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Your search keyword '"Newell, Diane G."' showing total 11 results
Start Over Author "Newell, Diane G." Publication Type Electronic Resources
11 results on '"Newell, Diane G."'

1. Campylobacter: Animal Reservoirs, Human Infections, and Options for Control

Author

Klinische infectiologie en microb. lab., IRAS OH Epidemiology Microbial Agents, IRAS – One Health Microbial, Infectious Diseases and Immunology - KLIF, Sing, A., Wagenaar, Jaap, Newell, Diane G, Kalupahana, Ruwani S, Mughini Gras, Lapo, Klinische infectiologie en microb. lab., IRAS OH Epidemiology Microbial Agents, IRAS – One Health Microbial, Infectious Diseases and Immunology - KLIF, Sing, A., Wagenaar, Jaap, Newell, Diane G, Kalupahana, Ruwani S, and Mughini Gras, Lapo

Published
2023

3. Campylobacter fetus infections in humans: exposure and disease

Author

LS Klinisch Onderzoek Wagenaar, Faculteit Diergeneeskunde, LS Infectiebiologie (Bacteriologie), I&I SIB2, Strategic Infection Biology, Wagenaar, Jaap A, van Bergen, Marcel A P, Blaser, Martin J, Tauxe, Robert V, Newell, Diane G, van Putten, Jos P M, LS Klinisch Onderzoek Wagenaar, Faculteit Diergeneeskunde, LS Infectiebiologie (Bacteriologie), I&I SIB2, Strategic Infection Biology, Wagenaar, Jaap A, van Bergen, Marcel A P, Blaser, Martin J, Tauxe, Robert V, Newell, Diane G, and van Putten, Jos P M

Published
2014

4. Campylobacter fetus infections in humans: exposure and disease

Author

LS Klinisch Onderzoek Wagenaar, Faculteit Diergeneeskunde, LS Infectiebiologie (Bacteriologie), I&I SIB2, Strategic Infection Biology, Wagenaar, Jaap A, van Bergen, Marcel A P, Blaser, Martin J, Tauxe, Robert V, Newell, Diane G, van Putten, Jos P M, LS Klinisch Onderzoek Wagenaar, Faculteit Diergeneeskunde, LS Infectiebiologie (Bacteriologie), I&I SIB2, Strategic Infection Biology, Wagenaar, Jaap A, van Bergen, Marcel A P, Blaser, Martin J, Tauxe, Robert V, Newell, Diane G, and van Putten, Jos P M

Published
2014

5. Campylobacter fetus infections in humans: exposure and disease

Author

LS Klinisch Onderzoek Wagenaar, Faculteit Diergeneeskunde, LS Infectiebiologie (Bacteriologie), I&I SIB2, Strategic Infection Biology, Wagenaar, Jaap A, van Bergen, Marcel A P, Blaser, Martin J, Tauxe, Robert V, Newell, Diane G, van Putten, Jos P M, LS Klinisch Onderzoek Wagenaar, Faculteit Diergeneeskunde, LS Infectiebiologie (Bacteriologie), I&I SIB2, Strategic Infection Biology, Wagenaar, Jaap A, van Bergen, Marcel A P, Blaser, Martin J, Tauxe, Robert V, Newell, Diane G, and van Putten, Jos P M

Published
2014

6. Genomic Characterization of Campylobacter jejuni strain M1

Author

Friis, Carsten, Wassenaar, Gertrude Maria, Javed, Muhammad A., Snipen, Lars, Lagesen, Karin, Hallin, Peter Fischer, Newell, Diane G., Toszeghy, Monique, Ridley, Anne, Manning, Georgia, Ussery, David, Friis, Carsten, Wassenaar, Gertrude Maria, Javed, Muhammad A., Snipen, Lars, Lagesen, Karin, Hallin, Peter Fischer, Newell, Diane G., Toszeghy, Monique, Ridley, Anne, Manning, Georgia, and Ussery, David

Abstract

Campylobacter jejuni strain M1 (laboratory designation 99/308) is a rarely documented case of direct transmission of C. jejuni from chicken to a person, resulting in enteritis. We have sequenced the genome of C. jejuni strain M1, and compared this to 12 other C. jejuni sequenced genomes currently publicly available. Compared to these, M1 is closest to strain 81116. Based on the 13 genome sequences, we have identified the C. jejuni pan-genome, as well as the core genome, the auxiliary genes, and genes unique between strains M1 and 81116. The pan-genome contains 2,427 gene families, whilst the core genome comprised 1,295 gene families, or about two-thirds of the gene content of the average of the sequenced C. jejuni genomes. Various comparison and visualization tools were applied to the 13 C. jejuni genome sequences, including a species pan- and core genome plot, a BLAST Matrix and a BLAST Atlas. Trees based on 16S rRNA sequences and on the total gene families in each genome are presented. The findings are discussed in the background of the proven virulence potential of M1.

