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1. Bismuth-based perovskite-derivateswith thermal voltage exceeding 40mV/K

Author: Trifiletti, V, Massetti, M, Calloni, A, Luong, S, Pianetti, A, Milita, S, Schroeder, B, Bussetti, G, Binetti, S, Fabiano, S, Fenwick, O, Trifiletti, V., Massetti, M., Calloni, A., Luong, S., Pianetti, A., Milita, S., Schroeder, B. C., Bussetti, G., Binetti, S., Fabiano, S., Fenwick, O., Trifiletti, V, Massetti, M, Calloni, A, Luong, S, Pianetti, A, Milita, S, Schroeder, B, Bussetti, G, Binetti, S, Fabiano, S, Fenwick, O, Trifiletti, V., Massetti, M., Calloni, A., Luong, S., Pianetti, A., Milita, S., Schroeder, B. C., Bussetti, G., Binetti, S., Fabiano, S., and Fenwick, O.
Published: 2024

2. Bismuth-Based Perovskite Derivates with Thermal Voltage Exceeding 40 mV/K

Author: Trifiletti, V, Massetti, M, Calloni, A, Luong, S, Pianetti, A, Milita, S, Schroeder, B, Bussetti, G, Binetti, S, Fabiano, S, Fenwick, O, Trifiletti, Vanira, Massetti, Matteo, Calloni, Alberto, Luong, Sally, Pianetti, Andrea, Milita, Silvia, Schroeder, Bob C., Bussetti, Gianlorenzo, Binetti, Simona, Fabiano, Simone, Fenwick, Oliver, Trifiletti, V, Massetti, M, Calloni, A, Luong, S, Pianetti, A, Milita, S, Schroeder, B, Bussetti, G, Binetti, S, Fabiano, S, Fenwick, O, Trifiletti, Vanira, Massetti, Matteo, Calloni, Alberto, Luong, Sally, Pianetti, Andrea, Milita, Silvia, Schroeder, Bob C., Bussetti, Gianlorenzo, Binetti, Simona, Fabiano, Simone, and Fenwick, Oliver
Abstract: Heat is an inexhaustible source of energy, and it can be exploited by thermoelectronics to produce electrical power or electrical responses. The search for a low-cost thermoelectric material that could achieve high efficiencies and can also be straightforwardly scalable has turned significant attention to the halide perovskite family. Here, we report the thermal voltage response of bismuth-based perovskite derivates and suggest a path to increase the electrical conductivity by applying chalcogenide doping. The films were produced by drop-casting or spin coating, and sulfur was introduced in the precursor solution using bismuth triethylxanthate. The physical-chemical analysis confirms the substitution. The sulfur introduction caused resistivity reduction by 2 orders of magnitude, and the thermal voltage exceeded 40 mV K-1 near 300 K in doped and undoped bismuth-based perovskite derivates. X-ray diffraction, Raman spectroscopy, and grazing-incidence wide-angle X-ray scattering were employed to confirm the structure. X-ray photoelectron spectroscopy, elemental analysis, scanning electron microscopy, and energy-dispersive X-ray spectroscopy were employed to study the composition and morphology of the produced thin films. UV-visible absorbance, photoluminescence, inverse photoemission, and ultraviolet photoelectron spectroscopies have been used to investigate the energy band gap.
Published: 2024

3. Bi-based perovskite-derivates with significant Seebeck coefficients

Author: Trifiletti, V, Massetti, M, Calloni, A, Luong, S, Schroeder, B, Bussetti, G, Binetti, S, Fabiano, S, Fenwick, O, Vanira Trifiletti, Matteo Massetti, Alberto Calloni, Sally Luong, Bob C. Schroeder, Gianlorenzo Bussetti, Simona Binetti, Simone Fabiano, Oliver Fenwick, Trifiletti, V, Massetti, M, Calloni, A, Luong, S, Schroeder, B, Bussetti, G, Binetti, S, Fabiano, S, Fenwick, O, Vanira Trifiletti, Matteo Massetti, Alberto Calloni, Sally Luong, Bob C. Schroeder, Gianlorenzo Bussetti, Simona Binetti, Simone Fabiano, and Oliver Fenwick
Abstract: Heat is an inexhaustible source of energy and stimuli. Thermoelectric generators and thermal sensors can produce power or an electrical signal, harvesting the waste heat. The search for a material that could be low cost, guarantee high efficiencies and be directly scalable has drawn attention to the family of halide perovskites. Here, we report bismuth-based perovskite-derivates to be used in thermal harvesting applications and suggest a path to increase the electrical conductivity by applying the mixed-anion approach, where the halide was partially substituted with sulphur to reduce the electrical resistivity. The layers were produced by drop-casting or spin coating; bismuth tri-ethylxanthate has been successfully used as a sulphur source. The Seebeck coefficients measured were higher than 40 mV K-1 in doped and undoped bismuth-based perovskite-derivates. Here, we present an extensive result discussion, based on Raman spectroscopy, X-ray diffraction, UV–visible characterization, ultra-violet, X-ray and inverse photoemission spectroscopies, SEM and EDS analysis. The significant Seebeck coefficient and the micrometre-sized sample dimensions make these compounds highly attractive for heat-flow sensing applications and, above all, for those technologies requiring miniaturised and flexible devices.
Published: 2023

4. Thinness and its variations on some graph families and coloring graphs of bounded thinness

Author: Bonomo-Braberman, Flavia, Brandwein, Eric, Oliveira, Fabiano S., Sampaio Jr., Moysés S., Sansone, Agustin, Szwarcfiter, Jayme L., Bonomo-Braberman, Flavia, Brandwein, Eric, Oliveira, Fabiano S., Sampaio Jr., Moysés S., Sansone, Agustin, and Szwarcfiter, Jayme L.
Abstract: Interval graphs and proper interval graphs are well known graph classes, for which several generalizations have been proposed in the literature. In this work, we study the (proper) thinness, and several variations, for the classes of cographs, crowns graphs and grid graphs. We provide the exact values for several variants of thinness (proper, independent, complete, precedence, and combinations of them) for the crown graphs $CR_n$. For cographs, we prove that the precedence thinness can be determined in polynomial time. We also improve known bounds for the thinness of $n \times n$ grids $GR_n$ and $m \times n$ grids $GR_{m,n}$, proving that $\left \lceil \frac{n-1}{3} \right \rceil \leq \mbox{thin}(GR_n) \leq \left \lceil \frac{n+1}{2} \right \rceil$. Regarding the precedence thinness, we prove that $\mbox{prec-thin}(GR_{n,2}) = \left \lceil \frac{n+1}{2} \right \rceil$ and that $\left \lceil \frac{n-1}{3} \right \rceil \left \lceil\frac{n-1}{2} \right \rceil + 1 \leq \mbox{prec-thin}(GR_n) \leq \left \lceil\frac{n-1}{2} \right \rceil^2+1$. As applications, we show that the $k$-coloring problem is NP-complete for precedence $2$-thin graphs and for proper $2$-thin graphs, when $k$ is part of the input. On the positive side, it is polynomially solvable for precedence proper $2$-thin graphs, given the order and partition.
Published: 2023

