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In genetic causes of male infertility, Y chromosome microdeletions are the second most common after Klinefelter’s syndrome. Although sperm recovery rate is relatively high for subjects with azoospermic factor (AZF) c chromosome microdeletion, intracytoplasmic sperm injection (ICSI) results using retrieved sperm has been reported to be poor. We retrospectively examined the infertility treatment for subjects with AZF microdeletion. From October 2017 to September 2020, chromosomal examination of 67 azoospermic subjects and 12 cryptozoospermia were performed. Of these, twenty-three subjects (29.1%) had AZF microdeletion. Twelve subjects with AZFc microdeletion and one subtype with unknown classification (Ym-9; P3 deletion) received sperm retrieval surgery due to azoospermia. Two subjects obtained motile sperm by microscopic epididymal sperm aspiration (MESA) and four subjects by microscopic testicular sperm extraction (micro-TESE). Pregnancy and healthy delivery were achieved in 6 of 14 subject (42.9%; including one twin) using ICSI. This was comparable with previous reports. Since there were two cases of obstructive azoospermia, we employed MESA to avoid testicular damage. Following observation of the testis and epididymis under operative microscope, a decision was made to perform sperm retrieval surgery to avoid unnecessary testicular damage. Furthermore, since AZFc microdeletion is passed to the next generation, long term follow-up is necessary., This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).

In genetic causes of male infertility, Y chromosome microdeletions are the second most common after Klinefelter’s syndrome. Although sperm recovery rate is relatively high for subjects with azoospermic factor (AZF) c chromosome microdeletion, intracytoplasmic sperm injection (ICSI) results using retrieved sperm has been reported to be poor. We retrospectively examined the infertility treatment for subjects with AZF microdeletion. From October 2017 to September 2020, chromosomal examination of 67 azoospermic subjects and 12 cryptozoospermia were performed. Of these, twenty-three subjects (29.1%) had AZF microdeletion. Twelve subjects with AZFc microdeletion and one subtype with unknown classification (Ym-9; P3 deletion) received sperm retrieval surgery due to azoospermia. Two subjects obtained motile sperm by microscopic epididymal sperm aspiration (MESA) and four subjects by microscopic testicular sperm extraction (micro-TESE). Pregnancy and healthy delivery were achieved in 6 of 14 subject (42.9%; including one twin) using ICSI. This was comparable with previous reports. Since there were two cases of obstructive azoospermia, we employed MESA to avoid testicular damage. Following observation of the testis and epididymis under operative microscope, a decision was made to perform sperm retrieval surgery to avoid unnecessary testicular damage. Furthermore, since AZFc microdeletion is passed to the next generation, long term follow-up is necessary., This is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (http://creativecommons.org/licenses/by-nc-nd/4.0/).

La mesa se construye mediante seis tableros formados por planos horizontales de MDF de 4mm. separados 38mm por una cuadrícula de costillas verticales de 3mm. Se optimizan acudiendo al control numérico. Un tablero, por sí solo, construye la parte móvil de la mesa. Los otros cinco, ensamblados en seco, la parte fija. Para la unión de los tableros, se proyecta una galleta en DM que se sitúa en la parte central de cada plano. Un ligero desplazamiento horizontal ensambla los dos tableros. Cuando esto ocurre, una pata de forma trapezoidal, también en DM se introduce por la parte inferior, para permitir el apoyo de los dos planos en el sentido “X”. Acto seguido dos piezas clave en forma de “C” fijan por la parte superior la pata a los tableros. Finalmente, una cruceta del mismo material encaja transversalmente con la pata formando una “T” que absorbe los movimientos en “Y”. La cruceta se fija a la pata mediante dos piezas rectangulares de madera de pino. El cambio de material persigue dejar latente el proceso de montaje. Entre patas en forma de “T”, se disponen patas redondas de 60mm, reducidas a 50mm al llegar al suelo y al tablero; al suelo, para aligerar la superficie de contacto; al plano, para construir un último apoyo en seco. Cruz, punto, cruz, punto, es el ritmo que se repite a lo largo del tramo fijo. El tramo móvil, de un solo tablero, prescinde la cruz, destinada a la unión de tableros, precisando tan solo el punto. La mesa, se expande al resto del escenario en forma de armarios, puertas y estanterías. Estas últimas apoyadas tan solo sobre una barra corrugada de 16mm fijada a la pared mediante un taco químico, que sirve a su vez de perchero. Al contrario, el resto de mobiliario, intencionadamente, se viste de color blanco. Se persigue que no ocupen visualmente el espacio. Que desaparezcan en el escenario. Pues, en realidad, la mesa es el despacho., Postprint (published version)

[ES] Este proyecto presenta la creación de una familia de mobiliario (mesas) multifuncional y creativa basada en el concepto y la forma de la Luna. El desarrollo del proyecto contempla: los diseños técnicos, 3D, planos y maqueta. Además se llevará a cabo el diseño de la campaña publicitaria, mediante un vídeo y carteles que transmitan el mensaje deseado. El objetivo es crear una colección de muebles sostenible, funcional y estética., [EN] This project presents the creation of a family of furniture (tables) that are based on the concept of the Moon, are multifunctional and creative. During the development of the project has been: the technical designs, 3D, plans and mock-up will be carried out. In addition, the design of the advertising campaign will be carried out, by means of a video and posters that transmit the desired message. The aim is to create a sustainable, functional and aesthetic furniture collection.

[ES] Este proyecto presenta la creación de una familia de mobiliario (mesas) multifuncional y creativa basada en el concepto y la forma de la Luna. El desarrollo del proyecto contempla: los diseños técnicos, 3D, planos y maqueta. Además se llevará a cabo el diseño de la campaña publicitaria, mediante un vídeo y carteles que transmitan el mensaje deseado. El objetivo es crear una colección de muebles sostenible, funcional y estética., [EN] This project presents the creation of a family of furniture (tables) that are based on the concept of the Moon, are multifunctional and creative. During the development of the project has been: the technical designs, 3D, plans and mock-up will be carried out. In addition, the design of the advertising campaign will be carried out, by means of a video and posters that transmit the desired message. The aim is to create a sustainable, functional and aesthetic furniture collection.

[ES] Este proyecto presenta la creación de una familia de mobiliario (mesas) multifuncional y creativa basada en el concepto y la forma de la Luna. El desarrollo del proyecto contempla: los diseños técnicos, 3D, planos y maqueta. Además se llevará a cabo el diseño de la campaña publicitaria, mediante un vídeo y carteles que transmitan el mensaje deseado. El objetivo es crear una colección de muebles sostenible, funcional y estética., [EN] This project presents the creation of a family of furniture (tables) that are based on the concept of the Moon, are multifunctional and creative. During the development of the project has been: the technical designs, 3D, plans and mock-up will be carried out. In addition, the design of the advertising campaign will be carried out, by means of a video and posters that transmit the desired message. The aim is to create a sustainable, functional and aesthetic furniture collection.