Published
2010

7. Genomic Characterization of Campylobacter jejuni strain M1

Author

Friis, Carsten, Wassenaar, Gertrude Maria, Javed, Muhammad A., Snipen, Lars, Lagesen, Karin, Hallin, Peter Fischer, Newell, Diane G., Toszeghy, Monique, Ridley, Anne, Manning, Georgia, Ussery, David, Friis, Carsten, Wassenaar, Gertrude Maria, Javed, Muhammad A., Snipen, Lars, Lagesen, Karin, Hallin, Peter Fischer, Newell, Diane G., Toszeghy, Monique, Ridley, Anne, Manning, Georgia, and Ussery, David

Abstract

Campylobacter jejuni strain M1 (laboratory designation 99/308) is a rarely documented case of direct transmission of C. jejuni from chicken to a person, resulting in enteritis. We have sequenced the genome of C. jejuni strain M1, and compared this to 12 other C. jejuni sequenced genomes currently publicly available. Compared to these, M1 is closest to strain 81116. Based on the 13 genome sequences, we have identified the C. jejuni pan-genome, as well as the core genome, the auxiliary genes, and genes unique between strains M1 and 81116. The pan-genome contains 2,427 gene families, whilst the core genome comprised 1,295 gene families, or about two-thirds of the gene content of the average of the sequenced C. jejuni genomes. Various comparison and visualization tools were applied to the 13 C. jejuni genome sequences, including a species pan- and core genome plot, a BLAST Matrix and a BLAST Atlas. Trees based on 16S rRNA sequences and on the total gene families in each genome are presented. The findings are discussed in the background of the proven virulence potential of M1.

Published
2010

8. Immunity to Campylobacter: its role in risk assessment and epidemiology

Author

LS IRAS VPH MBR (microbiol.risico sch.), LS Klinisch Onderzoek Wagenaar, LS Infectiebiologie (Bacteriologie), Havelaar, Arie H, van Pelt, Wilfrid, Ang, C Wim, Wagenaar, Jaap A, van Putten, Jos P M, Gross, Uwe, Newell, Diane G, LS IRAS VPH MBR (microbiol.risico sch.), LS Klinisch Onderzoek Wagenaar, LS Infectiebiologie (Bacteriologie), Havelaar, Arie H, van Pelt, Wilfrid, Ang, C Wim, Wagenaar, Jaap A, van Putten, Jos P M, Gross, Uwe, and Newell, Diane G

Published
2009

9. Immunity to Campylobacter: its role in risk assessment and epidemiology

Author

LS IRAS VPH MBR (microbiol.risico sch.), LS Klinisch Onderzoek Wagenaar, LS Infectiebiologie (Bacteriologie), Havelaar, Arie H, van Pelt, Wilfrid, Ang, C Wim, Wagenaar, Jaap A, van Putten, Jos P M, Gross, Uwe, Newell, Diane G, LS IRAS VPH MBR (microbiol.risico sch.), LS Klinisch Onderzoek Wagenaar, LS Infectiebiologie (Bacteriologie), Havelaar, Arie H, van Pelt, Wilfrid, Ang, C Wim, Wagenaar, Jaap A, van Putten, Jos P M, Gross, Uwe, and Newell, Diane G

Published
2009

10. Immunity to Campylobacter: its role in risk assessment and epidemiology

Author

LS IRAS VPH MBR (microbiol.risico sch.), LS Klinisch Onderzoek Wagenaar, LS Infectiebiologie (Bacteriologie), Havelaar, Arie H, van Pelt, Wilfrid, Ang, C Wim, Wagenaar, Jaap A, van Putten, Jos P M, Gross, Uwe, Newell, Diane G, LS IRAS VPH MBR (microbiol.risico sch.), LS Klinisch Onderzoek Wagenaar, LS Infectiebiologie (Bacteriologie), Havelaar, Arie H, van Pelt, Wilfrid, Ang, C Wim, Wagenaar, Jaap A, van Putten, Jos P M, Gross, Uwe, and Newell, Diane G

Published
2009

11. Antigenicity of Campylobacter Jejuni Flagella

Author

VETERANS ADMINISTRATION MEDICAL CENTER DENVER CO, Blaser, Martin J., Hopkins, Janet A., Perez-Perez, Guillermo I., Cody, Henry J., Newell, Diane G., VETERANS ADMINISTRATION MEDICAL CENTER DENVER CO, Blaser, Martin J., Hopkins, Janet A., Perez-Perez, Guillermo I., Cody, Henry J., and Newell, Diane G.

Abstract

We studied the antigenicity of a wild-type flagellate and motile F(+) M(+) Campylobacter jejuni strain (81116) and two daughter mutants, one flagellate and immotile F (+)M(-) and one aflagellate and immotile F(-)M(-). By solium dodecyl sulfate-polyacrylamide gel electrophoresis of acid-extracted surface proteins, a 63-kilodalton (kDa) band identified from sheared flagella as the flagellar protein was present in the F(+)M(+) and F(+)M(-) strains but not in the F(-)M(-) strain. No other differences in protein profile among the three strains were noted. By Western blotting, serum from rabbits immunized with either the F(+)M(+) or F(-)M(-) strain detected a 63-kDa protein in the F(+)M(+) and F(+)M(-) strains but not in the F(-)M(-) strain. That the F(-)M(-) antiserum recognized the 63-kDa band suggests that small amounts of this protein or a cross-reacting antigen is present on the F(-)M(-) strain. By counterimmunoelectrophoresis of the acid-extracted preparations with immune sera, all three strains were found to share three major antigens, but a fourth antigen with a net positive charge was present only in the F(+)M(+) and F(+)M(-) strains. Antisera to five C. jejuni and two Campylobacter fetus strains recognized the 63-kDa protein oif purified F(+)M(+) flagella in Western blots, demonstrating that a common antigen is present, but enzyme-linked immunosorbent assay results suggest that the sharing of this antigen among Campylobacter strains is variable

Published
1986

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