5. Maximum Cut on Interval Graphs of Interval Count Four Is NP-Complete

Author: Celina M. H. de Figueiredo and Alexsander A. de Melo and Fabiano S. Oliveira and Ana Silva, de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., Silva, Ana, Celina M. H. de Figueiredo and Alexsander A. de Melo and Fabiano S. Oliveira and Ana Silva, de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., and Silva, Ana
Abstract: The computational complexity of the MaxCut problem restricted to interval graphs has been open since the 80’s, being one of the problems proposed by Johnson on his Ongoing Guide to NP-completeness, and has been settled as NP-complete only recently by Adhikary, Bose, Mukherjee and Roy. On the other hand, many flawed proofs of polynomiality for MaxCut on the more restrictive class of unit/proper interval graphs (or graphs with interval count 1) have been presented along the years, and the classification of the problem is still not known. In this paper, we present the first NP-completeness proof for MaxCut when restricted to interval graphs with bounded interval count, namely graphs with interval count 4.
Published: 2021
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6. Sequential Doping of Ladder-Type Conjugated Polymers for Thermally Stable n-Type Organic Conductors

Author: Wang, S, Ruoko, T, Wang, G, Riera-Galindo, S, Hultmark, S, Puttisong, Y, Moro, F, Yan, H, Chen, W, Berggren, M, Muller, C, Fabiano, S, Wang S., Ruoko T. -P., Wang G., Riera-Galindo S., Hultmark S., Puttisong Y., Moro F., Yan H., Chen W. M., Berggren M., Muller C., Fabiano S., Wang, S, Ruoko, T, Wang, G, Riera-Galindo, S, Hultmark, S, Puttisong, Y, Moro, F, Yan, H, Chen, W, Berggren, M, Muller, C, Fabiano, S, Wang S., Ruoko T. -P., Wang G., Riera-Galindo S., Hultmark S., Puttisong Y., Moro F., Yan H., Chen W. M., Berggren M., Muller C., and Fabiano S.
Abstract: Doping of organic semiconductors is a powerful tool to optimize the performance of various organic (opto)electronic and bioelectronic devices. Despite recent advances, the low thermal stability of the electronic properties of doped polymers still represents a significant obstacle to implementing these materials into practical applications. Hence, the development of conducting doped polymers with excellent long-term stability at elevated temperatures is highly desirable. Here, we report on the sequential doping of the ladder-type polymer poly(benzimidazobenzophenanthroline) (BBL) with a benzimidazole-based dopant (i.e., N-DMBI). By combining electrical, UV-vis/infrared, X-ray diffraction, and electron paramagnetic resonance measurements, we quantitatively characterized the conductivity, Seebeck coefficient, spin density, and microstructure of the sequentially doped polymer films as a function of the thermal annealing temperature. Importantly, we observed that the electrical conductivity of N-DMBI-doped BBL remains unchanged even after 20 h of heating at 190 °C. This finding is remarkable and of particular interest for organic thermoelectrics.
Published: 2020

7. Sequential Doping of Ladder-Type Conjugated Polymers for Thermally Stable n-Type Organic Conductors

Author: Wang, S, Ruoko, T, Wang, G, Riera-Galindo, S, Hultmark, S, Puttisong, Y, Moro, F, Yan, H, Chen, W, Berggren, M, Muller, C, Fabiano, S, Wang S., Ruoko T. -P., Wang G., Riera-Galindo S., Hultmark S., Puttisong Y., Moro F., Yan H., Chen W. M., Berggren M., Muller C., Fabiano S., Wang, S, Ruoko, T, Wang, G, Riera-Galindo, S, Hultmark, S, Puttisong, Y, Moro, F, Yan, H, Chen, W, Berggren, M, Muller, C, Fabiano, S, Wang S., Ruoko T. -P., Wang G., Riera-Galindo S., Hultmark S., Puttisong Y., Moro F., Yan H., Chen W. M., Berggren M., Muller C., and Fabiano S.
Abstract: Doping of organic semiconductors is a powerful tool to optimize the performance of various organic (opto)electronic and bioelectronic devices. Despite recent advances, the low thermal stability of the electronic properties of doped polymers still represents a significant obstacle to implementing these materials into practical applications. Hence, the development of conducting doped polymers with excellent long-term stability at elevated temperatures is highly desirable. Here, we report on the sequential doping of the ladder-type polymer poly(benzimidazobenzophenanthroline) (BBL) with a benzimidazole-based dopant (i.e., N-DMBI). By combining electrical, UV-vis/infrared, X-ray diffraction, and electron paramagnetic resonance measurements, we quantitatively characterized the conductivity, Seebeck coefficient, spin density, and microstructure of the sequentially doped polymer films as a function of the thermal annealing temperature. Importantly, we observed that the electrical conductivity of N-DMBI-doped BBL remains unchanged even after 20 h of heating at 190 °C. This finding is remarkable and of particular interest for organic thermoelectrics.
Published: 2020

8. Precise tuning of interlayer electronic coupling in layered conductive metal-organic frameworks

Author: Lu Y., Zhang Y., Yang C.-Y., Revuelta S., Qi H., Huang C., Jin W., Li Z., Vega-Mayoral V., Liu Y., Huang X., Pohl D., Položij M., Zhou S., Cánovas, Enrique, Heine T., Fabiano S., Feng X., Dong R., Lu Y., Zhang Y., Yang C.-Y., Revuelta S., Qi H., Huang C., Jin W., Li Z., Vega-Mayoral V., Liu Y., Huang X., Pohl D., Položij M., Zhou S., Cánovas, Enrique, Heine T., Fabiano S., Feng X., and Dong R.
Published: 2022

9. Natural Product Betulin-Based Insulating Polymer Filler in Organic Solar Cells

Author: Zhang, Q., Zhang, H., Wu, Z., Wang, C., Zhang, R., Yang, C., Gao, F., Fabiano, S., Woo, H. Y., Ek, Monica, Liu, X., Fahlman, M., Zhang, Q., Zhang, H., Wu, Z., Wang, C., Zhang, R., Yang, C., Gao, F., Fabiano, S., Woo, H. Y., Ek, Monica, Liu, X., and Fahlman, M.
Abstract: Introduction of filler materials into organic solar cells (OSCs) are a promising strategy to improve device performance and thermal/mechanical stability. However, the complex interactions between the state-of-the-art OSC materials and filler require careful selection of filler materials and OSC fabrication to achieve lower cost and improved performance. In this work, the introduction of a natural product betulin-based insulating polymer as filler in various OSCs is investigated. Donor–acceptor–insulator ternary OSCs are developed with improved open-circuit voltage (Voc) due to decreased trap-assisted recombination. Furthermore, filler-induced vertical phase separation due to mismatched surface energy can strongly affect charge collection at the bottom interface and limit the filler ratio. A quasi-bilayer strategy is used in all-polymer systems to circumvent this problem. Herein, the variety of filler materials in OSCs to biomass is broadened, and the filler strategy is made a feasible and promising strategy toward highly efficient, eco, and low-cost OSCs., QC 20230308
Published: 2022
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10. Precise tuning of interlayer electronic coupling in layered conductive metal-organic frameworks