Background and aimsWe aimed to determine the utility of coronary artery calcium (CAC) for atherosclerotic cardiovascular disease (ASCVD) risk stratification in women with and without early menopause (EM).MethodsTo examine the association between CAC and incident ASCVD, we performed Kaplan-Meier survival analysis and multivariable Cox proportional hazards modeling using data from 2,456 postmenopausal women in the Multi-Ethnic Study of Atherosclerosis (MESA) with or without EM, defined as occurring at <45 years of age.ResultsThe cohort was 64.1 ± 9.1 years old and 28.0% experienced EM. There were 291 ASCVD events over 12.5 ± 3.6 year follow-up with a higher event rate among those with EM compared to those without EM of 13.6 vs. 9.0 per 1,000 year follow-up (p < 0.01). Women with EM had a slightly lower prevalence of CAC = 0 (55.1%) than women without EM (59.7%) (p = 0.04) despite no difference in mean age. Among women with CAC = 0, the cumulative incidence of ASCVD at 10 years was low-to-borderline for women with (5.4%) and without EM (3.2%) (p = 0.06). However, women with EM had a significantly higher 15-year risk with an adjusted HR of 1.96 (95% CI: 1.26-3.04). In multivariable Cox models, women with CAC ≥ 1 had progressively increased ASCVD risk that did not significantly differ by EM status.ConclusionIn MESA, >50% of middle-aged postmenopausal women with EM had CAC = 0, similar to those without EM. Among women with CAC = 0, those with EM had a low to borderline 10-year risk of ASCVD, but the 15-year risk was significantly higher for women with EM versus those without EM. When CAC ≥ 1, the incidence of ASCVD was similar for women with and without EM. These findings support the use of CAC to help improve ASCVD risk stratification in women with EM.Condensed abstractThis study investigated the association between coronary artery calcium (CAC) and incident atherosclerotic card

Agent-based modeling is a simulation method in which autonomous agents interact with their environment and one another, given a predefined set of rules. It is an integral method for modeling and simulating complex systems, such as socio-economic problems. Since agent-based models are not described by simple and concise mathematical equations, the code that generates them is typically complicated, large, and slow. Here we present Agents.jl, a Julia-based software that provides an ABM analysis platform with minimal code complexity. We compare our software with some of the most popular ABM software in other programming languages. We find that Agents.jl is not only the most performant but also the least complicated software, providing the same (and sometimes more) features as the competitors with less input required from the user. Agents.jl also integrates excellently with the entire Julia ecosystem, including interactive applications, differential equations, parameter optimization, and so on. This removes any extensions library requirement from Agents.jl, which is paramount in many other tools.

Background and aimsWe aimed to determine the utility of coronary artery calcium (CAC) for atherosclerotic cardiovascular disease (ASCVD) risk stratification in women with and without early menopause (EM).MethodsTo examine the association between CAC and incident ASCVD, we performed Kaplan-Meier survival analysis and multivariable Cox proportional hazards modeling using data from 2,456 postmenopausal women in the Multi-Ethnic Study of Atherosclerosis (MESA) with or without EM, defined as occurring at <45 years of age.ResultsThe cohort was 64.1 ± 9.1 years old and 28.0% experienced EM. There were 291 ASCVD events over 12.5 ± 3.6 year follow-up with a higher event rate among those with EM compared to those without EM of 13.6 vs. 9.0 per 1,000 year follow-up (p < 0.01). Women with EM had a slightly lower prevalence of CAC = 0 (55.1%) than women without EM (59.7%) (p = 0.04) despite no difference in mean age. Among women with CAC = 0, the cumulative incidence of ASCVD at 10 years was low-to-borderline for women with (5.4%) and without EM (3.2%) (p = 0.06). However, women with EM had a significantly higher 15-year risk with an adjusted HR of 1.96 (95% CI: 1.26-3.04). In multivariable Cox models, women with CAC ≥ 1 had progressively increased ASCVD risk that did not significantly differ by EM status.ConclusionIn MESA, >50% of middle-aged postmenopausal women with EM had CAC = 0, similar to those without EM. Among women with CAC = 0, those with EM had a low to borderline 10-year risk of ASCVD, but the 15-year risk was significantly higher for women with EM versus those without EM. When CAC ≥ 1, the incidence of ASCVD was similar for women with and without EM. These findings support the use of CAC to help improve ASCVD risk stratification in women with EM.Condensed abstractThis study investigated the association between coronary artery calcium (CAC) and incident atherosclerotic card

BackgroundAortic arch calcium (AAC), which is frequently detected on ungated lung computed tomography (CT) due to a large field of view, can serve as a marker of subclinical atherosclerotic burden. Our study sought to validate novel cardiac screening metrics of subclinical atherosclerosis by evaluating the inter- and intra-observer reproducibility of AAC measurements with ungated lung CT.MethodsThe authors randomly selected 100 ungated lung CT scans from the Multi-Ethnic Study of Atherosclerosis cohort. A Bland-Altman plot analysis was used to test inter- and intra-reader reproducibility, after measuring the total arch calcium score and arch calcium volume.ResultsThe intra-reader reproducibility for the total arch calcium score and arch calcium volume in all subjects was excellent at 99% and 97%, respectively. The inter-reader reproducibility for the total arch calcium score and volume in all subjects was similarly excellent at 97% and 96%, respectively.ConclusionsThe high reproducibility of ungated lung CT suggests a potential new method of stratifying the atherosclerotic cardiovascular disease risk among patients undergoing lung CT without requiring additional scanning. This methodology helps promote routine reporting of AAC and coronary artery calcium based on millions of ungated CT images acquired for lung screening purposes.

Polarized growth is a defining property of filamentous fungi, which plays an important role in different aspects of their biology, including virulence. However, little information is available about the determinants of cell surface organization and their role in polarized growth. The fungal protein MesA was identified in a genetic screen in Aspergillus nidulans and is involved in the stabilization of the polarity axes, but it has no evident role in budding yeast. In this work, I present evidence that in the dimorphic fungal phytopathogen Ustilago maydis MesA/Mes1 is involved in cell wall stability and polarized growth. mes1 mutants were more sensitive to drugs provoking cell wall stress, and they displayed a temperature-sensitive phenotype. Actin cytoskeleton was disorganized in a mes1 mutant, suggesting that there is a connection between Mes1, the actin cytoskeleton and polarized morphogenesis. The septin ring was also absent from the bud tip, but not the bud neck. Deletion of mes1 provoked defects in endocytosis and vacuolar organization in the cells. Mes1 was essential for strong polarized growth in the hyphal form, but it was dispensable during low or moderate polarized growth in the yeast form in U. maydis at a permissive temperature. Consistently, mes1 mutants showed delayed mating and they were avirulent.

Polarized growth is a defining property of filamentous fungi, which plays an important role in different aspects of their biology, including virulence. However, little information is available about the determinants of cell surface organization and their role in polarized growth. The fungal protein MesA was identified in a genetic screen in Aspergillus nidulans and is involved in the stabilization of the polarity axes, but it has no evident role in budding yeast. In this work, I present evidence that in the dimorphic fungal phytopathogen Ustilago maydis MesA/Mes1 is involved in cell wall stability and polarized growth. mes1 mutants were more sensitive to drugs provoking cell wall stress, and they displayed a temperature-sensitive phenotype. Actin cytoskeleton was disorganized in a mes1 mutant, suggesting that there is a connection between Mes1, the actin cytoskeleton and polarized morphogenesis. The septin ring was also absent from the bud tip, but not the bud neck. Deletion of mes1 provoked defects in endocytosis and vacuolar organization in the cells. Mes1 was essential for strong polarized growth in the hyphal form, but it was dispensable during low or moderate polarized growth in the yeast form in U. maydis at a permissive temperature. Consistently, mes1 mutants showed delayed mating and they were avirulent.

[ES] Este proyecto se basa en el diseño de la mesa multifunción ¿Duplo¿ . Es una mesa concebida para restaurantes, con la idea de aprovechar mejor el espacio. En ocasiones, sobre todo en zonas de trabajo, la gente acude a comer al restaurante sola. Nos encontramos con un problema de que aunque coloquemos a esta persona en una mesa para dos, perdemos una plaza. Esta mesa te permite mediante un mecanismo una división para que puedan comer dos personas desconocidas en una misma mesa. Es algo que también podría ser útil para establecer separaciones acordes a las recomendaciones sanitarias, tan necesarias en estos tiempos que nos encontramos. A lo anterior descrito, le sumariamos la capacidad de que sea totalmente plegable y pueda combinarse con otras mesas ¿Duplo¿ y formar estaciones de trabajo (puestos para atención de clientes) o de estudios (escuelas, etc)., [EN] his project is based on the design of the ¿Duplo¿ multifunction table. It is a table conceived for restaurants, with the idea of ¿¿making better use of space. Sometimes, especially in work areas, people go to eat at the restaurant alone. We run into a problem that even if we place this person at a table for two, we lose a seat. This table allows you by means of a mechanism a division so that two unknown people can eat at the same table. It is something that could also be useful to establish separations according to the sanitary recommendations, so necessary in these times that we find ourselves. To the above described, we add the ability to be fully foldable and can be combined with other "Duplo" tables and form work stations (customer service stations) or study stations (schools, etc.).

