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222 results on '"Meng, Xiang"'

1. On the surface helium abundance of B-type hot subdwarf stars from the WD+MS channel of Type Ia supernovae

Author: Ji, Rui-Jie, Meng, Xiang-Cun, Liu, Zheng-Wei, Ji, Rui-Jie, Meng, Xiang-Cun, and Liu, Zheng-Wei
Abstract: The origin of intermediate helium (He)-rich hot subdwarfs are still unclear. Previous studies have suggested that some surviving Type Ia supernovae (SNe Ia) companions from the white dwarf~+~main-sequence (WD+MS) channel may contribute to the intermediate He-rich hot subdwarfs. However, previous studies ignored the impact of atomic diffusion on the post-explosion evolution of surviving companion stars of SNe Ia, leading to that they could not explain the observed surface He abundance of intermediate He-rich hot subdwarfs. In this work, by taking the atomic diffusion and stellar wind into account, we trace the surviving companions of SNe Ia from the WD+MS channel using the one-dimensional stellar evolution code \textsc{MESA} until they evolve into hot subdwarfs. We find that the surface He-abundances of our surviving companion models during their core He-burning phases are in a range of $-1 \lesssim {\rm log}(N_{\rm He}/N_{\rm H}) \lesssim 0$, which are consistent with those observed in intermediate He-rich hot subdwarfs. This seems to further support that surviving companions of SNe Ia in the WD+MS channel are possible to form some intermediate He-rich hot subdwarfs., Comment: 10 pages, 5 figures
Published: 2024

2. OSSCAR: One-Shot Structured Pruning in Vision and Language Models with Combinatorial Optimization

Author: Meng, Xiang, Ibrahim, Shibal, Behdin, Kayhan, Hazimeh, Hussein, Ponomareva, Natalia, Mazumder, Rahul, Meng, Xiang, Ibrahim, Shibal, Behdin, Kayhan, Hazimeh, Hussein, Ponomareva, Natalia, and Mazumder, Rahul
Abstract: Structured pruning is a promising approach for reducing the inference costs of large vision and language models. By removing carefully chosen structures, e.g., neurons or attention heads, the improvements from this approach can be realized on standard deep learning hardware. In this work, we focus on structured pruning in the one-shot (post-training) setting, which does not require model retraining after pruning. We propose a novel combinatorial optimization framework for this problem, based on a layer-wise reconstruction objective and a careful reformulation that allows for scalable optimization. Moreover, we design a new local combinatorial optimization algorithm, which exploits low-rank updates for efficient local search. Our framework is time and memory-efficient and considerably improves upon state-of-the-art one-shot methods on vision models (e.g., ResNet50, MobileNet) and language models (e.g., OPT-1.3B -- OPT-30B). For language models, e.g., OPT-2.7B, OSSCAR can lead to $125\times$ lower test perplexity on WikiText with $2\times$ inference time speedup in comparison to the state-of-the-art ZipLM approach. Our framework is also $6\times$ -- $8\times$ faster. Notably, our work considers models with tens of billions of parameters, which is up to $100\times$ larger than what has been previously considered in the structured pruning literature.
Published: 2024

3. FALCON: FLOP-Aware Combinatorial Optimization for Neural Network Pruning

Author: Meng, Xiang, Chen, Wenyu, Benbaki, Riade, Mazumder, Rahul, Meng, Xiang, Chen, Wenyu, Benbaki, Riade, and Mazumder, Rahul
Abstract: The increasing computational demands of modern neural networks present deployment challenges on resource-constrained devices. Network pruning offers a solution to reduce model size and computational cost while maintaining performance. However, most current pruning methods focus primarily on improving sparsity by reducing the number of nonzero parameters, often neglecting other deployment costs such as inference time, which are closely related to the number of floating-point operations (FLOPs). In this paper, we propose FALCON, a novel combinatorial-optimization-based framework for network pruning that jointly takes into account model accuracy (fidelity), FLOPs, and sparsity constraints. A main building block of our approach is an integer linear program (ILP) that simultaneously handles FLOP and sparsity constraints. We present a novel algorithm to approximately solve the ILP. We propose a novel first-order method for our optimization framework which makes use of our ILP solver. Using problem structure (e.g., the low-rank structure of approx. Hessian), we can address instances with millions of parameters. Our experiments demonstrate that FALCON achieves superior accuracy compared to other pruning approaches within a fixed FLOP budget. For instance, for ResNet50 with 20% of the total FLOPs retained, our approach improves the accuracy by 48% relative to state-of-the-art. Furthermore, in gradual pruning settings with re-training between pruning steps, our framework outperforms existing pruning methods, emphasizing the significance of incorporating both FLOP and sparsity constraints for effective network pruning.
Published: 2024

4. Regulation of the differential expression of members of the Vitellogenin gene family in zebrafish, Danio Rerio

Author: Meng, Xiang
Subjects: 597.482
Abstract: Environmental oestrogens have adverse effects on fish development and reproduction. The availability of models to study the differential effects of endogenous and exogenous oestrogens and to test for endocrine disrupting chemicals (EDCs) would be advantageous. Vitellogenins (VTGs) are precursors of egg yolk proteins and phospho-lipo-glycoproteins, and belong to a large lipid transfer protein superfamily. VTGs are synthesised differentially in the liver of females under the oestrogenic regulation of the oestrogen receptor (ER) and are distributed to oocytes via the circulatory system. During the last decade, in vitro systems such as fish cell lines have become very important in aquatic ecotoxicology. Thus, a zebrafish liver cell line (ZFL, CRL-2643) was developed for the investigation of VTGs and ERs induction potential oestrogens (E2/EE2). Surprisingly the levels of transcribed ERa and VTGs are very low in ZFL cells and cannot be induced by oestrogens. The weak ERa mRNA was proposed to be the crucial reason of negative VTG induction in responses of oestrogens. Therefore, a recombinant ERa (human Esrl) plasmid 'was subsequently constructed and transfected into ZFL cells. Due to the low efficiency of transfection, Esr 1 stable transfected ZFL cells were only obtained after a long period of selection. However, an unexplained protein band was detected in Esrl transfected cells by western blot. Conversely, the expression of Esrl protein was detected in Esrl transient transfected EcoPack cells (HEK-293) with higher transfection efficiency in parallel assays. Polycyclic aromatic hydrocarbons (PAHs) are suspected to have inhibitory effects on the expression of VTG and ER genes in fish liver through aryl hydrocarbon receptor (AhR) which is a ligand activated transcription factor stimulating the expression of the genes encoding xenobiotic metabolizing enzymes such as cytochrome P450-1A (CYP-IA). ~- naphthoflavone (bNF) is a potent agonist of AhR and also an inducer of such detoxification enzymes as CYPs. As expected, the prominent induction of CYP-IA was detected in ZFL cells by bNF exposure. This result indicated the characterization of hepatic mechanism in ZFL cells and initiated the investigation of the mechanism behind the cross-talk between ERs and AhRs under the combination exposure (bNF and EE2). The results of quantitative real-time, reverse-transcriptase polymerase chain reaction (qPCR) assays revealed that transcript levels of CYP-IA and AhR2 were increased by bNF exposure in a time- and concentration-dependent manner, but no significant effect in AhRls or ERs, whereas ER~2 seemed to be repressed by bNF. There are multiple VTG genes and an in silico analysis of their distribution in the zebrafish genome has identified eight genes (VTG-l to -8) and a pseudogene (VTG-9). A cluster of eight VTGs is located in a single 271 kbp region of chromosome 22, whereas a single gene (VTG-3) is mapped on chromosome 11. Sequence analyses of nucleotide and protein show extensive identity between VTG-l, -4 to -7 and -9 which share a domain structure (LvH- Pv-LvL), and VTG-2 is similar to -8 in terms of length and the presence of a von Willebrand Factor domain (LvH-Pv-LvL-vWFD) whereas VTG-3 is dissimilar in sequence and structural features since it lacks the phosvitin domain (LvH-LvL). qPCR assays were developed to measure transcripts of all VTG and ER genes in adult livers. Transcript levels of VTGs and ERs in vitellogenic female were ordered: VTG-l»VTG-2::::VTG-5>VTG- 4>VTG-6>VTG-7>VTG-3»VTG-8>VTG-9 and ERa>ER~2»ER~I, respectively. In male liver, transcript levels ofVTGs, ERa and ER~1 were undetectable or very low while ER~2 transcript was present in appreciable quantity. According to the genomic organization and phylogenetic analysis, it was speculated that the origin and evolution of multiple VTG genes in zebrafish was based on a number of whole genome duplications (WGDs), gene duplications and conversion events. Furthermore, tests for selection suggested that VTGs in zebrafish had undergone purifying selection in combination with mixed process of concerted and birth-and-death evolution.
Published: 2011

5. Failure to experimentally infect 10 days-old piglets with a cell culture-propagated infectious stock of a classical genotype 1a porcine epidemic diarrhea virus

Author: Virologie, Infectious Diseases and Immunology - Virology, Gerber, Priscilla F, Cao, Dianjun, Xiao, Chao-Ting, Chen, Qi, Lager, Kelly, Bosch, Berend Jan, Meng, Xiang-Jin, Halbur, Patrick G, Opriessnig, Tanja, Virologie, Infectious Diseases and Immunology - Virology, Gerber, Priscilla F, Cao, Dianjun, Xiao, Chao-Ting, Chen, Qi, Lager, Kelly, Bosch, Berend Jan, Meng, Xiang-Jin, Halbur, Patrick G, and Opriessnig, Tanja
Published: 2023

6. Probing Parity Violation in the Stochastic Gravitational Wave Background with Astrometry

Author: Liang, Qiuyue, Lin, Meng-Xiang, Trodden, Mark, Wong, Sam S. C., Liang, Qiuyue, Lin, Meng-Xiang, Trodden, Mark, and Wong, Sam S. C.
Abstract: Astrometry holds the potential for testing fundamental physics through the effects of the Stochastic Gravitational Wave Background (SGWB) in the $\sim 1-100$ nHz frequency band on precision measurements of stellar positions. Such measurements are complementary to tests made possible by the detection of the SGWB using Pulsar Timing Arrays. Here, the feasibility of using astrometry for the identification of parity-violating signals within the SGWB is investigated. This is achieved by defining and quantifying a non-vanishing $EB$ correlation function within astrometric correlation functions, and investigating how one might estimate the detectability of such signals., Comment: 7 pages, 2 figures
Published: 2023

7. Late Time Modification of Structure Growth and the S8 Tension

Author: Lin, Meng-Xiang, Jain, Bhuvnesh, Raveri, Marco, Baxter, Eric J., Chang, Chihway, Gatti, Marco, Lee, Sujeong, Muir, Jessica, Lin, Meng-Xiang, Jain, Bhuvnesh, Raveri, Marco, Baxter, Eric J., Chang, Chihway, Gatti, Marco, Lee, Sujeong, and Muir, Jessica
Abstract: The $S_8$ tension between low-redshift galaxy surveys and the primary CMB signals a possible breakdown of the $\Lambda$CDM model. Recently differing results have been obtained using low-redshift galaxy surveys and the higher redshifts probed by CMB lensing, motivating a possible time-dependent modification to the growth of structure. We investigate a simple phenomenological model in which the growth of structure deviates from the $\Lambda$CDM prediction at late times, in particular as a simple function of the dark energy density. Fitting to galaxy lensing, CMB lensing, BAO, and Supernovae datasets, we find significant evidence - 2.5 - 3$\sigma$, depending on analysis choices - for a non-zero value of the parameter quantifying a deviation from $\Lambda$CDM. The preferred model, which has a slower growth of structure below $z\sim 1$, improves the joint fit to the data over $\Lambda$CDM. While the overall fit is improved, there is weak evidence for galaxy and CMB lensing favoring different changes in the growth of structure., Comment: Match the published version. Add more references. 6 pages, 5 figures, 1 table
Published: 2023
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8. A Test of Gravity with Pulsar Timing Arrays

Author: Liang, Qiuyue, Lin, Meng-Xiang, Trodden, Mark, Liang, Qiuyue, Lin, Meng-Xiang, and Trodden, Mark
Abstract: A successful measurement of the Stochastic Gravitational Wave Background (SGWB) in Pulsar Timing Arrays (PTAs) would open up a new window through which to test the predictions of General Relativity (GR). We consider how these measurements might reveal deviations from GR by studying the overlap reduction function -- the quantity that in GR is approximated by the Hellings-Downs curve -- in some sample modifications of gravity, focusing on the generic prediction of a modified dispersion relation for gravitational waves. We find a distinct signature of such modifications to GR -- a shift in the minimum angle of the angular distribution -- and demonstrate that this shift is quantitatively sensitive to any change in the phase velocity. In a given modification of gravity, this result can be used, in some regions of parameter space, to distinguish the effect of a modified dispersion relation from that due to the presence of extra polarization modes., Comment: v2: add references and discussions. 23 pages, 4 figures
Published: 2023

9. Fetal Loss in Pregnant Rabbits Infected with Genotype 3 Hepatitis E Virus Is Associated with Altered Inflammatory Responses, Enhanced Virus Replication, and Extrahepatic Virus Dissemination with Positive Correlations with Increased Estradiol Level

Author: Mahsoub, Hassan M. M., Heffron, C. Lynn, Hassebroek, Anna M. M., Sooryanarain, Harini, Wang, Bo, LeRoith, Tanya, Rodriguez, Guillermo Raimundi, Tian, Debin, Meng, Xiang-Jin, Mahsoub, Hassan M. M., Heffron, C. Lynn, Hassebroek, Anna M. M., Sooryanarain, Harini, Wang, Bo, LeRoith, Tanya, Rodriguez, Guillermo Raimundi, Tian, Debin, and Meng, Xiang-Jin
Abstract: HEV causes adverse pregnancy outcomes, with a mortality rate of >30% in pregnant women, but the underlying mechanisms are poorly understood. In this study, we utilized HEV-3ra and its cognate host (pregnant rabbit) to delineate the potential underlying mechanisms of pregnancy-associated adverse outcomes during HEV infection. Hepatitis E virus (HEV) causes adverse clinical outcomes in pregnant women, but the underlying mechanisms remain poorly understood. To delineate the mechanisms of pregnancy-associated adverse effects during HEV infection, we utilized a genotype 3 HEV from rabbit (HEV-3ra) and its cognate host (rabbits) to systematically investigate the clinical consequences, viral replication dynamics, and host immune and hormonal responses of HEV infection during pregnancy. We found a significant fetal loss of 23% in HEV-infected pregnant rabbits, indicating an early-stage miscarriage. HEV infection in pregnant rabbits was characterized by higher viral loads in feces, intestinal contents, liver, and spleen tissues, as well as a longer and earlier onset of viremia than in infected nonpregnant rabbits. HEV infection altered the pattern of cytokine gene expressions in the liver of pregnant rabbits and caused a transient increase of serum interferon gamma (IFN-gamma) shortly after a notable increase in viral replication, which may contribute to early fetal loss. Histological lesions in the spleen were more pronounced in infected pregnant rabbits, although moderate liver lesions were seen in both infected pregnant and nonpregnant rabbits. Total bilirubin was elevated in infected pregnant rabbits. The serum levels of estradiol (E2) in HEV-infected pregnant rabbits were significantly higher than those in mock-infected pregnant rabbits at 14 days postinoculation (dpi) and correlated positively with higher viral loads in feces, liver, and spleen tissues at 28 dpi, suggesting that it may play a role in extrahepatic virus dissemination. The results have important implicat
Published: 2023

10. Fast as CHITA: Neural Network Pruning with Combinatorial Optimization

Author: Benbaki, Riade, Chen, Wenyu, Meng, Xiang, Hazimeh, Hussein, Ponomareva, Natalia, Zhao, Zhe, Mazumder, Rahul, Benbaki, Riade, Chen, Wenyu, Meng, Xiang, Hazimeh, Hussein, Ponomareva, Natalia, Zhao, Zhe, and Mazumder, Rahul
Abstract: The sheer size of modern neural networks makes model serving a serious computational challenge. A popular class of compression techniques overcomes this challenge by pruning or sparsifying the weights of pretrained networks. While useful, these techniques often face serious tradeoffs between computational requirements and compression quality. In this work, we propose a novel optimization-based pruning framework that considers the combined effect of pruning (and updating) multiple weights subject to a sparsity constraint. Our approach, CHITA, extends the classical Optimal Brain Surgeon framework and results in significant improvements in speed, memory, and performance over existing optimization-based approaches for network pruning. CHITA's main workhorse performs combinatorial optimization updates on a memory-friendly representation of local quadratic approximation(s) of the loss function. On a standard benchmark of pretrained models and datasets, CHITA leads to significantly better sparsity-accuracy tradeoffs than competing methods. For example, for MLPNet with only 2% of the weights retained, our approach improves the accuracy by 63% relative to the state of the art. Furthermore, when used in conjunction with fine-tuning SGD steps, our method achieves significant accuracy gains over the state-of-the-art approaches.
Published: 2023

11. An exact penalty approach for optimization with nonnegative orthogonality constraints

Author: Massachusetts Institute of Technology. Operations Research Center, Jiang, Bo, Meng, Xiang, Wen, Zaiwen, Chen, Xiaojun, Massachusetts Institute of Technology. Operations Research Center, Jiang, Bo, Meng, Xiang, Wen, Zaiwen, and Chen, Xiaojun
Abstract: Optimization with nonnegative orthogonality constraints has wide applications in machine learning and data sciences. It is NP-hard due to some combinatorial properties of the constraints. We first propose an equivalent optimization formulation with nonnegative and multiple spherical constraints and an additional single nonlinear constraint. Various constraint qualifications, the first- and second-order optimality conditions of the equivalent formulation are discussed. By establishing a local error bound of the feasible set, we design a class of (smooth) exact penalty models via keeping the nonnegative and multiple spherical constraints. The penalty models are exact if the penalty parameter is sufficiently large but finite. A practical penalty algorithm with postprocessing is then developed to approximately solve a series of subproblems with nonnegative and multiple spherical constraints. We study the asymptotic convergence and establish that any limit point is a weakly stationary point of the original problem and becomes a stationary point under some additional mild conditions. Extensive numerical results on the problem of computing the orthogonal projection onto nonnegative orthogonality constraints, the orthogonal nonnegative matrix factorization problems and the K-indicators model show the effectiveness of our proposed approach.
Published: 2023

12. Ribavirin Treatment Failure-Associated Mutation, Y1320H, in the RNA-Dependent RNA Polymerase of Genotype 3 Hepatitis E Virus (HEV) Enhances Virus Replication in a Rabbit HEV Infection Model

Author: Wang, Bo, Mahsoub, Hassan M. M., Li, Wen, Heffron, C. Lynn, Tian, Debin, Hassebroek, Anna M. M., LeRoith, Tanya, Meng, Xiang-Jin, Wang, Bo, Mahsoub, Hassan M. M., Li, Wen, Heffron, C. Lynn, Tian, Debin, Hassebroek, Anna M. M., LeRoith, Tanya, and Meng, Xiang-Jin
Abstract: HEV-3 causes chronic hepatitis E that requires antiviral therapy in immunosuppressed individuals. RBV is the main therapeutic option for chronic hepatitis E as an off-label use. Chronic hepatitis E virus (HEV) infection has become a significant clinical problem that requires treatment in immunocompromised individuals. In the absence of an HEV-specific antiviral, ribavirin (RBV) has been used off-label, but treatment failure may occur due to mutations in the viral RNA-dependent RNA polymerase (RdRp), including Y1320H, K1383N, and G1634R. Chronic hepatitis E is mostly caused by zoonotic genotype 3 HEV (HEV-3), and HEV variants from rabbits (HEV-3ra) are closely related to human HEV-3. Here, we explored whether HEV-3ra, along with its cognate host, can serve as a model to study RBV treatment failure-associated mutations observed in human HEV-3-infected patients. By utilizing the HEV-3ra infectious clone and indicator replicon, we generated multiple single mutants (Y1320H, K1383N, K1634G, and K1634R) and a double mutant (Y1320H/K1383N) and assessed the role of mutations on replication and antiviral activity of HEV-3ra in cell culture. Furthermore, we also compared the replication of the Y1320H mutant with the wild-type HEV-3ra in experimentally infected rabbits. Our in vitro analyses revealed that the effects of these mutations on rabbit HEV-3ra are altogether highly consistent with those on human HEV-3. Importantly, we found that the Y1320H enhances virus replication during the acute stage of HEV-3ra infection in rabbits, which corroborated our in vitro results showing an enhanced viral replication of Y1320H. Taken together, our data suggest that HEV-3ra and its cognate host is a useful and relevant naturally occurring homologous animal model to study the clinical relevance of antiviral-resistant mutations observed in human HEV-3 chronically-infected patients.IMPORTANCE HEV-3 causes chronic hepatitis E that requires antiviral therapy in immunosuppressed individuals. RB
Published: 2023

13. Human Pose-based Estimation, Tracking and Action Recognition with Deep Learning: A Survey

Author: Zhou, Lijuan, Meng, Xiang, Liu, Zhihuan, Wu, Mengqi, Gao, Zhimin, Wang, Pichao, Zhou, Lijuan, Meng, Xiang, Liu, Zhihuan, Wu, Mengqi, Gao, Zhimin, and Wang, Pichao
Abstract: Human pose analysis has garnered significant attention within both the research community and practical applications, owing to its expanding array of uses, including gaming, video surveillance, sports performance analysis, and human-computer interactions, among others. The advent of deep learning has significantly improved the accuracy of pose capture, making pose-based applications increasingly practical. This paper presents a comprehensive survey of pose-based applications utilizing deep learning, encompassing pose estimation, pose tracking, and action recognition.Pose estimation involves the determination of human joint positions from images or image sequences. Pose tracking is an emerging research direction aimed at generating consistent human pose trajectories over time. Action recognition, on the other hand, targets the identification of action types using pose estimation or tracking data. These three tasks are intricately interconnected, with the latter often reliant on the former. In this survey, we comprehensively review related works, spanning from single-person pose estimation to multi-person pose estimation, from 2D pose estimation to 3D pose estimation, from single image to video, from mining temporal context gradually to pose tracking, and lastly from tracking to pose-based action recognition. As a survey centered on the application of deep learning to pose analysis, we explicitly discuss both the strengths and limitations of existing techniques. Notably, we emphasize methodologies for integrating these three tasks into a unified framework within video sequences. Additionally, we explore the challenges involved and outline potential directions for future research., Comment: 47 pages
Published: 2023

14. Answering Subjective Induction Questions on Products by Summarizing Multi-sources Multi-viewpoints Knowledge

Author: Zhang, Yufeng, Wang, Meng-xiang, Yu, Jianxing, Zhang, Yufeng, Wang, Meng-xiang, and Yu, Jianxing
Abstract: This paper proposes a new task in the field of Answering Subjective Induction Question on Products (SUBJPQA). The answer to this kind of question is non-unique, but can be interpreted from many perspectives. For example, the answer to 'whether the phone is heavy' has a variety of different viewpoints. A satisfied answer should be able to summarize these subjective opinions from multiple sources and provide objective knowledge, such as the weight of a phone. That is quite different from the traditional QA task, in which the answer to a factoid question is unique and can be found from a single data source. To address this new task, we propose a three-steps method. We first retrieve all answer-related clues from multiple knowledge sources on facts and opinions. The implicit commonsense facts are also collected to supplement the necessary but missing contexts. We then capture their relevance with the questions by interactive attention. Next, we design a reinforcement-based summarizer to aggregate all these knowledgeable clues. Based on a template-controlled decoder, we can output a comprehensive and multi-perspective answer. Due to the lack of a relevant evaluated benchmark set for the new task, we construct a large-scale dataset, named SupQA, consisting of 48,352 samples across 15 product domains. Evaluation results show the effectiveness of our approach., Comment: 1. There are some errors in the data analysis table in the dataset SupQA, which needs to be corrected. 2. There is something wrong with the partial expression of the formula. 3. It will be resubmitted after modification
Published: 2023

15. Distinctive egg-laying patterns in terminal versus non-terminal periods in three fruit fly species.

Author: Meng, Xiang, Meng, Xiang, Hu, Junjie, Plant, Richard E, Carpenter, Tim E, Carey, James R, Meng, Xiang, Meng, Xiang, Hu, Junjie, Plant, Richard E, Carpenter, Tim E, and Carey, James R
Abstract: The specific objective of this study was to use a logistic regression model for determining the degree to which egg laying patterns of individual females at the end of life (i.e., terminal segments) in each of three different fruit fly species could be distinguished from the egg-laying patterns over a similar period in midlife (i.e., non-terminal segments). Extracting data from large-scale databases for 11-day terminal and 11-day non-terminal segments in the vinegar fly (Drosophila melanogaster), the Mexican fruit fly (Anastrepha ludens) and the Mediterranean fruit fly (Ceratitis capitata) and organizing the model's results in a 2 × 2 contingency table, we found that: (1) daily egg-laying patterns in fruit flies can be used to distinguish terminal from non-terminal periods; (2) the overall performance metrics such as precision, accuracy, false positives and true negatives depended heavily on species; (3) differentiating between terminal and non-terminal segments is more difficult when flies die at younger ages; and (4) among the three species the best performing metrics including accuracy and precision were those produced using data on D. melanogaster. We conclude that, although the reliability of the prediction of whether a segment occurred at the end of life is relatively high for most species, it does not follow precisely predicting remaining life will also be highly reliable since classifying an end of life period is a fundamentally different challenge than is predicting an exact day of death.
Published: 2021

16. Modified gravitational wave propagation with higher modes and its degeneracies with lensing

Author: Ezquiaga, Jose Maria, Hu, Wayne, Lagos, Macarena, Lin, Meng-Xiang, Xu, Fei, Ezquiaga, Jose Maria, Hu, Wayne, Lagos, Macarena, Lin, Meng-Xiang, and Xu, Fei
Abstract: Low-energy alternatives to General Relativity (GR) generically modify the phase of gravitational waves (GWs) during their propagation. As detector sensitivities increase, it becomes key to understand how these modifications affect the GW higher modes and to disentangle possible degeneracies with astrophysical phenomena. We apply a general formalism -- the WKB approach -- for solving analytically wave propagation in the spatial domain with a modified dispersion relation (MDR). We compare this WKB approach to applying a stationary phase approximation (SPA) in the temporal domain with time delays associated to the group or particle velocity. To this end, we extend the SPA to generic signals with higher modes, keeping careful track of reference phases and arrival times. We find that the WKB approach coincides with the SPA using the group velocity, in agreement with the principles of wave propagation. We then explore the degeneracies between a GW propagation with an MDR and a strongly-lensed GW in GR, since the latter can introduce a frequency-independent phase shift which is not degenerate with source parameters in the presence of higher modes. We find that for a particular MDR there is an exact degeneracy for wave propagation, unlike with the SPA for particle propagation. For the other cases, we search for the values of the MDR parameters that minimize the $\chi^2$ and conclude that strongly-lensed GR GWs could be misinterpreted as GWs in modified gravity. Future MDR constraints with higher mode GWs should include the possibility of frequency-independent phase shifts, allowing for the identification of modified gravity and strong lensing distortions at the same time., Comment: 32 pages, 6 figures
Published: 2022