Author: Lu, Y., Zhang, Y., Yang, C.-Y., Revuelta, S., Qi, H., Huang, C., Jin, W., Li, Z., Vega-Mayoral, V., Liu, Y., Huang, X., Pohl, D., Položij, M., (0000-0002-4885-799X) Zhou, S., Cánovas, E., Heine, T., Fabiano, S., Feng, X., Dong, R., Lu, Y., Zhang, Y., Yang, C.-Y., Revuelta, S., Qi, H., Huang, C., Jin, W., Li, Z., Vega-Mayoral, V., Liu, Y., Huang, X., Pohl, D., Položij, M., (0000-0002-4885-799X) Zhou, S., Cánovas, E., Heine, T., Fabiano, S., Feng, X., and Dong, R.
Abstract: Two-dimensional conjugated metal-organic frameworks (2D c-MOFs) have attracted increasing interests for (opto)-electronics and spintronics. They generally consist of van der Waals stacked layers and exhibit layer-depended electronic properties. While considerable efforts have been made to regulate the charge transport within a layer, precise control of electronic coupling between layers has not yet been achieved. Herein, we report a strategy to precisely tune interlayer charge transport in 2D c-MOFs via side-chain induced control of the layer spacing. We design hexaiminotriindole ligands allowing programmed functionalization with tailored alkyl chains (HATI_CX, X = 1,3,4; X refers to the carbon numbers of the alkyl chains) for the synthesis of semiconducting Ni3(HATI_CX)2. The layer spacing of these MOFs can be precisely varied from 3.40 to 3.70 Å, leading to widened band gap, suppressed carrier mobilities, and significant improvement of the Seebeck coefficient. With this demonstration, we further achieve a record-high thermoelectric power factor of 68 ± 3 nW m−1 K−2 in Ni3(HATI_C3)2, superior to the reported holes-dominated MOFs.
Published: 2022

11. Edge Intersection Graphs of Paths on a Triangular Grid

Author: de Luca, Vitor T. F., Mazzoleni, María Pía, Oliveira, Fabiano S., Santos, Tanilson D., Szwarcfiter, Jayme L., de Luca, Vitor T. F., Mazzoleni, María Pía, Oliveira, Fabiano S., Santos, Tanilson D., and Szwarcfiter, Jayme L.
Abstract: We introduce a new class of intersection graphs, the edge intersection graphs of paths on a triangular grid, called EPGt graphs. We show similarities and differences from this new class to the well-known class of EPG graphs. A turn of a path at a grid point is called a bend. An EPGt representation in which every path has at most $k$ bends is called a B$_k$-EPGt representation and the corresponding graphs are called B$_k$-EPGt graphs. We provide examples of B$_{2}$-EPG graphs that are B$_{1}$-EPGt. We characterize the representation of cliques with three vertices and chordless 4-cycles in B$_{1}$-EPGt representations. We also prove that B$_{1}$-EPGt graphs have Strong Helly number $3$. Furthermore, we prove that B$_{1}$-EPGt graphs are $7$-clique colorable., Comment: 19 pages, 12 figures
Published: 2022

12. MaxCut on Permutation Graphs is NP-complete

Author: de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., Silva, Ana, de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., and Silva, Ana
Abstract: In this paper, we prove that the MaxCut problem is NP-complete on permutation graphs, settling a long-standing open problem that appeared in the 1985 column of the "Ongoing Guide to NP-completeness" by David S. Johnson.
Published: 2022

13. Maximum Cut on Interval Graphs of Interval Count Four Is NP-Complete

Author: de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., Silva, Ana, de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., and Silva, Ana
Published: 2021
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14. Optimal allocation of proton therapy slots in combined proton-photon radiotherapy

Author: Loizeau, N., Fabiano, S., Papp, D., (0000-0002-8178-3144) Stützer, K., Jakobi, A., Bandurska-Luque, A., (0000-0001-9550-9050) Troost, E. G. C., (0000-0003-4261-4214) Richter, C., Unkelbach, J., Loizeau, N., Fabiano, S., Papp, D., (0000-0002-8178-3144) Stützer, K., Jakobi, A., Bandurska-Luque, A., (0000-0001-9550-9050) Troost, E. G. C., (0000-0003-4261-4214) Richter, C., and Unkelbach, J.
Abstract: Purpose: Proton therapy is a limited resource, which is not available to all patients who may benefit from it. We investigate combined proton-photon treatments, in which some fractions are delivered with protons and the remaining fractions with photons, as an approach to maximize the benefit of limited proton therapy resources at a population level. Methods: To quantify differences in normal tissue complication probability (NTCP) between protons and photons, we consider a cohort of 45 head-and-neck cancer patients for which IMRT and IMPT plans were previously created, in combination with NTCP models for xerostomia and dysphagia considered in the Netherlands for proton patient selection. Assuming limited availability of proton slots, we develop methods to optimally assign proton fractions in combined proton-photon treatments to minimize the average NTCP on a population level. Such combined treatments are compared to patient selection strategies in which patients are assigned to single-modality proton or photon treatments. Results: There is a benefit of combined proton-photon treatments over patient selection due to the nonlinearity of NTCP functions, i.e. the initial proton fractions are the most beneficial whereas additional proton fractions have a decreasing benefit when a flatter part of the NTCP curve is reached. This effect was small for the patient cohort and NTCP models considered, but may be larger if dose-response relationships are better known. In addition, when proton slots are limited, patient selection methods face a tradeoff between leaving slots unused and blocking slots for future patients who may have a larger benefit. Combined proton-photon treatments with flexible proton slot assignment provide a method to make optimal use of all available resources. Conclusions: Combined proton-photon treatments allow for a better utilization of limited proton therapy resources. The benefit over patient selection schemes depends on the NTCP models and the dose dif
Published: 2021

15. Optimal allocation of proton therapy slots in combined proton-photon radiotherapy

Author: Loizeau, N., Fabiano, S., Papp, D., (0000-0002-8178-3144) Stützer, K., Jakobi, A., Bandurska-Luque, A., (0000-0001-9550-9050) Troost, E. G. C., (0000-0003-4261-4214) Richter, C., Unkelbach, J., Loizeau, N., Fabiano, S., Papp, D., (0000-0002-8178-3144) Stützer, K., Jakobi, A., Bandurska-Luque, A., (0000-0001-9550-9050) Troost, E. G. C., (0000-0003-4261-4214) Richter, C., and Unkelbach, J.
Abstract: Purpose: Proton therapy is a limited resource, which is not available to all patients who may benefit from it. We investigate combined proton-photon treatments, in which some fractions are delivered with protons and the remaining fractions with photons, as an approach to maximize the benefit of limited proton therapy resources at a population level. Methods: To quantify differences in normal tissue complication probability (NTCP) between protons and photons, we consider a cohort of 45 head-and-neck cancer patients for which IMRT and IMPT plans were previously created, in combination with NTCP models for xerostomia and dysphagia considered in the Netherlands for proton patient selection. Assuming limited availability of proton slots, we develop methods to optimally assign proton fractions in combined proton-photon treatments to minimize the average NTCP on a population level. Such combined treatments are compared to patient selection strategies in which patients are assigned to single-modality proton or photon treatments. Results: There is a benefit of combined proton-photon treatments over patient selection due to the nonlinearity of NTCP functions, i.e. the initial proton fractions are the most beneficial whereas additional proton fractions have a decreasing benefit when a flatter part of the NTCP curve is reached. This effect was small for the patient cohort and NTCP models considered, but may be larger if dose-response relationships are better known. In addition, when proton slots are limited, patient selection methods face a tradeoff between leaving slots unused and blocking slots for future patients who may have a larger benefit. Combined proton-photon treatments with flexible proton slot assignment provide a method to make optimal use of all available resources. Conclusions: Combined proton-photon treatments allow for a better utilization of limited proton therapy resources. The benefit over patient selection schemes depends on the NTCP models and the dose dif
Published: 2021