In this brief, a high-performance quasi-vertical GaN Schottky barrier diode (SBD) on sapphire substrate with post-mesa nitridation process is reported, featuring a low damaged sidewall with extremely low leakage current. The fabricated SBD with a drift layer of 1 μm has achieved a very high ON/OFF current ratio (Iscriptscriptstyle ON/Iscriptscriptstyle OFF of 1012 with a low leakage current of ∼ 10-9 A/cm2@-10 V, high forward current density of 5.2 kA/cm2 at 3 V in dc, a low differential specific ON-resistance (Rscriptscriptstyle ONsp) of 0.3 m Ω cm2, and ideality factor of 1.04. In addition, a transmission-line-pulse (TLP) I-V test was carried out and 53 kA/cm2 at 30 V in pulsed measurement was obtained without device failure, exhibiting a great potential for high power applications., Electronic Components, Technology and Materials

ObjectiveThe Miami Heart Study (MiHeart) at Baptist Health South Florida is an ongoing, community-based, prospective cohort study aimed at characterizing the prevalence, characteristics, and prognostic value of diverse markers of early subclinical coronary atherosclerosis and of various potential demographic, psychosocial, and metabolic risk factors. We present the study objectives, detailed research methods, and preliminary baseline results of MiHeart.MethodsMiHeart enrolled 2,459 middle-aged male and female participants from the general population of the Greater Miami Area. Enrollment occurred between May 2015 and September 2018 and was restricted to participants aged 40-65 years free of clinical cardiovascular disease (CVD). The baseline examination included assessment of demographics, lifestyles, medical history, and a detailed evaluation of psychosocial characteristics; a comprehensive physical exam; measurement of multiple blood biomarkers including measures of inflammation, advanced lipid testing, and genomics; assessment of subclinical coronary atherosclerotic plaque and vascular function using coronary computed tomography angiography, the coronary artery calcium score, carotid intima-media thickness, pulse wave velocity, and peripheral arterial tonometry; and other tests including 12-lead electrocardiography and assessment of pulmonary function. Blood samples were biobanked to facilitate future ancillary research.ResultsMiHeart enrolled 1,261 men (51.3%) and 1,198 women (48.7%). Mean age was 53 years, 85.6% participants were White and 47.4% were of Hispanic/Latino ethnicity. The study included 7% individuals with diabetes, 33% with hypertension, and 15% used statin therapy at baseline. Overweight or obese participants comprised 72% of the population and 3% were smokers. Median 10-year estimated atherosclerotic CVD risk using the Pooled Cohort Equations was 4%.ConclusionMiHeart will provide important, novel insights into the pathophysiology of early subclini

[CA] El objecte d’aquest treball de fi de grau és el disseny d’un conjunt de taula i seients dirigit a optimitzar l’espai. La idea sorgeix a partir de les continues noticies sobre l’encariment del preu del lloguer de la vivenda i el augment de l’edat d’emancipació dels joves. Es buscarà dissenyar un moble auxiliar, destinat a joves, que ocupe poc d’espai quan no s’estiga utilitzant, i que es puga transportar amb relativa facilitat. Per a realitzar aquest producte s’estudiaran els referents tècnics i estètics que puguen aportar al projecte, així com les demandes i requeriments dels usuaris. Aquest últim apartat es realitzarà mitjançant enquestes., [ES] L¿objectiu del projecte es el disseny d¿un conjunt de taula i seients dirigit a optimitzar l¿espai per a habitatges d¿us compartit. El projecte inclourà el disseny conceptual, el disseny de detall, el plec de condicions, pressupost i planimetria El objeto del proyecto es el diseño de un conjunto de mesa y asientos dirigido a optimizar el espacio para viviendas de uso compartido. El proyecto abarcará desde el diseño conceptual, al diseño de detalle, pliego de condiciones, presupuesto y planimetría., [EN] The objective of this final degree project is the design of a set of tables and seats focused on optimizing space. The idea arose from the constant news about the rise of the rental and the increase of the age of emancipation. The main objective of that project will be the design of an ancillary piece of furniture that has the less size possible while it is not using, and that can be easily carried. To design that product, the technical and aesthetics referents are going to be studied. The customers’ requirements and demands are going to be studied too, trough surveys.

[ES] Este proyecto se basa en el diseño de la mesa multifunción ¿Duplo¿ . Es una mesa concebida para restaurantes, con la idea de aprovechar mejor el espacio. En ocasiones, sobre todo en zonas de trabajo, la gente acude a comer al restaurante sola. Nos encontramos con un problema de que aunque coloquemos a esta persona en una mesa para dos, perdemos una plaza. Esta mesa te permite mediante un mecanismo una división para que puedan comer dos personas desconocidas en una misma mesa. Es algo que también podría ser útil para establecer separaciones acordes a las recomendaciones sanitarias, tan necesarias en estos tiempos que nos encontramos. A lo anterior descrito, le sumariamos la capacidad de que sea totalmente plegable y pueda combinarse con otras mesas ¿Duplo¿ y formar estaciones de trabajo (puestos para atención de clientes) o de estudios (escuelas, etc)., [EN] his project is based on the design of the ¿Duplo¿ multifunction table. It is a table conceived for restaurants, with the idea of ¿¿making better use of space. Sometimes, especially in work areas, people go to eat at the restaurant alone. We run into a problem that even if we place this person at a table for two, we lose a seat. This table allows you by means of a mechanism a division so that two unknown people can eat at the same table. It is something that could also be useful to establish separations according to the sanitary recommendations, so necessary in these times that we find ourselves. To the above described, we add the ability to be fully foldable and can be combined with other "Duplo" tables and form work stations (customer service stations) or study stations (schools, etc.).

[ES] En el sector del mueble la necesidad de nuevos diseños es constante. En el siguiente proyecto se expone el desarrollo de un set de mesas auxiliares. El objetivo es ofrecer a los posibles consumidores, una combinación de funcionalidad, versatilidad y diseño. Con este objetivo, se realizará un estudio de mercado, analizando los diferentes estilos y diseños existentes. Con los resultados de este estudio se establecerán las características del nuevo diseño. Se propondrán varias soluciones a través de bocetos que conducirán al diseño definitivo. El diseño irá acompañado de representaciones y renderizados para mostrar el resultado final en diferentes ambientes. Además, se propondrá un método de fabricación y los distintos tipos de materiales a utilizar. Todo el proyecto irá acompañado de planos, despieces, representaciones, estudio de normativa y aquellos documentos requeridos para poder desarrollar el producto. La memoria se cerrará con un presupuesto de fabricación para una tirada definida en el pliego de condiciones., [EN] Many reports foresee a progressive growth in the furniture sector, so the need for new designs is constant in this sector. That is why, in the following project, the development of a set of auxiliary tables for all types of environments is exposed. The aim is to offer potential consumers a combination of functionality, versatility and design at the same time, taking into account the need for space reduction that exists today. With this objective, it has begun with a market study, analysing the different styles and existing designs and thus obtaining conclusions on what customers prevail today. Subsequently, the characteristics and properties that the new design must have been established and a multitude of sketches have been carried out. The final sketches will be made using 3D software and rendered to see the final result in different environments. In addition, the manufacturing method and the different types of materials used for its manufacture will be exposed.