17. Selective skeletal editing of polycyclic arenes using organophotoredox dearomative functionalization.

Author: Ji, Peng, Ji, Peng, Davies, Cassondra C, Gao, Feng, Chen, Jing, Meng, Xiang, Houk, Kendall N, Chen, Shuming, Wang, Wei, Ji, Peng, Ji, Peng, Davies, Cassondra C, Gao, Feng, Chen, Jing, Meng, Xiang, Houk, Kendall N, Chen, Shuming, and Wang, Wei
Abstract: Reactions that lead to destruction of aromatic ring systems often require harsh conditions and, thus, take place with poor selectivities. Selective partial dearomatization of fused arenes is even more challenging but can be a strategic approach to creating versatile, complex polycyclic frameworks. Herein we describe a general organophotoredox approach for the chemo- and regioselective dearomatization of structurally diverse polycyclic aromatics, including quinolines, isoquinolines, quinoxalines, naphthalenes, anthracenes and phenanthrenes. The success of the method for chemoselective oxidative rupture of aromatic moieties relies on precise manipulation of the electronic nature of the fused polycyclic arenes. Mechanistic studies show that the addition of a hydrogen atom transfer (HAT) agent helps favor the dearomatization pathway over the more thermodynamically downhill aromatization pathway. We show that this strategy can be applied to rapid synthesis of biologically valued targets and late-stage skeletal remodeling en route to complex structures.
Published: 2022

18. A Dark Matter Trigger for Early Dark Energy Coincidence

Author: Lin, Meng-Xiang, McDonough, Evan, Hill, J. Colin, Hu, Wayne, Lin, Meng-Xiang, McDonough, Evan, Hill, J. Colin, and Hu, Wayne
Abstract: Early dark energy (EDE), whose cosmological role is localized in time around the epoch of matter-radiation equality in order to resolve the Hubble tension, introduces a new coincidence problem: why should the EDE dynamics occur near equality if EDE is decoupled from both matter and radiation? The resolution of this problem may lie in an {\it early dark sector} (EDS), wherein the dark matter mass is dependent on the EDE scalar field. Concretely, we consider a Planck-suppressed coupling of EDE to dark matter, as would naturally arise from breaking of the global $U(1)$ shift symmetry of the former by quantum gravity effects. With a sufficiently flat potential, the rise to dominance of dark matter at matter-radiation equality itself triggers the rolling and subsequent decay of the EDE. We show that this {\it trigger} EDS (tEDS) model can naturally resolve the EDE coincidence problem at the background level without any fine tuning of the coupling to dark matter or of the initial conditions. When fitting to current cosmological data, including that from the local distance ladder and the low-redshift amplitude of fluctuations, the tEDS maximum-likelihood model performs comparably to EDE for resolving the Hubble tension, achieving $H_0 =71.2$ km/s/Mpc. However, fitting the \emph{Planck} cosmic microwave background data requires a specific range of initial field positions to balance the scalar field fluctuations that drive acoustic oscillations, providing testable differences with other EDE models., Comment: 12 pages, 6 figures
Published: 2022

19. Two mutations in the ORF1 of genotype 1 hepatitis E virus enhance virus replication and may associate with fulminant hepatic failure

Author: Wang, Bo, Tian, Debin, Sooryanarain, Harini, Mahsoub, Hassan M., Heffron, C. Lynn, Hassebroek, Anna M., Meng, Xiang-Jin, Wang, Bo, Tian, Debin, Sooryanarain, Harini, Mahsoub, Hassan M., Heffron, C. Lynn, Hassebroek, Anna M., and Meng, Xiang-Jin
Abstract: Hepatitis E virus (HEV) infection in pregnant women has a high incidence of developing fulminant hepatic failure (FHF) with significant mortality. Multiple amino acid changes in genotype 1 HEV (HEV-1) are reportedly linked to FHF clinical cases, but experimental confirmation of the roles of these changes in FHF is lacking. By utilizing the HEV-1 indicator replicon and infectious clone, we generated 11 HEV-1 single mutants, each with an individual mutation, and investigated the effect of these mutations on HEV replication and infection in human liver cells. We demonstrated that most of the mutations actually impaired HEV-1 replication efficiency compared with the wild type (WT), likely due to altered physicochemical properties and structural conformations. However, two mutations, A317T and V1120I, significantly increased HEV-1 replication. Notably, these two mutations simultaneously occurred in 100% of 21 HEV-1 variants from patients with FHF in Bangladesh. We further created an HEV-1 A317T/V1120I double mutant and found that it greatly enhanced HEV replication, which may explain the rapid viral replication and severe disease. Furthermore, we tested the effect of these FHF-associated mutations on genotype 3 HEV (HEV-3) replication and found that all the mutants had a reduced level of replication ability and infectivity, which is not unexpected due to distinct infection patterns between HEV-1 and HEV-3. Additionally, we demonstrated that these FHF-associated mutations do not appear to alter their sensitivity to ribavirin (RBV), suggesting that ribavirin remains a viable option for antiviral therapy for patients with FHF. The results have important implications for understanding the mechanism of HEV-1-associated FHF.
Published: 2022

20. ICTV Virus Taxonomy Profile : Hepeviridae 2022

Author: Purdy, Michael A., Drexler, Jan Felix, Meng, Xiang Jin, Norder, Heléne, Okamoto, Hiroaki, Van der Poel, Wim H.M., Reuter, Gábor, de Souza, William M., Ulrich, Rainer G., Smith, Donald B., Purdy, Michael A., Drexler, Jan Felix, Meng, Xiang Jin, Norder, Heléne, Okamoto, Hiroaki, Van der Poel, Wim H.M., Reuter, Gábor, de Souza, William M., Ulrich, Rainer G., and Smith, Donald B.
Abstract: The family Hepeviridae includes enterically transmitted small quasi-enveloped or non-enveloped positive-sense single-stranded RNA viruses infecting mammals and birds (subfamily Orthohepevirinae) or fish (Parahepevirinae). Hepatitis E virus (genus Paslahepevirus) is responsible for self-limiting acute hepatitis in humans; the infection may become chronic in immunocompromised individuals and extrahepatic manifestations have been described. Avian hepatitis E virus (genus Avihepevirus) causes hepatitis-splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hepeviridae, which is available at www.ictv.global/report/hepeviridae.
Published: 2022

21. RESEARCH ON IDEOLOGICAL SECURITY GOVERNANCE OF COLLEGES AND UNIVERSITIES IN THE AGE OF BIG DATA UNDER COGNITIVE DISORDERS

Author: Zhu, Xunchun, Meng, Xiang, Zhu, Xunchun, and Meng, Xiang
Published: 2022

22. THE DEVELOPMENT OF CULTURAL COMMUNICATION THEORY IN BOOK MANAGEMENT OF UNIVERSITY LIBRARY FROM THE PERSPECTIVE OF PSYCHOLOGY

Author: Meng, Xiang and Meng, Xiang
Published: 2022

23. The environments of Type Ia supernovae with different relative equivalent width of Si II feature in their spectra

Author: Meng, Xiang-Cun, Zhang, Ju-Jia, Zhao, Xu-Lin, Li, Li-Ping, Wang, Xiao-Feng, Meng, Xiang-Cun, Zhang, Ju-Jia, Zhao, Xu-Lin, Li, Li-Ping, and Wang, Xiao-Feng
Abstract: Although type Ia supernovae are so important in many astrophysical field, e.g. in cosmology, their explosion mechanism and progenitor system are still unclear. In physics, the relative equivalent width (REW) of the Si II 635.5 nm absorption feature reflects the velocity interval of silicon in the supernova ejecta and then may provide constraints on the explosion mechanism of SNe Ia. In this paper, we divide the SNe Ia into broad line (BL) and normal line (NL) subsamples based on their REW of Si II 635.5 nm absorption lines around maximum light, and find that the BL SNe Ia have a dimmer mean brightness than NL ones, which possibly results from their different metallicities. However, based on the pixel statistics study on the environments of two subsamples, we do not find any significant potential difference on the environments between BL and NL SNe Ia, which implies that the explosion mechanism of SNe Ia could be independent of their progenitor populations., Comment: 17 pages, 13 figures, accepted for publication in ApJ
Published: 2022
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24. Quant-BnB: A Scalable Branch-and-Bound Method for Optimal Decision Trees with Continuous Features

Author: Mazumder, Rahul, Meng, Xiang, Wang, Haoyue, Mazumder, Rahul, Meng, Xiang, and Wang, Haoyue
Abstract: Decision trees are one of the most useful and popular methods in the machine learning toolbox. In this paper, we consider the problem of learning optimal decision trees, a combinatorial optimization problem that is challenging to solve at scale. A common approach in the literature is to use greedy heuristics, which may not be optimal. Recently there has been significant interest in learning optimal decision trees using various approaches (e.g., based on integer programming, dynamic programming) -- to achieve computational scalability, most of these approaches focus on classification tasks with binary features. In this paper, we present a new discrete optimization method based on branch-and-bound (BnB) to obtain optimal decision trees. Different from existing customized approaches, we consider both regression and classification tasks with continuous features. The basic idea underlying our approach is to split the search space based on the quantiles of the feature distribution -- leading to upper and lower bounds for the underlying optimization problem along the BnB iterations. Our proposed algorithm Quant-BnB shows significant speedups compared to existing approaches for shallow optimal trees on various real datasets.
Published: 2022

25. Rosuvastatin Slows Progression of Carotid Intima-Media Thickness: The METEOR-China Randomized Controlled Study

Author: Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Zheng, Huaguang, Li, Hongwei, Wang, Yilong, Li, Zhanquan, Hu, Bo, Li, Xiaogang, Fu, Lu, Hu, Hongtao, Nie, Zhiyu, Zhao, Bilian, Wei, Di, Karlson, Björn W., Bots, Michiel L., Meng, Xiang Wen, Chen, Yundai, Wang, Yongjun, Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Zheng, Huaguang, Li, Hongwei, Wang, Yilong, Li, Zhanquan, Hu, Bo, Li, Xiaogang, Fu, Lu, Hu, Hongtao, Nie, Zhiyu, Zhao, Bilian, Wei, Di, Karlson, Björn W., Bots, Michiel L., Meng, Xiang Wen, Chen, Yundai, and Wang, Yongjun
Published: 2022

26. Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model

Author: Maeda, Denicar Lina Nascimento Fabris, Tian, Debin, Yu, Hanna, Dar, Nakul, Rajasekaran, Vignesh, Meng, Sarah, Mahsoub, Hassan, Sooryanarain, Harini, Wang, Bo, Heffron, C. Lynn, Hassebroek, Anna, LeRoith, Tanya, Meng, Xiang-Jin, Zeichner, Steven L., Maeda, Denicar Lina Nascimento Fabris, Tian, Debin, Yu, Hanna, Dar, Nakul, Rajasekaran, Vignesh, Meng, Sarah, Mahsoub, Hassan, Sooryanarain, Harini, Wang, Bo, Heffron, C. Lynn, Hassebroek, Anna, LeRoith, Tanya, Meng, Xiang-Jin, and Zeichner, Steven L.
Abstract: As the coronavirus disease 2019 (COVID-19) pandemic rages on, it is important to explore new evolution-resistant vaccine antigens and new vaccine platforms that can produce readily scalable, inexpensive vaccines with easier storage and transport. We report here a synthetic biology-based vaccine platform that employs an expression vector with an inducible gram-negative autotransporter to express vaccine antigens on the surface of genome-reduced bacteria to enhance interaction of vaccine antigen with the immune system. As a proof-of-principle, we utilized genome-reduced Escherichia coli to express SARS-CoV-2 and porcine epidemic diarrhea virus (PEDV) fusion peptide (FP) on the cell surface, and evaluated their use as killed whole-cell vaccines. The FP sequence is highly conserved across coronaviruses; the six FP core amino acid residues, along with the four adjacent residues upstream and the three residues downstream from the core, are identical between SARS-CoV-2 and PEDV. We tested the efficacy of PEDV FP and SARS-CoV-2 FP vaccines in a PEDV challenge pig model. We demonstrated that both vaccines induced potent anamnestic responses upon virus challenge, potentiated interferon-γ responses, reduced viral RNA loads in jejunum tissue, and provided significant protection against clinical disease. However, neither vaccines elicited sterilizing immunity. Since SARS-CoV-2 FP and PEDV FP vaccines provided similar clinical protection, the coronavirus FP could be a target for a broadly protective vaccine using any platform. Importantly, the genome-reduced bacterial surface-expressed vaccine platform, when using a vaccine-appropriate bacterial vector, has potential utility as an inexpensive, readily manufactured, and rapid vaccine platform for other pathogens.
Published: 2021
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27. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Author: Klionsky, Daniel J., Abdel-aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie H., Abudu, Yakubu Princely, Acevedo-arozena, Abraham, Adamopoulos, Iannis E., Adeli, Khosrow, Adolph, Timon E., Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat B., Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed N., Agrotis, Alexander, Aguilar, Patricia V., Ahmad, S. Tariq, Ahmed, Zubair M., Ahumada-castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-abd, Ahmed M., Al-akra, Lina, Al-gharaibeh, Abeer, Alaoui-jamali, Moulay A., Alberti, Simon, Alcocer-gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-bari, M. Abdul, Aliwaini, Saeb, Alizadeh, Javad, Almacellas, Eugènia, Almasan, Alexandru, Alonso, Alicia, Alonso, Guillermo D., Altan-bonnet, Nihal, Altieri, Dario C., Álvarez, Élida M. C., Alves, Sara, Alves Da Costa, Cristine, Alzaharna, Mazen M., Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal O., Ammanathan, Veena, An, Zhenyi, Andersen, Stig U., Andrabi, Shaida A., Andrade-silva, Magaiver, Andres, Allen M., Angelini, Sabrina, Ann, David, Anozie, Uche C., Ansari, Mohammad Y., Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner L., Araya, Jun, Arden, Catherine, Arévalo, Maria-angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen R., Armstrong-james, Darius, Arnauné-pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela S., Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-fabian, Osnat, Atanasov, Atanas G., Au, Alicia K., Auberger, Patrick, Auner, Holger W., Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Ávalos, Yenniffer, Aveic, Sanja, Aveleira, Célia Alexandra, Avin-wittenberg, Tamar, Aydin, Yucel, Ayton, Scott, Ayyadevara, Srinivas, Azzopardi, Maria, Baba, Misuzu, Backer, Jonathan M., Backues, Steven K., Bae, Dong-hun, Bae, Ok-nam, Bae, Soo Han, Baehrecke, Eric H., Baek, Ahruem, Baek, Seung-hoon, Baek, Sung Hee, Bagetta, Giacinto, Bagniewska-zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xiyuan, Bai, Yidong, Bairagi, Nandadulal, Baksi, Shounak, Balbi, Teresa, Baldari, Cosima T., Balduini, Walter, Ballabio, Andrea, Ballester, Maria, Balazadeh, Salma, Balzan, Rena, Bandopadhyay, Rina, Banerjee, Sreeparna, Banerjee, Sulagna, Bánréti, Ágnes, Bao, Yan, Baptista, Mauricio S., Baracca, Alessandra, Barbati, Cristiana, Bargiela, Ariadna, Barilà, Daniela, Barlow, Peter G., Barmada, Sami J., Barreiro, Esther, Barreto, George E., Bartek, Jiri, Bartel, Bonnie, Bartolome, Alberto, Barve, Gaurav R., Basagoudanavar, Suresh H., Bassham, Diane C., Bast, Robert C., Basu, Alakananda, Batoko, Henri, Batten, Isabella, Baulieu, Etienne E., Baumgarner, Bradley L., Bayry, Jagadeesh, Beale, Rupert, Beau, Isabelle, Beaumatin, Florian, Bechara, Luiz R.g., Beck, George R., Beers, Michael F., Begun, Jakob, Behrends, Christian, Behrens, Georg M.n., Bei, Roberto, Bejarano, Eloy, Bel, Shai, Behl, Christian, Belaid, Amine, Belgareh-touzé, Naïma, Bellarosa, Cristina, Belleudi, Francesca, Belló Pérez, Melissa, Bello-morales, Raquel, Beltran, Jackeline Soares De Oliveira, Beltran, Sebastián, Benbrook, Doris Mangiaracina, Bendorius, Mykolas, Benitez, Bruno A., Benito-cuesta, Irene, Bensalem, Julien, Berchtold, Martin W., Berezowska, Sabina, Bergamaschi, Daniele, Bergami, Matteo, Bergmann, Andreas, Berliocchi, Laura, Berlioz-torrent, Clarisse, Bernard, Amélie, Berthoux, Lionel, Besirli, Cagri G., Besteiro, Sebastien, Betin, Virginie M., Beyaert, Rudi, Bezbradica, Jelena S., Bhaskar, Kiran, Bhatia-kissova, Ingrid, Bhattacharya, Resham, Bhattacharya, Sujoy, Bhattacharyya, Shalmoli, Bhuiyan, Md. Shenuarin, Bhutia, Sujit Kumar, Bi, Lanrong, Bi, Xiaolin, Biden, Trevor J., Bijian, Krikor, Billes, Viktor A., Binart, Nadine, Bincoletto, Claudia, Birgisdottir, Asa B., Bjorkoy, Geir, Blanco, Gonzalo, Blas-garcia, Ana, Blasiak, Janusz, Blomgran, Robert, Blomgren, Klas, Blum, Janice S., Boada-romero, Emilio, Boban, Mirta, Boesze-battaglia, Kathleen, Boeuf, Philippe, Boland, Barry, Bomont, Pascale, Bonaldo, Paolo, Bonam, Srinivasa Reddy, Bonfili, Laura, Bonifacino, Juan S., Boone, Brian A., Bootman, Martin D., Bordi, Matteo, Borner, Christoph, Bornhauser, Beat C., Borthakur, Gautam, Bosch, Jürgen, Bose, Santanu, Botana, Luis M., Botas, Juan, Boulanger, Chantal M., Boulton, Michael E., Bourdenx, Mathieu, Bourgeois, Benjamin, Bourke, Nollaig M., Bousquet, Guilhem, Boya, Patricia, Bozhkov, Peter V., Bozi, Luiz H. M., Bozkurt, Tolga O., Brackney, Doug E., Brandts, Christian H., Braun, Ralf J., Braus, Gerhard H., Bravo-sagua, Roberto, Bravo-san Pedro, José M., Brest, Patrick, Bringer, Marie-agnès, Briones-herrera, Alfredo, Broaddus, V. Courtney, Brodersen, Peter, Brodsky, Jeffrey L., Brody, Steven L., Bronson, Paola G., Bronstein, Jeff M., Brown, Carolyn N., Brown, Rhoderick E., Brum, Patricia C., Brumell, John H., Brunetti-pierri, Nicola, Bruno, Daniele, Bryson-richardson, Robert J., Bucci, Cecilia, Buchrieser, Carmen, Bueno, Marta, Buitrago-molina, Laura Elisa, Buraschi, Simone, Buch, Shilpa, Buchan, J. Ross, Buckingham, Erin M., Budak, Hikmet, Budini, Mauricio, Bultynck, Geert, Burada, Florin, Burgoyne, Joseph R., Burón, M. Isabel, Bustos, Victor, Büttner, Sabrina, Butturini, Elena, Byrd, Aaron, Cabas, Isabel, Cabrera-benitez, Sandra, Cadwell, Ken, Cai, Jingjing, Cai, Lu, Cai, Qian, Cairó, Montserrat, Calbet, Jose A., Caldwell, Guy A., Caldwell, Kim A., Call, Jarrod A., Calvani, Riccardo, Calvo, Ana C., Calvo-rubio Barrera, Miguel, Camara, Niels Os, Camonis, Jacques H., Camougrand, Nadine, Campanella, Michelangelo, Campbell, Edward M., Campbell-valois, François-xavier, Campello, Silvia, Campesi, Ilaria, Campos, Juliane C., Camuzard, Olivier, Cancino, Jorge, Candido De Almeida, Danilo, Canesi, Laura, Caniggia, Isabella, Canonico, Barbara, Cantí, Carles, Cao, Bin, Caraglia, Michele, Caramés, Beatriz, Carchman, Evie H., Cardenal-muñoz, Elena, Cardenas, Cesar, Cardenas, Luis, Cardoso, Sandra M., Carew, Jennifer S., Carle, Georges F., Carleton, Gillian, Carloni, Silvia, Carmona-gutierrez, Didac, Carneiro, Leticia A., Carnevali, Oliana, Carosi, Julian M., Carra, Serena, Carrier, Alice, Carrier, Lucie, Carroll, Bernadette, Carter, A. Brent, Carvalho, Andreia Neves, Casanova, Magali, Casas, Caty, Casas, Josefina, Cassioli, Chiara, Castillo, Eliseo F., Castillo, Karen, Castillo-lluva, Sonia, Castoldi, Francesca, Castori, Marco, Castro, Ariel F., Castro-caldas, Margarida, Castro-hernandez, Javier, Castro-obregon, Susana, Catz, Sergio D., Cavadas, Claudia, Cavaliere, Federica, Cavallini, Gabriella, Cavinato, Maria, Cayuela, Maria L., Cebollada Rica, Paula, Cecarini, Valentina, Cecconi, Francesco, Cechowska-pasko, Marzanna, Cenci, Simone, Ceperuelo-mallafré, Victòria, Cerqueira, João J., Cerutti, Janete M., Cervia, Davide, Cetintas, Vildan Bozok, Cetrullo, Silvia, Chae, Han-jung, Chagin, Andrei S., Chai, Chee-yin, Chakrabarti, Gopal, Chakrabarti, Oishee, Chakraborty, Tapas, Chakraborty, Trinad, Chami, Mounia, Chamilos, Georgios, Chan, David W., Chan, Edmond Y. W., Chan, Edward D., Chan, H.y. Edwin, Chan, Helen H., Chan, Hung, Chan, Matthew T.v., Chan, Yau Sang, Chandra, Partha K., Chang, Chih-peng, Chang, Chunmei, Chang, Hao-chun, Chang, Kai, Chao, Jie, Chapman, Tracey, Charlet-berguerand, Nicolas, Chatterjee, Samrat, Chaube, Shail K., Chaudhary, Anu, Chauhan, Santosh, Chaum, Edward, Checler, Frédéric, Cheetham, Michael E., Chen, Chang-shi, Chen, Guang-chao, Chen, Jian-fu, Chen, Liam L., Chen, Leilei, Chen, Lin, Chen, Mingliang, Chen, Mu-kuan, Chen, Ning, Chen, Quan, Chen, Ruey-hwa, Chen, Shi, Chen, Wei, Chen, Weiqiang, Chen, Xin-ming, Chen, Xiong-wen, Chen, Xu, Chen, Yan, Chen, Ye-guang, Chen, Yingyu, Chen, Yongqiang, Chen, Yu-jen, Chen, Yue-qin, Chen, Zhefan Stephen, Chen, Zhi, Chen, Zhi-hua, Chen, Zhijian J., Chen, Zhixiang, Cheng, Hanhua, Cheng, Jun, Cheng, Shi-yuan, Cheng, Wei, Cheng, Xiaodong, Cheng, Xiu-tang, Cheng, Yiyun, Cheng, Zhiyong, Chen, Zhong, Cheong, Heesun, Cheong, Jit Kong, Chernyak, Boris V., Cherry, Sara, Cheung, Chi Fai Randy, Cheung, Chun Hei Antonio, Cheung, King-ho, Chevet, Eric, Chi, Richard J., Chiang, Alan Kwok Shing, Chiaradonna, Ferdinando, Chiarelli, Roberto, Chiariello, Mario, Chica, Nathalia, Chiocca, Susanna, Chiong, Mario, Chiou, Shih-hwa, Chiramel, Abhilash I., Chiurchiù, Valerio, Cho, Dong-hyung, Choe, Seong-kyu, Choi, Augustine M.k., Choi, Mary E., Choudhury, Kamalika Roy, Chow, Norman S., Chu, Charleen T., Chua, Jason P., Chua, John Jia En, Chung, Hyewon, Chung, Kin Pan, Chung, Seockhoon, Chung, So-hyang, Chung, Yuen-li, Cianfanelli, Valentina, Ciechomska, Iwona A., Cifuentes, Mariana, Cinque, Laura, Cirak, Sebahattin, Cirone, Mara, Clague, Michael J., Clarke, Robert, Clementi, Emilio, Coccia, Eliana M., Codogno, Patrice, Cohen, Ehud, Cohen, Mickael M., Colasanti, Tania, Colasuonno, Fiorella, Colbert, Robert A., Colell, Anna, Čolić, Miodrag, Coll, Nuria S., Collins, Mark O., Colombo, María I., Colón-ramos, Daniel A., Combaret, Lydie, Comincini, Sergio, Cominetti, Márcia R., Consiglio, Antonella, Conte, Andrea, Conti, Fabrizio, Contu, Viorica Raluca, Cookson, Mark R., Coombs, Kevin M., Coppens, Isabelle, Corasaniti, Maria Tiziana, Corkery, Dale P., Cordes, Nils, Cortese, Katia, Costa, Maria Do Carmo, Costantino, Sarah, Costelli, Paola, Coto-montes, Ana, Crack, Peter J., Crespo, Jose L., Criollo, Alfredo, Crippa, Valeria, Cristofani, Riccardo, Csizmadia, Tamas, Cuadrado, Antonio, Cui, Bing, Cui, Jun, Cui, Yixian, Cui, Yong, Culetto, Emmanuel, Cumino, Andrea C., Cybulsky, Andrey V., Czaja, Mark J., Czuczwar, Stanislaw J., D’adamo, Stefania, D’amelio, Marcello, D’arcangelo, Daniela, D’lugos, Andrew C., D’orazi, Gabriella, Da Silva, James A., Dafsari, Hormos Salimi, Dagda, Ruben K., Dagdas, Yasin, Daglia, Maria, Dai, Xiaoxia, Dai, Yun, Dai, Yuyuan, Dal Col, Jessica, Dalhaimer, Paul, Dalla Valle, Luisa, Dallenga, Tobias, Dalmasso, Guillaume, Damme, Markus, Dando, Ilaria, Dantuma, Nico P., Darling, April L., Das, Hiranmoy, Dasarathy, Srinivasan, Dasari, Santosh K., Dash, Srikanta, Daumke, Oliver, Dauphinee, Adrian N., Davies, Jeffrey S., Dávila, Valeria A., Davis, Roger J., Davis, Tanja, Dayalan Naidu, Sharadha, De Amicis, Francesca, De Bosscher, Karolien, De Felice, Francesca, De Franceschi, Lucia, De Leonibus, Chiara, De Mattos Barbosa, Mayara G., De Meyer, Guido R.y., De Milito, Angelo, De Nunzio, Cosimo, De Palma, Clara, De Santi, Mauro, De Virgilio, Claudio, De Zio, Daniela, Debnath, Jayanta, Debosch, Brian J., Decuypere, Jean-paul, Deehan, Mark A., Deflorian, Gianluca, Degregori, James, Dehay, Benjamin, Del Rio, Gabriel, Delaney, Joe R., Delbridge, Lea M. D., Delorme-axford, Elizabeth, Delpino, M. Victoria, Demarchi, Francesca, Dembitz, Vilma, Demers, Nicholas D., Deng, Hongbin, Deng, Zhiqiang, Dengjel, Joern, Dent, Paul, Denton, Donna, Depamphilis, Melvin L., Der, Channing J., Deretic, Vojo, Descoteaux, Albert, Devis, Laura, Devkota, Sushil, Devuyst, Olivier, Dewson, Grant, Dharmasivam, Mahendiran, Dhiman, Rohan, Di Bernardo, Diego, Di Cristina, Manlio, Di Domenico, Fabio, Di Fazio, Pietro, Di Fonzo, Alessio, Di Guardo, Giovanni, Di Guglielmo, Gianni M., Di Leo, Luca, Di Malta, Chiara, Di Nardo, Alessia, Di Rienzo, Martina, Di Sano, Federica, Diallinas, George, Diao, Jiajie, Diaz-araya, Guillermo, Díaz-laviada, Inés, Dickinson, Jared M., Diederich, Marc, Dieudé, Mélanie, Dikic, Ivan, Ding, Shiping, Ding, Wen-xing, Dini, Luciana, Dinić, Jelena, Dinic, Miroslav, Dinkova-kostova, Albena T., Dionne, Marc S., Distler, Jörg H.w., Diwan, Abhinav, Dixon, Ian M.c., Djavaheri-mergny, Mojgan, Dobrinski, Ina, Dobrovinskaya, Oxana, Dobrowolski, Radek, Dobson, Renwick C.j., Đokić, Jelena, Dokmeci Emre, Serap, Donadelli, Massimo, Dong, Bo, Dong, Xiaonan, Dong, Zhiwu, Dorn Ii, Gerald W., Dotsch, Volker, Dou, Huan, Dou, Juan, Dowaidar, Moataz, Dridi, Sami, Drucker, Liat, Du, Ailian, Du, Caigan, Du, Guangwei, Du, Hai-ning, Du, Li-lin, Du Toit, André, Duan, Shao-bin, Duan, Xiaoqiong, Duarte, Sónia P., Dubrovska, Anna, Dunlop, Elaine A., Dupont, Nicolas, Durán, Raúl V., Dwarakanath, Bilikere S., Dyshlovoy, Sergey A., Ebrahimi-fakhari, Darius, Eckhart, Leopold, Edelstein, Charles L., Efferth, Thomas, Eftekharpour, Eftekhar, Eichinger, Ludwig, Eid, Nabil, Eisenberg, Tobias, Eissa, N. Tony, Eissa, Sanaa, Ejarque, Miriam, El Andaloussi, Abdeljabar, El-hage, Nazira, El-naggar, Shahenda, Eleuteri, Anna Maria, El-shafey, Eman S., Elgendy, Mohamed, Eliopoulos, Aristides G., Elizalde, María M., Elks, Philip M., Elsasser, Hans-peter, Elsherbiny, Eslam S., Emerling, Brooke M., Emre, N. C. Tolga, Eng, Christina H., Engedal, Nikolai, Engelbrecht, Anna-mart, Engelsen, Agnete S.t., Enserink, Jorrit M., Escalante, Ricardo, Esclatine, Audrey, Escobar-henriques, Mafalda, Eskelinen, Eeva-liisa, Espert, Lucile, Eusebio, Makandjou-ola, Fabrias, Gemma, Fabrizi, Cinzia, Facchiano, Antonio, Facchiano, Francesco, Fadeel, Bengt, Fader, Claudio, Faesen, Alex C., Fairlie, W. 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R., Lane, Jon D., Lang, Charles H., Lange, Carsten, Langel, Ülo, Langer, Rupert, Lapaquette, Pierre, Laporte, Jocelyn, Larusso, Nicholas F., Lastres-becker, Isabel, Lau, Wilson Chun Yu, Laurie, Gordon W., Lavandero, Sergio, Law, Betty Yuen Kwan, Law, Helen Ka-wai, Layfield, Rob, Le, Weidong, Le Stunff, Herve, Leary, Alexandre Y., Lebrun, Jean-jacques, Leck, Lionel Y.w., Leduc-gaudet, Jean-philippe, Lee, Changwook, Lee, Chung-pei, Lee, Da-hye, Lee, Edward B., Lee, Erinna F., Lee, Gyun Min, Lee, He-jin, Lee, Heung Kyu, Lee, Jae Man, Lee, Jason S., Lee, Jin-a, Lee, Joo-yong, Lee, Jun Hee, Lee, Michael, Lee, Min Goo, Lee, Min Jae, Lee, Myung-shik, Lee, Sang Yoon, Lee, Seung-jae, Lee, Stella Y., Lee, Sung Bae, Lee, Won Hee, Lee, Ying-ray, Lee, Yong-ho, Lee, Youngil, Lefebvre, Christophe, Legouis, Renaud, Lei, Yu L., Lei, Yuchen, Leikin, Sergey, Leitinger, Gerd, Lemus, Leticia, Leng, Shuilong, Lenoir, Olivia, Lenz, Guido, Lenz, Heinz Josef, Lenzi, Paola, León, Yolanda, Leopoldino, Andréia M., Leschczyk, Christoph, Leskelä, Stina, Letellier, Elisabeth, Leung, Chi-ting, Leung, Po Sing, Leventhal, Jeremy S., Levine, Beth, Lewis, Patrick A., Ley, Klaus, Li, Bin, Li, Da-qiang, Li, Jianming, Li, Jing, Li, Jiong, Li, Ke, Li, Liwu, Li, Mei, Li, Min, Li, Ming, Li, Mingchuan, Li, Pin-lan, Li, Ming-qing, Li, Qing, Li, Sheng, Li, Tiangang, Li, Wei, Li, Wenming, Li, Xue, Li, Yi-ping, Li, Yuan, Li, Zhiqiang, Li, Zhiyong, Li, Zhiyuan, Lian, Jiqin, Liang, Chengyu, Liang, Qiangrong, Liang, Weicheng, Liang, Yongheng, Liang, Yongtian, Liao, Guanghong, Liao, Lujian, Liao, Mingzhi, Liao, Yung-feng, Librizzi, Mariangela, Lie, Pearl P. Y., Lilly, Mary A., Lim, Hyunjung J., Lima, Thania R.r., Limana, Federica, Lin, Chao, Lin, Chih-wen, Lin, Dar-shong, Lin, Fu-cheng, Lin, Jiandie D., Lin, Kurt M., Lin, Kwang-huei, Lin, Liang-tzung, Lin, Pei-hui, Lin, Qiong, Lin, Shaofeng, Lin, Su-ju, Lin, Wenyu, Lin, Xueying, Lin, Yao-xin, Lin, Yee-shin, Linden, Rafael, Lindner, Paula, Ling, Shuo-chien, Lingor, Paul, Linnemann, Amelia K., Liou, Yih-cherng, Lipinski, Marta M., Lipovšek, Saška, Lira, Vitor A., Lisiak, Natalia, Liton, Paloma B., Liu, Chao, Liu, Ching-hsuan, Liu, Chun-feng, Liu, Cui Hua, Liu, Fang, Liu, Hao, Liu, Hsiao-sheng, Liu, Hua-feng, Liu, Huifang, Liu, Jia, Liu, Jing, Liu, Julia, Liu, Leyuan, Liu, Longhua, Liu, Meilian, Liu, Qin, Liu, Wei, Liu, Wende, Liu, Xiao-hong, Liu, Xiaodong, Liu, Xingguo, Liu, Xu, Liu, Xuedong, Liu, Yanfen, Liu, Yang, Liu, Yueyang, Liu, Yule, Livingston, J. Andrew, Lizard, Gerard, Lizcano, Jose M., Ljubojevic-holzer, Senka, Lleonart, Matilde E., Llobet-navàs, David, Llorente, Alicia, Lo, Chih Hung, Lobato-márquez, Damián, Long, Qi, Long, Yun Chau, Loos, Ben, Loos, Julia A., López, Manuela G., López-doménech, Guillermo, López-guerrero, José Antonio, López-jiménez, Ana T., López-pérez, Óscar, López-valero, Israel, Lorenowicz, Magdalena J., Lorente, Mar, Lorincz, Peter, Lossi, Laura, Lotersztajn, Sophie, Lovat, Penny E., Lovell, Jonathan F., Lovy, Alenka, Lőw, Péter, Lu, Guang, Lu, Haocheng, Lu, Jia-hong, Lu, Jin-jian, Lu, Mengji, Lu, Shuyan, Luciani, Alessandro, Lucocq, John M., Ludovico, Paula, Luftig, Micah A., Luhr, Morten, Luis-ravelo, Diego, Lum, Julian J., Luna-dulcey, Liany, Lund, Anders H., Lund, Viktor K., Lünemann, Jan D., Lüningschrör, Patrick, Luo, Honglin, Luo, Rongcan, Luo, Shouqing, Luo, Zhi, Luparello, Claudio, Lüscher, Bernhard, Luu, Luan, Lyakhovich, Alex, Lyamzaev, Konstantin G., Lystad, Alf Håkon, Lytvynchuk, Lyubomyr, Ma, Alvin C., Ma, Changle, Ma, Mengxiao, Ma, Ning-fang, Ma, Quan-hong, Ma, Xinliang, Ma, Yueyun, Ma, Zhenyi, Macdougald, Ormond A., Macian, Fernando, Macintosh, Gustavo C., Mackeigan, Jeffrey P., Macleod, Kay F., Maday, Sandra, Madeo, Frank, Madesh, Muniswamy, Madl, Tobias, Madrigal-matute, Julio, Maeda, Akiko, Maejima, Yasuhiro, Magarinos, Marta, Mahavadi, Poornima, Maiani, Emiliano, Maiese, Kenneth, Maiti, Panchanan, Maiuri, Maria Chiara, Majello, Barbara, Major, Michael B., Makareeva, Elena, Malik, Fayaz, Mallilankaraman, Karthik, Malorni, Walter, Maloyan, Alina, Mammadova, Najiba, Man, Gene Chi Wai, Manai, Federico, Mancias, Joseph D., Mandelkow, Eva-maria, Mandell, Michael A., Manfredi, Angelo A., Manjili, Masoud H., Manjithaya, Ravi, Manque, Patricio, Manshian, Bella B., Manzano, Raquel, Manzoni, Claudia, Mao, Kai, Marchese, Cinzia, Marchetti, Sandrine, Marconi, Anna Maria, Marcucci, Fabrizio, Mardente, Stefania, Mareninova, Olga A., Margeta, Marta, Mari, Muriel, Marinelli, Sara, Marinelli, Oliviero, Mariño, Guillermo, Mariotto, Sofia, Marshall, Richard S., Marten, Mark R., Martens, Sascha, Martin, Alexandre P.j., Martin, Katie R., Martin, Sara, Martin, Shaun, Martín-segura, Adrián, Martín-acebes, Miguel A., Martin-burriel, Inmaculada, Martin-rincon, Marcos, Martin-sanz, Paloma, Martina, José A., Martinet, Wim, Martinez, Aitor, Martinez, Ana, Martinez, Jennifer, Martinez Velazquez, Moises, Martinez-lopez, Nuria, Martinez-vicente, Marta, Martins, Daniel O., Martins, Joilson O., Martins, Waleska K., Martins-marques, Tania, Marzetti, Emanuele, Masaldan, Shashank, Masclaux-daubresse, Celine, Mashek, Douglas G., Massa, Valentina, Massieu, Lourdes, Masson, Glenn R., Masuelli, Laura, Masyuk, Anatoliy I., Masyuk, Tetyana V., Matarrese, Paola, Matheu, Ander, Matoba, Satoaki, Matsuzaki, Sachiko, Mattar, Pamela, Matte, Alessandro, Mattoscio, Domenico, Mauriz, José L., Mauthe, Mario, Mauvezin, Caroline, Maverakis, Emanual, Maycotte, Paola, Mayer, Johanna, Mazzoccoli, Gianluigi, Mazzoni, Cristina, Mazzulli, Joseph R., Mccarty, Nami, Mcdonald, Christine, Mcgill, Mitchell R., Mckenna, Sharon L., Mclaughlin, Bethann, Mcloughlin, Fionn, Mcniven, Mark A., Mcwilliams, Thomas G., Mechta-grigoriou, Fatima, Medeiros, Tania Catarina, Medina, Diego L., Megeney, Lynn A., Megyeri, Klara, Mehrpour, Maryam, Mehta, Jawahar L., Meijer, Alfred J., Meijer, Annemarie H., Mejlvang, Jakob, Meléndez, Alicia, Melk, Annette, Memisoglu, Gonen, Mendes, Alexandrina F., Meng, Delong, Meng, Fei, Meng, Tian, Menna-barreto, Rubem, Menon, Manoj B., Mercer, Carol, Mercier, Anne E., Mergny, Jean-louis, Merighi, Adalberto, Merkley, Seth D., Merla, Giuseppe, Meske, Volker, Mestre, Ana Cecilia, Metur, Shree Padma, Meyer, Christian, Meyer, Hemmo, Mi, Wenyi, Mialet-perez, Jeanne, Miao, Junying, Micale, Lucia, Miki, Yasuo, Milan, Enrico, Milczarek, Małgorzata, Miller, Dana L., Miller, Samuel I., Miller, Silke, Millward, Steven W., Milosevic, Ira, Minina, Elena A., Mirzaei, Hamed, Mirzaei, Hamid Reza, Mirzaei, Mehdi, Mishra, Amit, Mishra, Nandita, Mishra, Paras Kumar, Misirkic Marjanovic, Maja, Misasi, Roberta, Misra, Amit, Misso, Gabriella, Mitchell, Claire, Mitou, Geraldine, Miura, Tetsuji, Miyamoto, Shigeki, Miyazaki, Makoto, Miyazaki, Mitsunori, Miyazaki, Taiga, Miyazawa, Keisuke, Mizushima, Noboru, Mogensen, Trine H., Mograbi, Baharia, Mohammadinejad, Reza, Mohamud, Yasir, Mohanty, Abhishek, Mohapatra, Sipra, Möhlmann, Torsten, Mohmmed, Asif, Moles, Anna, Moley, Kelle H., Molinari, Maurizio, Mollace, Vincenzo, Møller, Andreas Buch, Mollereau, Bertrand, Mollinedo, Faustino, Montagna, Costanza, Monteiro, Mervyn J., Montella, Andrea, Montes, L. 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Patrick, Murthy, Aditya, Myöhänen, Timo T., Mysorekar, Indira U., Mytych, Jennifer, Nabavi, Seyed Mohammad, Nabissi, Massimo, Nagy, Péter, Nah, Jihoon, Nahimana, Aimable, Nakagawa, Ichiro, Nakamura, Ken, Nakatogawa, Hitoshi, Nandi, Shyam S., Nanjundan, Meera, Nanni, Monica, Napolitano, Gennaro, Nardacci, Roberta, Narita, Masashi, Nassif, Melissa, Nathan, Ilana, Natsumeda, Manabu, Naude, Ryno J., Naumann, Christin, Naveiras, Olaia, Navid, Fatemeh, Nawrocki, Steffan T., Nazarko, Taras Y., Nazio, Francesca, Negoita, Florentina, Neill, Thomas, Neisch, Amanda L., Neri, Luca M., Netea, Mihai G., Neubert, Patrick, Neufeld, Thomas P., Neumann, Dietbert, Neutzner, Albert, Newton, Phillip T., Ney, Paul A., Nezis, Ioannis P., Ng, Charlene C.w., Ng, Tzi Bun, Nguyen, Hang T. T., Nguyen, Long T., Ni, Hong-min, Ní Cheallaigh, Clíona, Ni, Zhenhong, Nicolao, M. Celeste, Nicoli, Francesco, Nieto-diaz, Manuel, Nilsson, Per, Ning, Shunbin, Niranjan, Rituraj, Nishimune, Hiroshi, Niso-santano, Mireia, Nixon, Ralph A., Nobili, Annalisa, Nobrega, Clevio, Noda, Takeshi, Nogueira-recalde, Uxía, Nolan, Trevor M., Nombela, Ivan, Novak, Ivana, Novoa, Beatriz, Nozawa, Takashi, Nukina, Nobuyuki, Nussbaum-krammer, Carmen, Nylandsted, Jesper, O’donovan, Tracey R., O’leary, Seónadh M., O’rourke, Eyleen J., O’sullivan, Mary P., O’sullivan, Timothy E., Oddo, Salvatore, Oehme, Ina, Ogawa, Michinaga, Ogier-denis, Eric, Ogmundsdottir, Margret H., Ogretmen, Besim, Oh, Goo Taeg, Oh, Seon-hee, Oh, Young J., Ohama, Takashi, Ohashi, Yohei, Ohmuraya, Masaki, Oikonomou, Vasileios, Ojha, Rani, Okamoto, Koji, Okazawa, Hitoshi, Oku, Masahide, Oliván, Sara, Oliveira, Jorge M. A., Ollmann, Michael, Olzmann, James A., Omari, Shakib, Omary, M. Bishr, Önal, Gizem, Ondrej, Martin, Ong, Sang-bing, Ong, Sang-ging, Onnis, Anna, Orellana, Juan A., Orellana-muñoz, Sara, Ortega-villaizan, Maria Del Mar, Ortiz-gonzalez, Xilma R., Ortona, Elena, Osiewacz, Heinz D., Osman, Abdel-hamid K., Osta, Rosario, Otegui, Marisa S., Otsu, Kinya, Ott, Christiane, Ottobrini, Luisa, Ou, Jing-hsiung James, Outeiro, Tiago F., Oynebraten, Inger, Ozturk, Melek, Pagès, Gilles, Pahari, Susanta, Pajares, Marta, Pajvani, Utpal B., Pal, Rituraj, Paladino, Simona, Pallet, Nicolas, Palmieri, Michela, Palmisano, Giuseppe, Palumbo, Camilla, Pampaloni, Francesco, Pan, Lifeng, Pan, Qingjun, Pan, Wenliang, Pan, Xin, Panasyuk, Ganna, Pandey, Rahul, Pandey, Udai B., Pandya, Vrajesh, Paneni, Francesco, Pang, Shirley Y., Panzarini, Elisa, Papademetrio, Daniela L., Papaleo, Elena, Papinski, Daniel, Papp, Diana, Park, Eun Chan, Park, Hwan Tae, Park, Ji-man, Park, Jong-in, Park, Joon Tae, Park, Junsoo, Park, Sang Chul, Park, Sang-youel, Parola, Abraham H., Parys, Jan B., Pasquier, Adrien, Pasquier, Benoit, Passos, João F., Pastore, Nunzia, Patel, Hemal H., Patschan, Daniel, Pattingre, Sophie, Pedraza-alva, Gustavo, Pedraza-chaverri, Jose, Pedrozo, Zully, Pei, Gang, Pei, Jianming, Peled-zehavi, Hadas, Pellegrini, Joaquín M., Pelletier, Joffrey, Peñalva, Miguel A., Peng, Di, Peng, Ying, Penna, Fabio, Pennuto, Maria, Pentimalli, Francesca, Pereira, Cláudia Mf, Pereira, Gustavo J.s., Pereira, Lilian C., Pereira De Almeida, Luis, Perera, Nirma D., Pérez-lara, Ángel, Perez-oliva, Ana B., Pérez-pérez, María Esther, Periyasamy, Palsamy, Perl, Andras, Perrotta, Cristiana, Perrotta, Ida, Pestell, Richard G., Petersen, Morten, Petrache, Irina, Petrovski, Goran, Pfirrmann, Thorsten, Pfister, Astrid S., Philips, Jennifer A., Pi, Huifeng, Picca, Anna, Pickrell, Alicia M., Picot, Sandy, Pierantoni, Giovanna M., Pierdominici, Marina, Pierre, Philippe, Pierrefite-carle, Valérie, Pierzynowska, Karolina, Pietrocola, Federico, Pietruczuk, Miroslawa, Pignata, Claudio, Pimentel-muiños, Felipe X., Pinar, Mario, Pinheiro, Roberta O., Pinkas-kramarski, Ronit, Pinton, Paolo, Pircs, Karolina, Piya, Sujan, Pizzo, Paola, Plantinga, Theo S., Platta, Harald W., Plaza-zabala, Ainhoa, Plomann, Markus, Plotnikov, Egor Y., Plun-favreau, Helene, Pluta, Ryszard, Pocock, Roger, Pöggeler, Stefanie, Pohl, Christian, Poirot, Marc, Poletti, Angelo, Ponpuak, Marisa, Popelka, Hana, Popova, Blagovesta, Porta, Helena, Porte Alcon, Soledad, Portilla-fernandez, Eliana, Post, Martin, Potts, Malia B., Poulton, Joanna, Powers, Ted, Prahlad, Veena, Prajsnar, Tomasz K., Praticò, Domenico, Prencipe, Rosaria, Priault, Muriel, Proikas-cezanne, Tassula, Promponas, Vasilis J., Proud, Christopher G., Puertollano, Rosa, Puglielli, Luigi, Pulinilkunnil, Thomas, Puri, Deepika, Puri, Rajat, Puyal, Julien, Qi, Xiaopeng, Qi, Yongmei, Qian, Wenbin, Qiang, Lei, Qiu, Yu, Quadrilatero, Joe, Quarleri, Jorge, Raben, Nina, Rabinowich, Hannah, Ragona, Debora, Ragusa, Michael J., Rahimi, Nader, Rahmati, Marveh, Raia, Valeria, Raimundo, Nuno, Rajasekaran, Namakkal-soorappan, Ramachandra Rao, Sriganesh, Rami, Abdelhaq, Ramírez-pardo, Ignacio, Ramsden, David B., Randow, Felix, Rangarajan, Pundi N., Ranieri, Danilo, Rao, Hai, Rao, Lang, Rao, Rekha, Rathore, Sumit, Ratnayaka, J. Arjuna, Ratovitski, Edward A., Ravanan, Palaniyandi, Ravegnini, Gloria, Ray, Swapan K., Razani, Babak, Rebecca, Vito, Reggiori, Fulvio, Régnier-vigouroux, Anne, Reichert, Andreas S., Reigada, David, Reiling, Jan H., Rein, Theo, Reipert, Siegfried, Rekha, Rokeya Sultana, Ren, Hongmei, Ren, Jun, Ren, Weichao, Renault, Tristan, Renga, Giorgia, Reue, Karen, Rewitz, Kim, Ribeiro De Andrade Ramos, Bruna, Riazuddin, S. Amer, Ribeiro-rodrigues, Teresa M., Ricci, Jean-ehrland, Ricci, Romeo, Riccio, Victoria, Richardson, Des R., Rikihisa, Yasuko, Risbud, Makarand V., Risueño, Ruth M., Ritis, Konstantinos, Rizza, Salvatore, Rizzuto, Rosario, Roberts, Helen C., Roberts, Luke D., Robinson, Katherine J., Roccheri, Maria Carmela, Rocchi, Stephane, Rodney, George G., Rodrigues, Tiago, Rodrigues Silva, Vagner Ramon, Rodriguez, Amaia, Rodriguez-barrueco, Ruth, Rodriguez-henche, Nieves, Rodriguez-rocha, Humberto, Roelofs, Jeroen, Rogers, Robert S., Rogov, Vladimir V., Rojo, Ana I., Rolka, Krzysztof, Romanello, Vanina, Romani, Luigina, Romano, Alessandra, Romano, Patricia S., Romeo-guitart, David, Romero, Luis C., Romero, Montserrat, Roney, Joseph C., Rongo, Christopher, Roperto, Sante, Rosenfeldt, Mathias T., Rosenstiel, Philip, Rosenwald, Anne G., Roth, Kevin A., Roth, Lynn, Roth, Steven, Rouschop, Kasper M.a., Roussel, Benoit D., Roux, Sophie, Rovere-querini, Patrizia, Roy, Ajit, Rozieres, Aurore, Ruano, Diego, Rubinsztein, David C., Rubtsova, Maria P., Ruckdeschel, Klaus, Ruckenstuhl, Christoph, Rudolf, Emil, Rudolf, Rüdiger, Ruggieri, Alessandra, Ruparelia, Avnika Ashok, Rusmini, Paola, Russell, Ryan R., Russo, Gian Luigi, Russo, Maria, Russo, Rossella, Ryabaya, Oxana O., Ryan, Kevin M., Ryu, Kwon-yul, Sabater-arcis, Maria, Sachdev, Ulka, Sacher, Michael, Sachse, Carsten, Sadhu, Abhishek, Sadoshima, Junichi, Safren, Nathaniel, Saftig, Paul, Sagona, Antonia P., Sahay, Gaurav, Sahebkar, Amirhossein, Sahin, Mustafa, Sahin, Ozgur, Sahni, Sumit, Saito, Nayuta, Saito, Shigeru, Saito, Tsunenori, Sakai, Ryohei, Sakai, Yasuyoshi, Sakamaki, Jun-ichi, Saksela, Kalle, Salazar, Gloria, Salazar-degracia, Anna, Salekdeh, Ghasem H., Saluja, Ashok K., Sampaio-marques, Belém, Sanchez, Maria Cecilia, Sanchez-alcazar, Jose A., Sanchez-vera, Victoria, Sancho-shimizu, Vanessa, Sanderson, J. Thomas, Sandri, Marco, Santaguida, Stefano, Santambrogio, Laura, Santana, Magda M., Santoni, Giorgio, Sanz, Alberto, Sanz, Pascual, Saran, Shweta, Sardiello, Marco, Sargeant, Timothy J., Sarin, Apurva, Sarkar, Chinmoy, Sarkar, Sovan, Sarrias, Maria-rosa, Sarkar, Surajit, Sarmah, Dipanka Tanu, Sarparanta, Jaakko, Sathyanarayan, Aishwarya, Sathyanarayanan, Ranganayaki, Scaglione, K. Matthew, Scatozza, Francesca, Schaefer, Liliana, Schafer, Zachary T., Schaible, Ulrich E., Schapira, Anthony H.v., Scharl, Michael, Schatzl, Hermann M., Schein, Catherine H., Scheper, Wiep, Scheuring, David, Schiaffino, Maria Vittoria, Schiappacassi, Monica, Schindl, Rainer, Schlattner, Uwe, Schmidt, Oliver, Schmitt, Roland, Schmidt, Stephen D., Schmitz, Ingo, Schmukler, Eran, Schneider, Anja, Schneider, Bianca E., Schober, Romana, Schoijet, Alejandra C., Schott, Micah B., Schramm, Michael, Schröder, Bernd, Schuh, Kai, Schüller, Christoph, Schulze, Ryan J., Schürmanns, Lea, Schwamborn, Jens C., Schwarten, Melanie, Scialo, Filippo, Sciarretta, Sebastiano, Scott, Melanie J., Scotto, Kathleen W., Scovassi, A. Ivana, Scrima, Andrea, Scrivo, Aurora, Sebastian, David, Sebti, Salwa, Sedej, Simon, Segatori, Laura, Segev, Nava, Seglen, Per O., Seiliez, Iban, Seki, Ekihiro, Selleck, Scott B., Sellke, Frank W., Selsby, Joshua T., Sendtner, Michael, Senturk, Serif, Seranova, Elena, Sergi, Consolato, Serra-moreno, Ruth, Sesaki, Hiromi, Settembre, Carmine, Setty, Subba Rao Gangi, Sgarbi, Gianluca, Sha, Ou, Shacka, John J., Shah, Javeed A., Shang, Dantong, Shao, Changshun, Shao, Feng, Sharbati, Soroush, Sharkey, Lisa M., Sharma, Dipali, Sharma, Gaurav, Sharma, Kulbhushan, Sharma, Pawan, Sharma, Surendra, Shen, Han-ming, Shen, Hongtao, Shen, Jiangang, Shen, Ming, Shen, Weili, Shen, Zheni, Sheng, Rui, Sheng, Zhi, Sheng, Zu-hang, Shi, Jianjian, Shi, Xiaobing, Shi, Ying-hong, Shiba-fukushima, Kahori, Shieh, Jeng-jer, Shimada, Yohta, Shimizu, Shigeomi, Shimozawa, Makoto, Shintani, Takahiro, Shoemaker, Christopher J., Shojaei, Shahla, Shoji, Ikuo, Shravage, Bhupendra V., Shridhar, Viji, Shu, Chih-wen, Shu, Hong-bing, Shui, Ke, Shukla, Arvind K., Shutt, Timothy E., Sica, Valentina, Siddiqui, Aleem, Sierra, Amanda, Sierra-torre, Virginia, Signorelli, Santiago, Sil, Payel, Silva, Bruno J. 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M., St. Clair, Daret, Stagni, Venturina, Staiano, Leopoldo, Stalnecker, Clint A., Stankov, Metodi V., Stathopulos, Peter B., Stefan, Katja, Stefan, Sven Marcel, Stefanis, Leonidas, Steffan, Joan S., Steinkasserer, Alexander, Stenmark, Harald, Sterneckert, Jared, Stevens, Craig, Stoka, Veronika, Storch, Stephan, Stork, Björn, Strappazzon, Flavie, Strohecker, Anne Marie, Stupack, Dwayne G., Su, Huanxing, Su, Ling-yan, Su, Longxiang, Suarez-fontes, Ana M., Subauste, Carlos S., Subbian, Selvakumar, Subirada, Paula V., Sudhandiran, Ganapasam, Sue, Carolyn M., Sui, Xinbing, Summers, Corey, Sun, Guangchao, Sun, Jun, Sun, Kang, Sun, Meng-xiang, Sun, Qiming, Sun, Yi, Sun, Zhongjie, Sunahara, Karen K.s., Sundberg, Eva, Susztak, Katalin, Sutovsky, Peter, Suzuki, Hidekazu, Sweeney, Gary, Symons, J. David, Sze, Stephen Cho Wing, Szewczyk, Nathaniel J., Tabęcka-łonczynska, Anna, Tabolacci, Claudio, Tacke, Frank, Taegtmeyer, Heinrich, Tafani, Marco, Tagaya, Mitsuo, Tai, Haoran, Tait, Stephen W. G., Takahashi, Yoshinori, Takats, Szabolcs, Talwar, Priti, Tam, Chit, Tam, Shing Yau, Tampellini, Davide, Tamura, Atsushi, Tan, Chong Teik, Tan, Eng-king, Tan, Ya-qin, Tanaka, Masaki, Tanaka, Motomasa, Tang, Daolin, Tang, Jingfeng, Tang, Tie-shan, Tanida, Isei, Tao, Zhipeng, Taouis, Mohammed, Tatenhorst, Lars, Tavernarakis, Nektarios, Taylor, Allen, Taylor, Gregory A., Taylor, Joan M., Tchetina, Elena, Tee, Andrew R., Tegeder, Irmgard, Teis, David, Teixeira, Natercia, Teixeira-clerc, Fatima, Tekirdag, Kumsal A., Tencomnao, Tewin, Tenreiro, Sandra, Tepikin, Alexei V., Testillano, Pilar S., Tettamanti, Gianluca, Tharaux, Pierre-louis, Thedieck, Kathrin, Thekkinghat, Arvind A., Thellung, Stefano, Thinwa, Josephine W., Thirumalaikumar, V.p., Thomas, Sufi Mary, Thomes, Paul G., Thorburn, Andrew, Thukral, Lipi, Thum, Thomas, Thumm, Michael, Tian, Ling, Tichy, Ales, Till, Andreas, Timmerman, Vincent, Titorenko, Vladimir I., Todi, Sokol V., Todorova, Krassimira, Toivonen, Janne M., Tomaipitinca, Luana, Tomar, Dhanendra, Tomas-zapico, Cristina, Tomić, Sergej, Tong, Benjamin Chun-kit, Tong, Chao, Tong, Xin, Tooze, Sharon A., Torgersen, Maria L., Torii, Satoru, Torres-lópez, Liliana, Torriglia, Alicia, Towers, Christina G., Towns, Roberto, Toyokuni, Shinya, Trajkovic, Vladimir, Tramontano, Donatella, Tran, Quynh-giao, Travassos, Leonardo H., Trelford, Charles B., Tremel, Shirley, Trougakos, Ioannis P., Tsao, Betty P., Tschan, Mario P., Tse, Hung-fat, Tse, Tak Fu, Tsugawa, Hitoshi, Tsvetkov, Andrey S., Tumbarello, David A., Tumtas, Yasin, Tuñón, María J., Turcotte, Sandra, Turk, Boris, Turk, Vito, Turner, Bradley J., Tuxworth, Richard I., Tyler, Jessica K., Tyutereva, Elena V., Uchiyama, Yasuo, Ugun-klusek, Aslihan, Uhlig, Holm H., Ułamek-kozioł, Marzena, Ulasov, Ilya V., Umekawa, Midori, Ungermann, Christian, Unno, Rei, Urbe, Sylvie, Uribe-carretero, Elisabet, Üstün, Suayib, Uversky, Vladimir N, Vaccari, Thomas, Vaccaro, Maria I., Vahsen, Björn F., Vakifahmetoglu-norberg, Helin, Valdor, Rut, Valente, Maria J., Valko, Ayelén, Vallee, Richard B., Valverde, Angela M., Van Den Berghe, Greet, Van Der Veen, Stijn, Van Kaer, Luc, Van Loosdregt, Jorg, Van Wijk, Sjoerd J.l., Vandenberghe, Wim, Vanhorebeek, Ilse, Vannier-santos, Marcos A., Vannini, Nicola, Vanrell, M. Cristina, Vantaggiato, Chiara, Varano, Gabriele, Varela-nieto, Isabel, Varga, Máté, Vasconcelos, M. 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Haung, Yu, Zhengping, Yu, Zhou, Yuan, Junying, Yuan, Ling-qing, Yuan, Shilin, Yuan, Shyng-shiou F., Yuan, Yanggang, Yuan, Zengqiang, Yue, Jianbo, Yue, Zhenyu, Yun, Jeanho, Yung, Raymond L., Zacks, David N., Zaffagnini, Gabriele, Zambelli, Vanessa O., Zanella, Isabella, Zang, Qun S., Zanivan, Sara, Zappavigna, Silvia, Zaragoza, Pilar, Zarbalis, Konstantinos S., Zarebkohan, Amir, Zarrouk, Amira, Zeitlin, Scott O., Zeng, Jialiu, Zeng, Ju-deng, Žerovnik, Eva, Zhan, Lixuan, Zhang, Bin, Zhang, Donna D., Zhang, Hanlin, Zhang, Hong, Zhang, Honghe, Zhang, Huafeng, Zhang, Huaye, Zhang, Hui, Zhang, Hui-ling, Zhang, Jianbin, Zhang, Jianhua, Zhang, Jing-pu, Zhang, Kalin Y.b., Zhang, Leshuai W., Zhang, Lin, Zhang, Lisheng, Zhang, Lu, Zhang, Luoying, Zhang, Menghuan, Zhang, Peng, Zhang, Sheng, Zhang, Wei, Zhang, Xiangnan, Zhang, Xiao-wei, Zhang, Xiaolei, Zhang, Xiaoyan, Zhang, Xin, Zhang, Xinxin, Zhang, Xu Dong, Zhang, Yang, Zhang, Yanjin, Zhang, Yi, Zhang, Ying-dong, Zhang, Yingmei, Zhang, Yuan-yuan, Zhang, Yuchen, Zhang, Zhe, Zhang, Zhengguang, Zhang, Zhibing, Zhang, Zhihai, Zhang, Zhiyong, Zhang, Zili, Zhao, Haobin, Zhao, Lei, Zhao, Shuang, Zhao, Tongbiao, Zhao, Xiao-fan, Zhao, Ying, Zhao, Yongchao, Zhao, Yongliang, Zhao, Yuting, Zheng, Guoping, Zheng, Kai, Zheng, Ling, Zheng, Shizhong, Zheng, Xi-long, Zheng, Yi, Zheng, Zu-guo, Zhivotovsky, Boris, Zhong, Qing, Zhou, Ao, Zhou, Ben, Zhou, Cefan, Zhou, Gang, Zhou, Hao, Zhou, Hong, Zhou, Hongbo, Zhou, Jie, Zhou, Jing, Zhou, Jiyong, Zhou, Kailiang, Zhou, Rongjia, Zhou, Xu-jie, Zhou, Yanshuang, Zhou, Yinghong, Zhou, Yubin, Zhou, Zheng-yu, Zhou, Zhou, Zhu, Binglin, Zhu, Changlian, Zhu, Guo-qing, Zhu, Haining, Zhu, Hongxin, Zhu, Hua, Zhu, Wei-guo, Zhu, Yanping, Zhu, Yushan, Zhuang, Haixia, Zhuang, Xiaohong, Zientara-rytter, Katarzyna, Zimmermann, Christine M., Ziviani, Elena, Zoladek, Teresa, Zong, Wei-xing, Zorov, Dmitry B., Zorzano, Antonio, Zou, Weiping, Zou, Zhen, Zou, Zhengzhi, Zuryn, Steven, Zwerschke, Werner, Brand-saberi, Beate, Dong, X. Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith C., Stallings, Christina L., Tong, Chun-kit, Klionsky, Daniel J., Abdel-aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie H., Abudu, Yakubu Princely, Acevedo-arozena, Abraham, Adamopoulos, Iannis E., Adeli, Khosrow, Adolph, Timon E., Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat B., Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed N., Agrotis, Alexander, Aguilar, Patricia V., Ahmad, S. Tariq, Ahmed, Zubair M., Ahumada-castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-abd, Ahmed M., Al-akra, Lina, Al-gharaibeh, Abeer, Alaoui-jamali, Moulay A., Alberti, Simon, Alcocer-gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-bari, M. 