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Using cerium nitrate as a cerium source and oil palm leaves (OPL) as the main silica (SiO_2) source, CeO_2–SiO_2(OPL) powder was synthesized via calcination at 900 °C under air conditions. An X-ray diffraction analysis of the as-prepared product revealed the formation of CeO_2 supported on cristobalite SiO_2 along with some other minor element oxides. The Fourier transform infrared spectra showed peaks attributable to the Si–O–Si and Ce–O bonds of the binary oxide. According to a scanning electron microscopy analysis, the solid materials produced via calcination were in aggregated form. The solid, which was easily powdered by grinding in a mortar, was studied for the removal of methylene blue (MB) and phenol compounds from aqueous solution. The results showed that the CeO_2–SiO_2(OPL) material could remove MB up to 62.6% but was ineffective for phenol removal under various conditions.

This article examines discourses that shaped different outcomes for Yemeni refugees in 2018 and Afghan special contributors in 2021 in South Korea. Following the country’s mission to evacuate its Afghan interlocutors in 2021, Afghans are fast‐tracked for social integration through the creation of emergency enforcement ordinances, with South Korean society broadly welcoming them as national heroes and recognizing them as “special contributors” rather than refugees. In contrast, Yemeni refugees arriving in 2018 were subjected to Islamophobic and legal abuse, constructed as potential sex offenders and terrorists, and accused of being fake refugees. In both cases, refugee protections according to South Korea’s 2013 Refugee Law were withheld as Yemenis and Afghans were processed through alternative systems. This article concludes that Muslim refugee issues in South Korea are masculinized and delves into the multi‐faceted complex factors at play when analyzing the differences between the reception of Afghan evacuees and Yemeni refugees in the South Korean context.

This article examines discourses that shaped different outcomes for Yemeni refugees in 2018 and Afghan special contributors in 2021 in South Korea. Following the country’s mission to evacuate its Afghan interlocutors in 2021, Afghans are fast‐tracked for social integration through the creation of emergency enforcement ordinances, with South Korean society broadly welcoming them as national heroes and recognizing them as “special contributors” rather than refugees. In contrast, Yemeni refugees arriving in 2018 were subjected to Islamophobic and legal abuse, constructed as potential sex offenders and terrorists, and accused of being fake refugees. In both cases, refugee protections according to South Korea’s 2013 Refugee Law were withheld as Yemenis and Afghans were processed through alternative systems. This article concludes that Muslim refugee issues in South Korea are masculinized and delves into the multi‐faceted complex factors at play when analyzing the differences between the reception of Afghan evacuees and Yemeni refugees in the South Korean context.

This article examines discourses that shaped different outcomes for Yemeni refugees in 2018 and Afghan special contributors in 2021 in South Korea. Following the country’s mission to evacuate its Afghan interlocutors in 2021, Afghans are fast‐tracked for social integration through the creation of emergency enforcement ordinances, with South Korean society broadly welcoming them as national heroes and recognizing them as “special contributors” rather than refugees. In contrast, Yemeni refugees arriving in 2018 were subjected to Islamophobic and legal abuse, constructed as potential sex offenders and terrorists, and accused of being fake refugees. In both cases, refugee protections according to South Korea’s 2013 Refugee Law were withheld as Yemenis and Afghans were processed through alternative systems. This article concludes that Muslim refugee issues in South Korea are masculinized and delves into the multi‐faceted complex factors at play when analyzing the differences between the reception of Afghan evacuees and Yemeni refugees in the South Korean context.

This article examines discourses that shaped different outcomes for Yemeni refugees in 2018 and Afghan special contributors in 2021 in South Korea. Following the country’s mission to evacuate its Afghan interlocutors in 2021, Afghans are fast‐tracked for social integration through the creation of emergency enforcement ordinances, with South Korean society broadly welcoming them as national heroes and recognizing them as “special contributors” rather than refugees. In contrast, Yemeni refugees arriving in 2018 were subjected to Islamophobic and legal abuse, constructed as potential sex offenders and terrorists, and accused of being fake refugees. In both cases, refugee protections according to South Korea’s 2013 Refugee Law were withheld as Yemenis and Afghans were processed through alternative systems. This article concludes that Muslim refugee issues in South Korea are masculinized and delves into the multi‐faceted complex factors at play when analyzing the differences between the reception of Afghan evacuees and Yemeni refugees in the South Korean context.

