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The electrification and digitalization of our society has propelled the demand for energy storage solutions. High-end technologies have been developed to satisfy the requirements of demanding applications, such as electromobility and portable consumer electronics, which also increasingly find markets for less demanding applications. These markets include grid and domestic energy storage, as well as Internet of Things (IoT). However, using high-end technologies for low-end applications is a waste of resources that puts unnecessary stress on the supply lines. Thus, more low-cost cost and environmentally friendly alternative technologies are sought, among which renewable biobased materials derived from agriculture and forestry play a prominent role. The dominant chemical constituents in plants, cellulose and lignin, exhibit some intriguing electrochemical and colloidal properties. Cellulose has been found to efficiently stabilize various electronic materials, whereas lignin can be used as an electronic material itself. Lignocellulosic materials also open for papermaking as an alternative manufacturing approach. Taking the step to using papermaking methods is, however, a bit far from the technology readiness level, as the vast majority of the research on paper electrodes is based on nanocellulose. The material properties of such nanopapers are indeed extraordinary, but the lack of large-scale production methods for nanopapers is a serious challenge. To circumvent this obstacle and find a shortcut to the realization of paper electrodes, this thesis has turned to conventional papermaking techniques. Fibres are essentially different to nanofibrils by their difference in size, and the papermaking process requires careful composition of the formulations. Thus, as the research on nanopaper electrodes cannot be directly translated into conventional papermaking techniques, this calls for separate studies on fibre-based systems. This thesis is based on four separate works carrie

The electrification and digitalization of our society has propelled the demand for energy storage solutions. High-end technologies have been developed to satisfy the requirements of demanding applications, such as electromobility and portable consumer electronics, which also increasingly find markets for less demanding applications. These markets include grid and domestic energy storage, as well as Internet of Things (IoT). However, using high-end technologies for low-end applications is a waste of resources that puts unnecessary stress on the supply lines. Thus, more low-cost cost and environmentally friendly alternative technologies are sought, among which renewable biobased materials derived from agriculture and forestry play a prominent role. The dominant chemical constituents in plants, cellulose and lignin, exhibit some intriguing electrochemical and colloidal properties. Cellulose has been found to efficiently stabilize various electronic materials, whereas lignin can be used as an electronic material itself. Lignocellulosic materials also open for papermaking as an alternative manufacturing approach. Taking the step to using papermaking methods is, however, a bit far from the technology readiness level, as the vast majority of the research on paper electrodes is based on nanocellulose. The material properties of such nanopapers are indeed extraordinary, but the lack of large-scale production methods for nanopapers is a serious challenge. To circumvent this obstacle and find a shortcut to the realization of paper electrodes, this thesis has turned to conventional papermaking techniques. Fibres are essentially different to nanofibrils by their difference in size, and the papermaking process requires careful composition of the formulations. Thus, as the research on nanopaper electrodes cannot be directly translated into conventional papermaking techniques, this calls for separate studies on fibre-based systems. This thesis is based on four separate works carrie

The electrification and digitalization of our society has propelled the demand for energy storage solutions. High-end technologies have been developed to satisfy the requirements of demanding applications, such as electromobility and portable consumer electronics, which also increasingly find markets for less demanding applications. These markets include grid and domestic energy storage, as well as Internet of Things (IoT). However, using high-end technologies for low-end applications is a waste of resources that puts unnecessary stress on the supply lines. Thus, more low-cost cost and environmentally friendly alternative technologies are sought, among which renewable biobased materials derived from agriculture and forestry play a prominent role. The dominant chemical constituents in plants, cellulose and lignin, exhibit some intriguing electrochemical and colloidal properties. Cellulose has been found to efficiently stabilize various electronic materials, whereas lignin can be used as an electronic material itself. Lignocellulosic materials also open for papermaking as an alternative manufacturing approach. Taking the step to using papermaking methods is, however, a bit far from the technology readiness level, as the vast majority of the research on paper electrodes is based on nanocellulose. The material properties of such nanopapers are indeed extraordinary, but the lack of large-scale production methods for nanopapers is a serious challenge. To circumvent this obstacle and find a shortcut to the realization of paper electrodes, this thesis has turned to conventional papermaking techniques. Fibres are essentially different to nanofibrils by their difference in size, and the papermaking process requires careful composition of the formulations. Thus, as the research on nanopaper electrodes cannot be directly translated into conventional papermaking techniques, this calls for separate studies on fibre-based systems. This thesis is based on four separate works carrie

The electrification and digitalization of our society has propelled the demand for energy storage solutions. High-end technologies have been developed to satisfy the requirements of demanding applications, such as electromobility and portable consumer electronics, which also increasingly find markets for less demanding applications. These markets include grid and domestic energy storage, as well as Internet of Things (IoT). However, using high-end technologies for low-end applications is a waste of resources that puts unnecessary stress on the supply lines. Thus, more low-cost cost and environmentally friendly alternative technologies are sought, among which renewable biobased materials derived from agriculture and forestry play a prominent role. The dominant chemical constituents in plants, cellulose and lignin, exhibit some intriguing electrochemical and colloidal properties. Cellulose has been found to efficiently stabilize various electronic materials, whereas lignin can be used as an electronic material itself. Lignocellulosic materials also open for papermaking as an alternative manufacturing approach. Taking the step to using papermaking methods is, however, a bit far from the technology readiness level, as the vast majority of the research on paper electrodes is based on nanocellulose. The material properties of such nanopapers are indeed extraordinary, but the lack of large-scale production methods for nanopapers is a serious challenge. To circumvent this obstacle and find a shortcut to the realization of paper electrodes, this thesis has turned to conventional papermaking techniques. Fibres are essentially different to nanofibrils by their difference in size, and the papermaking process requires careful composition of the formulations. Thus, as the research on nanopaper electrodes cannot be directly translated into conventional papermaking techniques, this calls for separate studies on fibre-based systems. This thesis is based on four separate works carrie

This special section is composed of substantially extended handpicked papers from the IEEE Nordic Circuits and Systems Conference (NorCAS) 2022 that took place in October 2022 in Oslo, Norway.