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C., Alves, Sara, Alves Da Costa, Cristine, Alzaharna, Mazen M., Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal O., Ammanathan, Veena, An, Zhenyi, Andersen, Stig U., Andrabi, Shaida A., Andrade-silva, Magaiver, Andres, Allen M., Angelini, Sabrina, Ann, David, Anozie, Uche C., Ansari, Mohammad Y., Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner L., Araya, Jun, Arden, Catherine, Arévalo, Maria-angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen R., Armstrong-james, Darius, Arnauné-pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela S., Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-fabian, Osnat, Atanasov, Atanas G., Au, Alicia K., Auberger, Patrick, Auner, Holger W., Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Ávalos, Yenniffer, Aveic, Sanja, Aveleira, Célia Alexandra, Avin-wittenberg, Tamar, Aydin, Yucel, Ayton, Scott, Ayyadevara, Srinivas, Azzopardi, Maria, Baba, Misuzu, Backer, Jonathan M., Backues, Steven K., Bae, Dong-hun, Bae, Ok-nam, Bae, Soo Han, Baehrecke, Eric H., Baek, Ahruem, Baek, Seung-hoon, Baek, Sung Hee, Bagetta, Giacinto, Bagniewska-zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xiyuan, Bai, Yidong, Bairagi, Nandadulal, Baksi, Shounak, Balbi, Teresa, Baldari, Cosima T., Balduini, Walter, Ballabio, Andrea, Ballester, Maria, Balazadeh, Salma, Balzan, Rena, Bandopadhyay, Rina, Banerjee, Sreeparna, Banerjee, Sulagna, Bánréti, Ágnes, Bao, Yan, Baptista, Mauricio S., Baracca, Alessandra, Barbati, Cristiana, Bargiela, Ariadna, Barilà, Daniela, Barlow, Peter G., Barmada, Sami J., Barreiro, Esther, Barreto, George E., Bartek, Jiri, Bartel, Bonnie, Bartolome, Alberto, Barve, Gaurav R., Basagoudanavar, Suresh H., Bassham, Diane C., Bast, Robert C., Basu, Alakananda, Batoko, Henri, Batten, Isabella, Baulieu, Etienne E., Baumgarner, Bradley L., Bayry, Jagadeesh, Beale, Rupert, Beau, Isabelle, Beaumatin, Florian, Bechara, Luiz R.g., Beck, George R., Beers, Michael F., Begun, Jakob, Behrends, Christian, Behrens, Georg M.n., Bei, Roberto, Bejarano, Eloy, Bel, Shai, Behl, Christian, Belaid, Amine, Belgareh-touzé, Naïma, Bellarosa, Cristina, Belleudi, Francesca, Belló Pérez, Melissa, Bello-morales, Raquel, Beltran, Jackeline Soares De Oliveira, Beltran, Sebastián, Benbrook, Doris Mangiaracina, Bendorius, Mykolas, Benitez, Bruno A., Benito-cuesta, Irene, Bensalem, Julien, Berchtold, Martin W., Berezowska, Sabina, Bergamaschi, Daniele, Bergami, Matteo, Bergmann, Andreas, Berliocchi, Laura, Berlioz-torrent, Clarisse, Bernard, Amélie, Berthoux, Lionel, Besirli, Cagri G., Besteiro, Sebastien, Betin, Virginie M., Beyaert, Rudi, Bezbradica, Jelena S., Bhaskar, Kiran, Bhatia-kissova, Ingrid, Bhattacharya, Resham, Bhattacharya, Sujoy, Bhattacharyya, Shalmoli, Bhuiyan, Md. Shenuarin, Bhutia, Sujit Kumar, Bi, Lanrong, Bi, Xiaolin, Biden, Trevor J., Bijian, Krikor, Billes, Viktor A., Binart, Nadine, Bincoletto, Claudia, Birgisdottir, Asa B., Bjorkoy, Geir, Blanco, Gonzalo, Blas-garcia, Ana, Blasiak, Janusz, Blomgran, Robert, Blomgren, Klas, Blum, Janice S., Boada-romero, Emilio, Boban, Mirta, Boesze-battaglia, Kathleen, Boeuf, Philippe, Boland, Barry, Bomont, Pascale, Bonaldo, Paolo, Bonam, Srinivasa Reddy, Bonfili, Laura, Bonifacino, Juan S., Boone, Brian A., Bootman, Martin D., Bordi, Matteo, Borner, Christoph, Bornhauser, Beat C., Borthakur, Gautam, Bosch, Jürgen, Bose, Santanu, Botana, Luis M., Botas, Juan, Boulanger, Chantal M., Boulton, Michael E., Bourdenx, Mathieu, Bourgeois, Benjamin, Bourke, Nollaig M., Bousquet, Guilhem, Boya, Patricia, Bozhkov, Peter V., Bozi, Luiz H. M., Bozkurt, Tolga O., Brackney, Doug E., Brandts, Christian H., Braun, Ralf J., Braus, Gerhard H., Bravo-sagua, Roberto, Bravo-san Pedro, José M., Brest, Patrick, Bringer, Marie-agnès, Briones-herrera, Alfredo, Broaddus, V. Courtney, Brodersen, Peter, Brodsky, Jeffrey L., Brody, Steven L., Bronson, Paola G., Bronstein, Jeff M., Brown, Carolyn N., Brown, Rhoderick E., Brum, Patricia C., Brumell, John H., Brunetti-pierri, Nicola, Bruno, Daniele, Bryson-richardson, Robert J., Bucci, Cecilia, Buchrieser, Carmen, Bueno, Marta, Buitrago-molina, Laura Elisa, Buraschi, Simone, Buch, Shilpa, Buchan, J. Ross, Buckingham, Erin M., Budak, Hikmet, Budini, Mauricio, Bultynck, Geert, Burada, Florin, Burgoyne, Joseph R., Burón, M. Isabel, Bustos, Victor, Büttner, Sabrina, Butturini, Elena, Byrd, Aaron, Cabas, Isabel, Cabrera-benitez, Sandra, Cadwell, Ken, Cai, Jingjing, Cai, Lu, Cai, Qian, Cairó, Montserrat, Calbet, Jose A., Caldwell, Guy A., Caldwell, Kim A., Call, Jarrod A., Calvani, Riccardo, Calvo, Ana C., Calvo-rubio Barrera, Miguel, Camara, Niels Os, Camonis, Jacques H., Camougrand, Nadine, Campanella, Michelangelo, Campbell, Edward M., Campbell-valois, François-xavier, Campello, Silvia, Campesi, Ilaria, Campos, Juliane C., Camuzard, Olivier, Cancino, Jorge, Candido De Almeida, Danilo, Canesi, Laura, Caniggia, Isabella, Canonico, Barbara, Cantí, Carles, Cao, Bin, Caraglia, Michele, Caramés, Beatriz, Carchman, Evie H., Cardenal-muñoz, Elena, Cardenas, Cesar, Cardenas, Luis, Cardoso, Sandra M., Carew, Jennifer S., Carle, Georges F., Carleton, Gillian, Carloni, Silvia, Carmona-gutierrez, Didac, Carneiro, Leticia A., Carnevali, Oliana, Carosi, Julian M., Carra, Serena, Carrier, Alice, Carrier, Lucie, Carroll, Bernadette, Carter, A. Brent, Carvalho, Andreia Neves, Casanova, Magali, Casas, Caty, Casas, Josefina, Cassioli, Chiara, Castillo, Eliseo F., Castillo, Karen, Castillo-lluva, Sonia, Castoldi, Francesca, Castori, Marco, Castro, Ariel F., Castro-caldas, Margarida, Castro-hernandez, Javier, Castro-obregon, Susana, Catz, Sergio D., Cavadas, Claudia, Cavaliere, Federica, Cavallini, Gabriella, Cavinato, Maria, Cayuela, Maria L., Cebollada Rica, Paula, Cecarini, Valentina, Cecconi, Francesco, Cechowska-pasko, Marzanna, Cenci, Simone, Ceperuelo-mallafré, Victòria, Cerqueira, João J., Cerutti, Janete M., Cervia, Davide, Cetintas, Vildan Bozok, Cetrullo, Silvia, Chae, Han-jung, Chagin, Andrei S., Chai, Chee-yin, Chakrabarti, Gopal, Chakrabarti, Oishee, Chakraborty, Tapas, Chakraborty, Trinad, Chami, Mounia, Chamilos, Georgios, Chan, David W., Chan, Edmond Y. W., Chan, Edward D., Chan, H.y. Edwin, Chan, Helen H., Chan, Hung, Chan, Matthew T.v., Chan, Yau Sang, Chandra, Partha K., Chang, Chih-peng, Chang, Chunmei, Chang, Hao-chun, Chang, Kai, Chao, Jie, Chapman, Tracey, Charlet-berguerand, Nicolas, Chatterjee, Samrat, Chaube, Shail K., Chaudhary, Anu, Chauhan, Santosh, Chaum, Edward, Checler, Frédéric, Cheetham, Michael E., Chen, Chang-shi, Chen, Guang-chao, Chen, Jian-fu, Chen, Liam L., Chen, Leilei, Chen, Lin, Chen, Mingliang, Chen, Mu-kuan, Chen, Ning, Chen, Quan, Chen, Ruey-hwa, Chen, Shi, Chen, Wei, Chen, Weiqiang, Chen, Xin-ming, Chen, Xiong-wen, Chen, Xu, Chen, Yan, Chen, Ye-guang, Chen, Yingyu, Chen, Yongqiang, Chen, Yu-jen, Chen, Yue-qin, Chen, Zhefan Stephen, Chen, Zhi, Chen, Zhi-hua, Chen, Zhijian J., Chen, Zhixiang, Cheng, Hanhua, Cheng, Jun, Cheng, Shi-yuan, Cheng, Wei, Cheng, Xiaodong, Cheng, Xiu-tang, Cheng, Yiyun, Cheng, Zhiyong, Chen, Zhong, Cheong, Heesun, Cheong, Jit Kong, Chernyak, Boris V., Cherry, Sara, Cheung, Chi Fai Randy, Cheung, Chun Hei Antonio, Cheung, King-ho, Chevet, Eric, Chi, Richard J., Chiang, Alan Kwok Shing, Chiaradonna, Ferdinando, Chiarelli, Roberto, Chiariello, Mario, Chica, Nathalia, Chiocca, Susanna, Chiong, Mario, Chiou, Shih-hwa, Chiramel, Abhilash I., Chiurchiù, Valerio, Cho, Dong-hyung, Choe, Seong-kyu, Choi, Augustine M.k., Choi, Mary E., Choudhury, Kamalika Roy, Chow, Norman S., Chu, Charleen T., Chua, Jason P., Chua, John Jia En, Chung, Hyewon, Chung, Kin Pan, Chung, Seockhoon, Chung, So-hyang, Chung, Yuen-li, Cianfanelli, Valentina, Ciechomska, Iwona A., Cifuentes, Mariana, Cinque, Laura, Cirak, Sebahattin, Cirone, Mara, Clague, Michael J., Clarke, Robert, Clementi, Emilio, Coccia, Eliana M., Codogno, Patrice, Cohen, Ehud, Cohen, Mickael M., Colasanti, Tania, Colasuonno, Fiorella, Colbert, Robert A., Colell, Anna, Čolić, Miodrag, Coll, Nuria S., Collins, Mark O., Colombo, María I., Colón-ramos, Daniel A., Combaret, Lydie, Comincini, Sergio, Cominetti, Márcia R., Consiglio, Antonella, Conte, Andrea, Conti, Fabrizio, Contu, Viorica Raluca, Cookson, Mark R., Coombs, Kevin M., Coppens, Isabelle, Corasaniti, Maria Tiziana, Corkery, Dale P., Cordes, Nils, Cortese, Katia, Costa, Maria Do Carmo, Costantino, Sarah, Costelli, Paola, Coto-montes, Ana, Crack, Peter J., Crespo, Jose L., Criollo, Alfredo, Crippa, Valeria, Cristofani, Riccardo, Csizmadia, Tamas, Cuadrado, Antonio, Cui, Bing, Cui, Jun, Cui, Yixian, Cui, Yong, Culetto, Emmanuel, Cumino, Andrea C., Cybulsky, Andrey V., Czaja, Mark J., Czuczwar, Stanislaw J., D’adamo, Stefania, D’amelio, Marcello, D’arcangelo, Daniela, D’lugos, Andrew C., D’orazi, Gabriella, Da Silva, James A., Dafsari, Hormos Salimi, Dagda, Ruben K., Dagdas, Yasin, Daglia, Maria, Dai, Xiaoxia, Dai, Yun, Dai, Yuyuan, Dal Col, Jessica, Dalhaimer, Paul, Dalla Valle, Luisa, Dallenga, Tobias, Dalmasso, Guillaume, Damme, Markus, Dando, Ilaria, Dantuma, Nico P., Darling, April L., Das, Hiranmoy, Dasarathy, Srinivasan, Dasari, Santosh K., Dash, Srikanta, Daumke, Oliver, Dauphinee, Adrian N., Davies, Jeffrey S., Dávila, Valeria A., Davis, Roger J., Davis, Tanja, Dayalan Naidu, Sharadha, De Amicis, Francesca, De Bosscher, Karolien, De Felice, Francesca, De Franceschi, Lucia, De Leonibus, Chiara, De Mattos Barbosa, Mayara G., De Meyer, Guido R.y., De Milito, Angelo, De Nunzio, Cosimo, De Palma, Clara, De Santi, Mauro, De Virgilio, Claudio, De Zio, Daniela, Debnath, Jayanta, Debosch, Brian J., Decuypere, Jean-paul, Deehan, Mark A., Deflorian, Gianluca, Degregori, James, Dehay, Benjamin, Del Rio, Gabriel, Delaney, Joe R., Delbridge, Lea M. D., Delorme-axford, Elizabeth, Delpino, M. Victoria, Demarchi, Francesca, Dembitz, Vilma, Demers, Nicholas D., Deng, Hongbin, Deng, Zhiqiang, Dengjel, Joern, Dent, Paul, Denton, Donna, Depamphilis, Melvin L., Der, Channing J., Deretic, Vojo, Descoteaux, Albert, Devis, Laura, Devkota, Sushil, Devuyst, Olivier, Dewson, Grant, Dharmasivam, Mahendiran, Dhiman, Rohan, Di Bernardo, Diego, Di Cristina, Manlio, Di Domenico, Fabio, Di Fazio, Pietro, Di Fonzo, Alessio, Di Guardo, Giovanni, Di Guglielmo, Gianni M., Di Leo, Luca, Di Malta, Chiara, Di Nardo, Alessia, Di Rienzo, Martina, Di Sano, Federica, Diallinas, George, Diao, Jiajie, Diaz-araya, Guillermo, Díaz-laviada, Inés, Dickinson, Jared M., Diederich, Marc, Dieudé, Mélanie, Dikic, Ivan, Ding, Shiping, Ding, Wen-xing, Dini, Luciana, Dinić, Jelena, Dinic, Miroslav, Dinkova-kostova, Albena T., Dionne, Marc S., Distler, Jörg H.w., Diwan, Abhinav, Dixon, Ian M.c., Djavaheri-mergny, Mojgan, Dobrinski, Ina, Dobrovinskaya, Oxana, Dobrowolski, Radek, Dobson, Renwick C.j., Đokić, Jelena, Dokmeci Emre, Serap, Donadelli, Massimo, Dong, Bo, Dong, Xiaonan, Dong, Zhiwu, Dorn Ii, Gerald W., Dotsch, Volker, Dou, Huan, Dou, Juan, Dowaidar, Moataz, Dridi, Sami, Drucker, Liat, Du, Ailian, Du, Caigan, Du, Guangwei, Du, Hai-ning, Du, Li-lin, Du Toit, André, Duan, Shao-bin, Duan, Xiaoqiong, Duarte, Sónia P., Dubrovska, Anna, Dunlop, Elaine A., Dupont, Nicolas, Durán, Raúl V., Dwarakanath, Bilikere S., Dyshlovoy, Sergey A., Ebrahimi-fakhari, Darius, Eckhart, Leopold, Edelstein, Charles L., Efferth, Thomas, Eftekharpour, Eftekhar, Eichinger, Ludwig, Eid, Nabil, Eisenberg, Tobias, Eissa, N. Tony, Eissa, Sanaa, Ejarque, Miriam, El Andaloussi, Abdeljabar, El-hage, Nazira, El-naggar, Shahenda, Eleuteri, Anna Maria, El-shafey, Eman S., Elgendy, Mohamed, Eliopoulos, Aristides G., Elizalde, María M., Elks, Philip M., Elsasser, Hans-peter, Elsherbiny, Eslam S., Emerling, Brooke M., Emre, N. C. Tolga, Eng, Christina H., Engedal, Nikolai, Engelbrecht, Anna-mart, Engelsen, Agnete S.t., Enserink, Jorrit M., Escalante, Ricardo, Esclatine, Audrey, Escobar-henriques, Mafalda, Eskelinen, Eeva-liisa, Espert, Lucile, Eusebio, Makandjou-ola, Fabrias, Gemma, Fabrizi, Cinzia, Facchiano, Antonio, Facchiano, Francesco, Fadeel, Bengt, Fader, Claudio, Faesen, Alex C., Fairlie, W. Douglas, Falcó, Alberto, Falkenburger, Bjorn H., Fan, Daping, Fan, Jie, Fan, Yanbo, Fang, Evandro F., Fang, Yanshan, Fang, Yognqi, Fanto, Manolis, Farfel-becker, Tamar, Faure, Mathias, Fazeli, Gholamreza, Fedele, Anthony O., Feldman, Arthur M., Feng, Du, Feng, Jiachun, Feng, Lifeng, Feng, Yibin, Feng, Yuchen, Feng, Wei, Fenz Araujo, Thais, Ferguson, Thomas A., Fernández, Álvaro F., Fernandez-checa, Jose C., Fernández-veledo, Sonia, Fernie, Alisdair R., Ferrante, Anthony W., Ferraresi, Alessandra, Ferrari, Merari F., Ferreira, Julio C.b., Ferro-novick, Susan, Figueras, Antonio, Filadi, Riccardo, Filigheddu, Nicoletta, Filippi-chiela, Eduardo, Filomeni, Giuseppe, Fimia, Gian Maria, Fineschi, Vittorio, Finetti, Francesca, Finkbeiner, Steven, Fisher, Edward A., Fisher, Paul B., Flamigni, Flavio, Fliesler, Steven J., Flo, Trude H., Florance, Ida, Florey, Oliver, Florio, Tullio, Fodor, Erika, Follo, Carlo, Fon, Edward A., Forlino, Antonella, Fornai, Francesco, Fortini, Paola, Fracassi, Anna, Fraldi, Alessandro, Franco, Brunella, Franco, Rodrigo, Franconi, Flavia, Frankel, Lisa B., Friedman, Scott L., Fröhlich, Leopold F., Frühbeck, Gema, Fuentes, Jose M., Fujiki, Yukio, Fujita, Naonobu, Fujiwara, Yuuki, Fukuda, Mitsunori, Fulda, Simone, Furic, Luc, Furuya, Norihiko, Fusco, Carmela, Gack, Michaela U., Gaffke, Lidia, Galadari, Sehamuddin, Galasso, Alessia, Galindo, Maria F., Gallolu Kankanamalage, Sachith, Galluzzi, Lorenzo, Galy, Vincent, Gammoh, Noor, Gan, Boyi, Ganley, Ian G., Gao, Feng, Gao, Hui, Gao, Minghui, Gao, Ping, Gao, Shou-jiang, Gao, Wentao, Gao, Xiaobo, Garcera, Ana, Garcia, Maria Noé, Garcia, Verónica E., García-del Portillo, Francisco, Garcia-escudero, Vega, Garcia-garcia, Aracely, Garcia-macia, Marina, García-moreno, Diana, Garcia-ruiz, Carmen, García-sanz, Patricia, Garg, Abhishek D., Gargini, Ricardo, Garofalo, Tina, Garry, Robert F., Gassen, Nils C., Gatica, Damian, Ge, Liang, Ge, Wanzhong, Geiss-friedlander, Ruth, Gelfi, Cecilia, Genschik, Pascal, Gentle, Ian E., Gerbino, Valeria, Gerhardt, Christoph, Germain, Kyla, Germain, Marc, Gewirtz, David A., Ghasemipour Afshar, Elham, Ghavami, Saeid, Ghigo, Alessandra, Ghosh, Manosij, Giamas, Georgios, Giampietri, Claudia, Giatromanolaki, Alexandra, Gibson, Gary E., Gibson, Spencer B., Ginet, Vanessa, Giniger, Edward, Giorgi, Carlotta, Girao, Henrique, Girardin, Stephen E., Giridharan, Mridhula, Giuliano, Sandy, Giulivi, Cecilia, Giuriato, Sylvie, Giustiniani, Julien, Gluschko, Alexander, Goder, Veit, Goginashvili, Alexander, Golab, Jakub, Goldstone, David C., Golebiewska, Anna, Gomes, Luciana R., Gomez, Rodrigo, Gómez-sánchez, Rubén, Gomez-puerto, Maria Catalina, Gomez-sintes, Raquel, Gong, Qingqiu, Goni, Felix M., González-gallego, Javier, Gonzalez-hernandez, Tomas, Gonzalez-polo, Rosa A., Gonzalez-reyes, Jose A., González-rodríguez, Patricia, Goping, Ing Swie, Gorbatyuk, Marina S., Gorbunov, Nikolai V., Görgülü, Kıvanç, Gorojod, Roxana M., Gorski, Sharon M., Goruppi, Sandro, Gotor, Cecilia, Gottlieb, Roberta A., Gozes, Illana, Gozuacik, Devrim, Graef, Martin, Gräler, Markus H., Granatiero, Veronica, Grasso, Daniel, Gray, Joshua P., Green, Douglas R., Greenhough, Alexander, Gregory, Stephen L., Griffin, Edward F., Grinstaff, Mark W., Gros, Frederic, Grose, Charles, Gross, Angelina S., Gruber, Florian, Grumati, Paolo, Grune, Tilman, Gu, Xueyan, Guan, Jun-lin, Guardia, Carlos M., Guda, Kishore, Guerra, Flora, Guerri, Consuelo, Guha, Prasun, Guillén, Carlos, Gujar, Shashi, Gukovskaya, Anna, Gukovsky, Ilya, Gunst, Jan, Günther, Andreas, Guntur, Anyonya R., Guo, Chuanyong, Guo, Chun, Guo, Hongqing, Guo, Lian-wang, Guo, Ming, Gupta, Pawan, Gupta, Shashi Kumar, Gupta, Swapnil, Gupta, Veer Bala, Gupta, Vivek, Gustafsson, Asa B., Gutterman, David D., H.b., Ranjitha, Haapasalo, Annakaisa, Haber, James E., Hać, Aleksandra, Hadano, Shinji, Hafrén, Anders J., Haidar, Mansour, Hall, Belinda S., Halldén, Gunnel, Hamacher-brady, Anne, Hamann, Andrea, Hamasaki, Maho, Han, Weidong, Hansen, Malene, Hanson, Phyllis I., Hao, Zijian, Harada, Masaru, Harhaji-trajkovic, Ljubica, Hariharan, Nirmala, Haroon, Nigil, Harris, James, Hasegawa, Takafumi, Hasima Nagoor, Noor, Haspel, Jeffrey A., Haucke, Volker, Hawkins, Wayne D., Hay, Bruce A., Haynes, Cole M., Hayrabedyan, Soren B., Hays, Thomas S., He, Congcong, He, Qin, He, Rong-rong, He, You-wen, He, Yu-ying, Heakal, Yasser, Heberle, Alexander M., Hejtmancik, J. Fielding, Helgason, Gudmundur Vignir, Henkel, Vanessa, Herb, Marc, Hergovich, Alexander, Herman-antosiewicz, Anna, Hernández, Agustín, Hernandez, Carlos, Hernandez-diaz, Sergio, Hernandez-gea, Virginia, Herpin, Amaury, Herreros, Judit, Hervás, Javier H., Hesselson, Daniel, Hetz, Claudio, Heussler, Volker T., Higuchi, Yujiro, Hilfiker, Sabine, Hill, Joseph A., Hlavacek, William S., Ho, Emmanuel A., Ho, Idy H.t., Ho, Philip Wing-lok, Ho, Shu-leong, Ho, Wan Yun, Hobbs, G. Aaron, Hochstrasser, Mark, Hoet, Peter H.m., Hofius, Daniel, Hofman, Paul, Höhn, Annika, Holmberg, Carina I., Hombrebueno, Jose R., Yi-ren Hong, Chang-won Hong, Hooper, Lora V., Hoppe, Thorsten, Horos, Rastislav, Hoshida, Yujin, Hsin, I-lun, Hsu, Hsin-yun, Hu, Bing, Hu, Dong, Hu, Li-fang, Hu, Ming Chang, Hu, Ronggui, Hu, Wei, Hu, Yu-chen, Hu, Zhuo-wei, Hua, Fang, Hua, Jinlian, Hua, Yingqi, Huan, Chongmin, Huang, Canhua, Huang, Chuanshu, Huang, Chuanxin, Huang, Chunling, Huang, Haishan, Huang, Kun, Huang, Michael L.h., Huang, Rui, Huang, Shan, Huang, Tianzhi, Huang, Xing, Huang, Yuxiang Jack, Huber, Tobias B., Hubert, Virginie, Hubner, Christian A., Hughes, Stephanie M., Hughes, William E., Humbert, Magali, Hummer, Gerhard, Hurley, James H., Hussain, Sabah, Hussain, Salik, Hussey, Patrick J., Hutabarat, Martina, Hwang, Hui-yun, Hwang, Seungmin, Ieni, Antonio, Ikeda, Fumiyo, Imagawa, Yusuke, Imai, Yuzuru, Imbriano, Carol, Imoto, Masaya, Inman, Denise M., Inoki, Ken, Iovanna, Juan, Iozzo, Renato V., Ippolito, Giuseppe, Irazoqui, Javier E., Iribarren, Pablo, Ishaq, Mohd, Ishikawa, Makoto, Ishimwe, Nestor, Isidoro, Ciro, Ismail, Nahed, Issazadeh-navikas, Shohreh, Itakura, Eisuke, Ito, Daisuke, Ivankovic, Davor, Ivanova, Saška, Iyer, Anand Krishnan V., Izquierdo, José M., Izumi, Masanori, Jäättelä, Marja, Jabir, Majid Sakhi, Jackson, William T., Jacobo-herrera, Nadia, Jacomin, Anne-claire, Jacquin, Elise, Jadiya, Pooja, Jaeschke, Hartmut, Jagannath, Chinnaswamy, Jakobi, Arjen J., Jakobsson, Johan, Janji, Bassam, Jansen-dürr, Pidder, Jansson, Patric J., Jantsch, Jonathan, Januszewski, Sławomir, Jassey, Alagie, Jean, Steve, Jeltsch-david, Hélène, Jendelova, Pavla, Jenny, Andreas, Jensen, Thomas E., Jessen, Niels, Jewell, Jenna L., Ji, Jing, Jia, Lijun, Jia, Rui, Jiang, Liwen, Jiang, Qing, Jiang, Richeng, Jiang, Teng, Jiang, Xuejun, Jiang, Yu, Jimenez-sanchez, Maria, Jin, Eun-jung, Jin, Fengyan, Jin, Hongchuan, Jin, Li, Jin, Luqi, Jin, Meiyan, Jin, Si, Jo, Eun-kyeong, Joffre, Carine, Johansen, Terje, Johnson, Gail V.w., Johnston, Simon A., Jokitalo, Eija, Jolly, Mohit Kumar, Joosten, Leo A.b., Jordan, Joaquin, Joseph, Bertrand, Ju, Dianwen, Ju, Jeong-sun, Ju, Jingfang, Juárez, Esmeralda, Judith, Delphine, Juhász, Gábor, Jun, Youngsoo, Jung, Chang Hwa, Jung, Sung-chul, Jung, Yong Keun, Jungbluth, Heinz, Jungverdorben, Johannes, Just, Steffen, Kaarniranta, Kai, Kaasik, Allen, Kabuta, Tomohiro, Kaganovich, Daniel, Kahana, Alon, Kain, Renate, Kajimura, Shinjo, Kalamvoki, Maria, Kalia, Manjula, Kalinowski, Danuta S., Kaludercic, Nina, Kalvari, Ioanna, Kaminska, Joanna, Kaminskyy, Vitaliy O., Kanamori, Hiromitsu, Kanasaki, Keizo, Kang, Chanhee, Kang, Rui, Kang, Sang Sun, Kaniyappan, Senthilvelrajan, Kanki, Tomotake, Kanneganti, Thirumala-devi, Kanthasamy, Anumantha G., Kanthasamy, Arthi, Kantorow, Marc, Kapuy, Orsolya, Karamouzis, Michalis V., Karim, Md. Razaul, Karmakar, Parimal, Katare, Rajesh G., Kato, Masaru, Kaufmann, Stefan H.e., Kauppinen, Anu, Kaushal, Gur P., Kaushik, Susmita, Kawasaki, Kiyoshi, Kazan, Kemal, Ke, Po-yuan, Keating, Damien J., Keber, Ursula, Kehrl, John H., Keller, Kate E., Keller, Christian W., Kemper, Jongsook Kim, Kenific, Candia M., Kepp, Oliver, Kermorgant, Stephanie, Kern, Andreas, Ketteler, Robin, Keulers, Tom G., Khalfin, Boris, Khalil, Hany, Khambu, Bilon, Khan, Shahid Y., Khandelwal, Vinoth Kumar Megraj, Khandia, Rekha, Kho, Widuri, Khobrekar, Noopur V., Khuansuwan, Sataree, Khundadze, Mukhran, Killackey, Samuel A., Kim, Dasol, Kim, Deok Ryong, Kim, Do-hyung, Kim, Dong-eun, Kim, Eun Young, Kim, Eun-kyoung, Kim, Hak-rim, Kim, Hee-sik, Hyung-ryong Kim, Kim, Jeong Hun, Kim, Jin Kyung, Kim, Jin-hoi, Kim, Joungmok, Kim, Ju Hwan, Kim, Keun Il, Kim, Peter K., Kim, Seong-jun, Kimball, Scot R., Kimchi, Adi, Kimmelman, Alec C., Kimura, Tomonori, King, Matthew A., Kinghorn, Kerri J., Kinsey, Conan G., Kirkin, Vladimir, Kirshenbaum, Lorrie A., Kiselev, Sergey L., Kishi, Shuji, Kitamoto, Katsuhiko, Kitaoka, Yasushi, Kitazato, Kaio, Kitsis, Richard N., Kittler, Josef T., Kjaerulff, Ole, Klein, Peter S., Klopstock, Thomas, Klucken, Jochen, Knævelsrud, Helene, Knorr, Roland L., Ko, Ben C.b., Ko, Fred, Ko, Jiunn-liang, Kobayashi, Hotaka, Kobayashi, Satoru, Koch, Ina, Koch, Jan C., Koenig, Ulrich, Kögel, Donat, Koh, Young Ho, Koike, Masato, Kohlwein, Sepp D., Kocaturk, Nur M., Komatsu, Masaaki, König, Jeannette, Kono, Toru, Kopp, Benjamin T., Korcsmaros, Tamas, Korkmaz, Gözde, Korolchuk, Viktor I., Korsnes, Mónica Suárez, Koskela, Ali, Kota, Janaiah, Kotake, Yaichiro, Kotler, Monica L., Kou, Yanjun, Koukourakis, Michael I., Koustas, Evangelos, Kovacs, Attila L., Kovács, Tibor, Koya, Daisuke, Kozako, Tomohiro, Kraft, Claudine, Krainc, Dimitri, Krämer, Helmut, Krasnodembskaya, Anna D., Kretz-remy, Carole, Kroemer, Guido, Ktistakis, Nicholas T., Kuchitsu, Kazuyuki, Kuenen, Sabine, Kuerschner, Lars, Kukar, Thomas, Kumar, Ajay, Kumar, Ashok, Kumar, Deepak, Kumar, Dhiraj, Kumar, Sharad, Kume, Shinji, Kumsta, Caroline, Kundu, Chanakya N., Kundu, Mondira, Kunnumakkara, Ajaikumar B., Kurgan, Lukasz, Kutateladze, Tatiana G., Kutlu, Ozlem, Kwak, Seongae, Kwon, Ho Jeong, Kwon, Taeg Kyu, Kwon, Yong Tae, Kyrmizi, Irene, La Spada, Albert, Labonté, Patrick, Ladoire, Sylvain, Laface, Ilaria, Lafont, Frank, Lagace, Diane C., Lahiri, Vikramjit, Lai, Zhibing, Laird, Angela S., Lakkaraju, Aparna, Lamark, Trond, Lan, Sheng-hui, Landajuela, Ane, Lane, Darius J. R., Lane, Jon D., Lang, Charles H., Lange, Carsten, Langel, Ülo, Langer, Rupert, Lapaquette, Pierre, Laporte, Jocelyn, Larusso, Nicholas F., Lastres-becker, Isabel, Lau, Wilson Chun Yu, Laurie, Gordon W., Lavandero, Sergio, Law, Betty Yuen Kwan, Law, Helen Ka-wai, Layfield, Rob, Le, Weidong, Le Stunff, Herve, Leary, Alexandre Y., Lebrun, Jean-jacques, Leck, Lionel Y.w., Leduc-gaudet, Jean-philippe, Lee, Changwook, Lee, Chung-pei, Lee, Da-hye, Lee, Edward B., Lee, Erinna F., Lee, Gyun Min, Lee, He-jin, Lee, Heung Kyu, Lee, Jae Man, Lee, Jason S., Lee, Jin-a, Lee, Joo-yong, Lee, Jun Hee, Lee, Michael, Lee, Min Goo, Lee, Min Jae, Lee, Myung-shik, Lee, Sang Yoon, Lee, Seung-jae, Lee, Stella Y., Lee, Sung Bae, Lee, Won Hee, Lee, Ying-ray, Lee, Yong-ho, Lee, Youngil, Lefebvre, Christophe, Legouis, Renaud, Lei, Yu L., Lei, Yuchen, Leikin, Sergey, Leitinger, Gerd, Lemus, Leticia, Leng, Shuilong, Lenoir, Olivia, Lenz, Guido, Lenz, Heinz Josef, Lenzi, Paola, León, Yolanda, Leopoldino, Andréia M., Leschczyk, Christoph, Leskelä, Stina, Letellier, Elisabeth, Leung, Chi-ting, Leung, Po Sing, Leventhal, Jeremy S., Levine, Beth, Lewis, Patrick A., Ley, Klaus, Li, Bin, Li, Da-qiang, Li, Jianming, Li, Jing, Li, Jiong, Li, Ke, Li, Liwu, Li, Mei, Li, Min, Li, Ming, Li, Mingchuan, Li, Pin-lan, Li, Ming-qing, Li, Qing, Li, Sheng, Li, Tiangang, Li, Wei, Li, Wenming, Li, Xue, Li, Yi-ping, Li, Yuan, Li, Zhiqiang, Li, Zhiyong, Li, Zhiyuan, Lian, Jiqin, Liang, Chengyu, Liang, Qiangrong, Liang, Weicheng, Liang, Yongheng, Liang, Yongtian, Liao, Guanghong, Liao, Lujian, Liao, Mingzhi, Liao, Yung-feng, Librizzi, Mariangela, Lie, Pearl P. Y., Lilly, Mary A., Lim, Hyunjung J., Lima, Thania R.r., Limana, Federica, Lin, Chao, Lin, Chih-wen, Lin, Dar-shong, Lin, Fu-cheng, Lin, Jiandie D., Lin, Kurt M., Lin, Kwang-huei, Lin, Liang-tzung, Lin, Pei-hui, Lin, Qiong, Lin, Shaofeng, Lin, Su-ju, Lin, Wenyu, Lin, Xueying, Lin, Yao-xin, Lin, Yee-shin, Linden, Rafael, Lindner, Paula, Ling, Shuo-chien, Lingor, Paul, Linnemann, Amelia K., Liou, Yih-cherng, Lipinski, Marta M., Lipovšek, Saška, Lira, Vitor A., Lisiak, Natalia, Liton, Paloma B., Liu, Chao, Liu, Ching-hsuan, Liu, Chun-feng, Liu, Cui Hua, Liu, Fang, Liu, Hao, Liu, Hsiao-sheng, Liu, Hua-feng, Liu, Huifang, Liu, Jia, Liu, Jing, Liu, Julia, Liu, Leyuan, Liu, Longhua, Liu, Meilian, Liu, Qin, Liu, Wei, Liu, Wende, Liu, Xiao-hong, Liu, Xiaodong, Liu, Xingguo, Liu, Xu, Liu, Xuedong, Liu, Yanfen, Liu, Yang, Liu, Yueyang, Liu, Yule, Livingston, J. Andrew, Lizard, Gerard, Lizcano, Jose M., Ljubojevic-holzer, Senka, Lleonart, Matilde E., Llobet-navàs, David, Llorente, Alicia, Lo, Chih Hung, Lobato-márquez, Damián, Long, Qi, Long, Yun Chau, Loos, Ben, Loos, Julia A., López, Manuela G., López-doménech, Guillermo, López-guerrero, José Antonio, López-jiménez, Ana T., López-pérez, Óscar, López-valero, Israel, Lorenowicz, Magdalena J., Lorente, Mar, Lorincz, Peter, Lossi, Laura, Lotersztajn, Sophie, Lovat, Penny E., Lovell, Jonathan F., Lovy, Alenka, Lőw, Péter, Lu, Guang, Lu, Haocheng, Lu, Jia-hong, Lu, Jin-jian, Lu, Mengji, Lu, Shuyan, Luciani, Alessandro, Lucocq, John M., Ludovico, Paula, Luftig, Micah A., Luhr, Morten, Luis-ravelo, Diego, Lum, Julian J., Luna-dulcey, Liany, Lund, Anders H., Lund, Viktor K., Lünemann, Jan D., Lüningschrör, Patrick, Luo, Honglin, Luo, Rongcan, Luo, Shouqing, Luo, Zhi, Luparello, Claudio, Lüscher, Bernhard, Luu, Luan, Lyakhovich, Alex, Lyamzaev, Konstantin G., Lystad, Alf Håkon, Lytvynchuk, Lyubomyr, Ma, Alvin C., Ma, Changle, Ma, Mengxiao, Ma, Ning-fang, Ma, Quan-hong, Ma, Xinliang, Ma, Yueyun, Ma, Zhenyi, Macdougald, Ormond A., Macian, Fernando, Macintosh, Gustavo C., Mackeigan, Jeffrey P., Macleod, Kay F., Maday, Sandra, Madeo, Frank, Madesh, Muniswamy, Madl, Tobias, Madrigal-matute, Julio, Maeda, Akiko, Maejima, Yasuhiro, Magarinos, Marta, Mahavadi, Poornima, Maiani, Emiliano, Maiese, Kenneth, Maiti, Panchanan, Maiuri, Maria Chiara, Majello, Barbara, Major, Michael B., Makareeva, Elena, Malik, Fayaz, Mallilankaraman, Karthik, Malorni, Walter, Maloyan, Alina, Mammadova, Najiba, Man, Gene Chi Wai, Manai, Federico, Mancias, Joseph D., Mandelkow, Eva-maria, Mandell, Michael A., Manfredi, Angelo A., Manjili, Masoud H., Manjithaya, Ravi, Manque, Patricio, Manshian, Bella B., Manzano, Raquel, Manzoni, Claudia, Mao, Kai, Marchese, Cinzia, Marchetti, Sandrine, Marconi, Anna Maria, Marcucci, Fabrizio, Mardente, Stefania, Mareninova, Olga A., Margeta, Marta, Mari, Muriel, Marinelli, Sara, Marinelli, Oliviero, Mariño, Guillermo, Mariotto, Sofia, Marshall, Richard S., Marten, Mark R., Martens, Sascha, Martin, Alexandre P.j., Martin, Katie R., Martin, Sara, Martin, Shaun, Martín-segura, Adrián, Martín-acebes, Miguel A., Martin-burriel, Inmaculada, Martin-rincon, Marcos, Martin-sanz, Paloma, Martina, José A., Martinet, Wim, Martinez, Aitor, Martinez, Ana, Martinez, Jennifer, Martinez Velazquez, Moises, Martinez-lopez, Nuria, Martinez-vicente, Marta, Martins, Daniel O., Martins, Joilson O., Martins, Waleska K., Martins-marques, Tania, Marzetti, Emanuele, Masaldan, Shashank, Masclaux-daubresse, Celine, Mashek, Douglas G., Massa, Valentina, Massieu, Lourdes, Masson, Glenn R., Masuelli, Laura, Masyuk, Anatoliy I., Masyuk, Tetyana V., Matarrese, Paola, Matheu, Ander, Matoba, Satoaki, Matsuzaki, Sachiko, Mattar, Pamela, Matte, Alessandro, Mattoscio, Domenico, Mauriz, José L., Mauthe, Mario, Mauvezin, Caroline, Maverakis, Emanual, Maycotte, Paola, Mayer, Johanna, Mazzoccoli, Gianluigi, Mazzoni, Cristina, Mazzulli, Joseph R., Mccarty, Nami, Mcdonald, Christine, Mcgill, Mitchell R., Mckenna, Sharon L., Mclaughlin, Bethann, Mcloughlin, Fionn, Mcniven, Mark A., Mcwilliams, Thomas G., Mechta-grigoriou, Fatima, Medeiros, Tania Catarina, Medina, Diego L., Megeney, Lynn A., Megyeri, Klara, Mehrpour, Maryam, Mehta, Jawahar L., Meijer, Alfred J., Meijer, Annemarie H., Mejlvang, Jakob, Meléndez, Alicia, Melk, Annette, Memisoglu, Gonen, Mendes, Alexandrina F., Meng, Delong, Meng, Fei, Meng, Tian, Menna-barreto, Rubem, Menon, Manoj B., Mercer, Carol, Mercier, Anne E., Mergny, Jean-louis, Merighi, Adalberto, Merkley, Seth D., Merla, Giuseppe, Meske, Volker, Mestre, Ana Cecilia, Metur, Shree Padma, Meyer, Christian, Meyer, Hemmo, Mi, Wenyi, Mialet-perez, Jeanne, Miao, Junying, Micale, Lucia, Miki, Yasuo, Milan, Enrico, Milczarek, Małgorzata, Miller, Dana L., Miller, Samuel I., Miller, Silke, Millward, Steven W., Milosevic, Ira, Minina, Elena A., Mirzaei, Hamed, Mirzaei, Hamid Reza, Mirzaei, Mehdi, Mishra, Amit, Mishra, Nandita, Mishra, Paras Kumar, Misirkic Marjanovic, Maja, Misasi, Roberta, Misra, Amit, Misso, Gabriella, Mitchell, Claire, Mitou, Geraldine, Miura, Tetsuji, Miyamoto, Shigeki, Miyazaki, Makoto, Miyazaki, Mitsunori, Miyazaki, Taiga, Miyazawa, Keisuke, Mizushima, Noboru, Mogensen, Trine H., Mograbi, Baharia, Mohammadinejad, Reza, Mohamud, Yasir, Mohanty, Abhishek, Mohapatra, Sipra, Möhlmann, Torsten, Mohmmed, Asif, Moles, Anna, Moley, Kelle H., Molinari, Maurizio, Mollace, Vincenzo, Møller, Andreas Buch, Mollereau, Bertrand, Mollinedo, Faustino, Montagna, Costanza, Monteiro, Mervyn J., Montella, Andrea, Montes, L. 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Patrick, Murthy, Aditya, Myöhänen, Timo T., Mysorekar, Indira U., Mytych, Jennifer, Nabavi, Seyed Mohammad, Nabissi, Massimo, Nagy, Péter, Nah, Jihoon, Nahimana, Aimable, Nakagawa, Ichiro, Nakamura, Ken, Nakatogawa, Hitoshi, Nandi, Shyam S., Nanjundan, Meera, Nanni, Monica, Napolitano, Gennaro, Nardacci, Roberta, Narita, Masashi, Nassif, Melissa, Nathan, Ilana, Natsumeda, Manabu, Naude, Ryno J., Naumann, Christin, Naveiras, Olaia, Navid, Fatemeh, Nawrocki, Steffan T., Nazarko, Taras Y., Nazio, Francesca, Negoita, Florentina, Neill, Thomas, Neisch, Amanda L., Neri, Luca M., Netea, Mihai G., Neubert, Patrick, Neufeld, Thomas P., Neumann, Dietbert, Neutzner, Albert, Newton, Phillip T., Ney, Paul A., Nezis, Ioannis P., Ng, Charlene C.w., Ng, Tzi Bun, Nguyen, Hang T. T., Nguyen, Long T., Ni, Hong-min, Ní Cheallaigh, Clíona, Ni, Zhenhong, Nicolao, M. 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Bishr, Önal, Gizem, Ondrej, Martin, Ong, Sang-bing, Ong, Sang-ging, Onnis, Anna, Orellana, Juan A., Orellana-muñoz, Sara, Ortega-villaizan, Maria Del Mar, Ortiz-gonzalez, Xilma R., Ortona, Elena, Osiewacz, Heinz D., Osman, Abdel-hamid K., Osta, Rosario, Otegui, Marisa S., Otsu, Kinya, Ott, Christiane, Ottobrini, Luisa, Ou, Jing-hsiung James, Outeiro, Tiago F., Oynebraten, Inger, Ozturk, Melek, Pagès, Gilles, Pahari, Susanta, Pajares, Marta, Pajvani, Utpal B., Pal, Rituraj, Paladino, Simona, Pallet, Nicolas, Palmieri, Michela, Palmisano, Giuseppe, Palumbo, Camilla, Pampaloni, Francesco, Pan, Lifeng, Pan, Qingjun, Pan, Wenliang, Pan, Xin, Panasyuk, Ganna, Pandey, Rahul, Pandey, Udai B., Pandya, Vrajesh, Paneni, Francesco, Pang, Shirley Y., Panzarini, Elisa, Papademetrio, Daniela L., Papaleo, Elena, Papinski, Daniel, Papp, Diana, Park, Eun Chan, Park, Hwan Tae, Park, Ji-man, Park, Jong-in, Park, Joon Tae, Park, Junsoo, Park, Sang Chul, Park, Sang-youel, Parola, Abraham H., Parys, Jan B., Pasquier, Adrien, Pasquier, Benoit, Passos, João F., Pastore, Nunzia, Patel, Hemal H., Patschan, Daniel, Pattingre, Sophie, Pedraza-alva, Gustavo, Pedraza-chaverri, Jose, Pedrozo, Zully, Pei, Gang, Pei, Jianming, Peled-zehavi, Hadas, Pellegrini, Joaquín M., Pelletier, Joffrey, Peñalva, Miguel A., Peng, Di, Peng, Ying, Penna, Fabio, Pennuto, Maria, Pentimalli, Francesca, Pereira, Cláudia Mf, Pereira, Gustavo J.s., Pereira, Lilian C., Pereira De Almeida, Luis, Perera, Nirma D., Pérez-lara, Ángel, Perez-oliva, Ana B., Pérez-pérez, María Esther, Periyasamy, Palsamy, Perl, Andras, Perrotta, Cristiana, Perrotta, Ida, Pestell, Richard G., Petersen, Morten, Petrache, Irina, Petrovski, Goran, Pfirrmann, Thorsten, Pfister, Astrid S., Philips, Jennifer A., Pi, Huifeng, Picca, Anna, Pickrell, Alicia M., Picot, Sandy, Pierantoni, Giovanna M., Pierdominici, Marina, Pierre, Philippe, Pierrefite-carle, Valérie, Pierzynowska, Karolina, Pietrocola, Federico, Pietruczuk, Miroslawa, Pignata, Claudio, Pimentel-muiños, Felipe X., Pinar, Mario, Pinheiro, Roberta O., Pinkas-kramarski, Ronit, Pinton, Paolo, Pircs, Karolina, Piya, Sujan, Pizzo, Paola, Plantinga, Theo S., Platta, Harald W., Plaza-zabala, Ainhoa, Plomann, Markus, Plotnikov, Egor Y., Plun-favreau, Helene, Pluta, Ryszard, Pocock, Roger, Pöggeler, Stefanie, Pohl, Christian, Poirot, Marc, Poletti, Angelo, Ponpuak, Marisa, Popelka, Hana, Popova, Blagovesta, Porta, Helena, Porte Alcon, Soledad, Portilla-fernandez, Eliana, Post, Martin, Potts, Malia B., Poulton, Joanna, Powers, Ted, Prahlad, Veena, Prajsnar, Tomasz K., Praticò, Domenico, Prencipe, Rosaria, Priault, Muriel, Proikas-cezanne, Tassula, Promponas, Vasilis J., Proud, Christopher G., Puertollano, Rosa, Puglielli, Luigi, Pulinilkunnil, Thomas, Puri, Deepika, Puri, Rajat, Puyal, Julien, Qi, Xiaopeng, Qi, Yongmei, Qian, Wenbin, Qiang, Lei, Qiu, Yu, Quadrilatero, Joe, Quarleri, Jorge, Raben, Nina, Rabinowich, Hannah, Ragona, Debora, Ragusa, Michael J., Rahimi, Nader, Rahmati, Marveh, Raia, Valeria, Raimundo, Nuno, Rajasekaran, Namakkal-soorappan, Ramachandra Rao, Sriganesh, Rami, Abdelhaq, Ramírez-pardo, Ignacio, Ramsden, David B., Randow, Felix, Rangarajan, Pundi N., Ranieri, Danilo, Rao, Hai, Rao, Lang, Rao, Rekha, Rathore, Sumit, Ratnayaka, J. Arjuna, Ratovitski, Edward A., Ravanan, Palaniyandi, Ravegnini, Gloria, Ray, Swapan K., Razani, Babak, Rebecca, Vito, Reggiori, Fulvio, Régnier-vigouroux, Anne, Reichert, Andreas S., Reigada, David, Reiling, Jan H., Rein, Theo, Reipert, Siegfried, Rekha, Rokeya Sultana, Ren, Hongmei, Ren, Jun, Ren, Weichao, Renault, Tristan, Renga, Giorgia, Reue, Karen, Rewitz, Kim, Ribeiro De Andrade Ramos, Bruna, Riazuddin, S. Amer, Ribeiro-rodrigues, Teresa M., Ricci, Jean-ehrland, Ricci, Romeo, Riccio, Victoria, Richardson, Des R., Rikihisa, Yasuko, Risbud, Makarand V., Risueño, Ruth M., Ritis, Konstantinos, Rizza, Salvatore, Rizzuto, Rosario, Roberts, Helen C., Roberts, Luke D., Robinson, Katherine J., Roccheri, Maria Carmela, Rocchi, Stephane, Rodney, George G., Rodrigues, Tiago, Rodrigues Silva, Vagner Ramon, Rodriguez, Amaia, Rodriguez-barrueco, Ruth, Rodriguez-henche, Nieves, Rodriguez-rocha, Humberto, Roelofs, Jeroen, Rogers, Robert S., Rogov, Vladimir V., Rojo, Ana I., Rolka, Krzysztof, Romanello, Vanina, Romani, Luigina, Romano, Alessandra, Romano, Patricia S., Romeo-guitart, David, Romero, Luis C., Romero, Montserrat, Roney, Joseph C., Rongo, Christopher, Roperto, Sante, Rosenfeldt, Mathias T., Rosenstiel, Philip, Rosenwald, Anne G., Roth, Kevin A., Roth, Lynn, Roth, Steven, Rouschop, Kasper M.a., Roussel, Benoit D., Roux, Sophie, Rovere-querini, Patrizia, Roy, Ajit, Rozieres, Aurore, Ruano, Diego, Rubinsztein, David C., Rubtsova, Maria P., Ruckdeschel, Klaus, Ruckenstuhl, Christoph, Rudolf, Emil, Rudolf, Rüdiger, Ruggieri, Alessandra, Ruparelia, Avnika Ashok, Rusmini, Paola, Russell, Ryan R., Russo, Gian Luigi, Russo, Maria, Russo, Rossella, Ryabaya, Oxana O., Ryan, Kevin M., Ryu, Kwon-yul, Sabater-arcis, Maria, Sachdev, Ulka, Sacher, Michael, Sachse, Carsten, Sadhu, Abhishek, Sadoshima, Junichi, Safren, Nathaniel, Saftig, Paul, Sagona, Antonia P., Sahay, Gaurav, Sahebkar, Amirhossein, Sahin, Mustafa, Sahin, Ozgur, Sahni, Sumit, Saito, Nayuta, Saito, Shigeru, Saito, Tsunenori, Sakai, Ryohei, Sakai, Yasuyoshi, Sakamaki, Jun-ichi, Saksela, Kalle, Salazar, Gloria, Salazar-degracia, Anna, Salekdeh, Ghasem H., Saluja, Ashok K., Sampaio-marques, Belém, Sanchez, Maria Cecilia, Sanchez-alcazar, Jose A., Sanchez-vera, Victoria, Sancho-shimizu, Vanessa, Sanderson, J. Thomas, Sandri, Marco, Santaguida, Stefano, Santambrogio, Laura, Santana, Magda M., Santoni, Giorgio, Sanz, Alberto, Sanz, Pascual, Saran, Shweta, Sardiello, Marco, Sargeant, Timothy J., Sarin, Apurva, Sarkar, Chinmoy, Sarkar, Sovan, Sarrias, Maria-rosa, Sarkar, Surajit, Sarmah, Dipanka Tanu, Sarparanta, Jaakko, Sathyanarayan, Aishwarya, Sathyanarayanan, Ranganayaki, Scaglione, K. Matthew, Scatozza, Francesca, Schaefer, Liliana, Schafer, Zachary T., Schaible, Ulrich E., Schapira, Anthony H.v., Scharl, Michael, Schatzl, Hermann M., Schein, Catherine H., Scheper, Wiep, Scheuring, David, Schiaffino, Maria Vittoria, Schiappacassi, Monica, Schindl, Rainer, Schlattner, Uwe, Schmidt, Oliver, Schmitt, Roland, Schmidt, Stephen D., Schmitz, Ingo, Schmukler, Eran, Schneider, Anja, Schneider, Bianca E., Schober, Romana, Schoijet, Alejandra C., Schott, Micah B., Schramm, Michael, Schröder, Bernd, Schuh, Kai, Schüller, Christoph, Schulze, Ryan J., Schürmanns, Lea, Schwamborn, Jens C., Schwarten, Melanie, Scialo, Filippo, Sciarretta, Sebastiano, Scott, Melanie J., Scotto, Kathleen W., Scovassi, A. 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M., St. Clair, Daret, Stagni, Venturina, Staiano, Leopoldo, Stalnecker, Clint A., Stankov, Metodi V., Stathopulos, Peter B., Stefan, Katja, Stefan, Sven Marcel, Stefanis, Leonidas, Steffan, Joan S., Steinkasserer, Alexander, Stenmark, Harald, Sterneckert, Jared, Stevens, Craig, Stoka, Veronika, Storch, Stephan, Stork, Björn, Strappazzon, Flavie, Strohecker, Anne Marie, Stupack, Dwayne G., Su, Huanxing, Su, Ling-yan, Su, Longxiang, Suarez-fontes, Ana M., Subauste, Carlos S., Subbian, Selvakumar, Subirada, Paula V., Sudhandiran, Ganapasam, Sue, Carolyn M., Sui, Xinbing, Summers, Corey, Sun, Guangchao, Sun, Jun, Sun, Kang, Sun, Meng-xiang, Sun, Qiming, Sun, Yi, Sun, Zhongjie, Sunahara, Karen K.s., Sundberg, Eva, Susztak, Katalin, Sutovsky, Peter, Suzuki, Hidekazu, Sweeney, Gary, Symons, J. David, Sze, Stephen Cho Wing, Szewczyk, Nathaniel J., Tabęcka-łonczynska, Anna, Tabolacci, Claudio, Tacke, Frank, Taegtmeyer, Heinrich, Tafani, Marco, Tagaya, Mitsuo, Tai, Haoran, Tait, Stephen W. G., Takahashi, Yoshinori, Takats, Szabolcs, Talwar, Priti, Tam, Chit, Tam, Shing Yau, Tampellini, Davide, Tamura, Atsushi, Tan, Chong Teik, Tan, Eng-king, Tan, Ya-qin, Tanaka, Masaki, Tanaka, Motomasa, Tang, Daolin, Tang, Jingfeng, Tang, Tie-shan, Tanida, Isei, Tao, Zhipeng, Taouis, Mohammed, Tatenhorst, Lars, Tavernarakis, Nektarios, Taylor, Allen, Taylor, Gregory A., Taylor, Joan M., Tchetina, Elena, Tee, Andrew R., Tegeder, Irmgard, Teis, David, Teixeira, Natercia, Teixeira-clerc, Fatima, Tekirdag, Kumsal A., Tencomnao, Tewin, Tenreiro, Sandra, Tepikin, Alexei V., Testillano, Pilar S., Tettamanti, Gianluca, Tharaux, Pierre-louis, Thedieck, Kathrin, Thekkinghat, Arvind A., Thellung, Stefano, Thinwa, Josephine W., Thirumalaikumar, V.p., Thomas, Sufi Mary, Thomes, Paul G., Thorburn, Andrew, Thukral, Lipi, Thum, Thomas, Thumm, Michael, Tian, Ling, Tichy, Ales, Till, Andreas, Timmerman, Vincent, Titorenko, Vladimir I., Todi, Sokol V., Todorova, Krassimira, Toivonen, Janne M., Tomaipitinca, Luana, Tomar, Dhanendra, Tomas-zapico, Cristina, Tomić, Sergej, Tong, Benjamin Chun-kit, Tong, Chao, Tong, Xin, Tooze, Sharon A., Torgersen, Maria L., Torii, Satoru, Torres-lópez, Liliana, Torriglia, Alicia, Towers, Christina G., Towns, Roberto, Toyokuni, Shinya, Trajkovic, Vladimir, Tramontano, Donatella, Tran, Quynh-giao, Travassos, Leonardo H., Trelford, Charles B., Tremel, Shirley, Trougakos, Ioannis P., Tsao, Betty P., Tschan, Mario P., Tse, Hung-fat, Tse, Tak Fu, Tsugawa, Hitoshi, Tsvetkov, Andrey S., Tumbarello, David A., Tumtas, Yasin, Tuñón, María J., Turcotte, Sandra, Turk, Boris, Turk, Vito, Turner, Bradley J., Tuxworth, Richard I., Tyler, Jessica K., Tyutereva, Elena V., Uchiyama, Yasuo, Ugun-klusek, Aslihan, Uhlig, Holm H., Ułamek-kozioł, Marzena, Ulasov, Ilya V., Umekawa, Midori, Ungermann, Christian, Unno, Rei, Urbe, Sylvie, Uribe-carretero, Elisabet, Üstün, Suayib, Uversky, Vladimir N, Vaccari, Thomas, Vaccaro, Maria I., Vahsen, Björn F., Vakifahmetoglu-norberg, Helin, Valdor, Rut, Valente, Maria J., Valko, Ayelén, Vallee, Richard B., Valverde, Angela M., Van Den Berghe, Greet, Van Der Veen, Stijn, Van Kaer, Luc, Van Loosdregt, Jorg, Van Wijk, Sjoerd J.l., Vandenberghe, Wim, Vanhorebeek, Ilse, Vannier-santos, Marcos A., Vannini, Nicola, Vanrell, M. Cristina, Vantaggiato, Chiara, Varano, Gabriele, Varela-nieto, Isabel, Varga, Máté, Vasconcelos, M. Helena, Vats, Somya, Vavvas, Demetrios G., Vega-naredo, Ignacio, Vega-rubin-de-celis, Silvia, Velasco, Guillermo, Velázquez, Ariadna P., Vellai, Tibor, Vellenga, Edo, Velotti, Francesca, Verdier, Mireille, Verginis, Panayotis, Vergne, Isabelle, Verkade, Paul, Verma, Manish, Verstreken, Patrik, Vervliet, Tim, Vervoorts, Jörg, Vessoni, Alexandre T., Victor, Victor M., Vidal, Michel, Vidoni, Chiara, Vieira, Otilia V., Vierstra, Richard D., Viganó, Sonia, Vihinen, Helena, Vijayan, Vinoy, Vila, Miquel, Vilar, Marçal, Villalba, José M., Villalobo, Antonio, Villarejo-zori, Beatriz, Villarroya, Francesc, Villarroya, Joan, Vincent, Olivier, Vindis, Cecile, Viret, Christophe, Viscomi, Maria Teresa, Visnjic, Dora, Vitale, Ilio, Vocadlo, David J., Voitsekhovskaja, Olga V., Volonté, Cinzia, Volta, Mattia, Vomero, Marta, Von Haefen, Clarissa, Vooijs, Marc A., Voos, Wolfgang, Vucicevic, Ljubica, Wade-martins, Richard, Waguri, Satoshi, Waite, Kenrick A., Wakatsuki, Shuji, Walker, David W., Walker, Mark J., Walker, Simon A., Walter, Jochen, Wandosell, Francisco G., Wang, Bo, Wang, Chao-yung, Wang, Chen, Wang, Chenran, Wang, Chenwei, Wang, Cun-yu, Wang, Dong, Wang, Fangyang, Wang, Feng, Wang, Fengming, Wang, Guansong, Wang, Han, Wang, Hao, Wang, Hexiang, Wang, Hong-gang, Wang, Jianrong, Wang, Jigang, Wang, Jiou, Wang, Jundong, Wang, Kui, Wang, Lianrong, Wang, Liming, Wang, Maggie Haitian, Wang, Meiqing, Wang, Nanbu, Wang, Pengwei, Wang, Peipei, Wang, Ping, Wang, Qing Jun, Wang, Qing, Wang, Qing Kenneth, Wang, Qiong A., Wang, Wen-tao, Wang, Wuyang, Wang, Xinnan, Wang, Xuejun, Wang, Yan, Wang, Yanchang, Wang, Yanzhuang, Wang, Yen-yun, Wang, Yihua, Wang, Yipeng, Wang, Yu, Wang, Yuqi, Wang, Zhe, Wang, Zhenyu, Wang, Zhouguang, Warnes, Gary, Warnsmann, Verena, Watada, Hirotaka, Watanabe, Eizo, Watchon, Maxinne, Wawrzyńska, Anna, Weaver, Timothy E., Wegrzyn, Grzegorz, Wehman, Ann M., Wei, Huafeng, Wei, Lei, Wei, Taotao, Wei, Yongjie, Weiergräber, Oliver H., Weihl, Conrad C., Weindl, Günther, Weiskirchen, Ralf, Wells, Alan, Wen, Runxia H., Wen, Xin, Werner, Antonia, Weykopf, Beatrice, Wheatley, Sally P., Whitton, J. Lindsay, Whitworth, Alexander J., Wiktorska, Katarzyna, Wildenberg, Manon E., Wileman, Tom, Wilkinson, Simon, Willbold, Dieter, Williams, Brett, Williams, Robin S.b., Williams, Roger L., Williamson, Peter R., Wilson, Richard A., Winner, Beate, Winsor, Nathaniel J., Witkin, Steven S., Wodrich, Harald, Woehlbier, Ute, Wollert, Thomas, Wong, Esther, Wong, Jack Ho, Wong, Richard W., Wong, Vincent Kam Wai, Wong, W. Wei-lynn, Wu, An-guo, Wu, Chengbiao, Wu, Jian, Wu, Junfang, Wu, Kenneth K., Wu, Min, Wu, Shan-ying, Wu, Shengzhou, Wu, Shu-yan, Wu, Shufang, Wu, William K.k., Wu, Xiaohong, Wu, Xiaoqing, Wu, Yao-wen, Wu, Yihua, Xavier, Ramnik J., Xia, Hongguang, Xia, Lixin, Xia, Zhengyuan, Xiang, Ge, Xiang, Jin, Xiang, Mingliang, Xiang, Wei, Xiao, Bin, Xiao, Guozhi, Xiao, Hengyi, Xiao, Hong-tao, Xiao, Jian, Xiao, Lan, Xiao, Shi, Xiao, Yin, Xie, Baoming, Xie, Chuan-ming, Xie, Min, Xie, Yuxiang, Xie, Zhiping, Xie, Zhonglin, Xilouri, Maria, Xu, Congfeng, Xu, En, Xu, Haoxing, Xu, Jing, Xu, Jinrong, Xu, Liang, Xu, Wen Wen, Xu, Xiulong, Xue, Yu, Yakhine-diop, Sokhna M.s., Yamaguchi, Masamitsu, Yamaguchi, Osamu, Yamamoto, Ai, Yamashina, Shunhei, Yan, Shengmin, Yan, Shian-jang, Yan, Zhen, Yanagi, Yasuo, Yang, Chuanbin, Yang, Dun-sheng, Yang, Huan, Yang, Huang-tian, Yang, Hui, Yang, Jin-ming, Yang, Jing, Yang, Jingyu, Yang, Ling, Yang, Liu, Yang, Ming, Yang, Pei-ming, Yang, Qian, Yang, Seungwon, Yang, Shu, Yang, Shun-fa, Yang, Wannian, Yang, Wei Yuan, Yang, Xiaoyong, Yang, Xuesong, Yang, Yi, Yang, Ying, Yao, Honghong, Yao, Shenggen, Yao, Xiaoqiang, Yao, Yong-gang, Yao, Yong-ming, Yasui, Takahiro, Yazdankhah, Meysam, Yen, Paul M., Yi, Cong, Yin, Xiao-ming, Yin, Yanhai, Yin, Zhangyuan, Yin, Ziyi, Ying, Meidan, Ying, Zheng, Yip, Calvin K., Yiu, Stephanie Pei Tung, Yoo, Young H., Yoshida, Kiyotsugu, Yoshii, Saori R., Yoshimori, Tamotsu, Yousefi, Bahman, Yu, Boxuan, Yu, Haiyang, Yu, Jun, Yu, Li, Yu, Ming-lung, Yu, Seong-woon, Yu, Victor C., Yu, W. Haung, Yu, Zhengping, Yu, Zhou, Yuan, Junying, Yuan, Ling-qing, Yuan, Shilin, Yuan, Shyng-shiou F., Yuan, Yanggang, Yuan, Zengqiang, Yue, Jianbo, Yue, Zhenyu, Yun, Jeanho, Yung, Raymond L., Zacks, David N., Zaffagnini, Gabriele, Zambelli, Vanessa O., Zanella, Isabella, Zang, Qun S., Zanivan, Sara, Zappavigna, Silvia, Zaragoza, Pilar, Zarbalis, Konstantinos S., Zarebkohan, Amir, Zarrouk, Amira, Zeitlin, Scott O., Zeng, Jialiu, Zeng, Ju-deng, Žerovnik, Eva, Zhan, Lixuan, Zhang, Bin, Zhang, Donna D., Zhang, Hanlin, Zhang, Hong, Zhang, Honghe, Zhang, Huafeng, Zhang, Huaye, Zhang, Hui, Zhang, Hui-ling, Zhang, Jianbin, Zhang, Jianhua, Zhang, Jing-pu, Zhang, Kalin Y.b., Zhang, Leshuai W., Zhang, Lin, Zhang, Lisheng, Zhang, Lu, Zhang, Luoying, Zhang, Menghuan, Zhang, Peng, Zhang, Sheng, Zhang, Wei, Zhang, Xiangnan, Zhang, Xiao-wei, Zhang, Xiaolei, Zhang, Xiaoyan, Zhang, Xin, Zhang, Xinxin, Zhang, Xu Dong, Zhang, Yang, Zhang, Yanjin, Zhang, Yi, Zhang, Ying-dong, Zhang, Yingmei, Zhang, Yuan-yuan, Zhang, Yuchen, Zhang, Zhe, Zhang, Zhengguang, Zhang, Zhibing, Zhang, Zhihai, Zhang, Zhiyong, Zhang, Zili, Zhao, Haobin, Zhao, Lei, Zhao, Shuang, Zhao, Tongbiao, Zhao, Xiao-fan, Zhao, Ying, Zhao, Yongchao, Zhao, Yongliang, Zhao, Yuting, Zheng, Guoping, Zheng, Kai, Zheng, Ling, Zheng, Shizhong, Zheng, Xi-long, Zheng, Yi, Zheng, Zu-guo, Zhivotovsky, Boris, Zhong, Qing, Zhou, Ao, Zhou, Ben, Zhou, Cefan, Zhou, Gang, Zhou, Hao, Zhou, Hong, Zhou, Hongbo, Zhou, Jie, Zhou, Jing, Zhou, Jiyong, Zhou, Kailiang, Zhou, Rongjia, Zhou, Xu-jie, Zhou, Yanshuang, Zhou, Yinghong, Zhou, Yubin, Zhou, Zheng-yu, Zhou, Zhou, Zhu, Binglin, Zhu, Changlian, Zhu, Guo-qing, Zhu, Haining, Zhu, Hongxin, Zhu, Hua, Zhu, Wei-guo, Zhu, Yanping, Zhu, Yushan, Zhuang, Haixia, Zhuang, Xiaohong, Zientara-rytter, Katarzyna, Zimmermann, Christine M., Ziviani, Elena, Zoladek, Teresa, Zong, Wei-xing, Zorov, Dmitry B., Zorzano, Antonio, Zou, Weiping, Zou, Zhen, Zou, Zhengzhi, Zuryn, Steven, Zwerschke, Werner, Brand-saberi, Beate, Dong, X. Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith C., Stallings, Christina L., and Tong, Chun-kit
Abstract: In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
Published: 2021
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28. The Early Dark Sector, the Hubble Tension, and the Swampland