This article examines discourses that shaped different outcomes for Yemeni refugees in 2018 and Afghan special contributors in 2021 in South Korea. Following the country’s mission to evacuate its Afghan interlocutors in 2021, Afghans are fast‐tracked for social integration through the creation of emergency enforcement ordinances, with South Korean society broadly welcoming them as national heroes and recognizing them as “special contributors” rather than refugees. In contrast, Yemeni refugees arriving in 2018 were subjected to Islamophobic and legal abuse, constructed as potential sex offenders and terrorists, and accused of being fake refugees. In both cases, refugee protections according to South Korea’s 2013 Refugee Law were withheld as Yemenis and Afghans were processed through alternative systems. This article concludes that Muslim refugee issues in South Korea are masculinized and delves into the multi‐faceted complex factors at play when analyzing the differences between the reception of Afghan evacuees and Yemeni refugees in the South Korean context.

This article examines discourses that shaped different outcomes for Yemeni refugees in 2018 and Afghan special contributors in 2021 in South Korea. Following the country’s mission to evacuate its Afghan interlocutors in 2021, Afghans are fast‐tracked for social integration through the creation of emergency enforcement ordinances, with South Korean society broadly welcoming them as national heroes and recognizing them as “special contributors” rather than refugees. In contrast, Yemeni refugees arriving in 2018 were subjected to Islamophobic and legal abuse, constructed as potential sex offenders and terrorists, and accused of being fake refugees. In both cases, refugee protections according to South Korea’s 2013 Refugee Law were withheld as Yemenis and Afghans were processed through alternative systems. This article concludes that Muslim refugee issues in South Korea are masculinized and delves into the multi‐faceted complex factors at play when analyzing the differences between the reception of Afghan evacuees and Yemeni refugees in the South Korean context.

Accurate predictions of crop yield are critical for developing effective agricultural and food policies at the regional and global scales. We evaluated a machine-learning method, Random Forests (RF), for its ability to predict crop yield responses to climate and biophysical variables at global and regional scales in wheat, maize, and potato in comparison with multiple linear regressions (MLR) serving as a benchmark. We used crop yield data from various sources and regions for model training and testing: 1) gridded global wheat grain yield, 2) maize grain yield from US counties over thirty years, and 3) potato tuber and maize silage yield from the northeastern seaboard region. RF was found highly capable of predicting crop yields and outperformed MLR benchmarks in all performance statistics that were compared. For example, the root mean square errors (RMSE) ranged between 6 and 14% of the average observed yield with RF models in all test cases whereas these values ranged from 14% to 49% for MLR models. Our results show that RF is an effective and versatile machine-learning method for crop yield predictions at regional and global scales for its high accuracy and precision, ease of use, and utility in data analysis. RF may result in a loss of accuracy when predicting the extreme ends or responses beyond the boundaries of the training data.

Accurate predictions of crop yield are critical for developing effective agricultural and food policies at the regional and global scales. We evaluated a machine-learning method, Random Forests (RF), for its ability to predict crop yield responses to climate and biophysical variables at global and regional scales in wheat, maize, and potato in comparison with multiple linear regressions (MLR) serving as a benchmark. We used crop yield data from various sources and regions for model training and testing: 1) gridded global wheat grain yield, 2) maize grain yield from US counties over thirty years, and 3) potato tuber and maize silage yield from the northeastern seaboard region. RF was found highly capable of predicting crop yields and outperformed MLR benchmarks in all performance statistics that were compared. For example, the root mean square errors (RMSE) ranged between 6 and 14% of the average observed yield with RF models in all test cases whereas these values ranged from 14% to 49% for MLR models. Our results show that RF is an effective and versatile machine-learning method for crop yield predictions at regional and global scales for its high accuracy and precision, ease of use, and utility in data analysis. RF may result in a loss of accuracy when predicting the extreme ends or responses beyond the boundaries of the training data.

