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Your search keyword '"Blussé van Oud Alblas A"' showing total 11 results
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11 results on '"Blussé van Oud Alblas A"'

1. The association of polypharmacy with functional decline in elderly patients undergoing cardiac surgery

Author

Onderzoek, Arends, Britta C, Blussé van Oud-Alblas, Heleen J, Vernooij, Lisette M, Verwijmeren, Lisa, Biesma, Douwe H, Knibbe, Catherijne A J, Noordzij, Peter G, van Dongen, Eric P A, Onderzoek, Arends, Britta C, Blussé van Oud-Alblas, Heleen J, Vernooij, Lisette M, Verwijmeren, Lisa, Biesma, Douwe H, Knibbe, Catherijne A J, Noordzij, Peter G, and van Dongen, Eric P A

Published
2022

2. A bodyweight-dependent allometric exponent for scaling clearance across the human life-span

Author

Wang, C. (Chenguang), Peeters, M.Y. (Mariska), Allegaert, K.M. (Karel), Blussé van Oud-Alblas, H.J. (Heleen), Krekels, E.H.J. (Elke), Tibboel, D. (Dick), Danhof, M. (Meindert), Knibbe, C.A.J. (Catherijne), Wang, C. (Chenguang), Peeters, M.Y. (Mariska), Allegaert, K.M. (Karel), Blussé van Oud-Alblas, H.J. (Heleen), Krekels, E.H.J. (Elke), Tibboel, D. (Dick), Danhof, M. (Meindert), and Knibbe, C.A.J. (Catherijne)

Abstract

Purpose: To explore different allometric equations for scaling clearance across the human life-span using propofol as a model drug. Methods: Data from seven previously published propofol studies ((pre)term neonates, infants, toddlers, children, adolescents and adults) were analysed using NONMEM VI. To scale clearance, a bodyweight-based exponential equation with four different structures for the exponent was used: (I) 3/4 allometric scaling model; (II) mixture model; (III) bodyweight-cut-point separated model; (IV) bodyweight-dependent exponent model. Results: Model I adequately described clearance in adults and older children, but overestimated clearance of neonates and underestimated clearance of infants. Use of two different exponents in Model II and Model III showed significantly improved performance, but yielded ambiguities on the boundaries of the two subpopulations. This discontinuity was overcome in Model IV, in which the exponent changed sigmoidally from 1.35 at a hypothetical bodyweight of 0 kg to a value of 0.56 from 10 kg onwards, thereby describing clearance of all individuals best. Conclusions: A model was developed for scaling clearance over the entire human life-span with a single continuous equation, in which the exponent of the bodyweight-based exponential equation varied with bodyweight.

Published
2012
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6. Characteristics of human monocytes cultured in the Teflon culture bag

Author

Meer, J.W.M. van der, Gevel, J.S. van de, Blussé van Oud Alblas, A., Kramps, J.A., Zwet, Th.L. van, Leijh, P.C.J., Furth, R. van, Meer, J.W.M. van der, Gevel, J.S. van de, Blussé van Oud Alblas, A., Kramps, J.A., Zwet, Th.L. van, Leijh, P.C.J., and Furth, R. van

Abstract

Contains fulltext : 4336.pdf (publisher's version ) (Open Access)

Published
1982

8. Characteristics of human monocytes cultured in the Teflon culture bag

Author

Meer, J.W.M. van der, Gevel, J.S. van de, Blussé van Oud Alblas, A., Kramps, J.A., Zwet, Th.L. van, Leijh, P.C.J., Furth, R. van, Meer, J.W.M. van der, Gevel, J.S. van de, Blussé van Oud Alblas, A., Kramps, J.A., Zwet, Th.L. van, Leijh, P.C.J., and Furth, R. van

Abstract

Contains fulltext : 4336.pdf (publisher's version ) (Open Access)

Published
1982

9. Characteristics of human monocytes cultured in the Teflon culture bag

Author

Meer, J.W.M. van der, Gevel, J.S. van de, Blussé van Oud Alblas, A., Kramps, J.A., Zwet, Th.L. van, Leijh, P.C.J., Furth, R. van, Meer, J.W.M. van der, Gevel, J.S. van de, Blussé van Oud Alblas, A., Kramps, J.A., Zwet, Th.L. van, Leijh, P.C.J., and Furth, R. van

Abstract

Contains fulltext : 4336.pdf (publisher's version ) (Open Access)

Published
1982

10. Cantiques pour le culte public

Author

Waalse Kerken (Nederland), Blussé van Oud-Alblas, Adolph 1779-1846 impresor, Waalse Kerken (Nederland), and Blussé van Oud-Alblas, Adolph 1779-1846 impresor

Abstract

Anglés y Subirá, Sign.: A-K¹²

11. Cantiques pour le culte public

Author

Waalse Kerken (Nederland), Blussé van Oud-Alblas, Adolph 1779-1846 impresor, Waalse Kerken (Nederland), and Blussé van Oud-Alblas, Adolph 1779-1846 impresor

Abstract

Anglés y Subirá, Sign.: A-K¹²

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