horizon 2020 research and innovation programme. It aims to pave the way for the European chemical industry towards a higher bio-based portfolio and competitive success based on the benefits offered by the bioeconomy. The goal of RoadToBio is to create a roadmap for the chemical industry with the aspiration to increase the share of bio-based or renewable feedstock to 25% of total volume of organic chemicals raw materials/feedstock used by the chemical industry in 2030. Societal needs in 2030 need to be considered while aspiring for this target. The biomass used for bio-based chemicals should meet stringent sustainability criteria including on direct and indirect land use change.

Published
2019

8. Hadronic energy resolution of a highly granular scintillator-steel hadron calorimeter using software compensation techniques

Author

CALICE Collaboration, Adloff, C., Blaha, J., Blaising, J. -J., Drancourt, C., Espargilière, A., Gaglione, R., Geffroy, N., Karyotakis, Y., Prast, J., Vouters, G., Francis, K., Repond, J., Smith, J., Xia, L., Baldolemar, E., Li, J., Park, S. T., Sosebee, M., White, A. P., Yu, J., Buanes, T., Eigen, G., Mikami, Y., Watson, N. K., Goto, T., Mavromanolakis, G., Thomson, M. A., Ward, D. R., Yan, W., Benchekroun, D., Hoummada, A., Khoulaki, Y., Benyamna, M., Cârloganu, C., Fehr, F., Gay, P., Manen, S., Royer, L., Blazey, G. C., Dyshkant, A., Lima, J. G. R., Zutshi, V., Hostachy, J. -Y., Morin, L., Cornett, U., David, D., Falley, G., Gadow, K., Göttlicher, P., Günter, C., Hermberg, B., Karstensen, S., Krivan, F., Lucaci-Timoce, A. -I., Lu, S., Lutz, B., Morozov, S., Morgunov, V., Reinecke, M., Sefkow, F., Smirnov, P., Terwort, M., Vargas-Trevino, A., Feege, N., Garutti, E., Marchesini, I., Ramilli, M., Eckert, P., Harion, T., Kaplan, A., Schultz-Coulon, H. -Ch., Shen, W., Stamen, R., Tadday, A., Bilki, B., Norbeck, E., Onel, Y., Wilson, G. W., Kawagoe, K., Dauncey, P. D., Magnan, A. -M., Wing, M., Salvatore, F., Alamillo, E. Calvo, Fouz, M. -C., Puerta-Pelayo, J., Balagura, V., Bobchenko, B., Chadeeva, M., Danilov, M., Epifantsev, A., Markin, O., Mizuk, R., Novikov, E., Rusinov, V., Tarkovsky, E., Kirikova, N., Kozlov, V., Soloviev, Y., Buzhan, P., Dolgoshein, B., Ilyin, A., Kantserov, V., Kaplin, V., Karakash, A., Popova, E., Smirnov, S., Kiesling, C., Pfau, S., Seidel, K., Simon, F., Soldner, C., Szalay, M., Tesar, M., Weuste, L., Bonis, J., Bouquet, B., Callier, S., Cornebise, P., Doublet, Ph., Dulucq, F., Giannelli, M. Faucci, Fleury, J., Li, H., Martin-Chassard, G., Richard, F., de la Taille, Ch., Pöschl, R., Raux, L., Seguin-Moreau, N., Wicek, F., Anduze, M., Boudry, V., Brient, J-C., Jeans, D., de