Author: McDonough, Evan, Lin, Meng-Xiang, Hill, J. Colin, Hu, Wayne, Zhou, Shengjia, McDonough, Evan, Lin, Meng-Xiang, Hill, J. Colin, Hu, Wayne, and Zhou, Shengjia
Abstract: We consider the interplay of the Early Dark Energy (EDE) model, the Swampland Distance Conjecture (SDC), and cosmological parameter tensions. EDE is a proposed resolution of the Hubble tension relying upon a near-Planckian scalar field excursion, while the SDC predicts an exponential sensitivity of masses of other fields to such an excursion, $m\propto e^{-c|\Delta \phi|/M_{\rm pl}}$ with $c\sim{\cal O}(1)$. Meanwhile, EDE is in tension with large-scale structure (LSS) data, due to shifts in the standard $\Lambda$CDM parameters necessary to fit the cosmic microwave background (CMB). One might hope that a proper treatment of the model, e.g., accounting for the SDC, may ameliorate the tension with LSS. Motivated by these considerations, we introduce the Early Dark Sector (EDS) model, wherein the mass of dark matter is exponentially sensitive to super-Planckian field excursions of the EDE scalar. The EDS model exhibits new phenomenology in both the early and late universe, the latter due to an EDE-mediated dark matter self-interaction. This dark matter-philic "fifth force", while constrained to be small, remains active in the late universe and is not screened in virialized halos. We find that the new interaction with dark matter partially resolves the LSS tension. However, the marginalized posteriors are nonetheless consistent with $f_{\rm EDE}=0$ at 95$\%$ CL once the Dark Energy Survey Year 3 measurement of $S_8$ is included. We study constraints on the model from Atacama Cosmology Telescope data, and find a factor of two improvement on the error bar on the SDC parameter $c$, along with an increased preference for the EDE component. We discuss the implications of these constraints for the SDC, and find the tightest observational constraints to date on a swampland parameter, suggesting that an EDE description of cosmological data is in tension with the SDC.
Published: 2021

