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Višestruke metastaze melanoma kože predstavljaju problem u liječenju, pogotovo u centrima koji ne raspolažu perfuzijom izoliranih organa. Predstavljamo slučaj žene u dobi od 59 godina u koje su se razvile višestruke male neoperabilne metastaze melanoma kože na bedru nakon što joj je amputiran donji dio noge. lektrokemoterapijom bleomicinom postignuti su dobri rezultati u lokalnom suzbijanju bolesti, s potpunim odgovorom liječenih čvorića melanoma (224 čvorića) nakon 4 navrata liječenja. Elektrokemoterapija frekvencije ponavljanja električnog pulsa od 1 Hz i frekvencije električnog pulsa od 5 Hz pokazala je jednaku učinkovitost u suzbijanju tumora. Elektrokemoterapija s intravenoznim bleomicinom može se rabiti kao postupak izbora za lokalno suzbijanje metastaza neoperabilnog melanoma kože., Multiple unresectable melanoma skin metastases pose a treatment problem, especially in centers where isolated limb perfusion is not available. We report the case of a 59-year-old woman who developed multiple small unresectable cutaneous melanoma metastases on the thigh after her lower limb was amputated. Electrochemotherapy with bleomycin resulted in good local control of the disease, with a complete response of the treated melanoma nodules (224 tumor nodules) after 4 treatment sessions. Comparison between electrochemotherapy using repetition frequency of the applied electric pulses of 1 Hz and 5 kHz demonstrated equal antitumor effectiveness. Electrochemotherapy with intravenous bleomycin can also be used as a treatment of choice for local control of multiple unresectable cutaneous melanoma skin metastases

Višestruke metastaze melanoma kože predstavljaju problem u liječenju, pogotovo u centrima koji ne raspolažu perfuzijom izoliranih organa. Predstavljamo slučaj žene u dobi od 59 godina u koje su se razvile višestruke male neoperabilne metastaze melanoma kože na bedru nakon što joj je amputiran donji dio noge. lektrokemoterapijom bleomicinom postignuti su dobri rezultati u lokalnom suzbijanju bolesti, s potpunim odgovorom liječenih čvorića melanoma (224 čvorića) nakon 4 navrata liječenja. Elektrokemoterapija frekvencije ponavljanja električnog pulsa od 1 Hz i frekvencije električnog pulsa od 5 Hz pokazala je jednaku učinkovitost u suzbijanju tumora. Elektrokemoterapija s intravenoznim bleomicinom može se rabiti kao postupak izbora za lokalno suzbijanje metastaza neoperabilnog melanoma kože., Multiple unresectable melanoma skin metastases pose a treatment problem, especially in centers where isolated limb perfusion is not available. We report the case of a 59-year-old woman who developed multiple small unresectable cutaneous melanoma metastases on the thigh after her lower limb was amputated. Electrochemotherapy with bleomycin resulted in good local control of the disease, with a complete response of the treated melanoma nodules (224 tumor nodules) after 4 treatment sessions. Comparison between electrochemotherapy using repetition frequency of the applied electric pulses of 1 Hz and 5 kHz demonstrated equal antitumor effectiveness. Electrochemotherapy with intravenous bleomycin can also be used as a treatment of choice for local control of multiple unresectable cutaneous melanoma skin metastases

In the article are collected the Slovene and Croatian surnames ending in -goj and their Italianized variant -goi, as well as part of the medieval attestations of anthroponyms in historical registers with this morpheme that helps to shed light on its primary semantic value. The identification of this morpheme with the Common Slavic lexeme *gojb, whose meaning can be established using the comparative method as diving, vocation', is obvious. (...), Članek prinaša vse današnje sloven. in hrv. priimke na -goj in -goi. Z uporabo primerjalne metode predlaga etimološke reŠitve priimkov Čeligoj, Sali goj, Šeligo in Šeliga ter listinsko izpričanih srednjeveŠkih antroponimov Zwerigoy < *Zvérigojb, Porgoy < *Borigojb, Sitigoi < *Žitigojb in Domagoy < *Domagojb.