Freitas, P. Mora, Musat, G., Reinhard, M., Ruan, M., Videau, H., Bulanek, B., Zacek, J., Cvach, J., Gallus, P., Havranek, M., Janata, M., Kvasnicka, J., Lednicky, D., Marcisovsky, M., Polak, I., Popule, J., Tomasek, L., Tomasek, M., Ruzicka, P., Sicho, P., Smolik, J., Vrba, V., Zalesak, J., Belhorma, B., Ghazlane, H., Takeshita, T., Uozumi, S., Sauer, J., Weber, S., Zeitnitz, C., CALICE Collaboration, Adloff, C., Blaha, J., Blaising, J. -J., Drancourt, C., Espargilière, A., Gaglione, R., Geffroy, N., Karyotakis, Y., Prast, J., Vouters, G., Francis, K., Repond, J., Smith, J., Xia, L., Baldolemar, E., Li, J., Park, S. T., Sosebee, M., White, A. P., Yu, J., Buanes, T., Eigen, G., Mikami, Y., Watson, N. K., Goto, T., Mavromanolakis, G., Thomson, M. A., Ward, D. R., Yan, W., Benchekroun, D., Hoummada, A., Khoulaki, Y., Benyamna, M., Cârloganu, C., Fehr, F., Gay, P., Manen, S., Royer, L., Blazey, G. C., Dyshkant, A., Lima, J. G. R., Zutshi, V., Hostachy, J. -Y., Morin, L., Cornett, U., David, D., Falley, G., Gadow, K., Göttlicher, P., Günter, C., Hermberg, B., Karstensen, S., Krivan, F., Lucaci-Timoce, A. -I., Lu, S., Lutz, B., Morozov, S., Morgunov, V., Reinecke, M., Sefkow, F., Smirnov, P., Terwort, M., Vargas-Trevino, A., Feege, N., Garutti, E., Marchesini, I., Ramilli, M., Eckert, P., Harion, T., Kaplan, A., Schultz-Coulon, H. -Ch., Shen, W., Stamen, R., Tadday, A., Bilki, B., Norbeck, E., Onel, Y., Wilson, G. W., Kawagoe, K., Dauncey, P. D., Magnan, A. -M., Wing, M., Salvatore, F., Alamillo, E. Calvo, Fouz, M. -C., Puerta-Pelayo, J., Balagura, V., Bobchenko, B., Chadeeva, M., Danilov, M., Epifantsev, A., Markin, O., Mizuk, R., Novikov, E., Rusinov, V., Tarkovsky, E., Kirikova, N., Kozlov, V., Soloviev, Y., Buzhan, P., Dolgoshein, B., Ilyin, A., Kantserov, V., Kaplin, V., Karakash, A., Popova, E., Smirnov, S., Kiesling, C., Pfau, S., Seidel, K., Simon, F., Soldner, C., Szalay, M., Tesar, M., Weuste, L., Bonis, J., Bouquet, B., Callier, S., Cornebise, P., Doublet, Ph., Dulucq, F., Giannelli, M. Faucci, Fleury, J., Li, H., Martin-Chassard, G., Richard, F., de la Taille, Ch., Pöschl, R., Raux, L., Seguin-Moreau, N., Wicek, F., Anduze, M., Boudry, V., Brient, J-C., Jeans, D., de Freitas, P. Mora, Musat, G., Reinhard, M., Ruan, M., Videau, H., Bulanek, B., Zacek, J., Cvach, J., Gallus, P., Havranek, M., Janata, M., Kvasnicka, J., Lednicky, D., Marcisovsky, M., Polak, I., Popule, J., Tomasek, L., Tomasek, M., Ruzicka, P., Sicho, P., Smolik, J., Vrba, V., Zalesak, J., Belhorma, B., Ghazlane, H., Takeshita, T., Uozumi, S., Sauer, J., Weber, S., and Zeitnitz, C.