[CA] El objecte d’aquest treball de fi de grau és el disseny d’un conjunt de taula i seients dirigit a optimitzar l’espai. La idea sorgeix a partir de les continues noticies sobre l’encariment del preu del lloguer de la vivenda i el augment de l’edat d’emancipació dels joves. Es buscarà dissenyar un moble auxiliar, destinat a joves, que ocupe poc d’espai quan no s’estiga utilitzant, i que es puga transportar amb relativa facilitat. Per a realitzar aquest producte s’estudiaran els referents tècnics i estètics que puguen aportar al projecte, així com les demandes i requeriments dels usuaris. Aquest últim apartat es realitzarà mitjançant enquestes., [ES] L¿objectiu del projecte es el disseny d¿un conjunt de taula i seients dirigit a optimitzar l¿espai per a habitatges d¿us compartit. El projecte inclourà el disseny conceptual, el disseny de detall, el plec de condicions, pressupost i planimetria El objeto del proyecto es el diseño de un conjunto de mesa y asientos dirigido a optimizar el espacio para viviendas de uso compartido. El proyecto abarcará desde el diseño conceptual, al diseño de detalle, pliego de condiciones, presupuesto y planimetría., [EN] The objective of this final degree project is the design of a set of tables and seats focused on optimizing space. The idea arose from the constant news about the rise of the rental and the increase of the age of emancipation. The main objective of that project will be the design of an ancillary piece of furniture that has the less size possible while it is not using, and that can be easily carried. To design that product, the technical and aesthetics referents are going to be studied. The customers’ requirements and demands are going to be studied too, trough surveys.

[ES] En el sector del mueble la necesidad de nuevos diseños es constante. En el siguiente proyecto se expone el desarrollo de un set de mesas auxiliares. El objetivo es ofrecer a los posibles consumidores, una combinación de funcionalidad, versatilidad y diseño. Con este objetivo, se realizará un estudio de mercado, analizando los diferentes estilos y diseños existentes. Con los resultados de este estudio se establecerán las características del nuevo diseño. Se propondrán varias soluciones a través de bocetos que conducirán al diseño definitivo. El diseño irá acompañado de representaciones y renderizados para mostrar el resultado final en diferentes ambientes. Además, se propondrá un método de fabricación y los distintos tipos de materiales a utilizar. Todo el proyecto irá acompañado de planos, despieces, representaciones, estudio de normativa y aquellos documentos requeridos para poder desarrollar el producto. La memoria se cerrará con un presupuesto de fabricación para una tirada definida en el pliego de condiciones., [EN] Many reports foresee a progressive growth in the furniture sector, so the need for new designs is constant in this sector. That is why, in the following project, the development of a set of auxiliary tables for all types of environments is exposed. The aim is to offer potential consumers a combination of functionality, versatility and design at the same time, taking into account the need for space reduction that exists today. With this objective, it has begun with a market study, analysing the different styles and existing designs and thus obtaining conclusions on what customers prevail today. Subsequently, the characteristics and properties that the new design must have been established and a multitude of sketches have been carried out. The final sketches will be made using 3D software and rendered to see the final result in different environments. In addition, the manufacturing method and the different types of materials used for its manufacture will be exposed.

[ES] Este proyecto se basa en el diseño de la mesa multifunción ¿Duplo¿ . Es una mesa concebida para restaurantes, con la idea de aprovechar mejor el espacio. En ocasiones, sobre todo en zonas de trabajo, la gente acude a comer al restaurante sola. Nos encontramos con un problema de que aunque coloquemos a esta persona en una mesa para dos, perdemos una plaza. Esta mesa te permite mediante un mecanismo una división para que puedan comer dos personas desconocidas en una misma mesa. Es algo que también podría ser útil para establecer separaciones acordes a las recomendaciones sanitarias, tan necesarias en estos tiempos que nos encontramos. A lo anterior descrito, le sumariamos la capacidad de que sea totalmente plegable y pueda combinarse con otras mesas ¿Duplo¿ y formar estaciones de trabajo (puestos para atención de clientes) o de estudios (escuelas, etc)., [EN] his project is based on the design of the ¿Duplo¿ multifunction table. It is a table conceived for restaurants, with the idea of ¿¿making better use of space. Sometimes, especially in work areas, people go to eat at the restaurant alone. We run into a problem that even if we place this person at a table for two, we lose a seat. This table allows you by means of a mechanism a division so that two unknown people can eat at the same table. It is something that could also be useful to establish separations according to the sanitary recommendations, so necessary in these times that we find ourselves. To the above described, we add the ability to be fully foldable and can be combined with other "Duplo" tables and form work stations (customer service stations) or study stations (schools, etc.).

ObjectiveThe Miami Heart Study (MiHeart) at Baptist Health South Florida is an ongoing, community-based, prospective cohort study aimed at characterizing the prevalence, characteristics, and prognostic value of diverse markers of early subclinical coronary atherosclerosis and of various potential demographic, psychosocial, and metabolic risk factors. We present the study objectives, detailed research methods, and preliminary baseline results of MiHeart.MethodsMiHeart enrolled 2,459 middle-aged male and female participants from the general population of the Greater Miami Area. Enrollment occurred between May 2015 and September 2018 and was restricted to participants aged 40-65 years free of clinical cardiovascular disease (CVD). The baseline examination included assessment of demographics, lifestyles, medical history, and a detailed evaluation of psychosocial characteristics; a comprehensive physical exam; measurement of multiple blood biomarkers including measures of inflammation, advanced lipid testing, and genomics; assessment of subclinical coronary atherosclerotic plaque and vascular function using coronary computed tomography angiography, the coronary artery calcium score, carotid intima-media thickness, pulse wave velocity, and peripheral arterial tonometry; and other tests including 12-lead electrocardiography and assessment of pulmonary function. Blood samples were biobanked to facilitate future ancillary research.ResultsMiHeart enrolled 1,261 men (51.3%) and 1,198 women (48.7%). Mean age was 53 years, 85.6% participants were White and 47.4% were of Hispanic/Latino ethnicity. The study included 7% individuals with diabetes, 33% with hypertension, and 15% used statin therapy at baseline. Overweight or obese participants comprised 72% of the population and 3% were smokers. Median 10-year estimated atherosclerotic CVD risk using the Pooled Cohort Equations was 4%.ConclusionMiHeart will provide important, novel insights into the pathophysiology of early subclini

[ES] En el sector del mueble la necesidad de nuevos diseños es constante. En el siguiente proyecto se expone el desarrollo de un set de mesas auxiliares. El objetivo es ofrecer a los posibles consumidores, una combinación de funcionalidad, versatilidad y diseño. Con este objetivo, se realizará un estudio de mercado, analizando los diferentes estilos y diseños existentes. Con los resultados de este estudio se establecerán las características del nuevo diseño. Se propondrán varias soluciones a través de bocetos que conducirán al diseño definitivo. El diseño irá acompañado de representaciones y renderizados para mostrar el resultado final en diferentes ambientes. Además, se propondrá un método de fabricación y los distintos tipos de materiales a utilizar. Todo el proyecto irá acompañado de planos, despieces, representaciones, estudio de normativa y aquellos documentos requeridos para poder desarrollar el producto. La memoria se cerrará con un presupuesto de fabricación para una tirada definida en el pliego de condiciones., [EN] Many reports foresee a progressive growth in the furniture sector, so the need for new designs is constant in this sector. That is why, in the following project, the development of a set of auxiliary tables for all types of environments is exposed. The aim is to offer potential consumers a combination of functionality, versatility and design at the same time, taking into account the need for space reduction that exists today. With this objective, it has begun with a market study, analysing the different styles and existing designs and thus obtaining conclusions on what customers prevail today. Subsequently, the characteristics and properties that the new design must have been established and a multitude of sketches have been carried out. The final sketches will be made using 3D software and rendered to see the final result in different environments. In addition, the manufacturing method and the different types of materials used for its manufacture will be exposed.

