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BackgroundObesity is a significant contributor to breast cancer recurrence and mortality. A central mechanism by which obesity stimulates cancer progression is through chronic, low-grade inflammation in adipose tissue. Exercise interventions to target chronic inflammation has a potential to improve obesity- and breast cancer-related outcomes; however, no studies have investigated the roles of exercise in modulating adipose tissue inflammation in breast cancer survivors. Also, it is unclear which exercise prescription would be optimal to maximize the outcomes. Therefore, we designed a randomized controlled trial (Taking AIM at Breast Cancer: Targeting Adiposity and Inflammation with Movement to Improve Prognosis in Breast Cancer Survivors [AIM] Trial) to examine the mechanisms by which different modalities of exercise impact chronic inflammation as a biomarker of breast cancer prognosis.MethodsThe AIM trial is a prospective, three-armed, phase II randomized controlled trial investigating the effects of a 16-week supervised circuit aerobic and resistance exercise (CARE) program versus a traditional aerobic and resistance exercise (TARE) program and attention control (AC) on adipose tissue inflammation in breast cancer survivors. 276 patients who are diagnosed with stage 0-III breast cancer, post-treatment, sedentary, and centrally obese are randomized to one of the three groups. The CARE and TARE groups participate in thrice-weekly supervised exercise sessions for 16 weeks. The AC group are offered the CARE program after the intervention period. The primary endpoint is adipose tissue inflammation assessed by core biopsy and blood draw. The secondary and tertiary endpoints are sarcopenic obesity, physical fitness and function, and patient reported outcomes. The exploratory outcomes are long-term breast cancer outcomes.DiscussionThis is the first randomized controlled trial examining the effects of exercise on adipose tissue inflammation in obese, breast cancer survivor

We study the kinetic mixing between the cosmic microwave background (CMB) photon and the birefringent dark photon as a source of cosmic birefringence. We show that indeed the birefringence of the dark photon propagates to the CMB photon, but the resulting birefringence may not be uniform over the sky. Moreover, our investigation sheds light on the essential role played by kinetic mixing in the generation of two fundamental characteristics of the CMB: circular polarization and spectral distortion., Comment: 6 pages, 1 figure

We study the kinetic mixing between the cosmic microwave background (CMB) photon and the birefringent dark photon as a source of cosmic birefringence. We show that indeed the birefringence of the dark photon propagates to the CMB photon, but the resulting birefringence may not be uniform over the sky. Moreover, our investigation sheds light on the essential role played by kinetic mixing in the generation of two fundamental characteristics of the CMB: circular polarization and spectral distortion., Comment: 6 pages, 1 figure

It is clear that matter is dominant in the Universe compared to antimatter. We call this problem baryon asymmetry. The baryon asymmetry is experimentally determined by both cosmic microwave background and big bang nucleosynthesis measurements. To resolve the baryon number asymmetry of the Universe as well as neutrino oscillations, we study a radiative seesaw model in a modular $A_4$ symmetry. Degenerate heavy Majorana neutrino masses can be naturally realized in an appropriate assignments under modular $A_4$ with large imaginary part of modulus $\tau$, and it can induce measured baryon number via resonant leptogenesis that is valid in around TeV scale energy theory. We also find that the dominant contribution to the CP asymmetry arises from Re[$\tau$] through our numerical analysis satisfying the neutrino oscillation data., Comment: 20 pages, 2 tables, 6 figures

We present DeeLeMa, a deep learning network to analyze energies and momenta in particle collisions at high energy colliders, especially DeeLeMa is constructed based on symmetric event topology, and the generated mass distributions show robust peaks at the physical masses after the combinatoric uncertainties, and detector smearing effects are taken into account. DeeLeMa can be widely used in different event topologies by adopting the corresponding kinematic symmetries.

We explore muon anomalous magnetic moment (muon $g-2$) in a scotogenic neutrino model with a gauged lepton number symmetry $U(1)_{\mu-\tau}$. In this model, a dominant muon $g-2$ contribution comes not from an additional gauge sector but from a Yukawa sector. In our numerical $\Delta \chi^2$ analysis, we show that our model is in favor of normal hierarchy with some features. We demonstrate one benchmark point, satisfying muon $g-2$ at the best fit value $25.1\times10^{-10}$., Comment: 12 pages, 3 tables, 1 figure; version accepted for publication in Physics Letters B