Abstract

The energy resolution of a highly granular 1 m3 analogue scintillator-steel hadronic calorimeter is studied using charged pions with energies from 10 GeV to 80 GeV at the CERN SPS. The energy resolution for single hadrons is determined to be approximately 58%/sqrt(E/GeV}. This resolution is improved to approximately 45%/sqrt(E/GeV) with software compensation techniques. These techniques take advantage of the event-by-event information about the substructure of hadronic showers which is provided by the imaging capabilities of the calorimeter. The energy reconstruction is improved either with corrections based on the local energy density or by applying a single correction factor to the event energy sum derived from a global measure of the shower energy density. The application of the compensation algorithms to Geant4 simulations yield resolution improvements comparable to those observed for real data., Comment: 26 pages, 14 figures

Published
2012
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9. An inflammatory pathway of IFN-gamma production in coronary atherosclerosis

Author

Ranjbaran, H, Sokol, Si, Gallo, A, Eid, Re, Iakimov, Ao, D'Alessio, Alessio, Kapoor, Jr, Akhtar, S, Howes, Cj, Aslan, M, Pfau, S, Pober, J, Tellides, G., D'Alessio, Alessio (ORCID:0000-0002-3340-2634), Pober, Js, Ranjbaran, H, Sokol, Si, Gallo, A, Eid, Re, Iakimov, Ao, D'Alessio, Alessio, Kapoor, Jr, Akhtar, S, Howes, Cj, Aslan, M, Pfau, S, Pober, J, Tellides, G., D'Alessio, Alessio (ORCID:0000-0002-3340-2634), and Pober, Js

Abstract

Inflammation is associated with the pathogenesis of coronary atherosclerosis, although the mechanisms remain unclear. We investigated whether cytokine secretion by innate immune responses could contribute to the production of proarteriosclerotic Th1-type cytokines in human coronary atherosclerosis. Cytokines were measured by ELISA in the plasma of patients with coronary atherosclerosis undergoing cardiac catheterization. IL-18 was detected in all subjects, whereas a subset of patients demonstrated a coordinated induction of other IFN-gamma-related cytokines. Specifically, elevated plasma levels of IL-12 correlated with that of IFN-gamma and IFN-gamma-inducible chemokines, defining an IFN-gamma axis that was activated independently of IL-6 or C-reactive protein. Systemic inflammation triggered by cardiopulmonary bypass increased plasma levels of the IFN-gamma axis, but not that of IL-18. Activation of the IFN-gamma axis was not associated with acute coronary syndromes, but portended increased morbidity and mortality after 1-year follow-up. IL-12 and IL-18, but not other monokines, elicited secretion of IFN-gamma and IFN-gamma-inducible chemokines in human atherosclerotic coronary arteries maintained in organ culture. T cells were the principal source of IFN-gamma in response to IL-12/IL-18 within the arterial wall. This inflammatory response did not require, but was synergistic with and primed for TCR signals. IL-12/IL-18-stimulated T cells displayed a cytokine-producing, nonproliferating, and noncytolytic phenotype, consistent with previous descriptions of lymphocytes in stable plaques. In contrast to cognate stimuli, IL-12/IL-18-dependent IFN-gamma secretion was prevented by a p38 MAPK inhibitor and not by cyclosporine. In conclusion, circulating IL-12 may provide a mechanistic link between inflammation and Th1-type cytokine production in coronary atherosclerosis.

Published
2007

10. Hadronic energy resolution of a highly granular scintillator-steel hadron calorimeter using software compensation techniques