[CA] El objecte d’aquest treball de fi de grau és el disseny d’un conjunt de taula i seients dirigit a optimitzar l’espai. La idea sorgeix a partir de les continues noticies sobre l’encariment del preu del lloguer de la vivenda i el augment de l’edat d’emancipació dels joves. Es buscarà dissenyar un moble auxiliar, destinat a joves, que ocupe poc d’espai quan no s’estiga utilitzant, i que es puga transportar amb relativa facilitat. Per a realitzar aquest producte s’estudiaran els referents tècnics i estètics que puguen aportar al projecte, així com les demandes i requeriments dels usuaris. Aquest últim apartat es realitzarà mitjançant enquestes., [ES] L¿objectiu del projecte es el disseny d¿un conjunt de taula i seients dirigit a optimitzar l¿espai per a habitatges d¿us compartit. El projecte inclourà el disseny conceptual, el disseny de detall, el plec de condicions, pressupost i planimetria El objeto del proyecto es el diseño de un conjunto de mesa y asientos dirigido a optimizar el espacio para viviendas de uso compartido. El proyecto abarcará desde el diseño conceptual, al diseño de detalle, pliego de condiciones, presupuesto y planimetría., [EN] The objective of this final degree project is the design of a set of tables and seats focused on optimizing space. The idea arose from the constant news about the rise of the rental and the increase of the age of emancipation. The main objective of that project will be the design of an ancillary piece of furniture that has the less size possible while it is not using, and that can be easily carried. To design that product, the technical and aesthetics referents are going to be studied. The customers’ requirements and demands are going to be studied too, trough surveys.

[CA] El objecte d’aquest treball de fi de grau és el disseny d’un conjunt de taula i seients dirigit a optimitzar l’espai. La idea sorgeix a partir de les continues noticies sobre l’encariment del preu del lloguer de la vivenda i el augment de l’edat d’emancipació dels joves. Es buscarà dissenyar un moble auxiliar, destinat a joves, que ocupe poc d’espai quan no s’estiga utilitzant, i que es puga transportar amb relativa facilitat. Per a realitzar aquest producte s’estudiaran els referents tècnics i estètics que puguen aportar al projecte, així com les demandes i requeriments dels usuaris. Aquest últim apartat es realitzarà mitjançant enquestes., [ES] L¿objectiu del projecte es el disseny d¿un conjunt de taula i seients dirigit a optimitzar l¿espai per a habitatges d¿us compartit. El projecte inclourà el disseny conceptual, el disseny de detall, el plec de condicions, pressupost i planimetria El objeto del proyecto es el diseño de un conjunto de mesa y asientos dirigido a optimizar el espacio para viviendas de uso compartido. El proyecto abarcará desde el diseño conceptual, al diseño de detalle, pliego de condiciones, presupuesto y planimetría., [EN] The objective of this final degree project is the design of a set of tables and seats focused on optimizing space. The idea arose from the constant news about the rise of the rental and the increase of the age of emancipation. The main objective of that project will be the design of an ancillary piece of furniture that has the less size possible while it is not using, and that can be easily carried. To design that product, the technical and aesthetics referents are going to be studied. The customers’ requirements and demands are going to be studied too, trough surveys.

We investigated historical redlining, a government-sanctioned discriminatory policy, in relation to cardiovascular health (CVH) and whether associations were modified by present-day neighborhood physical and social environments. Data included 4,779 participants (mean age 62 y; SD = 10) from the baseline sample of the Multi-Ethnic Study of Atherosclerosis (MESA; 2000 to 2002). Ideal CVH was a summary measure of ideal levels of seven CVH risk factors based on established criteria (blood pressure, fasting glucose, cholesterol, body mass index, diet, physical activity, and smoking). We assigned MESA participants' neighborhoods to one of four grades (A: best, B: still desirable, C: declining, and D: hazardous) using the 1930s federal Home Owners' Loan Corporation (HOLC) maps, which guided decisions regarding mortgage financing. Two-level hierarchical linear and logistic models, with a random intercept to account for participants nested within neighborhoods (i.e., census tracts) were used to assess associations within racial/ethnic subgroups (non-Hispanic White, non-Hispanic Black, Hispanic, and non-Hispanic Chinese). We found that Black adults who lived in historically redlined areas had a 0.82 (95% CI -1.54, -0.10) lower CVH score compared to those residing in grade A (best) neighborhoods, in a given neighborhood and adjusting for confounders. We also found that as the current neighborhood social environment improved the association between HOLC score and ideal CVH weakened (P < 0.10). There were no associations between HOLC grade and CVH measures or effect modification by current neighborhood conditions for any other racial/ethnic group. Results suggest that historical redlining has an enduring impact on cardiovascular risk among Black adults in the United States.

The analysis here of 83obsidian bifaces (five were not obsidian or too burned/dirty to analyze) indicates an extremely diverse obsidian provenance assemblage with a mix of sources somewhat atypical for Classic contexts in the Middle Salt River Valley&nbsp

There aren’t many pieces of furniture made nationally, that marked the Portuguese interiors in the way Bufete did. These tables as well as cabinet (contador) and chests of wave mouldings (tremidos), camas de bilros and chairs of carved leather, are the most commonly produced in Portugal in the late 17th century, creating a style known as Estilo Nacional.The article aims to study Bufete in depth, by analysing their key-fectures, their origins and their use along thetime. It’s also given attentionto the symbolic valorization that today and in recent past has been attributed to the Bufete, as a symbol of portuguese cultural unity in portuguese state cerimonies, Serão muito poucas as peças de mobiliário de origem e produção nacional que terão marcado de forma tão contínua e distinta os espaços interiores portugueses, como foi o caso do bufete. Estas mesas, juntamente com os contadores e as arcas de tremidos e torcidos, as camas de bilros e as cadeiras de couro lavrado, são os modelos mais característicos do mobiliário produzido em Portugal, nos finais do século XVII, identificando um estilo conhecido como Estilo Nacional.O objectivo desta análise é diferenciar e aprofundar o conhecimento sobre o bufete, através do levantamento das suas características, da sua origem e das várias utilizações que tiveram dentro da casa, em Portugal, desde o inicio da sua produção. É também dadoenfoque à valorização simbólica que, tanto na actualidade como no passado recente, lhe tem vindo a ser atribuída, como elemento unificador e estruturante dos espaços nos momentos protocolares portugueses.

The analysis here of 83obsidian bifaces (five were not obsidian or too burned/dirty to analyze) indicates an extremely diverse obsidian provenance assemblage with a mix of sources somewhat atypical for Classic contexts in the Middle Salt River Valley&nbsp

ObjectiveThe Miami Heart Study (MiHeart) at Baptist Health South Florida is an ongoing, community-based, prospective cohort study aimed at characterizing the prevalence, characteristics, and prognostic value of diverse markers of early subclinical coronary atherosclerosis and of various potential demographic, psychosocial, and metabolic risk factors. We present the study objectives, detailed research methods, and preliminary baseline results of MiHeart.MethodsMiHeart enrolled 2,459 middle-aged male and female participants from the general population of the Greater Miami Area. Enrollment occurred between May 2015 and September 2018 and was restricted to participants aged 40-65 years free of clinical cardiovascular disease (CVD). The baseline examination included assessment of demographics, lifestyles, medical history, and a detailed evaluation of psychosocial characteristics; a comprehensive physical exam; measurement of multiple blood biomarkers including measures of inflammation, advanced lipid testing, and genomics; assessment of subclinical coronary atherosclerotic plaque and vascular function using coronary computed tomography angiography, the coronary artery calcium score, carotid intima-media thickness, pulse wave velocity, and peripheral arterial tonometry; and other tests including 12-lead electrocardiography and assessment of pulmonary function. Blood samples were biobanked to facilitate future ancillary research.ResultsMiHeart enrolled 1,261 men (51.3%) and 1,198 women (48.7%). Mean age was 53 years, 85.6% participants were White and 47.4% were of Hispanic/Latino ethnicity. The study included 7% individuals with diabetes, 33% with hypertension, and 15% used statin therapy at baseline. Overweight or obese participants comprised 72% of the population and 3% were smokers. Median 10-year estimated atherosclerotic CVD risk using the Pooled Cohort Equations was 4%.ConclusionMiHeart will provide important, novel insights into the pathophysiology of early subclini