Printed electronic paper identifies its interest in flexible organic electronics and sustainable and clean energy applications because of its straightforward production method, cost-effectiveness, and positive environmental impact. However, current limitations include restricted material thickness and the use of supporting substrate for printing. Here, 2D and 3D electronic patterned paper are fabricated from direct ink writing (DIW) nanocellulose and PEDOT:PSS-based materials using syringe deposition and 3D printing. The conductor patterns are integrated in the bulk of the paper, while non-conductive sections are used as support to form free-standing paper. The strong interface between the patterns of electronic patterned paper gives mechanical stability for practical handling. The conductive paper-based electrode has 202 S cm(-1) and is capable of handling electric current up to 0.7 A, which can be used for high-power devices. Printed supercapacitor papers show high specific energy of 4.05 Wh kg(-1), specific power of 4615 W kg(-1) at 0.06 A g(-1), and capacitance retention above 95% after 2000 cycles. The new design structure of electronic patterned papers presents a solution for additive manufacturing of paper-based composites for supercapacitors, wearable electronics, or sensors for smart packaging.

The rise of paper electronics has been accelerated due to the public push for sustainability. Electronic waste can potentially be avoided if certain materials in electronic components can be substituted for greener alternatives such as paper. Within this report, it is demonstrated that conductive polymers poly(3,4-ethylenedoxythiophene) (PEDOT), polypyrrole, and polythiophene, can be synthesized by screen printing combined with vapor phase polymerization on paper substrates and further incorporated into functional electronic components. High patterning resolution (100 mu m) is achieved for all conductive polymers, with PEDOT showing impressive sheet resistance values. PEDOT is incorporated as conductive circuitry and as the active material in all-printed electrochromic displays. The conductive polymer circuits allow for functional light emitting diodes, while the electrochromic displays are comparable to commercial displays utilizing PEDOT on plastic substrates., Funding Agencies|Swedish Foundation for Strategic Research [EM16-0002]; Vinnova for the Digital Cellulose Center [2016-05193]; European Union [101008701]

Printed electronic paper identifies its interest in flexible organic electronics and sustainable and clean energy applications because of its straightforward production method, cost-effectiveness, and positive environmental impact. However, current limitations include restricted material thickness and the use of supporting substrate for printing. Here, 2D and 3D electronic patterned paper are fabricated from direct ink writing (DIW) nanocellulose and PEDOT:PSS-based materials using syringe deposition and 3D printing. The conductor patterns are integrated in the bulk of the paper, while non-conductive sections are used as support to form free-standing paper. The strong interface between the patterns of electronic patterned paper gives mechanical stability for practical handling. The conductive paper-based electrode has 202 S cm(-1) and is capable of handling electric current up to 0.7 A, which can be used for high-power devices. Printed supercapacitor papers show high specific energy of 4.05 Wh kg(-1), specific power of 4615 W kg(-1) at 0.06 A g(-1), and capacitance retention above 95% after 2000 cycles. The new design structure of electronic patterned papers presents a solution for additive manufacturing of paper-based composites for supercapacitors, wearable electronics, or sensors for smart packaging.

The rise of paper electronics has been accelerated due to the public push for sustainability. Electronic waste can potentially be avoided if certain materials in electronic components can be substituted for greener alternatives such as paper. Within this report, it is demonstrated that conductive polymers poly(3,4-ethylenedoxythiophene) (PEDOT), polypyrrole, and polythiophene, can be synthesized by screen printing combined with vapor phase polymerization on paper substrates and further incorporated into functional electronic components. High patterning resolution (100 mu m) is achieved for all conductive polymers, with PEDOT showing impressive sheet resistance values. PEDOT is incorporated as conductive circuitry and as the active material in all-printed electrochromic displays. The conductive polymer circuits allow for functional light emitting diodes, while the electrochromic displays are comparable to commercial displays utilizing PEDOT on plastic substrates., Funding Agencies|Swedish Foundation for Strategic Research [EM16-0002]; Vinnova for the Digital Cellulose Center [2016-05193]; European Union [101008701]

Printed electronic paper identifies its interest in flexible organic electronics and sustainable and clean energy applications because of its straightforward production method, cost-effectiveness, and positive environmental impact. However, current limitations include restricted material thickness and the use of supporting substrate for printing. Here, 2D and 3D electronic patterned paper are fabricated from direct ink writing (DIW) nanocellulose and PEDOT:PSS-based materials using syringe deposition and 3D printing. The conductor patterns are integrated in the bulk of the paper, while non-conductive sections are used as support to form free-standing paper. The strong interface between the patterns of electronic patterned paper gives mechanical stability for practical handling. The conductive paper-based electrode has 202 S cm(-1) and is capable of handling electric current up to 0.7 A, which can be used for high-power devices. Printed supercapacitor papers show high specific energy of 4.05 Wh kg(-1), specific power of 4615 W kg(-1) at 0.06 A g(-1), and capacitance retention above 95% after 2000 cycles. The new design structure of electronic patterned papers presents a solution for additive manufacturing of paper-based composites for supercapacitors, wearable electronics, or sensors for smart packaging.

The rise of paper electronics has been accelerated due to the public push for sustainability. Electronic waste can potentially be avoided if certain materials in electronic components can be substituted for greener alternatives such as paper. Within this report, it is demonstrated that conductive polymers poly(3,4-ethylenedoxythiophene) (PEDOT), polypyrrole, and polythiophene, can be synthesized by screen printing combined with vapor phase polymerization on paper substrates and further incorporated into functional electronic components. High patterning resolution (100 mu m) is achieved for all conductive polymers, with PEDOT showing impressive sheet resistance values. PEDOT is incorporated as conductive circuitry and as the active material in all-printed electrochromic displays. The conductive polymer circuits allow for functional light emitting diodes, while the electrochromic displays are comparable to commercial displays utilizing PEDOT on plastic substrates., Funding Agencies|Swedish Foundation for Strategic Research [EM16-0002]; Vinnova for the Digital Cellulose Center [2016-05193]; European Union [101008701]

Printed electronic paper identifies its interest in flexible organic electronics and sustainable and clean energy applications because of its straightforward production method, cost-effectiveness, and positive environmental impact. However, current limitations include restricted material thickness and the use of supporting substrate for printing. Here, 2D and 3D electronic patterned paper are fabricated from direct ink writing (DIW) nanocellulose and PEDOT:PSS-based materials using syringe deposition and 3D printing. The conductor patterns are integrated in the bulk of the paper, while non-conductive sections are used as support to form free-standing paper. The strong interface between the patterns of electronic patterned paper gives mechanical stability for practical handling. The conductive paper-based electrode has 202 S cm(-1) and is capable of handling electric current up to 0.7 A, which can be used for high-power devices. Printed supercapacitor papers show high specific energy of 4.05 Wh kg(-1), specific power of 4615 W kg(-1) at 0.06 A g(-1), and capacitance retention above 95% after 2000 cycles. The new design structure of electronic patterned papers presents a solution for additive manufacturing of paper-based composites for supercapacitors, wearable electronics, or sensors for smart packaging.