Author

Laboratoire d'Annecy le Vieux de Physique des Particules (LAPP) ; CNRS - IN2P3 - Université de Savoie, Laboratoire de Physique Corpusculaire [Clermont-Ferrand] (LPC) ; CNRS - IN2P3 - Université Blaise Pascal - Clermont-Ferrand II, Laboratoire de Physique Subatomique et de Cosmologie (LPSC) ; CNRS - IN2P3 - Université Joseph Fourier - Grenoble I - Institut Polytechnique de Grenoble - Grenoble Institute of Technology, Laboratoire de l'Accélérateur Linéaire (LAL) ; CNRS - IN2P3 - Université Paris XI - Paris Sud, Laboratoire Leprince-Ringuet (LLR) ; CNRS - IN2P3 - Polytechnique - X, CALICE, Adloff, C., Blaha, J., Blaising, J. -J., Drancourt, C., Espargilière, A., Gaglione, R., Geffroy, N., Karyotakis, Y., Prast, J., Vouters, G., Francis, K., Repond, J., Smith, J., Xia, L., Baldolemar, E., Li, J., Park, S. T., Sosebee, M., White, A. P., Yu, J., Buanes, T., Eigen, G., Mikami, Y., Watson, N. K., Goto, T., Mavromanolakis, G., Thomson, M. A., Ward, D. R., Yan, W., Benchekroun, D., Hoummada, A., Khoulaki, Y., Benyamna, M., Cârloganu, C., Fehr, F., Gay, P., Manen, S., Royer, L., Blazey, G. C., Dyshkant, A., Lima, J. G. R., Zutshi, V., Hostachy, J.Y., Morin, L., Cornett, U., David, D., Falley, G., Gadow, K., Göttlicher, P., Günter, C., Hermberg, B., Karstensen, S., Krivan, F., Lucaci-Timoce, A. -I., Lu, S., Lutz, B., Morozov, S., Morgunov, V., Reinecke, M., Sefkow, F., Smirnov, P., Terwort, M., Vargas-Trevino, A., Feege, N., Garutti, E., Marchesini, I., Ramilli, M., Eckert, P., Harion, T., Kaplan, A., Schultz-Coulon, H. -Ch., Shen, W., Stamen, R., Tadday, A., Bilki, B., Norbeck, E., Onel, Y., Wilson, G. W., Kawagoe, K., Dauncey, P. D., Magnan, A. -M., Wing, M., Salvatore, F., Alamillo, E. Calvo, Fouz, M. -C., Puerta-Pelayo, J., Balagura, V., Bobchenko, B., Chadeeva, M., Danilov, M., Epifantsev, A., Markin, O., Mizuk, R., Novikov, E., Rusinov, V., Tarkovsky, E., Kirikova, N., Kozlov, V., Soloviev, Y., Buzhan, P., Dolgoshein, B., Ilyin, A., Kantserov, V., Kaplin, V., Karakash, A., Popova, E., Smirnov, S., Kiesling, C., Pfau, S., Seidel, K., Simon, F., Soldner, C., Szalay, M., Tesar, M., Weuste, L., Bonis, J., Bouquet, B., Callier, S., Cornebise, P., Doublet, Ph., Dulucq, F., Giannelli, M. Faucci, Fleury, J., Li, H., Martin-Chassard, G., Richard, F., De La Taille, Ch., Pöschl, R., Raux, L., Seguin-Moreau, N., Wicek, F., Anduze, M., Boudry, V., Brient, J-C., Jeans, D., De Freitas, P. Mora, Musat, G., Reinhard, M., Ruan, M., Videau, H., Bulanek, B., Zacek, J., Cvach, J., Gallus, P., Havranek, M., Janata, M., Kvasnicka, J., Lednicky, D., Marcisovsky, M., Polak, I., Popule, J., Tomasek, L., Tomasek, M., Ruzicka, P., Sicho, P., Smolik, J., Vrba, V., Zalesak, J., Belhorma, B., Ghazlane, H., Takeshita, T., Uozumi, S., Laboratoire d'Annecy le Vieux de Physique des Particules (LAPP) ; CNRS - IN2P3 - Université de Savoie, Laboratoire de Physique Corpusculaire [Clermont-Ferrand] (LPC) ; CNRS - IN2P3 - Université Blaise Pascal - Clermont-Ferrand II, Laboratoire de Physique Subatomique et de Cosmologie (LPSC) ; CNRS - IN2P3 - Université Joseph Fourier - Grenoble I - Institut Polytechnique de Grenoble - Grenoble Institute of Technology, Laboratoire de l'Accélérateur Linéaire (LAL) ; CNRS - IN2P3 - Université Paris