16. Thinness of product graphs

Author: Bonomo-Braberman, Flavia, Gonzalez, Carolina L., Oliveira, Fabiano S., Sampaio Jr., Moysés S., Szwarcfiter, Jayme L., Bonomo-Braberman, Flavia, Gonzalez, Carolina L., Oliveira, Fabiano S., Sampaio Jr., Moysés S., and Szwarcfiter, Jayme L.
Abstract: The thinness of a graph is a width parameter that generalizes some properties of interval graphs, which are exactly the graphs of thinness one. Many NP-complete problems can be solved in polynomial time for graphs with bounded thinness, given a suitable representation of the graph. In this paper we study the thinness and its variations of graph products. We show that the thinness behaves "well" in general for products, in the sense that for most of the graph products defined in the literature, the thinness of the product of two graphs is bounded by a function (typically product or sum) of their thinness, or of the thinness of one of them and the size of the other. We also show for some cases the non-existence of such a function., Comment: 45 pages. arXiv admin note: text overlap with arXiv:1704.00379
Published: 2020
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17. Precedence thinness in graphs

Author: Bonomo-Braberman, Flavia, Oliveira, Fabiano S., Sampaio Jr., Moysés S., Szwarcfiter, Jayme L., Bonomo-Braberman, Flavia, Oliveira, Fabiano S., Sampaio Jr., Moysés S., and Szwarcfiter, Jayme L.
Abstract: Interval and proper interval graphs are very well-known graph classes, for which there is a wide literature. As a consequence, some generalizations of interval graphs have been proposed, in which graphs in general are expressed in terms of $k$ interval graphs, by splitting the graph in some special way. As a recent example of such an approach, the classes of $k$-thin and proper $k$-thin graphs have been introduced generalizing interval and proper interval graphs, respectively. The complexity of the recognition of each of these classes is still open, even for fixed $k \geq 2$. In this work, we introduce a subclass of $k$-thin graphs (resp. proper $k$-thin graphs), called precedence $k$-thin graphs (resp. precedence proper $k$-thin graphs). Concerning partitioned precedence $k$-thin graphs, we present a polynomial time recognition algorithm based on $PQ$-trees. With respect to partitioned precedence proper $k$-thin graphs, we prove that the related recognition problem is \NP-complete for an arbitrary $k$ and polynomial-time solvable when $k$ is fixed. Moreover, we present a characterization for these classes based on threshold graphs., Comment: 33 pages
Published: 2020
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18. Linear-time Algorithms for Eliminating Claws in Graphs

Author: Bonomo-Braberman, Flavia, Nascimento, Julliano R., Oliveira, Fabiano S., Souza, Uéverton S., Szwarcfiter, Jayme L., Bonomo-Braberman, Flavia, Nascimento, Julliano R., Oliveira, Fabiano S., Souza, Uéverton S., and Szwarcfiter, Jayme L.
Abstract: Since many NP-complete graph problems have been shown polynomial-time solvable when restricted to claw-free graphs, we study the problem of determining the distance of a given graph to a claw-free graph, considering vertex elimination as measure. CLAW-FREE VERTEX DELETION (CFVD) consists of determining the minimum number of vertices to be removed from a graph such that the resulting graph is claw-free. Although CFVD is NP-complete in general and recognizing claw-free graphs is still a challenge, where the current best algorithm for a graph $G$ has the same running time of the best algorithm for matrix multiplication, we present linear-time algorithms for CFVD on weighted block graphs and weighted graphs with bounded treewidth. Furthermore, we show that this problem can be solved in linear time by a simpler algorithm on forests, and we determine the exact values for full $k$-ary trees. On the other hand, we show that CLAW-FREE VERTEX DELETION is NP-complete even when the input graph is a split graph. We also show that the problem is hard to approximate within any constant factor better than $2$, assuming the Unique Games Conjecture., Comment: 20 pages
Published: 2020
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19. Maximum cut on interval graphs of interval count four is NP-complete

Author: de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., Silva, Ana, de Figueiredo, Celina M. H., de Melo, Alexsander A., Oliveira, Fabiano S., and Silva, Ana
Abstract: The computational complexity of the MaxCut problem restricted to interval graphs has been open since the 80's, being one of the problems proposed by Johnson on his Ongoing Guide to NP-completeness, and has been settled as NP-complete only recently by Adhikary, Bose, Mukherjee and Roy. On the other hand, many flawed proofs of polynomiality for MaxCut on the more restrictive class of unit/proper interval graphs (or graphs with interval count 1) have been presented along the years, and the classification of the problem is still unknown. In this paper, we present the first NP-completeness proof for MaxCut when restricted to interval graphs with bounded interval count, namely graphs with interval count 4.
Published: 2020

20. Combined proton-photon treatments: How can limited proton slots be optimally distributed over a patient cohort?

Author: Loizeau, N., Fabiano, S., Papp, D., Jakobi, A., Bandurska-Luque, A., (0000-0002-8178-3144) Stützer, K., Richter, C., Unkelbach, J., Loizeau, N., Fabiano, S., Papp, D., Jakobi, A., Bandurska-Luque, A., (0000-0002-8178-3144) Stützer, K., Richter, C., and Unkelbach, J.
Abstract: Introduction: Although rapidly growing, proton therapy is a limited resource, which is not available to all the patients who may benefit from it. In this study, we investigate if combined proton-photon treatments, in which some fractions are delivered with protons and the rest with photons, improve on single-modality treatments. Combined treatment can be motivated by the consideration that, on the convex part of the NTCP curve, the first proton fractions are the most beneficial. We assume a situation of limited proton slot availability and develop methods to distribute those limited slots over a patient cohort optimally in order to optimize the benefit of proton therapy at a population level. Material and Methods: We consider a cohort of 45 head and neck cancer patients for which IMRT and IMPT plans were previously created [1]. NTCP models for relevant side effects (e.g. xerostomia) were used to calculate the NTCP values for all the plans. We investigate a 30 fraction simultaneous integrated boost (SIB) scheme (1.8 Gy to the PTV, 2.3 Gy to the GTV) and a sequential boost (SEQ) scheme with a 25 fraction base plan (2 Gy to the PTV) and a 10 fraction boost plan (2 Gy to the GTV). Under the assumption that, due to limited resources, only a small percentage of the total number of fractions can be delivered with protons, an integer programming algorithm was applied to determine the optimal number of proton fractions per patient that minimizes the total number of expected complications over the patient cohort. Results: Figure 1a shows the NTCP values for xerostomia in the IMRT and IMPT plans for the SIB scheme for all patients. Figures 1b shows the optimal allocation of proton slots for the situation where 20% of all fractions are delivered with protons. The patients with the highest ∆NTCP value (IMRT-IMPT) receive the largest number of proton fractions. The average xerostomia NTCP value from all 45 patients for the SIB scheme for combined treatment equals 13.0%. For the s
Published: 2019