The rise of paper electronics has been accelerated due to the public push for sustainability. Electronic waste can potentially be avoided if certain materials in electronic components can be substituted for greener alternatives such as paper. Within this report, it is demonstrated that conductive polymers poly(3,4-ethylenedoxythiophene) (PEDOT), polypyrrole, and polythiophene, can be synthesized by screen printing combined with vapor phase polymerization on paper substrates and further incorporated into functional electronic components. High patterning resolution (100 mu m) is achieved for all conductive polymers, with PEDOT showing impressive sheet resistance values. PEDOT is incorporated as conductive circuitry and as the active material in all-printed electrochromic displays. The conductive polymer circuits allow for functional light emitting diodes, while the electrochromic displays are comparable to commercial displays utilizing PEDOT on plastic substrates., Funding Agencies|Swedish Foundation for Strategic Research [EM16-0002]; Vinnova for the Digital Cellulose Center [2016-05193]; European Union [101008701]

The rise of paper electronics has been accelerated due to the public push for sustainability. Electronic waste can potentially be avoided if certain materials in electronic components can be substituted for greener alternatives such as paper. Within this report, it is demonstrated that conductive polymers poly(3,4-ethylenedoxythiophene) (PEDOT), polypyrrole, and polythiophene, can be synthesized by screen printing combined with vapor phase polymerization on paper substrates and further incorporated into functional electronic components. High patterning resolution (100 mu m) is achieved for all conductive polymers, with PEDOT showing impressive sheet resistance values. PEDOT is incorporated as conductive circuitry and as the active material in all-printed electrochromic displays. The conductive polymer circuits allow for functional light emitting diodes, while the electrochromic displays are comparable to commercial displays utilizing PEDOT on plastic substrates., Funding Agencies|Swedish Foundation for Strategic Research [EM16-0002]; Vinnova for the Digital Cellulose Center [2016-05193]; European Union [101008701]

Printed electronic paper identifies its interest in flexible organic electronics and sustainable and clean energy applications because of its straightforward production method, cost-effectiveness, and positive environmental impact. However, current limitations include restricted material thickness and the use of supporting substrate for printing. Here, 2D and 3D electronic patterned paper are fabricated from direct ink writing (DIW) nanocellulose and PEDOT:PSS-based materials using syringe deposition and 3D printing. The conductor patterns are integrated in the bulk of the paper, while non-conductive sections are used as support to form free-standing paper. The strong interface between the patterns of electronic patterned paper gives mechanical stability for practical handling. The conductive paper-based electrode has 202 S cm(-1) and is capable of handling electric current up to 0.7 A, which can be used for high-power devices. Printed supercapacitor papers show high specific energy of 4.05 Wh kg(-1), specific power of 4615 W kg(-1) at 0.06 A g(-1), and capacitance retention above 95% after 2000 cycles. The new design structure of electronic patterned papers presents a solution for additive manufacturing of paper-based composites for supercapacitors, wearable electronics, or sensors for smart packaging.

The transition to a sustainable society is driving the development of green electronic solutions designed to have a minimal environmental impact. One promising route to achieve this goal is to construct electronics from biobased materials like cellulose, which is carbon neutral, non‐toxic, and recyclable. This is especially true for internet‐of‐things devices, which are rapidly growing in number and are becoming embedded in every aspect of our lives. Here, paper‐based sensor circuits are demonstrated, which use triboelectric pressure sensors to help elderly people communicate with the digital world using an interface in the form of an electronic “book”, which is more intuitive to them. The sensors are manufactured by screen printing onto flexible paper substrates, using in‐house developed cellulose‐based inks with non‐hazardous solvents. The triboelectric sensor signal, generated by the contact between a finger and chemically modified cellulose, can reach several volts, which can be registered by a portable microcontroller card and transmitted by Bluetooth to any device with an internet connection. Apart from the microcontroller (which can be easily removed), the whole system can be recycled at the end of life. A triboelectric touch interface, manufactured using printed electronics on flexible paper substrates, using cellulose‐based functional inks is demonstrated. These metal‐free green electronics circuits are implemented in an “electronic book” demonstrator, equipped with wireless communication that can control remote devices, as a step toward sustainable and recyclable internet‐of‐things devices., The authors would like to acknowledge funding from Vinnova through theD igital Cellulose Competence Center (DCC), Diary number 2016–05193, the Swedish Foundation for Strategic Research (Smart Intra-body network; grant RIT15-0119), and the Norrköping municipality fund for research and development (Accessibility and remembering – storytelling and innovative media use in elderly care homes, 2020. Grant: KS 2020/0345). The work was also supported by Treesearch.se. The authors thank Patrik Isacsson and co-workers at Ahlstrom Munksjö for providing the paper substrates and for valuable know-how as part of the collaboration within DCC, as well as Erik Gabrielsson, Daniel Simon, Elisabet Cedersund, and Lars Herlogsson for their involvement in the work on the original Mediabook platform.

The transition to a sustainable society is driving the development of green electronic solutions designed to have a minimal environmental impact. One promising route to achieve this goal is to construct electronics from biobased materials like cellulose, which is carbon neutral, non‐toxic, and recyclable. This is especially true for internet‐of‐things devices, which are rapidly growing in number and are becoming embedded in every aspect of our lives. Here, paper‐based sensor circuits are demonstrated, which use triboelectric pressure sensors to help elderly people communicate with the digital world using an interface in the form of an electronic “book”, which is more intuitive to them. The sensors are manufactured by screen printing onto flexible paper substrates, using in‐house developed cellulose‐based inks with non‐hazardous solvents. The triboelectric sensor signal, generated by the contact between a finger and chemically modified cellulose, can reach several volts, which can be registered by a portable microcontroller card and transmitted by Bluetooth to any device with an internet connection. Apart from the microcontroller (which can be easily removed), the whole system can be recycled at the end of life. A triboelectric touch interface, manufactured using printed electronics on flexible paper substrates, using cellulose‐based functional inks is demonstrated. These metal‐free green electronics circuits are implemented in an “electronic book” demonstrator, equipped with wireless communication that can control remote devices, as a step toward sustainable and recyclable internet‐of‐things devices., The authors would like to acknowledge funding from Vinnova through theD igital Cellulose Competence Center (DCC), Diary number 2016–05193, the Swedish Foundation for Strategic Research (Smart Intra-body network; grant RIT15-0119), and the Norrköping municipality fund for research and development (Accessibility and remembering – storytelling and innovative media use in elderly care homes, 2020. Grant: KS 2020/0345). The work was also supported by Treesearch.se. The authors thank Patrik Isacsson and co-workers at Ahlstrom Munksjö for providing the paper substrates and for valuable know-how as part of the collaboration within DCC, as well as Erik Gabrielsson, Daniel Simon, Elisabet Cedersund, and Lars Herlogsson for their involvement in the work on the original Mediabook platform.