29. Gravitational wave propagation beyond general relativity: waveform distortions and echoes

Author: Ezquiaga, Jose Maria, Hu, Wayne, Lagos, Macarena, Lin, Meng-Xiang, Ezquiaga, Jose Maria, Hu, Wayne, Lagos, Macarena, and Lin, Meng-Xiang
Abstract: We study the cosmological propagation of gravitational waves (GWs) beyond general relativity (GR) across homogeneous and isotropic backgrounds. We consider scenarios in which GWs interact with an additional tensor field and use a parametrized phenomenological approach that generically describes their coupled equations of motion. We analyze four distinct classes of derivative and non-derivative interactions: mass, friction, velocity, and chiral. We apply the WKB formalism to account for the cosmological evolution and obtain analytical solutions to these equations. We corroborate these results by analyzing numerically the propagation of a toy GW signal. We then proceed to use the analytical results to study the modified propagation of realistic GWs from merging compact binaries, assuming that the GW signal emitted is the same as in GR. We generically find that tensor interactions lead to copies of the originally emitted GW signal, each one with its own possibly modified dispersion relation. These copies can travel coherently and interfere with each other leading to a scrambled GW signal, or propagate decoherently and lead to echoes arriving at different times at the observer that could be misidentified as independent GW events. Depending on the type of tensor interaction, the detected GW signal may exhibit amplitude and phase distortions with respect to a GW waveform in GR, as well as birefringence effects. We discuss observational probes of these tensor interactions with both individual GW events, as well as population studies for both ground- and space-based detectors., Comment: Updated to journal version
Published: 2021
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30. Structural and molecular biology of hepatitis E virus