Sang Gon Lee,1,* Jae Han Jeong,1,* Kyung Min Lee,1 Kyu Ho Jeong,1 Huisuk Yang,2 Miroo Kim,2 Hyungil Jung,2 Sangkil Lee,3 Young Wook Choi11College of Pharmacy, Chung-Ang University, Seoul, South Korea; 2Department of Biotechnology, Yonsei University, Seoul, South Korea; 3College of Pharmacy, Keimyung University, Daegu, South Korea *These authors contributed equally to this workAbstract: Nanostructured lipid carriers (NLCs) were employed to formulate a lipophilic drug into hydrophilic polymeric microneedles (MNs). Hyaluronic acid (HA) was selected as a hydrophilic and bioerodible polymer to fabricate MNs, and nile red (NR) was used as a model lipophilic molecule. NR-loaded NLCs were consolidated into the HA-based MNs to prepare NLC-loaded MNs (NLC-MNs). A dispersion of NLCs was prepared by high-pressure homogenization after dissolving NR in Labrafil and mixing with melted Compritol, resulting in 268 nm NLCs with a polydispersity index of 0.273. The NLC dispersion showed a controlled release of NR over 24 hours, following Hixson–Crowell's cube root law. After mixing the NLC dispersion with the HA solution, the drawing lithography method was used to fabricate NLC-MNs. The length, base diameter, and tip diameter of the NLC-MNs were approximately 350, 380, and 30 µm, respectively. Fluorescence microscopic imaging of the NLC-MNs helped confirm that the NR-loaded NLCs were distributed evenly throughout the MNs. In a skin permeation study performed using a Franz diffusion cell with minipig dorsal skin, approximately 70% of NR was localized in the skin after 24-hour application of NLC-MNs. Confocal laser scanning microscopy (z-series) of the skin at different depths showed strong fluorescence intensity in the epidermal layer, which appeared to spread out radially with the passage of time. This study indicated that incorporation of drug-loaded NLCs into MNs could represent a promising strategy for controlled dermal delivery of lipophilic drugs.Keywo

Sang Gon Lee,1,* Jae Han Jeong,1,* Kyung Min Lee,1 Kyu Ho Jeong,1 Huisuk Yang,2 Miroo Kim,2 Hyungil Jung,2 Sangkil Lee,3 Young Wook Choi11College of Pharmacy, Chung-Ang University, Seoul, South Korea; 2Department of Biotechnology, Yonsei University, Seoul, South Korea; 3College of Pharmacy, Keimyung University, Daegu, South Korea *These authors contributed equally to this workAbstract: Nanostructured lipid carriers (NLCs) were employed to formulate a lipophilic drug into hydrophilic polymeric microneedles (MNs). Hyaluronic acid (HA) was selected as a hydrophilic and bioerodible polymer to fabricate MNs, and nile red (NR) was used as a model lipophilic molecule. NR-loaded NLCs were consolidated into the HA-based MNs to prepare NLC-loaded MNs (NLC-MNs). A dispersion of NLCs was prepared by high-pressure homogenization after dissolving NR in Labrafil and mixing with melted Compritol, resulting in 268 nm NLCs with a polydispersity index of 0.273. The NLC dispersion showed a controlled release of NR over 24 hours, following Hixson–Crowell's cube root law. After mixing the NLC dispersion with the HA solution, the drawing lithography method was used to fabricate NLC-MNs. The length, base diameter, and tip diameter of the NLC-MNs were approximately 350, 380, and 30 µm, respectively. Fluorescence microscopic imaging of the NLC-MNs helped confirm that the NR-loaded NLCs were distributed evenly throughout the MNs. In a skin permeation study performed using a Franz diffusion cell with minipig dorsal skin, approximately 70% of NR was localized in the skin after 24-hour application of NLC-MNs. Confocal laser scanning microscopy (z-series) of the skin at different depths showed strong fluorescence intensity in the epidermal layer, which appeared to spread out radially with the passage of time. This study indicated that incorporation of drug-loaded NLCs into MNs could represent a promising strategy for controlled dermal delivery of lipophilic drugs.Keywo