The transition to a sustainable society is driving the development of green electronic solutions designed to have a minimal environmental impact. One promising route to achieve this goal is to construct electronics from biobased materials like cellulose, which is carbon neutral, non‐toxic, and recyclable. This is especially true for internet‐of‐things devices, which are rapidly growing in number and are becoming embedded in every aspect of our lives. Here, paper‐based sensor circuits are demonstrated, which use triboelectric pressure sensors to help elderly people communicate with the digital world using an interface in the form of an electronic “book”, which is more intuitive to them. The sensors are manufactured by screen printing onto flexible paper substrates, using in‐house developed cellulose‐based inks with non‐hazardous solvents. The triboelectric sensor signal, generated by the contact between a finger and chemically modified cellulose, can reach several volts, which can be registered by a portable microcontroller card and transmitted by Bluetooth to any device with an internet connection. Apart from the microcontroller (which can be easily removed), the whole system can be recycled at the end of life. A triboelectric touch interface, manufactured using printed electronics on flexible paper substrates, using cellulose‐based functional inks is demonstrated. These metal‐free green electronics circuits are implemented in an “electronic book” demonstrator, equipped with wireless communication that can control remote devices, as a step toward sustainable and recyclable internet‐of‐things devices., The authors would like to acknowledge funding from Vinnova through theD igital Cellulose Competence Center (DCC), Diary number 2016–05193, the Swedish Foundation for Strategic Research (Smart Intra-body network; grant RIT15-0119), and the Norrköping municipality fund for research and development (Accessibility and remembering – storytelling and innovative media use in elderly care homes, 2020. Grant: KS 2020/0345). The work was also supported by Treesearch.se. The authors thank Patrik Isacsson and co-workers at Ahlstrom Munksjö for providing the paper substrates and for valuable know-how as part of the collaboration within DCC, as well as Erik Gabrielsson, Daniel Simon, Elisabet Cedersund, and Lars Herlogsson for their involvement in the work on the original Mediabook platform.

The transition to a sustainable society is driving the development of green electronic solutions designed to have a minimal environmental impact. One promising route to achieve this goal is to construct electronics from biobased materials like cellulose, which is carbon neutral, non‐toxic, and recyclable. This is especially true for internet‐of‐things devices, which are rapidly growing in number and are becoming embedded in every aspect of our lives. Here, paper‐based sensor circuits are demonstrated, which use triboelectric pressure sensors to help elderly people communicate with the digital world using an interface in the form of an electronic “book”, which is more intuitive to them. The sensors are manufactured by screen printing onto flexible paper substrates, using in‐house developed cellulose‐based inks with non‐hazardous solvents. The triboelectric sensor signal, generated by the contact between a finger and chemically modified cellulose, can reach several volts, which can be registered by a portable microcontroller card and transmitted by Bluetooth to any device with an internet connection. Apart from the microcontroller (which can be easily removed), the whole system can be recycled at the end of life. A triboelectric touch interface, manufactured using printed electronics on flexible paper substrates, using cellulose‐based functional inks is demonstrated. These metal‐free green electronics circuits are implemented in an “electronic book” demonstrator, equipped with wireless communication that can control remote devices, as a step toward sustainable and recyclable internet‐of‐things devices., The authors would like to acknowledge funding from Vinnova through theD igital Cellulose Competence Center (DCC), Diary number 2016–05193, the Swedish Foundation for Strategic Research (Smart Intra-body network; grant RIT15-0119), and the Norrköping municipality fund for research and development (Accessibility and remembering – storytelling and innovative media use in elderly care homes, 2020. Grant: KS 2020/0345). The work was also supported by Treesearch.se. The authors thank Patrik Isacsson and co-workers at Ahlstrom Munksjö for providing the paper substrates and for valuable know-how as part of the collaboration within DCC, as well as Erik Gabrielsson, Daniel Simon, Elisabet Cedersund, and Lars Herlogsson for their involvement in the work on the original Mediabook platform.

This work demonstrates sensitive and low-cost piezoelectric sensors on skin-friendly, ultrathin, and conformable substrates combined with organic electrochemical transistors (OECTs) for the detection and amplification of alternating low-voltage input signals. The fully screen-printed (SP) piezoelectric sensors were manufactured on commercially available tattoo paper substrates, while the all-printed OECTs, relying on an extended gate electrode architecture, were manufactured either by solely using SP or by combining SP and aerosol jet printing (AJP) on PET substrates. Applying a low-voltage signal (+/- 25 mV) to the gate electrode of the SP+AJP OECT results in approximately five times higher current modulation as compared to the fully SP reference OECT. The tattoo paper-based substrate enables transfer of the SP piezoelectric sensor to the skin, which in turn allows for radial pulse monitoring when combined with the SP+AJP OECT; this is possible due to the ability of the conformable sensor to convert mechanical vibrations into voltage signals along with the highly sensitive current modulation ability of the transistor device to further amplify the output signal. The results reported herein pave the way toward all-printed fully conformable wearable devices with high sensitivity to be further utilized for the real-time monitoring of electrophysiological signals., Funding Agencies|HORIZON EUROPE Marie Sklodowska-Curie Actions [825339, 964677]; European Union

The global efforts in electrifying our society drive the demand for low-cost and sustainable energy storage solutions. In the present work, a novel material concept was investigated to enable fabrication of several 10 meter-long rolls of supercapacitor paper electrodes on a pilot-scale paper machine. The material concept was based on cationized, cellulose-rich wood-derived fibres, conducting polymer PEDOT:PSS, and activated carbon filler particles. Cationic fibres saturated with anionic PEDOT:PSS provide a conducting scaffold hosting the activated carbon, which functions as the active charge-storage material. The response from further additives was systematically investigated for several critical paper properties. Cellulose nanofibrils were found to improve mechanical properties, while carbon black enhanced both the conductivity and the storage capacity of the activated carbon, reaching a specific capacitance of 67 F g(-1). This pilot trial shows that "classical" papermaking methods are fit for the purpose and provides valuable insights on how to further advance bio-based energy storage solutions for large-scale applications., Funding Agencies|Swedish Innovation Agency VINNOVA [2016-05193]; Swedish Foundation for Strategic Research [GMT14-0058]