Author: Wang, Bo, Meng, Xiang-Jin, Wang, Bo, and Meng, Xiang-Jin
Abstract: Hepatitis E virus (HEV) is one of the most common causes of acute viral hepatitis, mainly transmitted by fecal-oral route but has also been linked to fulminant hepatic failure, chronic hepatitis, and extrahepatic neurological and renal diseases. HEV is an emerging zoonotic pathogen with a broad host range, and strains of HEV from numerous animal species are known to cross species barriers and infect humans. HEV is a single-stranded, positive-sense RNA virus in the family Hepeviridae. The genome typically contains three open reading frames (ORFs): ORF1 encodes a nonstructural polyprotein for virus replication and transcription, ORF2 encodes the capsid protein that elicits neutralizing antibodies, and ORF3, which partially overlaps ORF2, encodes a multifunctional protein involved in virion morphogenesis and pathogenesis. HEV virions are non-enveloped spherical particles in feces but exist as quasi-enveloped particles in circulating blood. Two types of HEV virus-like particles (VLPs), small T = 1 (270 Å) and native virion-sized T = 3 (320–340 Å) have been reported. There exist two distinct forms of capsid protein, the secreted form (ORF2S) inhibits antibody neutralization, whereas the capsid-associated form (ORF2C) self-assembles to VLPs. Four cis-reactive elements (CREs) containing stem-loops from secondary RNA structures have been identified in the non-coding regions and are critical for virus replication. This mini-review discusses the current knowledge and gaps regarding the structural and molecular biology of HEV with emphasis on the virion structure, genomic organization, secondary RNA structures, viral proteins and their functions, and life cycle of HEV.
Published: 2021
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31. Gastric adenocarcinoma of the fundic gland: A review of clinicopathological characteristics, treatment and prognosis

Author: Meng, Xiang-Yu, Yang, Guang, Dong, Cheng-Ji, Zheng, Ru-Yi, Meng, Xiang-Yu, Yang, Guang, Dong, Cheng-Ji, and Zheng, Ru-Yi
Abstract: Gastric adenocarcinoma of the fundic gland is a rare, well-differentiated gastric cancer entity, and very few patients transition to poorly differentiated tubular adenocarcinoma during progression. Gastric adenocarcinoma of the fundic gland originates from the mucosa of the gastric fundic gland, usually without chronic gastritis or intestinal metaplasia. Histologically, the tumor cells are closely arranged to form anastomosing tubular glands, and more than 95% of tumor cells differentiate towards chief cells. Most gastric adenocarcinoma of the fundic gland cases are characterized by submucosal involvement, but the tumor volume is usually small, with lymphatic and vascular invasion rarely observed. Therefore, endoscopic submucosal dissection can be an ideal treatment, leading to a favorable prognosis, and recurrence and metastasis of the disease are uncommon.
Published: 2021

32. Structural and molecular biology of hepatitis E virus

Author: Center for Emerging, Zoonotic, and Arthropod-borne Pathogens, Biomedical Sciences and Pathobiology, Wang, Bo, Meng, Xiang-Jin, Center for Emerging, Zoonotic, and Arthropod-borne Pathogens, Biomedical Sciences and Pathobiology, Wang, Bo, and Meng, Xiang-Jin
Abstract: Hepatitis E virus (HEV) is one of the most common causes of acute viral hepatitis, mainly transmitted by fecal-oral route but has also been linked to fulminant hepatic failure, chronic hepatitis, and extrahepatic neurological and renal diseases. HEV is an emerging zoonotic pathogen with a broad host range, and strains of HEV from numerous animal species are known to cross species barriers and infect humans. HEV is a single-stranded, positive-sense RNA virus in the family Hepeviridae. The genome typically contains three open reading frames (ORFs): ORF1 encodes a nonstructural polyprotein for virus replication and transcription, ORF2 encodes the capsid protein that elicits neutralizing antibodies, and ORF3, which partially overlaps ORF2, encodes a multifunctional protein involved in virion morphogenesis and pathogenesis. HEV virions are non-enveloped spherical particles in feces but exist as quasi-enveloped particles in circulating blood. Two types of HEV virus-like particles (VLPs), small T = 1 (270 Å) and native virion-sized T = 3 (320–340 Å) have been reported. There exist two distinct forms of capsid protein, the secreted form (ORF2S) inhibits antibody neutralization, whereas the capsid-associated form (ORF2C) self-assembles to VLPs. Four cis-reactive elements (CREs) containing stem-loops from secondary RNA structures have been identified in the non-coding regions and are critical for virus replication. This mini-review discusses the current knowledge and gaps regarding the structural and molecular biology of HEV with emphasis on the virion structure, genomic organization, secondary RNA structures, viral proteins and their functions, and life cycle of HEV.
Published: 2021

33. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Author: Klionsky, D, Abdel-Aziz, A, Abdelfatah, S, Abdellatif, M, Abdoli, A, Abel, S, Abeliovich, H, Abildgaard, M, Abudu, Y, Acevedo-Arozena, A, Adamopoulos, I, Adeli, K, Adolph, T, Adornetto, A, Aflaki, E, Agam, G, Agarwal, A, Aggarwal, B, Agnello, M, Agostinis, P, Agrewala, J, Agrotis, A, Aguilar, P, Ahmad, S, Ahmed, Z, Ahumada-Castro, U, Aits, S, Aizawa, S, Akkoc, Y, Akoumianaki, T, Akpinar, H, Al-Abd, A, Al-Akra, L, Al-Gharaibeh, A, Alaoui-Jamali, M, Alberti, S, Alcocer-Gómez, E, Alessandri, C, Ali, M, Alim Al-Bari, M, Aliwaini, S, Alizadeh, J, Almacellas, E, Almasan, A, Alonso, A, Alonso, G, Altan-Bonnet, N, Altieri, D, Álvarez, É, Alves, S, Alves da Costa, C, Alzaharna, M, Amadio, M, Amantini, C, Amaral, C, Ambrosio, S, Amer, A, Ammanathan, V, An, Z, Andersen, S, Andrabi, S, Andrade-Silva, M, Andres, A, Angelini, S, Ann, D, Anozie, U, Ansari, M, Antas, P, Antebi, A, Antón, Z, Anwar, T, Apetoh, L, Apostolova, N, Araki, T, Araki, Y, Arasaki, K, Araújo, W, Araya, J, Arden, C, 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Abstract: In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
Published: 2021

34. ANALYSIS OF THE INFLUENCE OF THE IDEOLOGICAL AND POLITICAL EDUCATION DISCOURSE POWER ON STUDENTS’ PSYCHOLOGICAL EMOTION UNDER THE PERSPECTIVE OF INTERNET PLUS

Author: Zhu, Xunchun, Meng, Xiang, Zhu, Xunchun, and Meng, Xiang
Published: 2021

35. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Author: Klionsky, Daniel J, Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie H, Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis E, Adeli, Khosrow, Adolph, Timon E, Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat B, Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed N, Agrotis, Alexander, Aguilar, Patricia V, Ahmad, S Tariq, Ahmed, Zubair M, Ahumada-Castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-Abd, Ahmed M, Al-Akra, Lina, Al-Gharaibeh, Abeer, Alaoui-Jamali, Moulay A, Alberti, Simon, Alcocer-Gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-Bari, M Abdul, Aliwaini, Saeb, Alizadeh, Javad, Almacellas, Eugènia, Almasan, Alexandru, Alonso, Alicia, Alonso, Guillermo D, Altan-Bonnet, Nihal, Altieri, Dario C, Álvarez, Élida M C, Alves, Sara, Alves da Costa, Cristine, Alzaharna, Mazen M, Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal O, Ammanathan, Veena, An, Zhenyi, Andersen, Stig U, Andrabi, Shaida A, Andrade-Silva, Magaiver, Andres, Allen M, Angelini, Sabrina, Ann, David, Anozie, Uche C, Ansari, Mohammad Y, Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner L, Araya, Jun, Arden, Catherine, Arévalo, Maria-Angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen R, Armstrong-James, Darius, Arnauné-Pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela S, Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-Fabian, Osnat, Atanasov, Atanas G, Au, Alicia K, Auberger, Patrick, Auner, Holger W, Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Ávalos, Yenniffer, Aveic, Sanja, Aveleira, Célia Alexandra, Avin-Wittenberg, Tamar, Aydin, Yucel, Ayton, Scott, Ayyadevara, Srinivas, Azzopardi, Maria, Baba, Misuzu, Backer, Jonathan M, Backues, Steven K, Bae, Dong-Hun, Bae, Ok-Nam, Bae, Soo Han, Baehrecke, Eric H, Baek, Ahruem, Baek, Seung-Hoon, Baek, Sung Hee, Bagetta, Giacinto, Bagniewska-Zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xiyuan, Bai, Yidong, Bairagi, Nandadulal, Baksi, Shounak, Balbi, Teresa, Baldari, Cosima T, Balduini, Walter, Ballabio, Andrea, Ballester, Maria, Balazadeh, Salma, Balzan, Rena, Bandopadhyay, Rina, Banerjee, Sreeparna, Banerjee, Sulagna, Bánréti, Ágnes, Bao, Yan, Baptista, Mauricio S, Baracca, Alessandra, Barbati, Cristiana, Bargiela, Ariadna, Barilà, Daniela, Barlow, Peter G, Barmada, Sami J, Barreiro, Esther, Barreto, George E, Bartek, Jiri, Bartel, Bonnie, Bartolome, Alberto, Barve, Gaurav R, Basagoudanavar, Suresh H, Bassham, Diane C, Bast, Robert C, Basu, Alakananda, Batoko, Henri, Batten, Isabella, Baulieu, Etienne E, Baumgarner, Bradley L, Bayry, Jagadeesh, Beale, Rupert, Beau, Isabelle, Beaumatin, Florian, Bechara, Luiz R G, Beck, George R, Beers, Michael F, Begun, Jakob, Behrends, Christian, Behrens, Georg M N, Bei, Roberto, Bejarano, Eloy, Bel, Shai, Behl, Christian, Belaid, Amine, Belgareh-Touzé, Naïma, Bellarosa, Cristina, Belleudi, Francesca, Belló Pérez, Melissa, Bello-Morales, Raquel, Beltran, Jackeline Soares de Oliveira, Beltran, Sebastián, Benbrook, Doris Mangiaracina, Bendorius, Mykolas, Benitez, Bruno A, Benito-Cuesta, Irene, Bensalem, Julien, Berchtold, Martin W, Berezowska, Sabina, Bergamaschi, Daniele, Bergami, Matteo, Bergmann, Andreas, Berliocchi, Laura, Berlioz-Torrent, Clarisse, Bernard, Amélie, Berthoux, Lionel, Besirli, Cagri G, Besteiro, Sebastien, Betin, Virginie M, Beyaert, Rudi, Bezbradica, Jelena S, Bhaskar, Kiran, Bhatia-Kissova, Ingrid, Bhattacharya, Resham, Bhattacharya, Sujoy, Bhattacharyya, Shalmoli, Bhuiyan, Md. Shenuarin, Bhutia, Sujit Kumar, Bi, Lanrong, Bi, Xiaolin, Biden, Trevor J, Bijian, Krikor, Billes, Viktor A, Binart, Nadine, Bincoletto, Claudia, Birgisdottir, Asa B, Bjorkoy, Geir, Blanco, Gonzalo, Blas-Garcia, Ana, Blasiak, Janusz, Blomgran, Robert, Blomgren, Klas, Blum, Janice S, Boada-Romero, Emilio, Boban, Mirta, Boesze-Battaglia, Kathleen, Boeuf, Philippe, Boland, Barry, Bomont, Pascale, Bonaldo, Paolo, Bonam, Srinivasa Reddy, Bonfili, Laura, Bonifacino, Juan S, Boone, Brian A, Bootman, Martin D, Bordi, Matteo, Borner, Christoph, Bornhauser, Beat C, Borthakur, Gautam, Bosch, Jürgen, Bose, Santanu, Botana, Luis M, Botas, Juan, Boulanger, Chantal M, Boulton, Michael E, Bourdenx, Mathieu, Bourgeois, Benjamin, Bourke, Nollaig M, Bousquet, Guilhem, Boya, Patricia, Bozhkov, Peter V, Bozi, Luiz H M, Bozkurt, Tolga O, Brackney, Doug E, Brandts, Christian H, Braun, Ralf J, Braus, Gerhard H, Bravo-Sagua, Roberto, Bravo-San Pedro, José M, Brest, Patrick, Bringer, Marie-Agnès, Briones-Herrera, Alfredo, Broaddus, V Courtney, Brodersen, Peter, Brodsky, Jeffrey L, Brody, Steven L, Bronson, Paola G, Bronstein, Jeff M, Brown, Carolyn N, Brown, Rhoderick E, Brum, Patricia C, Brumell, John H, Brunetti-Pierri, Nicola, Bruno, Daniele, Bryson-Richardson, Robert J, Bucci, Cecilia, Buchrieser, Carmen, Bueno, Marta, Buitrago-Molina, Laura Elisa, Buraschi, Simone, Buch, Shilpa, Buchan, J Ross, Buckingham, Erin M, Budak, Hikmet, Budini, Mauricio, Bultynck, Geert, Burada, Florin, Burgoyne, Joseph R, Burón, M Isabel, Bustos, Victor, Büttner, Sabrina, Butturini, Elena, Byrd, Aaron, Cabas, Isabel, Cabrera-Benitez, Sandra, Cadwell, Ken, Cai, Jingjing, Cai, Lu, Cai, Qian, Cairó, Montserrat, Calbet, Jose A, Caldwell, Guy A, Caldwell, Kim A, Call, Jarrod A, Calvani, Riccardo, Calvo, Ana C, Calvo-Rubio Barrera, Miguel, Camara, Niels O S, Camonis, Jacques H, Camougrand, Nadine, Campanella, Michelangelo, Campbell, Edward M, Campbell-Valois, François-Xavier, Campello, Silvia, Campesi, Ilaria, Campos, Juliane C, Camuzard, Olivier, Cancino, Jorge, Candido de Almeida, Danilo, Canesi, Laura, Caniggia, Isabella, Canonico, Barbara, Cantí, Carles, Cao, Bin, Caraglia, Michele, Caramés, Beatriz, Carchman, Evie H, Cardenal-Muñoz, Elena, Cardenas, Cesar, Cardenas, Luis, Cardoso, Sandra M, Carew, Jennifer S, Carle, Georges F, Carleton, Gillian, Carloni, Silvia, Carmona-Gutierrez, Didac, Carneiro, Leticia A, Carnevali, Oliana, Carosi, Julian M, Carra, Serena, Carrier, Alice, Carrier, Lucie, Carroll, Bernadette, Carter, A Brent, Carvalho, Andreia Neves, Casanova, Magali, Casas, Caty, Casas, Josefina, Cassioli, Chiara, Castillo, Eliseo F, Castillo, Karen, Castillo-Lluva, Sonia, Castoldi, Francesca, Castori, Marco, Castro, Ariel F, Castro-Caldas, Margarida, Castro-Hernandez, Javier, Castro-Obregon, Susana, Catz, Sergio D, Cavadas, Claudia, Cavaliere, Federica, Cavallini, Gabriella, Cavinato, Maria, Cayuela, Maria L, Cebollada Rica, Paula, Cecarini, Valentina, Cecconi, Francesco, Cechowska-Pasko, Marzanna, Cenci, Simone, Ceperuelo-Mallafré, Victòria, Cerqueira, João J, Cerutti, Janete M, Cervia, Davide, Cetintas, Vildan Bozok, Cetrullo, Silvia, Chae, Han-Jung, Chagin, Andrei S, Chai, Chee-Yin, Chakrabarti, Gopal, Chakrabarti, Oishee, Chakraborty, Tapas, Chakraborty, Trinad, Chami, Mounia, Chamilos, Georgios, Chan, David W, Chan, Edmond Y W, Chan, Edward D, Chan, H Y Edwin, Chan, Helen H, Chan, Hung, Chan, Matthew T V, Chan, Yau Sang, Chandra, Partha K, Chang, Chih-Peng, Chang, Chunmei, Chang, Hao-Chun, Chang, Kai, Chao, Jie, Chapman, Tracey, Charlet-Berguerand, Nicolas, Chatterjee, Samrat, Chaube, Shail K, Chaudhary, Anu, Chauhan, Santosh, Chaum, Edward, Checler, Frédéric, Cheetham, Michael E, Chen, Chang-Shi, Chen, Guang-Chao, Chen, Jian-Fu, Chen, Liam L, Chen, Leilei, Chen, Lin, Chen, Mingliang, Chen, Mu-Kuan, Chen, Ning, Chen, Quan, Chen, Ruey-Hwa, Chen, Shi, Chen, Wei, Chen, Weiqiang, Chen, Xin-Ming, Chen, Xiong-Wen, Chen, Xu, Chen, Yan, Chen, Ye-Guang, Chen, Yingyu, Chen, Yongqiang, Chen, Yu-Jen, Chen, Yue-Qin, Chen, Zhefan Stephen, Chen, Zhi, Chen, Zhi-Hua, Chen, Zhijian J, Chen, Zhixiang, Cheng, Hanhua, Cheng, Jun, Cheng, Shi-Yuan, Cheng, Wei, Cheng, Xiaodong, Cheng, Xiu-Tang, Cheng, Yiyun, Cheng, Zhiyong, Chen, Zhong, Cheong, Heesun, Cheong, Jit Kong, Chernyak, Boris V, Cherry, Sara, Cheung, Chi Fai Randy, Cheung, Chun Hei Antonio, Cheung, King-Ho, Chevet, Eric, Chi, Richard J, Chiang, Alan Kwok Shing, Chiaradonna, Ferdinando, Chiarelli, Roberto, Chiariello, Mario, Chica, Nathalia, Chiocca, Susanna, Chiong, Mario, Chiou, Shih-Hwa, Chiramel, Abhilash I, Chiurchiù, Valerio, Cho, Dong-Hyung, Choe, Seong-Kyu, Choi, Augustine M K, Choi, Mary E, Choudhury, Kamalika Roy, Chow, Norman S, Chu, Charleen T, Chua, Jason P, Chua, John Jia En, Chung, Hyewon, Chung, Kin Pan, Chung, Seockhoon, Chung, So-Hyang, Chung, Yuen-Li, Cianfanelli, Valentina, Ciechomska, Iwona A, Cifuentes, Mariana, Cinque, Laura, Cirak, Sebahattin, Cirone, Mara, Clague, Michael J, Clarke, Robert, Clementi, Emilio, Coccia, Eliana M, Codogno, Patrice, Cohen, Ehud, Cohen, Mickael M, Colasanti, Tania, Colasuonno, Fiorella, Colbert, Robert A, Colell, Anna, Čolić, Miodrag, Coll, Nuria S, Collins, Mark O, Colombo, María I, Colón-Ramos, Daniel A, Combaret, Lydie, Comincini, Sergio, Cominetti, Márcia R, Consiglio, Antonella, Conte, Andrea, Conti, Fabrizio, Contu, Viorica Raluca, Cookson, Mark R, Coombs, Kevin M, Coppens, Isabelle, Corasaniti, Maria Tiziana, Corkery, Dale P, Cordes, Nils, Cortese, Katia, Costa, Maria do Carmo, Costantino, Sarah, Costelli, Paola, Coto-Montes, Ana, Crack, Peter J, Crespo, Jose L, Criollo, Alfredo, Crippa, Valeria, Cristofani, Riccardo, Csizmadia, Tamas, Cuadrado, Antonio, Cui, Bing, Cui, Jun, Cui, Yixian, Cui, Yong, Culetto, Emmanuel, Cumino, Andrea C, Cybulsky, Andrey V, Czaja, Mark J, Czuczwar, Stanislaw J, D’Adamo, Stefania, D’Amelio, Marcello, D’Arcangelo, Daniela, D’Lugos, Andrew C, D’Orazi, Gabriella, da Silva, James A, Dafsari, Hormos Salimi, Dagda, Ruben K, Dagdas, Yasin, Daglia, Maria, Dai, Xiaoxia, Dai, Yun, Dai, Yuyuan, Dal Col, Jessica, Dalhaimer, Paul, Dalla Valle, Luisa, Dallenga, Tobias, Dalmasso, Guillaume, Damme, Markus, Dando, Ilaria, Dantuma, Nico P, Darling, April L, Das, Hiranmoy, Dasarathy, Srinivasan, Dasari, Santosh K, Dash, Srikanta, Daumke, Oliver, Dauphinee, Adrian N, Davies, Jeffrey S, Dávila, Valeria A, Davis, Roger J, Davis, Tanja, Dayalan Naidu, Sharadha, De Amicis, Francesca, De Bosscher, Karolien, De Felice, Francesca, De Franceschi, Lucia, De Leonibus, Chiara, de Mattos Barbosa, Mayara G, De Meyer, Guido R Y, De Milito, Angelo, De Nunzio, Cosimo, De Palma, Clara, De Santi, Mauro, De Virgilio, Claudio, De Zio, Daniela, Debnath, Jayanta, DeBosch, Brian J, Decuypere, Jean-Paul, Deehan, Mark A, Deflorian, Gianluca, DeGregori, James, Dehay, Benjamin, Del Rio, Gabriel, Delaney, Joe R, Delbridge, Lea M D, Delorme-Axford, Elizabeth, Delpino, M Victoria, Demarchi, Francesca, Dembitz, Vilma, Demers, Nicholas D, Deng, Hongbin, Deng, Zhiqiang, Dengjel, Joern, Dent, Paul, Denton, Donna, DePamphilis, Melvin L, Der, Channing J, Deretic, Vojo, Descoteaux, Albert, Devis, Laura, Devkota, Sushil, Devuyst, Olivier, Dewson, Grant, Dharmasivam, Mahendiran, Dhiman, Rohan, di Bernardo, Diego, Di Cristina, Manlio, Di Domenico, Fabio, Di Fazio, Pietro, Di Fonzo, Alessio, Di Guardo, Giovanni, Di Guglielmo, Gianni M, Di Leo, Luca, Di Malta, Chiara, Di Nardo, Alessia, Di Rienzo, Martina, Di Sano, Federica, Diallinas, George, Diao, Jiajie, Diaz-Araya, Guillermo, Díaz-Laviada, Inés, Dickinson, Jared M, Diederich, Marc, Dieudé, Mélanie, Dikic, Ivan, Ding, Shiping, Ding, Wen-Xing, Dini, Luciana, Dinić, Jelena, Dinic, Miroslav, Dinkova-Kostova, Albena T, Dionne, Marc S, Distler, Jörg H W, Diwan, Abhinav, Dixon, Ian M C, Djavaheri-Mergny, Mojgan, Dobrinski, Ina, Dobrovinskaya, Oxana, Dobrowolski, Radek, Dobson, Renwick C J, Đokić, Jelena, Dokmeci Emre, Serap, Donadelli, Massimo, Dong, Bo, Dong, Xiaonan, Dong, Zhiwu, Dorn II, Gerald W, Dotsch, Volker, Dou, Huan, Dou, Juan, Dowaidar, Moataz, Dridi, Sami, Drucker, Liat, Du, Ailian, Du, Caigan, Du, Guangwei, Du, Hai-Ning, Du, Li-Lin, du Toit, André, Duan, Shao-Bin, Duan, Xiaoqiong, Duarte, Sónia P, Dubrovska, Anna, Dunlop, Elaine A, Dupont, Nicolas, Durán, Raúl V, Dwarakanath, Bilikere S, Dyshlovoy, Sergey A, Ebrahimi-Fakhari, Darius, Eckhart, Leopold, Edelstein, Charles L, Efferth, Thomas, Eftekharpour, Eftekhar, Eichinger, Ludwig, Eid, Nabil, Eisenberg, Tobias, Eissa, N Tony, Eissa, Sanaa, Ejarque, Miriam, El Andaloussi, Abdeljabar, El-Hage, Nazira, El-Naggar, Shahenda, Eleuteri, Anna Maria, El-Shafey, Eman S, Elgendy, Mohamed, Eliopoulos, Aristides G, Elizalde, María M, Elks, Philip M, Elsasser, Hans-Peter, Elsherbiny, Eslam S, Emerling, Brooke M, Emre, N C Tolga, Eng, Christina H, Engedal, Nikolai, Engelbrecht, Anna-Mart, Engelsen, Agnete S T, Enserink, Jorrit M, Escalante, Ricardo, Esclatine, Audrey, Escobar-Henriques, Mafalda, Eskelinen, Eeva-Liisa, Espert, Lucile, Eusebio, Makandjou-Ola, Fabrias, Gemma, Fabrizi, Cinzia, Facchiano, Antonio, Facchiano, Francesco, Fadeel, Bengt, Fader, Claudio, Faesen, Alex C, Fairlie, W Douglas, Falcó, Alberto, Falkenburger, Bjorn H, Fan, Daping, Fan, Jie, Fan, Yanbo, Fang, Evandro F, Fang, Yanshan, Fang, Yognqi, Fanto, Manolis, Farfel-Becker, Tamar, Faure, Mathias, Fazeli, Gholamreza, Fedele, Anthony O, Feldman, Arthur M, Feng, Du, Feng, Jiachun, Feng, Lifeng, Feng, Yibin, Feng, Yuchen, Feng, Wei, Fenz Araujo, Thais, Ferguson, Thomas A, Fernández, Álvaro F, Fernandez-Checa, Jose C, Fernández-Veledo, Sonia, Fernie, Alisdair R, Ferrante, Anthony W, Ferraresi, Alessandra, Ferrari, Merari F, Ferreira, Julio C B, Ferro-Novick, Susan, Figueras, Antonio, Filadi, Riccardo, Filigheddu, Nicoletta, Filippi-Chiela, Eduardo, Filomeni, Giuseppe, Fimia, Gian Maria, Fineschi, Vittorio, Finetti, Francesca, Finkbeiner, Steven, Fisher, Edward A, Fisher, Paul B, Flamigni, Flavio, Fliesler, Steven J, Flo, Trude H, Florance, Ida, Florey, Oliver, Florio, Tullio, Fodor, Erika, Follo, Carlo, Fon, Edward A, Forlino, Antonella, Fornai, Francesco, Fortini, Paola, Fracassi, Anna, Fraldi, Alessandro, Franco, Brunella, Franco, Rodrigo, Franconi, Flavia, Frankel, Lisa B, Friedman, Scott L, Fröhlich, Leopold F, Frühbeck, Gema, Fuentes, Jose M, Fujiki, Yukio, Fujita, Naonobu, Fujiwara, Yuuki, Fukuda, Mitsunori, Fulda, Simone, Furic, Luc, Furuya, Norihiko, Fusco, Carmela, Gack, Michaela U, Gaffke, Lidia, Galadari, Sehamuddin, Galasso, Alessia, Galindo, Maria F, Gallolu Kankanamalage, Sachith, Galluzzi, Lorenzo, Galy, Vincent, Gammoh, Noor, Gan, Boyi, Ganley, Ian G, Gao, Feng, Gao, Hui, Gao, Minghui, Gao, Ping, Gao, Shou-Jiang, Gao, Wentao, Gao, Xiaobo, Garcera, Ana, Garcia, Maria Noé, Garcia, Verónica E, García-Del Portillo, Francisco, Garcia-Escudero, Vega, Garcia-Garcia, Aracely, Garcia-Macia, Marina, García-Moreno, Diana, Garcia-Ruiz, Carmen, García-Sanz, Patricia, Garg, Abhishek D, Gargini, Ricardo, Garofalo, Tina, Garry, Robert F, Gassen, Nils C, Gatica, Damian, Ge, Liang, Ge, Wanzhong, Geiss-Friedlander, Ruth, Gelfi, Cecilia, Genschik, Pascal, Gentle, Ian E, Gerbino, Valeria, Gerhardt, Christoph, Germain, Kyla, Germain, Marc, Gewirtz, David A, Ghasemipour Afshar, Elham, Ghavami, Saeid, Ghigo, Alessandra, Ghosh, Manosij, Giamas, Georgios, Giampietri, Claudia, Giatromanolaki, Alexandra, Gibson, Gary E, Gibson, Spencer B, Ginet, Vanessa, Giniger, Edward, Giorgi, Carlotta, Girao, Henrique, Girardin, Stephen E, Giridharan, Mridhula, Giuliano, Sandy, Giulivi, Cecilia, Giuriato, Sylvie, Giustiniani, Julien, Gluschko, Alexander, Goder, Veit, Goginashvili, Alexander, Golab, Jakub, Goldstone, David C, Golebiewska, Anna, Gomes, Luciana R, Gomez, Rodrigo, Gómez-Sánchez, Rubén, Gomez-Puerto, Maria Catalina, Gomez-Sintes, Raquel, Gong, Qingqiu, Goni, Felix M, González-Gallego, Javier, Gonzalez-Hernandez, Tomas, Gonzalez-Polo, Rosa A, Gonzalez-Reyes, Jose A, González-Rodríguez, Patricia, Goping, Ing Swie, Gorbatyuk, Marina S, Gorbunov, Nikolai V, Görgülü, Kıvanç, Gorojod, Roxana M, Gorski, Sharon M, Goruppi, Sandro, Gotor, Cecilia, Gottlieb, Roberta A, Gozes, Illana, Gozuacik, Devrim, Graef, Martin, Gräler, Markus H, Granatiero, Veronica, Grasso, Daniel, Gray, Joshua P, Green, Douglas R, Greenhough, Alexander, Gregory, Stephen L, Griffin, Edward F, Grinstaff, Mark W, Gros, Frederic, Grose, Charles, Gross, Angelina S, Gruber, Florian, Grumati, Paolo, Grune, Tilman, Gu, Xueyan, Guan, Jun-Lin, Guardia, Carlos M, Guda, Kishore, Guerra, Flora, Guerri, Consuelo, Guha, Prasun, Guillén, Carlos, Gujar, Shashi, Gukovskaya, Anna, Gukovsky, Ilya, Gunst, Jan, Günther, Andreas, Guntur, Anyonya R, Guo, Chuanyong, Guo, Chun, Guo, Hongqing, Guo, Lian-Wang, Guo, Ming, Gupta, Pawan, Gupta, Shashi Kumar, Gupta, Swapnil, Gupta, Veer Bala, Gupta, Vivek, Gustafsson, Asa B, Gutterman, David D, H.B., Ranjitha, Haapasalo, Annakaisa, Haber, James E, Hać, Aleksandra, Hadano, Shinji, Hafrén, Anders J, Haidar, Mansour, Hall, Belinda S, Halldén, Gunnel, Hamacher-Brady, Anne, Hamann, Andrea, Hamasaki, Maho, Han, Weidong, Hansen, Malene, Hanson, Phyllis I., Hao, Zijian, Harada, Masaru, Harhaji-Trajkovic, Ljubica, Hariharan, Nirmala, Haroon, Nigil, Harris, James, Hasegawa, Takafumi, Hasima Nagoor, Noor, Haspel, Jeffrey A, Haucke, Volker, Hawkins, Wayne D, Hay, Bruce A, Haynes, Cole M, Hayrabedyan, Soren B, Hays, Thomas S, He, Congcong, He, Qin, He, Rong-Rong, He, You-Wen, He, Yu-Ying, Heakal, Yasser, Heberle, Alexander M, Hejtmancik, J Fielding, Helgason, Gudmundur Vignir, Henkel, Vanessa, Herb, Marc, Hergovich, Alexander, Herman-Antosiewicz, Anna, Hernández, Agustín, Hernandez, Carlos, Hernandez-Diaz, Sergio, Hernandez-Gea, Virginia, Herpin, Amaury, Herreros, Judit, Hervás, Javier H, Hesselson, Daniel, Hetz, Claudio, Heussler, Volker T, Higuchi, Yujiro, 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Haining, Zhu, Hongxin, Zhu, Hua, Zhu, Wei-Guo, Zhu, Yanping, Zhu, Yushan, Zhuang, Haixia, Zhuang, Xiaohong, Zientara-Rytter, Katarzyna, Zimmermann, Christine M, Ziviani, Elena, Zoladek, Teresa, Zong, Wei-Xing, Zorov, Dmitry B, Zorzano, Antonio, Zou, Weiping, Zou, Zhen, Zou, Zhengzhi, Zuryn, Steven, Zwerschke, Werner, Brand-Saberi, Beate, Dong, X Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith C, Stallings, Christina L, and Tong, Chun-Kit
Abstract: In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines formonitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a Do not distribute. difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated fromstimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate withmore autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis,whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers tha
Published: 2021