There aren’t many pieces of furniture made nationally, that marked the Portuguese interiors in the way Bufete did. These tables as well as cabinet (contador) and chests of wave mouldings (tremidos), camas de bilros and chairs of carved leather, are the most commonly produced in Portugal in the late 17th century, creating a style known as Estilo Nacional.The article aims to study Bufete in depth, by analysing their key-fectures, their origins and their use along thetime. It’s also given attentionto the symbolic valorization that today and in recent past has been attributed to the Bufete, as a symbol of portuguese cultural unity in portuguese state cerimonies, Serão muito poucas as peças de mobiliário de origem e produção nacional que terão marcado de forma tão contínua e distinta os espaços interiores portugueses, como foi o caso do bufete. Estas mesas, juntamente com os contadores e as arcas de tremidos e torcidos, as camas de bilros e as cadeiras de couro lavrado, são os modelos mais característicos do mobiliário produzido em Portugal, nos finais do século XVII, identificando um estilo conhecido como Estilo Nacional.O objectivo desta análise é diferenciar e aprofundar o conhecimento sobre o bufete, através do levantamento das suas características, da sua origem e das várias utilizações que tiveram dentro da casa, em Portugal, desde o inicio da sua produção. É também dadoenfoque à valorização simbólica que, tanto na actualidade como no passado recente, lhe tem vindo a ser atribuída, como elemento unificador e estruturante dos espaços nos momentos protocolares portugueses.

We investigated historical redlining, a government-sanctioned discriminatory policy, in relation to cardiovascular health (CVH) and whether associations were modified by present-day neighborhood physical and social environments. Data included 4,779 participants (mean age 62 y; SD = 10) from the baseline sample of the Multi-Ethnic Study of Atherosclerosis (MESA; 2000 to 2002). Ideal CVH was a summary measure of ideal levels of seven CVH risk factors based on established criteria (blood pressure, fasting glucose, cholesterol, body mass index, diet, physical activity, and smoking). We assigned MESA participants' neighborhoods to one of four grades (A: best, B: still desirable, C: declining, and D: hazardous) using the 1930s federal Home Owners' Loan Corporation (HOLC) maps, which guided decisions regarding mortgage financing. Two-level hierarchical linear and logistic models, with a random intercept to account for participants nested within neighborhoods (i.e., census tracts) were used to assess associations within racial/ethnic subgroups (non-Hispanic White, non-Hispanic Black, Hispanic, and non-Hispanic Chinese). We found that Black adults who lived in historically redlined areas had a 0.82 (95% CI -1.54, -0.10) lower CVH score compared to those residing in grade A (best) neighborhoods, in a given neighborhood and adjusting for confounders. We also found that as the current neighborhood social environment improved the association between HOLC score and ideal CVH weakened (P < 0.10). There were no associations between HOLC grade and CVH measures or effect modification by current neighborhood conditions for any other racial/ethnic group. Results suggest that historical redlining has an enduring impact on cardiovascular risk among Black adults in the United States.

There aren’t many pieces of furniture made nationally, that marked the Portuguese interiors in the way Bufete did. These tables as well as cabinet (contador) and chests of wave mouldings (tremidos), camas de bilros and chairs of carved leather, are the most commonly produced in Portugal in the late 17th century, creating a style known as Estilo Nacional.The article aims to study Bufete in depth, by analysing their key-fectures, their origins and their use along thetime. It’s also given attentionto the symbolic valorization that today and in recent past has been attributed to the Bufete, as a symbol of portuguese cultural unity in portuguese state cerimonies, Serão muito poucas as peças de mobiliário de origem e produção nacional que terão marcado de forma tão contínua e distinta os espaços interiores portugueses, como foi o caso do bufete. Estas mesas, juntamente com os contadores e as arcas de tremidos e torcidos, as camas de bilros e as cadeiras de couro lavrado, são os modelos mais característicos do mobiliário produzido em Portugal, nos finais do século XVII, identificando um estilo conhecido como Estilo Nacional.O objectivo desta análise é diferenciar e aprofundar o conhecimento sobre o bufete, através do levantamento das suas características, da sua origem e das várias utilizações que tiveram dentro da casa, em Portugal, desde o inicio da sua produção. É também dadoenfoque à valorização simbólica que, tanto na actualidade como no passado recente, lhe tem vindo a ser atribuída, como elemento unificador e estruturante dos espaços nos momentos protocolares portugueses.

Magneto-electric antiferromagnets hold promise for future spintronic devices, as they offer magnetic field hardness, high switching speeds combined with electric and magnetic control of their order parameters, owing to the magneto-electric coupling [1]. As information and functionality is encoded in the antiferromagnetic order parameter, its manipulation, read-out and nanoscale texture are paramount for device operation, as well as interesting from a fundamental point of view. E.g. spin-textures in such materials are theorized to carry an intrinsic magnetization [2]. Here we study a single crystal ‘textbook’ magneto-electric antiferromagnet, Cr2O3, by nanoscale imaging of its surface magnetization via magnetic stray field imaging by scanning nitrogen vacancy magnetometry [3]. This surface magnetization is directly linked to the bulk Neel vector of Cr2O3 and thereby allows for nanoscale imaging of antiferromagnet spin textures. After confirming magneto-electric poling [4], local electrodes are utilized to nucleate single domain walls, which we then study on the nanometer scale. Manipulation of the domain wall is demonstrated both by local laser heating [5], as well as the creation of an energy landscape for the domain wall via topographic structuring [3]. We analyze the interaction of the domain wall with topographic islands both experimentally and in simulations. This analysis yields information about the domain wall boundary conditions at topographic edges and an estimate of the full 3D-profile of the texture based on minimizing the domain walls surface energy. A Snell like refraction of the domain wall path is found, that can be represented in an analytical approximation as a ‘refractive index’ for a given island dimension as demonstrated for a range of incidence angles. We then observe bistable domain wall paths configurations and switching between them is demonstrated and imaged experimentally. This pinning and control of the domain wall position constitutes the

Magneto-electric antiferromagnets hold promise for future spintronic devices, as they offer magnetic field hardness, high switching speeds combined with electric and magnetic control of their order parameters, owing to the magneto-electric coupling [1]. As information and functionality is encoded in the antiferromagnetic order parameter, its manipulation, read-out and nanoscale texture are paramount for device operation, as well as interesting from a fundamental point of view. E.g. spin-textures in such materials are theorized to carry an intrinsic magnetization [2]. Here we study a single crystal ‘textbook’ magneto-electric antiferromagnet, Cr2O3, by nanoscale imaging of its surface magnetization via magnetic stray field imaging by scanning nitrogen vacancy magnetometry [3]. This surface magnetization is directly linked to the bulk Neel vector of Cr2O3 and thereby allows for nanoscale imaging of antiferromagnet spin textures. After confirming magneto-electric poling [4], local electrodes are utilized to nucleate single domain walls, which we then study on the nanometer scale. Manipulation of the domain wall is demonstrated both by local laser heating [5], as well as the creation of an energy landscape for the domain wall via topographic structuring [3]. We analyze the interaction of the domain wall with topographic islands both experimentally and in simulations. This analysis yields information about the domain wall boundary conditions at topographic edges and an estimate of the full 3D-profile of the texture based on minimizing the domain walls surface energy. A Snell like refraction of the domain wall path is found, that can be represented in an analytical approximation as a ‘refractive index’ for a given island dimension as demonstrated for a range of incidence angles. We then observe bistable domain wall paths configurations and switching between them is demonstrated and imaged experimentally. This pinning and control of the domain wall position constitutes the

[ES] Se realiza un rediseño de una mesa ampliable mediante un sistema de rotación, para pasar de 4 a 8 personas y transformarla en una mesa adaptada especialmente para juegos de rol con múltiples accesorios para cada jugador. Pensado para poder utilizar la mesa tanto en su uso cotidiano de comedor o de principal de la casa, como para disponer de ella para juegos de rol por sus dimensiones. Se aplican modificaciones en el diseño de una mesa ampliable añadiendo accesorios que complementen las actividades alternativas de juego y que de otra manera son incómodas de realizar para el usuario mientras realiza estas acciones., [EN] The redesign of an expandable table is made by a rotation system. It¿s ment to go from 4 to 8 people and transform into a table specially thought for role-gaming with multiple accesories for each player. Designed to be used both in your daily use of dinning room or main house, as well as to have it for role-playing games for the dimensions used. Modifications are applied to the design of an expandable table by adding accessories that complement alternative gaming activities and that are otherwise uncomfortable for the user to perform while performing these actions.