The global efforts in electrifying our society drive the demand for low-cost and sustainable energy storage solutions. In the present work, a novel material concept was investigated to enable fabrication of several 10 meter-long rolls of supercapacitor paper electrodes on a pilot-scale paper machine. The material concept was based on cationized, cellulose-rich wood-derived fibres, conducting polymer PEDOT:PSS, and activated carbon filler particles. Cationic fibres saturated with anionic PEDOT:PSS provide a conducting scaffold hosting the activated carbon, which functions as the active charge-storage material. The response from further additives was systematically investigated for several critical paper properties. Cellulose nanofibrils were found to improve mechanical properties, while carbon black enhanced both the conductivity and the storage capacity of the activated carbon, reaching a specific capacitance of 67 F g(-1). This pilot trial shows that "classical" papermaking methods are fit for the purpose and provides valuable insights on how to further advance bio-based energy storage solutions for large-scale applications., Funding Agencies|Swedish Innovation Agency VINNOVA [2016-05193]; Swedish Foundation for Strategic Research [GMT14-0058]

The global efforts in electrifying our society drive the demand for low-cost and sustainable energy storage solutions. In the present work, a novel material concept was investigated to enable fabrication of several 10 meter-long rolls of supercapacitor paper electrodes on a pilot-scale paper machine. The material concept was based on cationized, cellulose-rich wood-derived fibres, conducting polymer PEDOT:PSS, and activated carbon filler particles. Cationic fibres saturated with anionic PEDOT:PSS provide a conducting scaffold hosting the activated carbon, which functions as the active charge-storage material. The response from further additives was systematically investigated for several critical paper properties. Cellulose nanofibrils were found to improve mechanical properties, while carbon black enhanced both the conductivity and the storage capacity of the activated carbon, reaching a specific capacitance of 67 F g(-1). This pilot trial shows that "classical" papermaking methods are fit for the purpose and provides valuable insights on how to further advance bio-based energy storage solutions for large-scale applications., Funding Agencies|Swedish Innovation Agency VINNOVA [2016-05193]; Swedish Foundation for Strategic Research [GMT14-0058]

The global efforts in electrifying our society drive the demand for low-cost and sustainable energy storage solutions. In the present work, a novel material concept was investigated to enable fabrication of several 10 meter-long rolls of supercapacitor paper electrodes on a pilot-scale paper machine. The material concept was based on cationized, cellulose-rich wood-derived fibres, conducting polymer PEDOT:PSS, and activated carbon filler particles. Cationic fibres saturated with anionic PEDOT:PSS provide a conducting scaffold hosting the activated carbon, which functions as the active charge-storage material. The response from further additives was systematically investigated for several critical paper properties. Cellulose nanofibrils were found to improve mechanical properties, while carbon black enhanced both the conductivity and the storage capacity of the activated carbon, reaching a specific capacitance of 67 F g(-1). This pilot trial shows that "classical" papermaking methods are fit for the purpose and provides valuable insights on how to further advance bio-based energy storage solutions for large-scale applications., Funding Agencies|Swedish Innovation Agency VINNOVA [2016-05193]; Swedish Foundation for Strategic Research [GMT14-0058]

The global efforts in electrifying our society drive the demand for low-cost and sustainable energy storage solutions. In the present work, a novel material concept was investigated to enable fabrication of several 10 meter-long rolls of supercapacitor paper electrodes on a pilot-scale paper machine. The material concept was based on cationized, cellulose-rich wood-derived fibres, conducting polymer PEDOT:PSS, and activated carbon filler particles. Cationic fibres saturated with anionic PEDOT:PSS provide a conducting scaffold hosting the activated carbon, which functions as the active charge-storage material. The response from further additives was systematically investigated for several critical paper properties. Cellulose nanofibrils were found to improve mechanical properties, while carbon black enhanced both the conductivity and the storage capacity of the activated carbon, reaching a specific capacitance of 67 F g(-1). This pilot trial shows that "classical" papermaking methods are fit for the purpose and provides valuable insights on how to further advance bio-based energy storage solutions for large-scale applications., Funding Agencies|Swedish Innovation Agency VINNOVA [2016-05193]; Swedish Foundation for Strategic Research [GMT14-0058]

Kundundersökningar har visat att det undersökta pappersbruket bör förbättra sina leveransledtider. En lösning för detta anses vara en förändring av nuvarande produktionsstrategi. Den nuvarande produktionsstrategin är kundorderproduktion och de alternativa strategierna som kommer att undersökas under studien är lagerorderproduktion och hybridsystem. Syftet med studien är att undersöka, jämföra och analysera olika produktionsstrategier (lagerorderproduktion, kundorderproduktion och hybridsystem) samt att utvärdera deras inverkan på lagerstyrningen. För att uppnå syftet har studien baserats på tre frågeställningar: Vilka för- och nackdelar har produktionsstrategierna på färdigvarulagret samt vilka nyckeltal behöver identifieras? Vilka problem gällande produktion- och lagerstyrning stöter en produktionsplanerare i ett pappersbruk på? Vilken påverkan har produktionsstrategierna på färdigvarulagret hos det undersökta pappersbruket utifrån identifierade nyckeltal. Frågeställningarna besvarades genom att utföra en litteraturstudie om olika produktionsstrategier och lagerstyrning. Med hjälp av litteraturstudien har lämpliga nyckeltal identifierats för att analysera inverkan på lagerstyrning. Utöver litteraturstudien har intervjuer utförts för att skapa en bredare förståelse kring hur det undersökta pappersbruket i helhet ser på produktionsstrategier och dess inverkan på lagerstyrning. Slutligen utfördes en deskriptiv analys för att beräkna de identifierade nyckeltalen. Resultatet från första frågeställningen visade att olika produktionsstrategier kan bidra med olika för- och nackdelar. Dessutom anses en fördel vara en bidragande faktor till en nackdel, exempelvis för hybridsystem kan en förbättring av leveranstider medföra till problem med lagerfyllning. Det är viktigt att även ta hänsyn till hur marknaden ser ut och vilka faktorer som kan påverka samt vad kunderna efterfrågar. Resultatet från andra frågeställningen presenterade tre sammanfattande problem från de utförda int, Examensarbetet är utfört vid Institutionen för teknik och naturvetenskap (ITN) vid Tekniska fakulteten, Linköpings universitet