The inelastic dark matter model is one kind of popular models for the light dark matter (DM) below $O(1)$ GeV. If the mass splitting between DM excited and ground states is small enough, the co-annihilation becomes the dominant channel for thermal relic density and the DM excited state can be long-lived at the collider scale. We study scalar and fermion inelastic dark matter models for $ {\cal O}(1) $ GeV DM at Belle II with $ U(1)_D $ dark gauge symmetry broken into its $Z_2$ subgroup. We focus on dilepton displaced vertex signatures from decays of the DM excited state. With the help of precise displaced vertex detection ability at Belle II, we can explore the DM spin, mass and mass splitting between DM excited and ground states. Especially, we show scalar and fermion DM candidates can be discriminated and the mass and mass splitting of DM sector can be determined within the percentage of deviation for some benchmark points. Furthermore, the allowed parameter space to explain the excess of muon $(g-2)_\mu$ is also studied and it can be covered in our displaced vertex analysis during the early stage of Belle II experiment., Comment: 42 pages, 13 figures, and 5 tables, version published in JHEP

The inelastic dark matter model is one kind of popular models for the light dark matter (DM) below $O(1)$ GeV. If the mass splitting between DM excited and ground states is small enough, the co-annihilation becomes the dominant channel for thermal relic density and the DM excited state can be long-lived at the collider scale. We study scalar and fermion inelastic dark matter models for $ {\cal O}(1) $ GeV DM at Belle II with $ U(1)_D $ dark gauge symmetry broken into its $Z_2$ subgroup. We focus on dilepton displaced vertex signatures from decays of the DM excited state. With the help of precise displaced vertex detection ability at Belle II, we can explore the DM spin, mass and mass splitting between DM excited and ground states. Especially, we show scalar and fermion DM candidates can be discriminated and the mass and mass splitting of DM sector can be determined within the percentage of deviation for some benchmark points. Furthermore, the allowed parameter space to explain the excess of muon $(g-2)_\mu$ is also studied and it can be covered in our displaced vertex analysis during the early stage of Belle II experiment., Comment: 42 pages, 13 figures, and 5 tables, version published in JHEP

We construct a successful model to explain the muon anomalous magnetic moment originated from Yukawa terms. Thanks to a modular $A_4$ flavor symmetry, there are not any lepton flavor violations from the terms that would spoil the model. We also investigate a predictive radiative seesaw model including dark matter candidate at favorable fixed points of $\tau=\omega,\ i$ obtained by recent analysis of the stabilized moduli values from the possible configurations of the flux compactifications. In the result, we show our predictions on the Dirac CP and Majorana phases, the neutrino masses through $\chi^2$ analysis. Then, we demonstrate the allowed regions to satisfy the muon anomalous magnetic moment and the observed relic density of dark matter in terms of valid mass eigenstates., Comment: 28 pages, 14 figures, we updated new figures and added some discussions on neutrino mass explanations

We re-examine current and future constraints on a heavy dilaton coupled to a simple dark sector consisting of a Majorana fermion or a St\"uckelberg vector field. We include three different treatments of dilaton-Higgs mixing, paying particular attention to a gauge-invariant formulation of the model. Moreover, we also invite readers to re-examine effective field theories of vector dark matter, which we show are missing important terms. Along with the latest Higgs coupling data, heavy scalar search results, and dark matter density/direct detection constraints, we study the LHC bounds on the model and estimate the prospects of dark matter production at the future HL-LHC and 100 TeV FCC colliders. We additionally compute novel perturbative unitarity constraints involving vector dark matter, dilaton and gluon scattering., Comment: 18 pages, 10 figures

A long standing problem in kinematics at the hadron colliders is to determine the mass of invisible particles. This issue is particularly important for the signals of dark matter, which becomes one of the prominent targets of future collider experiments. In this paper, we show that the additional information from the precise timing measurement, which will be available at the planned high-liminosity run of the LHC (HL-LHC), will shade new light on the kinematics study. As a concrete example, we focus on the signal of the pair produced long-lived particles ($LLP_{1,2}$), respectively leaving displaced vertex with visible ($V_{1,2}$) and invisible ($I_{1,2}$) final state, $pp \to LLP_1+LLP_2 \to (V_1+I_1)+(V_2+I_2)$. We explicitly show that this system is completely solvable with timing information., Comment: 14 pages, 5 figures

We present the activities performed during the first MadAnalysis 5 workshop on LHC recasting that has been organized at High 1 (Gangwon privince, Korea) on August 20-27, 2017. This report includes details on the implementation in the MadAnalysis 5 framework of eight ATLAS and CMS analyses, as well as a description of the corresponding validation and the various issues that have been observed., Comment: 57 pages, 13 figures. Proceedings of the first MadAnalysis 5 workshop on LHC recasting (https://indico.cern.ch/event/637941)