[ES] Con el presente Trabajo Fin de Grado (TFG) se presenta el diseño de una mesa modular de tren, concretamente de larga distancia, con el objetivo de mejorar el nivel de confort del pasajero durante su uso y del mismo modo ofrecer una opción más ecológica. En cuanto al diseño que se ha llevara a cabo se quiere dar un aspecto innovador, de comodidad y ligereza. Por otro lado, el diseño deberá cumplir con las normativas establecidas aprobadas por la UNE adaptándose de ese modo las dimensiones del producto al usuario adoptando recomendaciones de economía estandarizadas. Para ello se realizaran los estudios de mercado correspondiente a la vez que diferentes encuestas a usuarios de dicho transporte para solucionar de este modo todos los problemas de comodidad y accesibilidad posible. En conclusión, el objetivo principal de este proyecto es mejorar tanto los materiales como la comodidad y la funcionalidad de las mesas de los medios de transporte concretamente de los trenes de alta velocidad., [EN] With the present End of Degree Work (TFG), the design of a modular train table, specifically for long distance, with the objective of improving the passenger comfort level during its use and at the same time offering a more ecological option. As for the design that has been carried out, we want to give an innovative aspect, of comfort and lightness. On the other hand, the design must comply with the established regulations approved by the UNE, thus adapting the dimensions of the product to the user by adopting standardized ergonomic recommendations. To this end, the corresponding market studies will be carried out at the same time as different surveys of users of said transport in order to solve all the problems of comfort and accessibility possible. In conclusion, the main objective of this project is to improve both the materials and the comfort and functionality of the tables of the means of transport, specifically high-speed trains

[ES] Se realiza un rediseño de una mesa ampliable mediante un sistema de rotación, para pasar de 4 a 8 personas y transformarla en una mesa adaptada especialmente para juegos de rol con múltiples accesorios para cada jugador. Pensado para poder utilizar la mesa tanto en su uso cotidiano de comedor o de principal de la casa, como para disponer de ella para juegos de rol por sus dimensiones. Se aplican modificaciones en el diseño de una mesa ampliable añadiendo accesorios que complementen las actividades alternativas de juego y que de otra manera son incómodas de realizar para el usuario mientras realiza estas acciones., [EN] The redesign of an expandable table is made by a rotation system. It¿s ment to go from 4 to 8 people and transform into a table specially thought for role-gaming with multiple accesories for each player. Designed to be used both in your daily use of dinning room or main house, as well as to have it for role-playing games for the dimensions used. Modifications are applied to the design of an expandable table by adding accessories that complement alternative gaming activities and that are otherwise uncomfortable for the user to perform while performing these actions.

[ES] Se realiza un rediseño de una mesa ampliable mediante un sistema de rotación, para pasar de 4 a 8 personas y transformarla en una mesa adaptada especialmente para juegos de rol con múltiples accesorios para cada jugador. Pensado para poder utilizar la mesa tanto en su uso cotidiano de comedor o de principal de la casa, como para disponer de ella para juegos de rol por sus dimensiones. Se aplican modificaciones en el diseño de una mesa ampliable añadiendo accesorios que complementen las actividades alternativas de juego y que de otra manera son incómodas de realizar para el usuario mientras realiza estas acciones., [EN] The redesign of an expandable table is made by a rotation system. It¿s ment to go from 4 to 8 people and transform into a table specially thought for role-gaming with multiple accesories for each player. Designed to be used both in your daily use of dinning room or main house, as well as to have it for role-playing games for the dimensions used. Modifications are applied to the design of an expandable table by adding accessories that complement alternative gaming activities and that are otherwise uncomfortable for the user to perform while performing these actions.

[ES] Con el presente Trabajo Fin de Grado (TFG) se presenta el diseño de una mesa modular de tren, concretamente de larga distancia, con el objetivo de mejorar el nivel de confort del pasajero durante su uso y del mismo modo ofrecer una opción más ecológica. En cuanto al diseño que se ha llevara a cabo se quiere dar un aspecto innovador, de comodidad y ligereza. Por otro lado, el diseño deberá cumplir con las normativas establecidas aprobadas por la UNE adaptándose de ese modo las dimensiones del producto al usuario adoptando recomendaciones de economía estandarizadas. Para ello se realizaran los estudios de mercado correspondiente a la vez que diferentes encuestas a usuarios de dicho transporte para solucionar de este modo todos los problemas de comodidad y accesibilidad posible. En conclusión, el objetivo principal de este proyecto es mejorar tanto los materiales como la comodidad y la funcionalidad de las mesas de los medios de transporte concretamente de los trenes de alta velocidad., [EN] With the present End of Degree Work (TFG), the design of a modular train table, specifically for long distance, with the objective of improving the passenger comfort level during its use and at the same time offering a more ecological option. As for the design that has been carried out, we want to give an innovative aspect, of comfort and lightness. On the other hand, the design must comply with the established regulations approved by the UNE, thus adapting the dimensions of the product to the user by adopting standardized ergonomic recommendations. To this end, the corresponding market studies will be carried out at the same time as different surveys of users of said transport in order to solve all the problems of comfort and accessibility possible. In conclusion, the main objective of this project is to improve both the materials and the comfort and functionality of the tables of the means of transport, specifically high-speed trains

[ES] Con el presente Trabajo Fin de Grado (TFG) se presenta el diseño de una mesa modular de tren, concretamente de larga distancia, con el objetivo de mejorar el nivel de confort del pasajero durante su uso y del mismo modo ofrecer una opción más ecológica. En cuanto al diseño que se ha llevara a cabo se quiere dar un aspecto innovador, de comodidad y ligereza. Por otro lado, el diseño deberá cumplir con las normativas establecidas aprobadas por la UNE adaptándose de ese modo las dimensiones del producto al usuario adoptando recomendaciones de economía estandarizadas. Para ello se realizaran los estudios de mercado correspondiente a la vez que diferentes encuestas a usuarios de dicho transporte para solucionar de este modo todos los problemas de comodidad y accesibilidad posible. En conclusión, el objetivo principal de este proyecto es mejorar tanto los materiales como la comodidad y la funcionalidad de las mesas de los medios de transporte concretamente de los trenes de alta velocidad., [EN] With the present End of Degree Work (TFG), the design of a modular train table, specifically for long distance, with the objective of improving the passenger comfort level during its use and at the same time offering a more ecological option. As for the design that has been carried out, we want to give an innovative aspect, of comfort and lightness. On the other hand, the design must comply with the established regulations approved by the UNE, thus adapting the dimensions of the product to the user by adopting standardized ergonomic recommendations. To this end, the corresponding market studies will be carried out at the same time as different surveys of users of said transport in order to solve all the problems of comfort and accessibility possible. In conclusion, the main objective of this project is to improve both the materials and the comfort and functionality of the tables of the means of transport, specifically high-speed trains