Kundundersökningar har visat att det undersökta pappersbruket bör förbättra sina leveransledtider. En lösning för detta anses vara en förändring av nuvarande produktionsstrategi. Den nuvarande produktionsstrategin är kundorderproduktion och de alternativa strategierna som kommer att undersökas under studien är lagerorderproduktion och hybridsystem. Syftet med studien är att undersöka, jämföra och analysera olika produktionsstrategier (lagerorderproduktion, kundorderproduktion och hybridsystem) samt att utvärdera deras inverkan på lagerstyrningen. För att uppnå syftet har studien baserats på tre frågeställningar: Vilka för- och nackdelar har produktionsstrategierna på färdigvarulagret samt vilka nyckeltal behöver identifieras? Vilka problem gällande produktion- och lagerstyrning stöter en produktionsplanerare i ett pappersbruk på? Vilken påverkan har produktionsstrategierna på färdigvarulagret hos det undersökta pappersbruket utifrån identifierade nyckeltal. Frågeställningarna besvarades genom att utföra en litteraturstudie om olika produktionsstrategier och lagerstyrning. Med hjälp av litteraturstudien har lämpliga nyckeltal identifierats för att analysera inverkan på lagerstyrning. Utöver litteraturstudien har intervjuer utförts för att skapa en bredare förståelse kring hur det undersökta pappersbruket i helhet ser på produktionsstrategier och dess inverkan på lagerstyrning. Slutligen utfördes en deskriptiv analys för att beräkna de identifierade nyckeltalen. Resultatet från första frågeställningen visade att olika produktionsstrategier kan bidra med olika för- och nackdelar. Dessutom anses en fördel vara en bidragande faktor till en nackdel, exempelvis för hybridsystem kan en förbättring av leveranstider medföra till problem med lagerfyllning. Det är viktigt att även ta hänsyn till hur marknaden ser ut och vilka faktorer som kan påverka samt vad kunderna efterfrågar. Resultatet från andra frågeställningen presenterade tre sammanfattande problem från de utförda int, Examensarbetet är utfört vid Institutionen för teknik och naturvetenskap (ITN) vid Tekniska fakulteten, Linköpings universitet

Recently, an article by Seneff et al. entitled "Innate immunosuppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs" was published in Food and Chemical Toxicology (FCT). Here, we describe why this article, which contains unsubstantiated claims and misunderstandings such as "billions of lives are potentially at risk" with COVID-19 mRNA vaccines, is problematic and should be retracted. We report here our request to the editor of FCT to have our rebuttal published, unfortunately rejected after three rounds of reviewing. Fighting the spread of false information requires enormous effort while receiving little or no credit for this necessary work, which often even ends up being threatened. This need for more scientific integrity is at the heart of our advocacy, and we call for large support, especially from editors and publishers, to fight more effectively against deadly disinformation.

In this work, we demonstrate an effective anion capturing in an aqueous medium using a highly porous carbon paper decorated with ZnO nanorods. A sol-gel technique was first employed to form a thin and compact seed layer of ZnO nanoparticles on the dense network of carbon fibers in the carbon paper. Subsequently, ZnO nanorods were successfully grown on the pre-seeded carbon papers using inexpensive chemical bath deposition. The prepared porous electrodes were electrochemically investigated for improved charge storage and stability under long-term operational conditions. The results show effective capacitive deionization with a maximum areal capacitance of 2 mF/cm(2), an energy consumption of 50 kJ per mole of chlorine ions, and an excellent long-term stability of the fabricated C-ZnO electrodes. The experimental results are supported by COMSOL simulations. Besides the demonstrated capacitive desalination application, our results can directly be used to realize suitable electrodes for energy storage in supercapacitors., Funding Agencies|AForsk Foundation [19-725]; Swedish Government Strategic Research Area in Materials Science on Functional Materials at Linkoping University [2009-00971]; Lund University

In this work, we demonstrate an effective anion capturing in an aqueous medium using a highly porous carbon paper decorated with ZnO nanorods. A sol-gel technique was first employed to form a thin and compact seed layer of ZnO nanoparticles on the dense network of carbon fibers in the carbon paper. Subsequently, ZnO nanorods were successfully grown on the pre-seeded carbon papers using inexpensive chemical bath deposition. The prepared porous electrodes were electrochemically investigated for improved charge storage and stability under long-term operational conditions. The results show effective capacitive deionization with a maximum areal capacitance of 2 mF/cm(2), an energy consumption of 50 kJ per mole of chlorine ions, and an excellent long-term stability of the fabricated C-ZnO electrodes. The experimental results are supported by COMSOL simulations. Besides the demonstrated capacitive desalination application, our results can directly be used to realize suitable electrodes for energy storage in supercapacitors., Funding Agencies|AForsk Foundation [19-725]; Swedish Government Strategic Research Area in Materials Science on Functional Materials at Linkoping University [2009-00971]; Lund University

Early warning systems detect new psychoactive substances (NPS), while dedicated monitoring programs and routine drug and toxicology testing identify fluctuations in prevalence. We report the increasing prevalence of the synthetic cannabinoid receptor agonist (SCRA) ADB-BUTINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-butyl-1H-indazole-3-carbox-amide). ADB-BUTINACA was first detected in a seizure in Sweden in 2019, and we report its detection in 13 routine Swedish forensic toxicology cases soon after. In January 2021, ADB-BUTINACA was detected in SCRA-infused papers seized in Scottish prisons and has rapidly increased in prevalence, being detected in 60.4% of the SCRA-infused papers tested between January and July 2021. In this work, ADB-BUTINACA was incubated with human hepatocytes (HHeps), and 21 metabolites were identified in vitro, 14 being detected in authentic case samples. The parent drug and metabolites B9 (mono-hydroxylation on the n-butyl tail) and B16 (mono-hydroxylation on the indazole ring) are recommended biomarkers in blood, while metabolites B4 (dihydrodiol formation on the indazole core), B9, and B16 are suitable biomarkers in urine. ADB-4en-PINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-[pent-4-en-1-yl]-1H-indazole-3-carboxamide) was detected in Scottish prisons in December 2020, but, unlike ADB-BUTINACA, prevalence has remained low. ADB-4en-PINACA was incubated with HHeps, and 11 metabolites were identified. Metabolites E3 (dihydrodiol formed in the tail moiety) and E7 (hydroxylation on the linked/head group) are the most abundant metabolites in vitro and are suggested as urinary biomarkers. The in vitro potencies of ADB-BUTINACA (EC50, 11.5 nM and ADB-4en-PINACA (EC50, 11.6 nM) are similar to that of MDMB-4en-PINACA (EC50, 4.3 nM). A third tert-leucinamide SCRA, ADB-HEXINACA was also detected in prison samples and warrants further investigation., Funding Agencies|Linkopings Universitet; Dubai Police Force [2427681]; Leverhulme TrustLeverhulme Trust [RC-2015-01]; Scottish Prison Service [01865]; Linkoping University; VINNOVAVinnova [2019-03566]; European CommissionEuropean CommissionEuropean Commission Joint Research Centre [E! 113377]