We present the activities performed during the first MadAnalysis 5 workshop on LHC recasting that has been organized at High 1 (Gangwon privince, Korea) on August 20-27, 2017. This report includes details on the implementation in the MadAnalysis 5 framework of eight ATLAS and CMS analyses, as well as a description of the corresponding validation and the various issues that have been observed., Comment: 57 pages, 13 figures. Proceedings of the first MadAnalysis 5 workshop on LHC recasting (https://indico.cern.ch/event/637941)

Dong Woo Kang,1 Hyun Kook Lim,2 Soo-hyun Joo,1 Na Rae Lee,1 Chang Uk Lee1 1Department of Psychiatry, Seoul St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, 2Department of Psychiatry, Yeoui-do St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea Objective: Previous research has indicated that there are potential associations between education and total hippocampal volume in the trajectory of Alzheimer’s disease (AD). However, the correlation between education and hippocampal subfield volumes in the progression of AD has yet to be understood. This study examined the relationship between education, which is a standard proxy for cognitive reserve, and hippocampal subfield volumes in healthy and amnestic mild cognitive impairment (aMCI) groups.Subjects and methods: Thirty-eight subjects with aMCI and 39 healthy control subjects underwent 3 T magnetic resonance imaging, and hippocampal subfield volumes were measured by automated segmentation. Multiple linear regression analysis was used to determine the association between education and hippocampal subfield volumes.Results: Education had a significant negative correlation with the left parasubiculum, presubiculum, and subiculum volumes in the aMCI group. In addition, multiple subfield volumes including left parasubiculum, left/right presubiculum, left cornus ammonis (CA)3, and left CA4 showed a significant correlation with the neuropsychological test scores in the control group and aMCI group.Conclusion: These findings contribute to a better understanding of the association between education, hippocampal subfield volumes, and amnestic cognitive functions in the early phase of AD. Keywords: education, hippocampus, presubiculum, subiculum, mild cognitive impairment, cognitive reserve

In models with universal extra dimensions (UED), the lightest Kaluza-Klein excitation of neutral electroweak gauge bosons is a stable, weakly interacting massive particle and thus is a candidate for dark matter thanks to Kaluza-Klein parity. We examine concrete model realizations of such dark matter in the context of non-minimal UED extensions. The boundary localized kinetic terms for the electroweak gauge bosons lead to a non-trivial mixing among the first Kaluza-Klein excitations of the ${\rm SU}(2)_W$ and ${\rm U}(1)_Y$ gauge bosons and the resultant low energy phenomenology is rich. We investigate implications of various experiments including low energy electroweak precision measurements, direct and indirect detection of dark matter particles and direct collider searches at the LHC. Notably, we show that the electroweak Kaluza-Klein dark matter can be as heavy as 2.4 TeV, which is significantly higher than $1.3$ TeV as is indicated as an upper bound in the minimal UED model., Comment: 29 pages, 10 figures, 1 table; v2: Fig 10 added, remarks on the potential influence of Sommerfeld enhancement added, typos corrected, references added, version published in JHEP

We study the jet activity that accompanies the production by gluon fusion of a new physics scalar particle decaying into photons at the LHC. In the considered scenarios, both the production and decay mechanisms are governed by loop-induced interactions involving a heavy colored state. We show that the presence of large new physics contributions to the inclusive diphoton invariant-mass spectrum always implies a significant production rate of non-standard diphoton events containing extra hard jets. We investigate the existence of possible handles that could provide a way to obtain information on the underlying physics behind the scalar resonance, and this in a wide mass window., Comment: 7 pages, 10 figures, accepted version to be published in PLB (V2)

My research investigates the premise that fear, anxiety and uncertainty in reason, impact on the essence of the desire to believe in structures, our categorisation of ideology, myself, my approach to artwork and creativity in this contemporary era. This thesis is divided into three different chapters based on the motif “Rational Irregularity”. The first chapter is about the “idea” of antinomy in reason in philosophy and psychoanalysis drawing on Kant, Lacan and neuroscience (nerve science). The second chapter considers the position of art and the artist through Derrida and Danto’s discourses. It further explores the mechanism of art and creativity in the contemporary era using my own interpretation of Lacan’s method of psychoanalysis. The third chapter considers my artworks which are based on the psychological symptom of Sleep Paralysis and the fasting experience through the form of video installation. The reason I focused on the discourses of contemporary philosophy is that I feel the knowledge of theories in any time affects the mechanism of human civilisation in that era. That in turn influences people, the subject and the phenomena of art. This discourse is fluid and the possibility of further discourse emerges from this understanding. Philosophy influenced my way of perceiving phenomena in the world. The understanding of these ideas and the expressions of my artworks became more complex because of those theories and related readings, I entered a problematic realm through this new knowledge. This paper seeks to extrapolate the chaos of these complex thoughts and ideas so I can better understand the mechanism of my art.