36. History of Vaccines and How They Work

Author: Meng, Xiang-Jin, Rafie, Carlin, Santiago, Vanessa, Wright, LaWanda, Barber, Crystal, Butterfield, Kimberly, Henderson, Jane, Salazar, Aisha, Meng, Xiang-Jin, Rafie, Carlin, Santiago, Vanessa, Wright, LaWanda, Barber, Crystal, Butterfield, Kimberly, Henderson, Jane, and Salazar, Aisha
Published: 2021

37. Hepatitis E Virus in Pigs from Slaughterhouses, United States, 2017-2019

Author: Sooryanarain, Harini, Heffron, C. Lynn, Hill, Dolores E., Fredericks, Jorrell, Rosenthal, Benjamin M., Werre, Stephen R., Opriessnig, Tanja, Meng, Xiang-Jin, Sooryanarain, Harini, Heffron, C. Lynn, Hill, Dolores E., Fredericks, Jorrell, Rosenthal, Benjamin M., Werre, Stephen R., Opriessnig, Tanja, and Meng, Xiang-Jin
Abstract: Hepatitis E virus (HEV) RNA was detected in 6.3% and HEV IgG in 40% of 5,033 serum samples from market-weight pigs at 25 slaughterhouses in 10 US states. The prevalent HEV genotype was zoonotic genotype 3, group 2. Blood of HEV-viremic pigs from slaughterhouses may contaminate pork supply chains.
Published: 2020
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38. The U-Rich Untranslated Region of the Hepatitis E Virus Induces Differential Type I and Type III Interferon Responses in a Host Cell-Dependent Manner

Author: Sooryanarain, Harini, Heffron, C. Lynn, Meng, Xiang-Jin, Sooryanarain, Harini, Heffron, C. Lynn, and Meng, Xiang-Jin
Abstract: Hepatitis E virus (HEV), a single-strand positive-sense RNA virus, is an understudied but important human pathogen. The virus can establish infection at a number of host tissues, including the small intestine and liver, causing acute and chronic hepatitis E as well as certain neurological disorders. The retinoic acid-inducible gene I (RIG-I) pathway is essential to induce the interferon (IFN) response during HEV infection. However, the pathogen-associated motif patterns (PAMPs) in the HEV genome that are recognized by RIG-I remain unknown. In this study, we first identified that HEV RNA PAMPs derived from the 3' untranslated region (UTR) of the HEV genome induced higher levels of IFN mRNA, interferon regulatory factor-3 (IRF3) phosphorylation, and nuclear translocation than the 5' UTR of HEV. We revealed that the U-rich region in the 3' UTR of the HEV genome acts as a potent RIG-I PAMP, while the presence of poly(A) tail in the 3' UTR further increases the potency. We further demonstrated that HEV UTR PAMPs induce differential type I and type III IFN responses in a cell type-dependent fashion. Predominant type III IFN response was observed in the liver tissues of pigs experimentally infected with HEV as well as in HEV RNA PAMP-induced human hepatocytes in vitro. In contrast, HEV RNA PAMPs induced a predominant type I IFN response in swine enterocytes. Taken together, the results from this study indicated that the IFN response during HEV infection depends both on viral RNA motifs and host target cell types. The results have important implications in understanding the mechanism of HEV pathogenesis. IMPORTANCE Hepatitis E virus (HEV) is an important human pathogen causing both acute and chronic viral hepatitis E infection. Currently, the mechanisms of HEV replication and pathogenesis remain poorly understood. The innate immune response acts as the first line of defense during viral infection. The retinoic acid-inducible gene I (RIG-I)-mediated interferon (IFN) response
Published: 2020
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39. Blue Large-Amplitude Pulsators: the Possible Surviving Companions of Type Ia Supernovae

Author: Meng, Xiang-Cun, Han, Zhan-Wen, Podsiadlowski, Philipp, Li, Jiao, Meng, Xiang-Cun, Han, Zhan-Wen, Podsiadlowski, Philipp, and Li, Jiao
Abstract: The single degenerate (SD) model, one of the leading models for the progenitors of Type Ia supernovae (SNe Ia), predicts that there should be binary companions that survive the supernova explosion which, in principle, should be detectable in the Galaxy. The discovery of such surviving companions could therefore provide conclusive support for the SD model. Several years ago, a new type of mysterious variables was discovered, the so-called blue large-amplitude pulsators (BLAPs). Here we show that all the properties of BLAPs can be reasonably well reproduced if they are indeed such surviving companions, in contrast to other proposed channels. This suggests that BLAPs could potentially be the long-sought surviving companions of SNe Ia. Our model also predicts a new channel for forming single hot subdwarf stars, consistent with a small group in the present hot-subdwarf-star sample., Comment: 21 pages, 13 figures, accepted for publication in ApJ
Published: 2020
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40. Testing H0 in Acoustic Dark Energy Models with Planck and ACT Polarization

Author: Lin, Meng-Xiang, Hu, Wayne, Raveri, Marco, Lin, Meng-Xiang, Hu, Wayne, and Raveri, Marco
Abstract: The canonical acoustic dark energy model (cADE), which is based on a scalar field with a canonical kinetic term that rapidly converts potential to kinetic energy around matter radiation equality, alleviates the Hubble tension found in $\Lambda$CDM. We show that it successfully passes new consistency tests in the CMB damping tail provided by the ACT data, while being increasingly constrained and distinguished from alternate mechanisms by the improved CMB acoustic polarization data from Planck. The best fit cADE model to a suite of cosmological observations, including the SH0ES $H_0$ measurement, has $H_0=70.25$ compared with $68.23$ (km s$^{-1}$ Mpc$^{-1}$) in $\Lambda$CDM and a finite cADE component is preferred at the $2.8\sigma$ level. The ability to raise $H_0$ is now mainly constrained by the improved Planck acoustic polarization data, which also plays a crucial role in distinguishing cADE from the wider class of early dark energy models. ACT and Planck TE polarization data are currently mildly discrepant in normalization and drive correspondingly different preferences in parameters. Improved constraints on intermediate scale polarization approaching the cosmic variance limit will be an incisive test of the acoustic dynamics of these models and their alternatives., Comment: v2: Added more references; matched the published version. 10 pages, 8 figures
Published: 2020
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41. To Develop and Validate the Combination of RNA Methylation Regulators for the Prognosis of Patients with Gastric Cancer

Author: Zhang,Jun, Piao,Hai-yan, Wang,Yue, Meng,Xiang-yu, Yang,Dong, Zhao,Yan, Zheng,Zhi-chao, Zhang,Jun, Piao,Hai-yan, Wang,Yue, Meng,Xiang-yu, Yang,Dong, Zhao,Yan, and Zheng,Zhi-chao
Abstract: Jun Zhang,1 Hai-yan Piao,2 Yue Wang,1 Xiang-yu Meng,1 Dong Yang,1 Yan Zhao,1 Zhi-chao Zheng1 1Gastric Cancer Department, Liaoning Province Cancer Hospital & Institute (Cancer Hospital of China Medical University), Shenyang City, Liaoning Province 110042, People’s Republic of China; 2Medical Oncology Department of Gastrointestinal Cancer, Liaoning Province Cancer Hospital & Institute (Cancer Hospital of China Medical University), Shenyang City, Liaoning Province 110042, People’s Republic of ChinaCorrespondence: Zhi-chao Zheng Professor of Gastric Cancer DepartmentLiaoning Province Cancer Hospital and Institute (Cancer Hospital of China Medical University), No. 44 Xiaoheyan Road, Dadong District, Shenyang, Liaoning Province 110042, People’s Republic of ChinaTel +86-24-31916823Fax +86-24-24315679Email zhengzhichao@cancerhosp-ln-cmu.comBackground: Gastric cancer (GC) accounts for high mortality. RNA methylation has recently gained interest as markers in specific tumors. This study aimed to uncover the function of the roles of 25 RNA methylation regulators in GC.Methods: RNA sequence and clinical data were downloaded from The Cancer Genome Atlas (TCGA) database. “STRING” and R were performed to analyze the correlation among the methylase. COX and LASSO were performed to screen for prognostic associated RNA methylation regulators. A prognostic model was established based on the expression of methylase. RT-PCR and immunohistochemistry detected the expression of methylase in GC cells and tissue. Kaplan–Meier curve and Cox analysis were applied to evaluate the effectiveness of the model.Results: The prediction model was established based on the expression of m6A RNA methylation regulators FTO (fat mass and obesity-associated) and RBM15 (RNA binding motif protein 15). Based on the model, GC patients were divided into “high risk” and “low risk” groups to compare
Published: 2020

42. Update: proposed reference sequences for subtypes of hepatitis E virus (species Orthohepevirus A)

Author: Smith, Donald B., Izopet, Jacques, Nicot, Florence, Simmonds, Peter, Jameel, Shahid, Meng, Xiang Jin, Norder, Heléne, Okamoto, Hiroaki, van der Poel, Wim H.M., Reuter, Gábor, Purdy, Michael A., Smith, Donald B., Izopet, Jacques, Nicot, Florence, Simmonds, Peter, Jameel, Shahid, Meng, Xiang Jin, Norder, Heléne, Okamoto, Hiroaki, van der Poel, Wim H.M., Reuter, Gábor, and Purdy, Michael A.
Abstract: In this recommendation, we update our 2016 table of reference sequences of subtypes of hepatitis E virus (HEV; species Orthohepevirus A, family Hepeviridae) for which complete genome sequences are available (Smith et al., 2016). This takes into account subsequent publications describing novel viruses and additional proposals for subtype names; there are now eight genotypes and 36 subtypes. Although it remains difficult to define strict criteria for distinguishing between virus subtypes, and is not within the remit of the International Committee on Taxonomy of Viruses (ICTV), the use of agreed reference sequences will bring clarity and stability to researchers, epidemiologists and clinicians working with HEV.
Published: 2020

43. Curvature Perturbations in the Effective Field Theory of Inflation

Author: Lagos, Macarena, Lin, Meng-Xiang, Hu, Wayne, Lagos, Macarena, Lin, Meng-Xiang, and Hu, Wayne
Abstract: We discuss the difference between various gauge-invariant quantities typically used in single-field inflation, namely synchronous $\zeta_s$, comoving $\zeta_c$, and unitary $\zeta_u$ curvatures. We show that conservation of $\zeta_c$ outside the horizon is quite restrictive on models as it leads to conservation of $\zeta_s$ and $\zeta_u$, whereas the reverse does not hold. We illustrate the consequence of these differences with two inflationary models: ultra-slow-roll (USR) and braiding-ultra-slow-roll (BUSR). In USR, we show that out of the three curvatures, only $\zeta_s$ is conserved outside the horizon, and we connect this result to the concepts of separate universe and the usage of the $\delta N$ formalism. We find that even though $\zeta_s$ is conserved, there is still a mild violation of the separate universe approximation in the continuity equation. Nevertheless, the $\delta N$ formalism can still be applied to calculate the primordial power spectrum of some gauge-invariant quantities such as $\zeta_u$, although it breaks down for others such as the uniform-density curvature. In BUSR, we show that both $\zeta_u$ and $\zeta_s$ are conserved outside the horizon, but take different values. Additionally, since $\zeta_u\not=\zeta_c$ we find that the prediction for observable curvature fluctuations after inflation does not reflect $\zeta_c$ at horizon crossing during inflation and moreover involves not just $\zeta_u$ at that epoch but also the manner in which the braiding phase ends.
Published: 2019
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44. Acoustic Dark Energy: Potential Conversion of the Hubble Tension

Author: Lin, Meng-Xiang, Benevento, Giampaolo, Hu, Wayne, Raveri, Marco, Lin, Meng-Xiang, Benevento, Giampaolo, Hu, Wayne, and Raveri, Marco
Abstract: We discuss the ability of a dark fluid becoming relevant around the time of matter radiation equality to significantly relieve the tension between local measurements of the Hubble constant and CMB inference, within the $\Lambda$CDM model. We show that the gravitational impact of acoustic oscillations in the dark fluid balance the effects on the CMB and result in an improved fit to CMB measurements themselves while simultaneously raising the Hubble constant. The required balance favors a model where the fluid is a scalar field that converts its potential to kinetic energy around matter radiation equality which then quickly redshifts away. We derive the requirements on the potential for this conversion mechanism and find that a simple canonical scalar with two free parameters for its local slope and amplitude robustly improves the fit to the combined data by $\Delta\chi^2 \approx 12.7$ over $\Lambda$CDM. We uncover the CMB polarization signatures that can definitively test this scenario with future data., Comment: v3: matched the published version
Published: 2019
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45. Robust Control Optimization for Quantum Approximate Optimization Algorithm

Author: Dong, Yulong, Meng, Xiang, Lin, Lin, Kosut, Robert, Whaley, K. Birgitta, Dong, Yulong, Meng, Xiang, Lin, Lin, Kosut, Robert, and Whaley, K. Birgitta
Abstract: Quantum variational algorithms have garnered significant interest recently, due to their feasibility of being implemented and tested on noisy intermediate scale quantum (NISQ) devices. We examine the robustness of the quantum approximate optimization algorithm (QAOA), which can be used to solve certain quantum control problems, state preparation problems, and combinatorial optimization problems. We demonstrate that the error of QAOA simulation can be significantly reduced by robust control optimization techniques, specifically, by sequential convex programming (SCP), to ensure error suppression in situations where the source of the error is known but not necessarily its magnitude. We show that robust optimization improves both the objective landscape of QAOA as well as overall circuit fidelity in the presence of coherent errors and errors in initial state preparation., Comment: 8 pages, 4 figures
Published: 2019

46. Adaptive Robot-Assisted Feeding: An Online Learning Framework for Acquiring Previously Unseen Food Items

Author: Gordon, Ethan K., Meng, Xiang, Barnes, Matt, Bhattacharjee, Tapomayukh, Srinivasa, Siddhartha S., Gordon, Ethan K., Meng, Xiang, Barnes, Matt, Bhattacharjee, Tapomayukh, and Srinivasa, Siddhartha S.
Abstract: A successful robot-assisted feeding system requires bite acquisition of a wide variety of food items. It must adapt to changing user food preferences under uncertain visual and physical environments. Different food items in different environmental conditions require different manipulation strategies for successful bite acquisition. Therefore, a key challenge is how to handle previously unseen food items with very different success rate distributions over strategy. Combining low-level controllers and planners into discrete action trajectories, we show that the problem can be represented using a linear contextual bandit setting. We construct a simulated environment using a doubly robust loss estimate from previously seen food items, which we use to tune the parameters of off-the-shelf contextual bandit algorithms. Finally, we demonstrate empirically on a robot-assisted feeding system that, even starting with a model trained on thousands of skewering attempts on dissimilar previously seen food items, $\epsilon$-greedy and LinUCB algorithms can quickly converge to the most successful manipulation strategy., Comment: To appear in IROS 2020; 8 pages incl. references, 8 figures; Abstract presented in IJCAI 2019 AIxFood Workshop; v3: Added simulation and experimental results for conference submission; v4: Added extra results to Experiment 2 for camera-ready submission
Published: 2019

47. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof

Author: Virginia Tech Intellectual Properties, Inc., Iowa State University Research Foundation, Inc., Halbur, Patrick G., Meng, Xiang-Jin, Fenaux, Martijn, Virginia Tech Intellectual Properties, Inc., Iowa State University Research Foundation, Inc., Halbur, Patrick G., Meng, Xiang-Jin, and Fenaux, Martijn
Abstract: The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone and its derived, avirulent chimeric virus are constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position. The chimeric virus advantageously retains the nonpathogenic phenotype of PCV1 but elicits specific immune responses against the pathogenic PCV2. The invention further embraces the immunogenic polypeptide expression products. In addition, the invention encompasses two mutations in the PCV2 immunogenic capsid gene and protein, and the introduction of the ORF2 mutations in the chimeric clones.
Published: 2019

48. Phenomenology of Modified Gravity at Recombination

Author: Lin, Meng-Xiang, Raveri, Marco, Hu, Wayne, Lin, Meng-Xiang, Raveri, Marco, and Hu, Wayne
Abstract: We discuss the phenomenological imprints of modifications to gravity in the early universe with a specific focus on the time of recombination. We derive several interesting results regarding the effect that such modifications have on cosmological observables, especially on the driving and phasing of acoustic oscillations, observed in the CMB and BAO, as well as the weak gravitational lensing of the CMB and of galaxy shapes. This widens the pool of measurements that can be used to test gravity with present and future surveys, in particular realizing the full constraining power of the structure of the primary peaks of the CMB spectrum. We investigate whether such a phenomenology can relax tensions between cosmological measurements and find that a modification of the gravitational constant at recombination would help in reconciling measurements of the CMB with local measurements of the Hubble constant., Comment: 22 pages, 21 figures
Published: 2018
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49. Infectious genomic DNA clone and serological profile of torque teno sus virus 1 and 2

Author: Meng, Xiang-Jin, Huang, Yaowei, Meng, Xiang-Jin, and Huang, Yaowei
Abstract: The present invention also provides infectious DNA clones, biologically functional plasmid or viral vector containing the infectious nucleic acid genome molecule of Torque teno sus virus (TTsuV). The present invention also provides methods for diagnosing TTsuV infection via immunological methods, e.g., enzyme-linked immunoabsorbent assay (ELISA) and Western blot using PTTV specific antigens for detecting serum PTTV specific antibodies which indicate infections TTsuV1, TTsuV2, and individual TTsuV1 genotypes.
Published: 2018

50. Live attenuated chimeric porcine circovirus vaccine

Author: Meng, Xiang-Jin, Beach, Nathan M., Ramamoorthy, Sheela, Meng, Xiang-Jin, Beach, Nathan M., and Ramamoorthy, Sheela
Abstract: The present invention provides a novel chimeric porcine circovirus infectious DNA clone and live attenuated chimeric virus with the PCV2, preferably of subtype PCV2b, capsid gene integrated into a non-pathogenic PCV1 virus genome. In a particular embodiment, the PCV2 capids gene is of subtype PCV2b, the predominant subtype circulating in pigs worldwide. The attenuated chimeric virus, designated PCV1-2b, effectively protects pigs from PCV2b challenges, and can be used as a live vaccine, as well as an inactivated (killed) vaccine, that provides protection and cross protection against PCV2b and PCV2a subtypes infection. The live attenuated vaccine of the present invention is also effective protecting pigs from porcine circovirus-associated disease (PCVAD).
Published: 2018

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