Early warning systems detect new psychoactive substances (NPS), while dedicated monitoring programs and routine drug and toxicology testing identify fluctuations in prevalence. We report the increasing prevalence of the synthetic cannabinoid receptor agonist (SCRA) ADB-BUTINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-butyl-1H-indazole-3-carbox-amide). ADB-BUTINACA was first detected in a seizure in Sweden in 2019, and we report its detection in 13 routine Swedish forensic toxicology cases soon after. In January 2021, ADB-BUTINACA was detected in SCRA-infused papers seized in Scottish prisons and has rapidly increased in prevalence, being detected in 60.4% of the SCRA-infused papers tested between January and July 2021. In this work, ADB-BUTINACA was incubated with human hepatocytes (HHeps), and 21 metabolites were identified in vitro, 14 being detected in authentic case samples. The parent drug and metabolites B9 (mono-hydroxylation on the n-butyl tail) and B16 (mono-hydroxylation on the indazole ring) are recommended biomarkers in blood, while metabolites B4 (dihydrodiol formation on the indazole core), B9, and B16 are suitable biomarkers in urine. ADB-4en-PINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-[pent-4-en-1-yl]-1H-indazole-3-carboxamide) was detected in Scottish prisons in December 2020, but, unlike ADB-BUTINACA, prevalence has remained low. ADB-4en-PINACA was incubated with HHeps, and 11 metabolites were identified. Metabolites E3 (dihydrodiol formed in the tail moiety) and E7 (hydroxylation on the linked/head group) are the most abundant metabolites in vitro and are suggested as urinary biomarkers. The in vitro potencies of ADB-BUTINACA (EC50, 11.5 nM and ADB-4en-PINACA (EC50, 11.6 nM) are similar to that of MDMB-4en-PINACA (EC50, 4.3 nM). A third tert-leucinamide SCRA, ADB-HEXINACA was also detected in prison samples and warrants further investigation., Funding Agencies|Linkopings Universitet; Dubai Police Force [2427681]; Leverhulme TrustLeverhulme Trust [RC-2015-01]; Scottish Prison Service [01865]; Linkoping University; VINNOVAVinnova [2019-03566]; European CommissionEuropean CommissionEuropean Commission Joint Research Centre [E! 113377]

Printed paper-based electronics offers solutions to rising energy concerns by supplying flexible, environmentally friendly, low-cost infrastructure for portable and wearable electronics. Herein, we demonstrate a scalable spray-coating approach to fabricate tailored paper poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/cellulose nanofibril (CNF) electrodes for all-printed supercapacitors. Layer-by-layer spray deposition was used to achieve high-quality electrodes with optimized electrode thickness. The morphology of these electrodes was analyzed using advanced X-ray scattering methods, revealing that spray-coated electrodes have smaller agglomerations, resulting in a homogeneous film, ultimately suggesting a better electrode manufacturing method than drop-casting. The printed paper-based supercapacitors exhibit an areal capacitance of 9.1 mF/cm(2), which provides enough energy to power electrochromic indicators. The measured equivalent series resistance (ESR) is as low as 0.3 Omega, due to improved contact and homogeneous electrodes. In addition, a demonstrator in the form of a self-powered wearable wristband is shown, where a large-area (90 cm(2)) supercapacitor is integrated with a flexible solar cell and charged by ambient indoor light. This demonstration shows the tremendous potential for sequential coating/printing methods in the scaling up of printed wearables and self-sustaining systems., Funding Agencies|Swedish Foundation for Strategic Research; Knut and Alice Wallenberg Foundation (Wallenberg Wood Science Center); Onnesjo Foundation; EU SYMPHONY project (H2020) [862095]; DESY Strategic Fund (DSF)

Printed paper-based electronics offers solutions to rising energy concerns by supplying flexible, environmentally friendly, low-cost infrastructure for portable and wearable electronics. Herein, we demonstrate a scalable spray-coating approach to fabricate tailored paper poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/cellulose nanofibril (CNF) electrodes for all-printed supercapacitors. Layer-by-layer spray deposition was used to achieve high-quality electrodes with optimized electrode thickness. The morphology of these electrodes was analyzed using advanced X-ray scattering methods, revealing that spray-coated electrodes have smaller agglomerations, resulting in a homogeneous film, ultimately suggesting a better electrode manufacturing method than drop-casting. The printed paper-based supercapacitors exhibit an areal capacitance of 9.1 mF/cm(2), which provides enough energy to power electrochromic indicators. The measured equivalent series resistance (ESR) is as low as 0.3 Omega, due to improved contact and homogeneous electrodes. In addition, a demonstrator in the form of a self-powered wearable wristband is shown, where a large-area (90 cm(2)) supercapacitor is integrated with a flexible solar cell and charged by ambient indoor light. This demonstration shows the tremendous potential for sequential coating/printing methods in the scaling up of printed wearables and self-sustaining systems., Funding Agencies|Swedish Foundation for Strategic Research; Knut and Alice Wallenberg Foundation (Wallenberg Wood Science Center); Onnesjo Foundation; EU SYMPHONY project (H2020) [862095]; DESY Strategic Fund (DSF)

Printed paper-based electronics offers solutions to rising energy concerns by supplying flexible, environmentally friendly, low-cost infrastructure for portable and wearable electronics. Herein, we demonstrate a scalable spray-coating approach to fabricate tailored paper poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/cellulose nanofibril (CNF) electrodes for all-printed supercapacitors. Layer-by-layer spray deposition was used to achieve high-quality electrodes with optimized electrode thickness. The morphology of these electrodes was analyzed using advanced X-ray scattering methods, revealing that spray-coated electrodes have smaller agglomerations, resulting in a homogeneous film, ultimately suggesting a better electrode manufacturing method than drop-casting. The printed paper-based supercapacitors exhibit an areal capacitance of 9.1 mF/cm(2), which provides enough energy to power electrochromic indicators. The measured equivalent series resistance (ESR) is as low as 0.3 Omega, due to improved contact and homogeneous electrodes. In addition, a demonstrator in the form of a self-powered wearable wristband is shown, where a large-area (90 cm(2)) supercapacitor is integrated with a flexible solar cell and charged by ambient indoor light. This demonstration shows the tremendous potential for sequential coating/printing methods in the scaling up of printed wearables and self-sustaining systems., Funding Agencies|Swedish Foundation for Strategic Research; Knut and Alice Wallenberg Foundation (Wallenberg Wood Science Center); Onnesjo Foundation; EU SYMPHONY project (H2020) [862095]; DESY Strategic Fund (DSF)