XI - Paris Sud, Laboratoire Leprince-Ringuet (LLR) ; CNRS - IN2P3 - Polytechnique - X, CALICE, Adloff, C., Blaha, J., Blaising, J. -J., Drancourt, C., Espargilière, A., Gaglione, R., Geffroy, N., Karyotakis, Y., Prast, J., Vouters, G., Francis, K., Repond, J., Smith, J., Xia, L., Baldolemar, E., Li, J., Park, S. T., Sosebee, M., White, A. P., Yu, J., Buanes, T., Eigen, G., Mikami, Y., Watson, N. K., Goto, T., Mavromanolakis, G., Thomson, M. A., Ward, D. R., Yan, W., Benchekroun, D., Hoummada, A., Khoulaki, Y., Benyamna, M., Cârloganu, C., Fehr, F., Gay, P., Manen, S., Royer, L., Blazey, G. C., Dyshkant, A., Lima, J. G. R., Zutshi, V., Hostachy, J.Y., Morin, L., Cornett, U., David, D., Falley, G., Gadow, K., Göttlicher, P., Günter, C., Hermberg, B., Karstensen, S., Krivan, F., Lucaci-Timoce, A. -I., Lu, S., Lutz, B., Morozov, S., Morgunov, V., Reinecke, M., Sefkow, F., Smirnov, P., Terwort, M., Vargas-Trevino, A., Feege, N., Garutti, E., Marchesini, I., Ramilli, M., Eckert, P., Harion, T., Kaplan, A., Schultz-Coulon, H. -Ch., Shen, W., Stamen, R., Tadday, A., Bilki, B., Norbeck, E., Onel, Y., Wilson, G. W., Kawagoe, K., Dauncey, P. D., Magnan, A. -M., Wing, M., Salvatore, F., Alamillo, E. Calvo, Fouz, M. -C., Puerta-Pelayo, J., Balagura, V., Bobchenko, B., Chadeeva, M., Danilov, M., Epifantsev, A., Markin, O., Mizuk, R., Novikov, E., Rusinov, V., Tarkovsky, E., Kirikova, N., Kozlov, V., Soloviev, Y., Buzhan, P., Dolgoshein, B., Ilyin, A., Kantserov, V., Kaplin, V., Karakash, A., Popova, E., Smirnov, S., Kiesling, C., Pfau, S., Seidel, K., Simon, F., Soldner, C., Szalay, M., Tesar, M., Weuste, L., Bonis, J., Bouquet, B., Callier, S., Cornebise, P., Doublet, Ph., Dulucq, F., Giannelli, M. Faucci, Fleury, J., Li, H., Martin-Chassard, G., Richard, F., De La Taille, Ch., Pöschl, R., Raux, L., Seguin-Moreau, N., Wicek, F., Anduze, M., Boudry, V., Brient, J-C., Jeans, D., De Freitas, P. Mora, Musat, G., Reinhard, M., Ruan, M., Videau, H., Bulanek, B., Zacek, J., Cvach, J., Gallus, P., Havranek, M., Janata, M., Kvasnicka, J., Lednicky, D., Marcisovsky, M., Polak, I., Popule, J., Tomasek, L., Tomasek, M., Ruzicka, P., Sicho, P., Smolik, J., Vrba, V., Zalesak, J., Belhorma, B., Ghazlane, H., Takeshita, T., and Uozumi, S.

Abstract

To be submitted to JINST, The energy resolution of a highly granular 1 m3 analogue scintillator-steel hadronic calorimeter is studied using charged pions with energies from 10 GeV to 80 GeV at the CERN SPS. The energy resolution for single hadrons is determined to be approximately 58%/sqrt(E/GeV}. This resolution is improved to approximately 45%/sqrt(E/GeV) with software compensation techniques. These techniques take advantage of the event-by-event information about the substructure of hadronic showers which is provided by the imaging capabilities of the calorimeter. The energy reconstruction is improved either with corrections based on the local energy density or by applying a single correction factor to the event energy sum derived from a global measure of the shower energy density. The application of the compensation algorithms to Geant4 simulations yield resolution improvements comparable to those observed for real data.

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