21. Combined proton-photon treatments: How can limited proton slots be optimally distributed over a patient cohort?

Author: Loizeau, N., Fabiano, S., Papp, D., Jakobi, A., Bandurska-Luque, A., (0000-0002-8178-3144) Stützer, K., (0000-0003-4261-4214) Richter, C., Unkelbach, J., Loizeau, N., Fabiano, S., Papp, D., Jakobi, A., Bandurska-Luque, A., (0000-0002-8178-3144) Stützer, K., (0000-0003-4261-4214) Richter, C., and Unkelbach, J.
Abstract: Introduction: Although rapidly growing, proton therapy is a limited resource, which is not available to all the patients who may benefit from it. In this study, we investigate if combined proton-photon treatments, in which some fractions are delivered with protons and the rest with photons, improve on single-modality treatments. Combined treatment can be motivated by the consideration that, on the convex part of the NTCP curve, the first proton fractions are the most beneficial. We assume a situation of limited proton slot availability and develop methods to distribute those limited slots over a patient cohort optimally in order to optimize the benefit of proton therapy at a population level. Material and Methods: We consider a cohort of 45 head and neck cancer patients for which IMRT and IMPT plans were previously created [1]. NTCP models for relevant side effects (e.g. xerostomia) were used to calculate the NTCP values for all the plans. We investigate a 30 fraction simultaneous integrated boost (SIB) scheme (1.8 Gy to the PTV, 2.3 Gy to the GTV) and a sequential boost (SEQ) scheme with a 25 fraction base plan (2 Gy to the PTV) and a 10 fraction boost plan (2 Gy to the GTV). Under the assumption that, due to limited resources, only a small percentage of the total number of fractions can be delivered with protons, an integer programming algorithm was applied to determine the optimal number of proton fractions per patient that minimizes the total number of expected complications over the patient cohort. Results: Figure 1a shows the NTCP values for xerostomia in the IMRT and IMPT plans for the SIB scheme for all patients. Figures 1b shows the optimal allocation of proton slots for the situation where 20% of all fractions are delivered with protons. The patients with the highest ∆NTCP value (IMRT-IMPT) receive the largest number of proton fractions. The average xerostomia NTCP value from all 45 patients for the SIB scheme for combined treatment equals 13.0%. For the s
Published: 2019

22. Effectiveness of First-Line Bevacizumab in Metastatic Colorectal Cancer: The Observational Cohort Study GRETA

Author: Franchi, M, Barni, S, Tagliabue, G, Ricci, P, Mazzucco, W, Tumino, R, Caputo, A, Corrao, G, Fabiano, S, Barigelletti, G, Gatti, L, Cusimano, R, Vitale, F, Giurdanella, M, Rollo, P, Spata, E, De Ceglie, M, Franchi, Matteo, Barni, Sandro, TAGLIABUE, GIOVANNA, Ricci, Paolo, Mazzucco, Walter, Tumino, Rosario, Caputo, Antonietta, Corrao, Giovanni, Tagliabue, Giovanna, Fabiano, Sabrina, Barigelletti, Giulio, Gatti, Lucina, Cusimano, Rosanna, Vitale, Francesco, Giurdanella, Maria Concetta, Rollo, Patrizia Concetta, Spata, Eugenia, De Ceglie, Maria Carolina, Franchi, M, Barni, S, Tagliabue, G, Ricci, P, Mazzucco, W, Tumino, R, Caputo, A, Corrao, G, Fabiano, S, Barigelletti, G, Gatti, L, Cusimano, R, Vitale, F, Giurdanella, M, Rollo, P, Spata, E, De Ceglie, M, Franchi, Matteo, Barni, Sandro, TAGLIABUE, GIOVANNA, Ricci, Paolo, Mazzucco, Walter, Tumino, Rosario, Caputo, Antonietta, Corrao, Giovanni, Tagliabue, Giovanna, Fabiano, Sabrina, Barigelletti, Giulio, Gatti, Lucina, Cusimano, Rosanna, Vitale, Francesco, Giurdanella, Maria Concetta, Rollo, Patrizia Concetta, Spata, Eugenia, and De Ceglie, Maria Carolina
Abstract: Background: Scant real-world data exist on the clinical outcomes associated with the use of bevacizumab-containing chemotherapy (B+CT) in patients with metastatic colorectal cancer (mCRC). The primary objective of the GRETA cohort study was to compare the overall survival (OS) of patients with mCRC treated with first-line B+CT versus chemotherapy (CT) alone, in an Italian clinical practice setting. Materials and Methods: Incident patients with mCRC were identified during the period 2010–2012 from five population-based cancer registries in Italy. Cases were linked to regional health care utilization databases to obtain the entire spectrum of health services provided to each patient. Patients starting a first-line treatment with B+CT or CT alone within 90 days from the diagnosis were included in the study cohort. A propensity score (PS) method was applied to account for residual confounding. Results: Of 480 patients with mCRC included in the study cohort, 21.0 received first-line B+CT, and 79.0% received CT. Patients receiving B+CT were younger (p <.001) and underwent surgery more frequently (p =.001). The median OS was 22.5 and 14.6 months for B+CT and CT, respectively (p =.011). The corresponding hazard ratios adjusted by multivariate modeling and PS matched analysis were 0.82 (95% confidence interval [CI], 0.62–1.08) and 0.86 (95% CI, 0.56–1.33), respectively. Similar results were observed after subgrouping by age and surgery. Conclusion: In this Italian real-world setting of unselected mCRC, the OS of patients treated with B+CT was consistent with previous observational and patient-registry studies. However, definitive evidence of an improvement in OS cannot be drawn. Implications for Practice: Bevacizumab is a well-established first-line treatment for metastatic colorectal cancer. However, there is scarce evidence in the literature about its effectiveness in clinical practice. Evaluating this topic should be of interest for both clinicians and regulatory agenc
Published: 2019

23. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Author: Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, Wilson, Richard K., Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, and Wilson, Richard K.
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017
Full Text: View/download PDF

24. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Author: Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, Wilson, Richard K., Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, and Wilson, Richard K.
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017
Full Text: View/download PDF

25. Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Author: Adema, Coen M, Adema, Coen M, Hillier, LaDeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F, di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel, Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L, Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T, Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J, Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, Ryan, Kathryn M, Adema, Coen M, Adema, Coen M, Hillier, LaDeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F, di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel, Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L, Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T, Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J, Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, and Ryan, Kathryn M
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017

26. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Author: Adema, C.M. (Coen M.), Hillier, L.W. (LaDeana W.), Jones, C.S. (Catherine S.), Loker, E.S. (Eric S.), Knight, M. (Matty), Minx, P. (Patrick), Oliveira, G. (Guilherme), Raghavan, N. (Nithya), Shedlock, A. (Andrew), Do Amaral, L.R. (Laurence Rodrigues), Arican-Goktas, H.D. (Halime D.), Assis, J.G. (Juliana G.), Baba, E.H. (Elio Hideo), Baron, O.L. (Olga L.), Bayne, C.J. (Christopher J.), Bickham-Wright, U. (Utibe), Biggar, K.K. (Kyle K.), Blouin, M. (Michael), Bonning, B.C. (Bryony C.), Botka, C. (Chris), Bridger, J.M. (Joanna M.), Buckley, K.M. (Katherine M.), Buddenborg, S.K. (Sarah K.), Lima Caldeira, R. (Roberta), Carleton, J. (Julia), Carvalho, O.S. (Omar S.), Castillo, M.G. (Maria G.), Chalmers, I.W. (Iain W.), Christensens, M. (Mikkel), Clifton, S. (Sandra), Cosseau, C. (Celine), Coustau, C. (Christine), Cripps, R.M. (Richard M.), Cuesta-Astroz, Y. (Yesid), Cummins, S.F. (Scott F.), DI Stephano, L. (Leon), DInguirard, N. (Nathalie), Duval, D. (David), Emrich, S. (Scott), Feschotte, C. (Cédric), Feyereisen, R. (Rene), Fitzgerald, P. (Peter), Fronick, C. (Catrina), Fulton, L. (Lucinda), Galinier, R. (Richard), Gava, S.G. (Sandra G.), Geusz, M. (Michael), Geyer, K.K. (Kathrin K.), Giraldo-Calderón, G.I. (Gloria I.), De Souza Gomes, M. (Matheus), Gordy, M.A. (Michelle A.), Gourbal, B. (Benjamin), Grunau, C. (Christoph), Hanington, P.C. (Patrick C.), Hoffmann, K.F. (Karl F.), Hughes, D. (Daniel), Humphries, J. (Judith), Jackson, D.J. (Daniel J.), Jannotti-Passos, L.K. (Liana K.), De Jesus Jeremias, W. (Wander), Jobling, S. (Susan), Kamel, B. (Bishoy), Kapusta, A. (Aurélie), Kaur, S. (Satwant), Koene, J.M. (Joris M.), Kohn, A.B. (Andrea B.), Lawson, D. (Dan), Lawton, S.P. (Scott P), Liang, D. (Di), Limpanont, Y. (Yanin), Liu, S. (Sijun), Lockyer, A.E. (Anne E.), Lovato, T.L. (TyAnna L.), Ludolf, F. (Fernanda), Magrini, V. (Vince), McManus, D.P. (Donald P.), Medina, M. (Monica), Misra, M. (Milind), Mitta, G. (Guillaume), Mkoji, G.M. (Gerald M.), Montague, M.J. (Michael J.), Montelongo, C. (Cesar), Moroz, L.L. (Leonid L.), Munoz-Torres, M.C. (Monica C.), Niazi, U. (Umar), Noble, L.R. (Leslie R.), Oliveira, F.S. (Francislon S.), Pais, F.S. (Fabiano S.), Papenfuss, A.T. (Anthony T.), Peace, R. (Rob), Pena, J.J. (Janeth J.), Pila, E.A. (Emmanuel A.), Quelais, T. (Titouan), Raney, B.J. (Brian J.), Rast, J.P. (Jonathan P.), Rollinson, D. (David), Rosse, I.C. (Izinara C.), Rotgans, B. (Bronwyn), Routledge, E.J. (Edwin J.), Ryan, K.M. (Kathryn M.), Scholte, L.L.S. (Larissa L. S.), Storey, K. (Kenneth B.), Swain, M. (Martin), Tennessen, J.A. (Jacob A.), Tomlinson, C. (Chad), Trujillo, D.L. (Damian L.), Volpi, E.V. (Emanuela V.), Walker, A.J. (Anthony J.), Wang, T. (Tianfang), Wannaporn, I. (Ittiprasert), Warren, W.C. (Wesley C.), Wu, X.-J. (Xiao-Jun), Yoshino, T.P. (Timothy P.), Yusuf, M. (Mohammed), Zhang, S.-M. (Si-Ming), Zhao, M. (Min), Wilson, R.K. (Richard K.), Adema, C.M. (Coen M.), Hillier, L.W. (LaDeana W.), Jones, C.S. (Catherine S.), Loker, E.S. (Eric S.), Knight, M. (Matty), Minx, P. (Patrick), Oliveira, G. (Guilherme), Raghavan, N. (Nithya), Shedlock, A. (Andrew), Do Amaral, L.R. (Laurence Rodrigues), Arican-Goktas, H.D. (Halime D.), Assis, J.G. (Juliana G.), Baba, E.H. (Elio Hideo), Baron, O.L. (Olga L.), Bayne, C.J. (Christopher J.), Bickham-Wright, U. (Utibe), Biggar, K.K. (Kyle K.), Blouin, M. (Michael), Bonning, B.C. (Bryony C.), Botka, C. (Chris), Bridger, J.M. (Joanna M.), Buckley, K.M. (Katherine M.), Buddenborg, S.K. (Sarah K.), Lima Caldeira, R. (Roberta), Carleton, J. (Julia), Carvalho, O.S. (Omar S.), Castillo, M.G. (Maria G.), Chalmers, I.W. (Iain W.), Christensens, M. (Mikkel), Clifton, S. (Sandra), Cosseau, C. (Celine), Coustau, C. (Christine), Cripps, R.M. (Richard M.), Cuesta-Astroz, Y. (Yesid), Cummins, S.F. (Scott F.), DI Stephano, L. (Leon), DInguirard, N. (Nathalie), Duval, D. (David), Emrich, S. (Scott), Feschotte, C. (Cédric), Feyereisen, R. (Rene), Fitzgerald, P. (Peter), Fronick, C. (Catrina), Fulton, L. (Lucinda), Galinier, R. (Richard), Gava, S.G. (Sandra G.), Geusz, M. (Michael), Geyer, K.K. (Kathrin K.), Giraldo-Calderón, G.I. (Gloria I.), De Souza Gomes, M. (Matheus), Gordy, M.A. (Michelle A.), Gourbal, B. (Benjamin), Grunau, C. (Christoph), Hanington, P.C. (Patrick C.), Hoffmann, K.F. (Karl F.), Hughes, D. (Daniel), Humphries, J. (Judith), Jackson, D.J. (Daniel J.), Jannotti-Passos, L.K. (Liana K.), De Jesus Jeremias, W. (Wander), Jobling, S. (Susan), Kamel, B. (Bishoy), Kapusta, A. (Aurélie), Kaur, S. (Satwant), Koene, J.M. (Joris M.), Kohn, A.B. (Andrea B.), Lawson, D. (Dan), Lawton, S.P. (Scott P), Liang, D. (Di), Limpanont, Y. (Yanin), Liu, S. (Sijun), Lockyer, A.E. (Anne E.), Lovato, T.L. (TyAnna L.), Ludolf, F. (Fernanda), Magrini, V. (Vince), McManus, D.P. (Donald P.), Medina, M. (Monica), Misra, M. (Milind), Mitta, G. (Guillaume), Mkoji, G.M. (Gerald M.), Montague, M.J. (Michael J.), Montelongo, C. (Cesar), Moroz, L.L. (Leonid L.), Munoz-Torres, M.C. (Monica C.), Niazi, U. (Umar), Noble, L.R. (Leslie R.), Oliveira, F.S. (Francislon S.), Pais, F.S. (Fabiano S.), Papenfuss, A.T. (Anthony T.), Peace, R. (Rob), Pena, J.J. (Janeth J.), Pila, E.A. (Emmanuel A.), Quelais, T. (Titouan), Raney, B.J. (Brian J.), Rast, J.P. (Jonathan P.), Rollinson, D. (David), Rosse, I.C. (Izinara C.), Rotgans, B. (Bronwyn), Routledge, E.J. (Edwin J.), Ryan, K.M. (Kathryn M.), Scholte, L.L.S. (Larissa L. S.), Storey, K. (Kenneth B.), Swain, M. (Martin), Tennessen, J.A. (Jacob A.), Tomlinson, C. (Chad), Trujillo, D.L. (Damian L.), Volpi, E.V. (Emanuela V.), Walker, A.J. (Anthony J.), Wang, T. (Tianfang), Wannaporn, I. (Ittiprasert), Warren, W.C. (Wesley C.), Wu, X.-J. (Xiao-Jun), Yoshino, T.P. (Timothy P.), Yusuf, M. (Mohammed), Zhang, S.-M. (Si-Ming), Zhao, M. (Min), and Wilson, R.K. (Richard K.)
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017
Full Text: View/download PDF

27. Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Author: Adema, Coen M, Adema, Coen M, Hillier, LaDeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F, di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel, Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L, Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T, Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J, Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, Ryan, Kathryn M, Adema, Coen M, Adema, Coen M, Hillier, LaDeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F, di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel, Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L, Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T, Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J, Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, and Ryan, Kathryn M
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017

28. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Author: Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, Wilson, Richard K., Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, and Wilson, Richard K.
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017
Full Text: View/download PDF

29. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Author: Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, Wilson, Richard K., Adema, Coen M., Hillier, Ladeana W., Jones, Catherine S., Loker, Eric S., Knight, Matty, Minx, Patrick, Oliveira, Guilherme, Raghavan, Nithya, Shedlock, Andrew, Do Amaral, Laurence Rodrigues, Arican-goktas, Halime D., Assis, Juliana G., Baba, Elio Hideo, Baron, Olga L., Bayne, Christopher J., Bickham-wright, Utibe, Biggar, Kyle K., Blouin, Michael, Bonning, Bryony C., Botka, Chris, Bridger, Joanna M., Buckley, Katherine M., Buddenborg, Sarah K., Caldeira, Roberta Lima, Carleton, Julia, Carvalho, Omar S., Castillo, Maria G., Chalmers, Iain W., Christensens, Mikkel, Clifton, Sandra, Cosseau, Celine, Coustau, Christine, Cripps, Richard M., Cuesta-astroz, Yesid, Cummins, Scott F., Di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cedric, Feyereisen, Rene, Fitzgerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G., Geusz, Michael, Geyer, Kathrin K., Giraldo-calderon, Gloria I., Gomes, Matheus De Souza, Gordy, Michelle A., Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C., Hoffmann, Karl F., Hughes, Daniel, Humphries, Judith, Jackson, Daniel J., Jannotti-passos, Liana K., Jeremias, Wander De Jesus, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurelie, Kaur, Satwant, Koene, Joris M., Kohn, Andrea B., Lawson, Dan, Lawton, Scott P., Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E., Lovato, Tyanna L., Ludolf, Fernanda, Magrini, Vince, Mcmanus, Donald P., Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M., Montague, Michael J., Montelongo, Cesar, Moroz, Leonid L., Munoz-torres, Monica C., Niazi, Umar, Noble, Leslie R., Oliveira, Francislon S., Pais, Fabiano S., Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J., Pila, Emmanuel A., Quelais, Titouan, Raney, Brian J., Rast, Jonathan P., Rollinson, David, Rosse, Izinara C., Rotgans, Bronwyn, Routledge, Edwin J., Ryan, Kathryn M., Scholte, Larissa L. S., Storey, Kenneth B., Swain, Martin, Tennessen, Jacob A., Tomlinson, Chad, Trujillo, Damian L., Volpi, Emanuela V., Walker, Anthony J., Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-jun, Yoshino, Timothy P., Yusuf, Mohammed, Zhang, Si-ming, Zhao, Min, and Wilson, Richard K.
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017
Full Text: View/download PDF

30. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Author: Adema, Coen M, Hillier, Ladeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme de, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra W, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F., di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel S.T., Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L., Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J., Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, Ryan, Kathryn M, Scholte, Larissa L S, Storey, Kenneth B, Swain, Martin, Tennessen, Jacob A, Tomlinson, Chad, Trujillo, Damian L, Volpi, Emanuela V, Walker, Anthony J, Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-Jun, Yoshino, Timothy P, Junaid Yusuf, Mohammed, Zhang, Si-Ming, Zhao, Min, Wilson, Richard K., Adema, Coen M, Hillier, Ladeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme de, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra W, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F., di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel S.T., Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L., Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J., Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, Ryan, Kathryn M, Scholte, Larissa L S, Storey, Kenneth B, Swain, Martin, Tennessen, Jacob A, Tomlinson, Chad, Trujillo, Damian L, Volpi, Emanuela V, Walker, Anthony J, Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-Jun, Yoshino, Timothy P, Junaid Yusuf, Mohammed, Zhang, Si-Ming, Zhao, Min, and Wilson, Richard K.
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017

31. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

Author: Adema, Coen M, Hillier, Ladeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme de, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra W, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F., di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel S.T., Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L., Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J., Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, Ryan, Kathryn M, Scholte, Larissa L S, Storey, Kenneth B, Swain, Martin, Tennessen, Jacob A, Tomlinson, Chad, Trujillo, Damian L, Volpi, Emanuela V, Walker, Anthony J, Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-Jun, Yoshino, Timothy P, Junaid Yusuf, Mohammed, Zhang, Si-Ming, Zhao, Min, Wilson, Richard K., Adema, Coen M, Hillier, Ladeana W, Jones, Catherine S, Loker, Eric S, Knight, Matty, Minx, Patrick, Oliveira, Guilherme de, Raghavan, Nithya, Shedlock, Andrew, do Amaral, Laurence Rodrigues, Arican-Goktas, Halime D, Assis, Juliana G, Baba, Elio Hideo, Baron, Olga L, Bayne, Christopher J, Bickham-Wright, Utibe, Biggar, Kyle K, Blouin, Michael, Bonning, Bryony C, Botka, Chris, Bridger, Joanna M, Buckley, Katherine M, Buddenborg, Sarah K, Lima Caldeira, Roberta, Carleton, Julia, Carvalho, Omar S, Castillo, Maria G, Chalmers, Iain W, Christensens, Mikkel, Clifton, Sandra W, Cosseau, Celine, Coustau, Christine, Cripps, Richard M, Cuesta-Astroz, Yesid, Cummins, Scott F., di Stephano, Leon, Dinguirard, Nathalie, Duval, David, Emrich, Scott, Feschotte, Cédric, Feyereisen, Rene, FitzGerald, Peter, Fronick, Catrina, Fulton, Lucinda, Galinier, Richard, Gava, Sandra G, Geusz, Michael, Geyer, Kathrin K, Giraldo-Calderón, Gloria I, de Souza Gomes, Matheus, Gordy, Michelle A, Gourbal, Benjamin, Grunau, Christoph, Hanington, Patrick C, Hoffmann, Karl F, Hughes, Daniel S.T., Humphries, Judith, Jackson, Daniel J, Jannotti-Passos, Liana K, de Jesus Jeremias, Wander, Jobling, Susan, Kamel, Bishoy, Kapusta, Aurélie, Kaur, Satwant, Koene, Joris M, Kohn, Andrea B, Lawson, Dan, Lawton, Scott P, Liang, Di, Limpanont, Yanin, Liu, Sijun, Lockyer, Anne E, Lovato, TyAnna L, Ludolf, Fernanda, Magrini, Vince, McManus, Donald P, Medina, Monica, Misra, Milind, Mitta, Guillaume, Mkoji, Gerald M, Montague, Michael J, Montelongo, Cesar, Moroz, Leonid L., Munoz-Torres, Monica C, Niazi, Umar, Noble, Leslie R, Oliveira, Francislon S, Pais, Fabiano S, Papenfuss, Anthony T., Peace, Rob, Pena, Janeth J, Pila, Emmanuel A, Quelais, Titouan, Raney, Brian J., Rast, Jonathan P, Rollinson, David, Rosse, Izinara C, Rotgans, Bronwyn, Routledge, Edwin J, Ryan, Kathryn M, Scholte, Larissa L S, Storey, Kenneth B, Swain, Martin, Tennessen, Jacob A, Tomlinson, Chad, Trujillo, Damian L, Volpi, Emanuela V, Walker, Anthony J, Wang, Tianfang, Wannaporn, Ittiprasert, Warren, Wesley C., Wu, Xiao-Jun, Yoshino, Timothy P, Junaid Yusuf, Mohammed, Zhang, Si-Ming, Zhao, Min, and Wilson, Richard K.
Abstract: Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Published: 2017