The optimization of mesa etch for a quasi-vertical gallium nitride (GaN) Schottky barrier diode (SBD) by inductively coupled plasma (ICP) etching was comprehensively investigated in this work, including selection of the etching mask, ICP power, radio frequency (RF) power, ratio of mixed gas, flow rate, and chamber pressure, etc. In particular, the microtrench at the bottom corner of the mesa sidewall was eliminated by a combination of ICP dry etching and tetramethylammonium hydroxide (TMAH) wet treatment. Finally, a highly anisotropic profile of the mesa sidewall was realized by using the optimized etch recipe, and a quasi-vertical GaN SBD was demonstrated, achieving a low reverse current density of 10−8 A/cm2 at −10 V., Electronic Components, Technology and Materials

The optimization of mesa etch for a quasi-vertical gallium nitride (GaN) Schottky barrier diode (SBD) by inductively coupled plasma (ICP) etching was comprehensively investigated in this work, including selection of the etching mask, ICP power, radio frequency (RF) power, ratio of mixed gas, flow rate, and chamber pressure, etc. In particular, the microtrench at the bottom corner of the mesa sidewall was eliminated by a combination of ICP dry etching and tetramethylammonium hydroxide (TMAH) wet treatment. Finally, a highly anisotropic profile of the mesa sidewall was realized by using the optimized etch recipe, and a quasi-vertical GaN SBD was demonstrated, achieving a low reverse current density of 10−8 A/cm2 at −10 V., Electronic Components, Technology and Materials

[ES] En el presente documento se expone la realización del diseño de una silla convertible en mesa a partir de un mecanismo articulado. Para la ejecución de este proyecto se han llevado a cabo los estudios de mercado, ergonomía, resistencia estructural, estabilidad, selección de materiales, etc. A fin de garantizar la calidad y funcionalidad de dicho mueble, cumpliendo en todo momento con las normativas vigentes. Se han analizado cada una de las piezas que conforman el diseño y el mecanismo que contiene, de forma exhaustiva para su fabricación industrial, detallando el tipo de maquinaria, herramienta o útil utilizado en cada operación. Además, se ha diseñado una bisagra especial para el plegado requerido y se ha construido un prototipo para estudiar su comportamiento. Para finalizar, se ha realizado un presupuesto de los costes de fabricación y venta al público del producto., [EN] In this document the design of a chair that can be converted into a table using an articulated mechanism is presented . To perform this project it has been carried out the market survey, ergonomics, structural resistance, stability, material selections, etc. According to the applicable legislation to ensure the quality and functionality of the furniture. Furthermore, each piece of the project design and the mechanism involved has been exhaustively analyzed (busca como se escribe) for industrial manufacturing, detailing the type of machinery and tool use in every step. In addition, a special hinge has been designed for the required folding and a prototype has been built to study its behavior. Finally, a budget has been made for the costs of manufacturing and selling the product to the public.

[ES] El proyecto corresponde al trabajo EPS realizado como Erasmus+ en Bucarest. Para este proyecto se trabaja en conjunto con el Instituto Nacional de Desarrollo de Investigaciones para Textiles y Cuero de Bucarest (Institutul National De Cercetare-Dezvoltare Pentru Textile Si Pielarie). El objetivo del proyecto es el diseño de un mueble multifuncional, que además tenga un acabado a prueba de fuego y de agua y que, también sea eco-sostenible. Los materiales principales del producto son madera de nogal y piel con curtido vegetal. Se propone el diseño de una mesa, cuya función principal sea la de mesa auxiliar, pero que además se pueda convertir en escritorio cuando sea necesario. Esto se consigue con la ayuda de un mecanismo incorporado que permite elevar la parte superior de la mesa quedando, de este modo, a la altura necesaria para poder utilizarla como una mesa de acción. Esta parte superior incluye otro mecanismo rotatorio, el cual permite al usuario elegir entre dos superficies distintas de la mesa: una con un acabado de piel (aporta una mayor comodidad cuando se utiliza como escritorio) y otra, con un acabado de madera (ofrece una mayor estabilidad). La mesa, además, también posee espacio de almacenamiento, para poder guardar cinco taburetes que, encajados entre sí, forman un cubo, que se puede utilizar como un único asiento., [EN] The project corresponds to the EPS project done during the Erasmus + intership in Bucharest. For this project, we worked with the National Institute for Textile and Leather Research Development of Bucharest (Institutul National De Cercetare-Dezvoltare Pentru Textile Si Pielarie). The objective of the project is the design of a multifunctional piece of furniture, which also has a fire and water proof finish and also, is eco-sustainable. The main materials of the product are walnut wood and leather with vegetable tanning. It is proposed the design of a table, whose main function is as an auxiiar table, but it can be converted into a desk when it is necessary.. This is achieved with the help of a built-in mechanism that allows the upper part of the table to be raised, thus being at the necessary height to be used as an action table. This upper part includes another rotary mechanism, which allows the user to choose between two different surfaces of the table: one with a leather finish (provides more comfort when it is used as a desk) and another one, with a wood finish (offers a better stability). In addition, the table also has storage space, to store five stools that, embedded together, form a cube, which can be used as a single seat.

[ES] El proyecto corresponde al trabajo EPS realizado como Erasmus+ en Bucarest. Para este proyecto se trabaja en conjunto con el Instituto Nacional de Desarrollo de Investigaciones para Textiles y Cuero de Bucarest (Institutul National De Cercetare-Dezvoltare Pentru Textile Si Pielarie). El objetivo del proyecto es el diseño de un mueble multifuncional, que además tenga un acabado a prueba de fuego y de agua y que, también sea eco-sostenible. Los materiales principales del producto son madera de nogal y piel con curtido vegetal. Se propone el diseño de una mesa, cuya función principal sea la de mesa auxiliar, pero que además se pueda convertir en escritorio cuando sea necesario. Esto se consigue con la ayuda de un mecanismo incorporado que permite elevar la parte superior de la mesa quedando, de este modo, a la altura necesaria para poder utilizarla como una mesa de acción. Esta parte superior incluye otro mecanismo rotatorio, el cual permite al usuario elegir entre dos superficies distintas de la mesa: una con un acabado de piel (aporta una mayor comodidad cuando se utiliza como escritorio) y otra, con un acabado de madera (ofrece una mayor estabilidad). La mesa, además, también posee espacio de almacenamiento, para poder guardar cinco taburetes que, encajados entre sí, forman un cubo, que se puede utilizar como un único asiento., [EN] The project corresponds to the EPS project done during the Erasmus + intership in Bucharest. For this project, we worked with the National Institute for Textile and Leather Research Development of Bucharest (Institutul National De Cercetare-Dezvoltare Pentru Textile Si Pielarie). The objective of the project is the design of a multifunctional piece of furniture, which also has a fire and water proof finish and also, is eco-sustainable. The main materials of the product are walnut wood and leather with vegetable tanning. It is proposed the design of a table, whose main function is as an auxiiar table, but it can be converted into a desk when it is necessary.. This is achieved with the help of a built-in mechanism that allows the upper part of the table to be raised, thus being at the necessary height to be used as an action table. This upper part includes another rotary mechanism, which allows the user to choose between two different surfaces of the table: one with a leather finish (provides more comfort when it is used as a desk) and another one, with a wood finish (offers a better stability). In addition, the table also has storage space, to store five stools that, embedded together, form a cube, which can be used as a single seat.

[ES] Estudio cuyo objetivo principal es la elaboración de un mueble multifuncional transformable con la capacidad de ser silla y mesa según el uso que se le requiera en cada ocasión. Se designarán las condiciones viables técnicas en el ámbito estructural en el que se analizan todos los elementos que componen el producto para definir las dimensiones f inales del diseño propuesto y describir su segura realización., [EN] Study which objective is the elaboration of a multifunctional piece of furniture with the capacity to be chair or table according to the use that its required for each occasion. Will designate technic feasible conditions in the structural area in which all the elements that make up the product are analyzed to define the final dimensions of the proposed design and describe its safe completion.