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Khalid Aziz Ansari,1 Marwan Jabr Alwazzeh,2 Feras Ahmed Alkuwaiti,2 Faraz Ahmed Farooqi,3 Noor Al Khathlan,1 Hussain Almutawah,1 Mustafa Alahmed,1 Hussain Alfaraj,1 Ahmed Aljarrash,1 Jaffar Almadhary,1 Sarah Alwarthan,2 Ahmed Mohammed Alsahlawi,2 Abdullah Bandar Almashouf,2 Moammer Alqasim,2 Elaf Alkuwaiti4 1Department of Respiratory Care, College of Applied Medical Science, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Department of Internal Medicine, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 3Department of Dental Education, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 4College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaCorrespondence: Khalid Aziz Ansari, Email kaansari@iau.edu.saPurpose: This study investigated the clinical determinants of mortality in hospitalized patients infected with COVID-19.Patients and Methods: A retrospective multicenter large cohort of COVID-19 patients hospitalized between March 2020 and February 2021. We included patients admitted with a confirmed COVID-19 infection with positive COVID-19 through real-time polymerase chain reaction (RT-PCR). SPSS version 25.0 (Armonk, NY: IBM Corp.) was used to analyze the data.Results: Among the study participants (n = 1444), the mean age of the population was 49.22± 17.69 years, of which 63.9% were males (n = 924). Overall, the mean age for non-survivors was 55.65 ± 16.41 years and the length of ICU stay was 13.95 ± 12.4 years. The most common comorbidity among the study subjects was hypertension (HTN) (32.7%), followed by cardiovascular disease (CVD) (10.7%). Patients who were mechanically ventilated (MV) had higher mortality than those who did not require MV (p < 0.001).Conclusion: Our study concluded that old age, the presence of underlying cardiovascular conditions, an abnormal WBC count (leukopenia or leukocytosis), and abnorma

Background: There is a need for safe disinfection methods without a detrimental effect on the acrylic denture base. Aim: the purpose of the current study was to evaluate the effect of ozonated water and two protocols of microwave disinfection on tensile bond strength of high-impact acrylic. Material and methods: Eighty samples were divided into four major groups: one control and three experimental groups, 20 specimens each. The experimental groups each received either disinfection by ozonated water, microwave 850W/1min, or microwave 650W/6min. Further division of the major groups into two sub-groups depending on the number of disinfection cycles and total immersion time in distilled water: One cycle and one day versus seven cycles and seven days. The control group specimens were immersed in distilled water without any disinfection for either one day or seven days. Tensile strength testing was performed on the specimens from the eight groups. The data were analyzed by SPSS version 21#. The ANOVA and Tukey-HSD multiple comparison tests were used for comparison for groups. Results: A non-significant difference in the tensile strength was observed in the groups subjected to one cycle of ozone or microwave disinfection at 850W/1min. There was a significant decrease in tensile strength for the specimens subjected to one cycle of 650W/6min microwaving. The number of testing cycles and storage time in distilled water had a significant impact on the tensile strength of the acrylic in all tested groups, by decreasing it. Conclusion: Ozone disinfection and microwaving at 850W for one minute did not affect the tensile strength of the acrylic, but repeated disinfection over seven days at one cycle per day impaired the tensile strength of the acrylic resin., Antecedentes: Existe la necesidad de métodos de desinfección seguros sin un efecto perjudicial sobre la base de prótesis acrílica. Objetivo: el objetivo del presente estudio fue evaluar el efecto del agua ozonizada y dos protocolos de desinfección por microondas sobre la resistencia a la tracción del acrílico de alto impacto. Material y Métodos: Ochenta muestras se dividieron en cuatro grandes grupos: un grupo control y tres grupos experimentales, 20 especímenes cada uno. Cada grupo experimental recibió desinfección con agua ozonizada, microondas de 850 W/1 min o microondas de 650 W/6 min. Los grupos principales se dividieron en dos subgrupos según el número de ciclos de desinfección y el tiempo total de inmersión en agua destilada: un ciclo y un día versus siete ciclos y siete días. Las muestras del grupo de control se sumergieron en agua destilada sin ninguna desinfección durante uno o siete días, respectivamente. Se realizaron pruebas de resistencia a la tracción en las muestras de los ocho grupos. Los datos fueron analizados por SPSS versión 21. Se utilizaron las pruebas de comparación múltiple ANOVA y Tukey-HSD para la comparación entre grupos.. Resultados: Se observó una diferencia no significativa en la resistencia a la tracción en los grupos sometidos a un ciclo de desinfección con ozono o microondas a 850 W/1 min. Hubo una disminución significativa en la resistencia a la tracción para las muestras sometidas a un ciclo de microondas de 650 W/6 min. El número de ciclos de prueba junto al tiempo de almacenamiento en agua destilada tuvieron un impacto significativo en la resistencia a la tracción del acrílico en todos los grupos probados, al disminuirla. Conclusión: La desinfección con ozono y el microondas a 850 W durante un minuto no afectaron la resistencia a la tracción del acrílico, pero la desinfección repetida durante siete días en un ciclo por día afectó la resistencia a la tracción de la resina acrílica.