32. Modelagem e simulação da secagem solar do pedúnculo de caju

Author: Machado, Antonio Vitor, Oliveira, Edson Leandro de, Araújo de Oliveira, Jackson, Fabiano S. Souza, Domingos, Moura de Freitas, Laerte, Machado, Antonio Vitor, Oliveira, Edson Leandro de, Araújo de Oliveira, Jackson, Fabiano S. Souza, Domingos, and Moura de Freitas, Laerte
Abstract: The high indices of pollution reached by the energy use fossils are sufficiently preoccupying in the present. Actually, the development of new technologies that can use renewable energy sources is quite important. Solar drying of cashew pulp is a viable alternative to take care of to the producers that with the use of this technology will be able to add value for theirs products and to minimize its losses postharvest. In this direction this work had as objective the study of the solar drying of cashew pulp using solar dryer of indirect radiation. Experiments in a unit had been carried through pilot of solar dryer under forced convection, using slices of the cashew pulp with thicknesses of 1cm. Later, a fenomenológico mathematical model was developed to simulate the solar dryer and to analyze the behavior of this front to the pertinent variable of the process. The final model is represented by a system of partial distinguishing equations the two phases (first solid and phase gás) and integrated numerically for the method of the lines. The results gotten with the simulation had been validated with the experiments and, the same ones had revealed condizentes with the data solar drying of cashew pulp., Os altos índices de poluição alcançados pelo uso de energia fosseis é bastante preocupante na atualidade, com isso a busca pela utilização de fontes de energia limpa e renovável é de grande interesse no presente. A secagem solar do pedúnculo de caju é uma alternativa viável para atender aos produtores, que com a utilização desta tecnologia poderão agregar valor aos seus produtos e minimizar suas perdas pós-colheita. Neste sentido este trabalho teve como objetivo o estudo da secagem solar do pedúnculo do caju utilizando um secador solar de radiação indireta. Foram realizados experimentos em uma unidade piloto de secador solar sob convecção forçada, utilizando fatias do pedúnculo de caju com espessuras de 1cm. Posteriormente, foi desenvolvido um modelo matemático fenomenológico para simular o secador solar e analisar o comportamento deste frente às variáveis pertinentes do processo. O modelo final é representado por um sistema de equações diferenciais parciais a duas fases (matriz sólida e fase gás) e integrado numericamente pelo método das linhas. Os resultados obtidos com a simulação foram validados com os experimentos e, os mesmos mostraram-se condizentes com os dados de secagem solar do pedúnculo de caju.
Published: 2012

33. Modelagem e simulação da secagem solar do pedúnculo de caju

Author: Machado, Antonio Vitor, Oliveira, Edson Leandro de, Araújo de Oliveira, Jackson, Fabiano S. Souza, Domingos, Moura de Freitas, Laerte, Machado, Antonio Vitor, Oliveira, Edson Leandro de, Araújo de Oliveira, Jackson, Fabiano S. Souza, Domingos, and Moura de Freitas, Laerte
Abstract: The high indices of pollution reached by the energy use fossils are sufficiently preoccupying in the present. Actually, the development of new technologies that can use renewable energy sources is quite important. Solar drying of cashew pulp is a viable alternative to take care of to the producers that with the use of this technology will be able to add value for theirs products and to minimize its losses postharvest. In this direction this work had as objective the study of the solar drying of cashew pulp using solar dryer of indirect radiation. Experiments in a unit had been carried through pilot of solar dryer under forced convection, using slices of the cashew pulp with thicknesses of 1cm. Later, a fenomenológico mathematical model was developed to simulate the solar dryer and to analyze the behavior of this front to the pertinent variable of the process. The final model is represented by a system of partial distinguishing equations the two phases (first solid and phase gás) and integrated numerically for the method of the lines. The results gotten with the simulation had been validated with the experiments and, the same ones had revealed condizentes with the data solar drying of cashew pulp., Os altos índices de poluição alcançados pelo uso de energia fosseis é bastante preocupante na atualidade, com isso a busca pela utilização de fontes de energia limpa e renovável é de grande interesse no presente. A secagem solar do pedúnculo de caju é uma alternativa viável para atender aos produtores, que com a utilização desta tecnologia poderão agregar valor aos seus produtos e minimizar suas perdas pós-colheita. Neste sentido este trabalho teve como objetivo o estudo da secagem solar do pedúnculo do caju utilizando um secador solar de radiação indireta. Foram realizados experimentos em uma unidade piloto de secador solar sob convecção forçada, utilizando fatias do pedúnculo de caju com espessuras de 1cm. Posteriormente, foi desenvolvido um modelo matemático fenomenológico para simular o secador solar e analisar o comportamento deste frente às variáveis pertinentes do processo. O modelo final é representado por um sistema de equações diferenciais parciais a duas fases (matriz sólida e fase gás) e integrado numericamente pelo método das linhas. Os resultados obtidos com a simulação foram validados com os experimentos e, os mesmos mostraram-se condizentes com os dados de secagem solar do pedúnculo de caju.
Published: 2012

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33 results on '"Fabiano, S"'

1. Bismuth-based perovskite-derivateswith thermal voltage exceeding 40mV/K

2. Bismuth-Based Perovskite Derivates with Thermal Voltage Exceeding 40 mV/K

3. Bi-based perovskite-derivates with significant Seebeck coefficients

4. Thinness and its variations on some graph families and coloring graphs of bounded thinness

5. Maximum Cut on Interval Graphs of Interval Count Four Is NP-Complete

6. Sequential Doping of Ladder-Type Conjugated Polymers for Thermally Stable n-Type Organic Conductors

7. Sequential Doping of Ladder-Type Conjugated Polymers for Thermally Stable n-Type Organic Conductors

8. Precise tuning of interlayer electronic coupling in layered conductive metal-organic frameworks

9. Natural Product Betulin-Based Insulating Polymer Filler in Organic Solar Cells

10. Precise tuning of interlayer electronic coupling in layered conductive metal-organic frameworks

11. Edge Intersection Graphs of Paths on a Triangular Grid

12. MaxCut on Permutation Graphs is NP-complete

13. Maximum Cut on Interval Graphs of Interval Count Four Is NP-Complete

14. Optimal allocation of proton therapy slots in combined proton-photon radiotherapy

15. Optimal allocation of proton therapy slots in combined proton-photon radiotherapy

16. Thinness of product graphs

17. Precedence thinness in graphs

18. Linear-time Algorithms for Eliminating Claws in Graphs

19. Maximum cut on interval graphs of interval count four is NP-complete

20. Combined proton-photon treatments: How can limited proton slots be optimally distributed over a patient cohort?

21. Combined proton-photon treatments: How can limited proton slots be optimally distributed over a patient cohort?

22. Effectiveness of First-Line Bevacizumab in Metastatic Colorectal Cancer: The Observational Cohort Study GRETA

23. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

24. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

25. Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

26. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

27. Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

28. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

29. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

30. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

31. Whole genome analysis of a schistosomiasis-transmitting freshwater snail

32. Modelagem e simulação da secagem solar do pedúnculo de caju

33. Modelagem e simulação da secagem solar do pedúnculo de caju

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33 results on '"Fabiano, S"'

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