In this work, we demonstrate an effective anion capturing in an aqueous medium using a highly porous carbon paper decorated with ZnO nanorods. A sol-gel technique was first employed to form a thin and compact seed layer of ZnO nanoparticles on the dense network of carbon fibers in the carbon paper. Subsequently, ZnO nanorods were successfully grown on the pre-seeded carbon papers using inexpensive chemical bath deposition. The prepared porous electrodes were electrochemically investigated for improved charge storage and stability under long-term operational conditions. The results show effective capacitive deionization with a maximum areal capacitance of 2 mF/cm(2), an energy consumption of 50 kJ per mole of chlorine ions, and an excellent long-term stability of the fabricated C-ZnO electrodes. The experimental results are supported by COMSOL simulations. Besides the demonstrated capacitive desalination application, our results can directly be used to realize suitable electrodes for energy storage in supercapacitors., Funding Agencies|AForsk Foundation [19-725]; Swedish Government Strategic Research Area in Materials Science on Functional Materials at Linkoping University [2009-00971]; Lund University

Early warning systems detect new psychoactive substances (NPS), while dedicated monitoring programs and routine drug and toxicology testing identify fluctuations in prevalence. We report the increasing prevalence of the synthetic cannabinoid receptor agonist (SCRA) ADB-BUTINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-butyl-1H-indazole-3-carbox-amide). ADB-BUTINACA was first detected in a seizure in Sweden in 2019, and we report its detection in 13 routine Swedish forensic toxicology cases soon after. In January 2021, ADB-BUTINACA was detected in SCRA-infused papers seized in Scottish prisons and has rapidly increased in prevalence, being detected in 60.4% of the SCRA-infused papers tested between January and July 2021. In this work, ADB-BUTINACA was incubated with human hepatocytes (HHeps), and 21 metabolites were identified in vitro, 14 being detected in authentic case samples. The parent drug and metabolites B9 (mono-hydroxylation on the n-butyl tail) and B16 (mono-hydroxylation on the indazole ring) are recommended biomarkers in blood, while metabolites B4 (dihydrodiol formation on the indazole core), B9, and B16 are suitable biomarkers in urine. ADB-4en-PINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-[pent-4-en-1-yl]-1H-indazole-3-carboxamide) was detected in Scottish prisons in December 2020, but, unlike ADB-BUTINACA, prevalence has remained low. ADB-4en-PINACA was incubated with HHeps, and 11 metabolites were identified. Metabolites E3 (dihydrodiol formed in the tail moiety) and E7 (hydroxylation on the linked/head group) are the most abundant metabolites in vitro and are suggested as urinary biomarkers. The in vitro potencies of ADB-BUTINACA (EC50, 11.5 nM and ADB-4en-PINACA (EC50, 11.6 nM) are similar to that of MDMB-4en-PINACA (EC50, 4.3 nM). A third tert-leucinamide SCRA, ADB-HEXINACA was also detected in prison samples and warrants further investigation., Funding Agencies|Linkopings Universitet; Dubai Police Force [2427681]; Leverhulme TrustLeverhulme Trust [RC-2015-01]; Scottish Prison Service [01865]; Linkoping University; VINNOVAVinnova [2019-03566]; European CommissionEuropean CommissionEuropean Commission Joint Research Centre [E! 113377]

Appropriate evaluation and experimental design are fundamental for empirical sciences, particularly in data-driven fields. Due to the successes in computational modeling of languages, for instance, research outcomes are having an increasingly immediate impact on end users. As the gap in adoption by end users decreases, the need increases to ensure that tools and models developed by the research communities and practitioners are reliable, trustworthy, and supportive of the users in their goals. In this position paper, we focus on the issues of evaluating visual text analytics approaches. We take an interdisciplinary perspective from the visualization and natural language processing communities, as we argue that the design and validation of visual text analytics include concerns beyond computational or visual/interactive methods on their own. We identify four key groups of challenges for evaluating visual text analytics approaches (data ambiguity, experimental design, user trust, and "big picture" concerns) and provide suggestions for research opportunities from an interdisciplinary perspective.

Printed paper-based electronics offers solutions to rising energy concerns by supplying flexible, environmentally friendly, low-cost infrastructure for portable and wearable electronics. Herein, we demonstrate a scalable spray-coating approach to fabricate tailored paper poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/cellulose nanofibril (CNF) electrodes for all-printed supercapacitors. Layer-by-layer spray deposition was used to achieve high-quality electrodes with optimized electrode thickness. The morphology of these electrodes was analyzed using advanced X-ray scattering methods, revealing that spray-coated electrodes have smaller agglomerations, resulting in a homogeneous film, ultimately suggesting a better electrode manufacturing method than drop-casting. The printed paper-based supercapacitors exhibit an areal capacitance of 9.1 mF/cm(2), which provides enough energy to power electrochromic indicators. The measured equivalent series resistance (ESR) is as low as 0.3 Omega, due to improved contact and homogeneous electrodes. In addition, a demonstrator in the form of a self-powered wearable wristband is shown, where a large-area (90 cm(2)) supercapacitor is integrated with a flexible solar cell and charged by ambient indoor light. This demonstration shows the tremendous potential for sequential coating/printing methods in the scaling up of printed wearables and self-sustaining systems., Funding Agencies|Swedish Foundation for Strategic Research; Knut and Alice Wallenberg Foundation (Wallenberg Wood Science Center); Onnesjo Foundation; EU SYMPHONY project (H2020) [862095]; DESY Strategic Fund (DSF)

Printed paper-based electronics offers solutions to rising energy concerns by supplying flexible, environmentally friendly, low-cost infrastructure for portable and wearable electronics. Herein, we demonstrate a scalable spray-coating approach to fabricate tailored paper poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/cellulose nanofibril (CNF) electrodes for all-printed supercapacitors. Layer-by-layer spray deposition was used to achieve high-quality electrodes with optimized electrode thickness. The morphology of these electrodes was analyzed using advanced X-ray scattering methods, revealing that spray-coated electrodes have smaller agglomerations, resulting in a homogeneous film, ultimately suggesting a better electrode manufacturing method than drop-casting. The printed paper-based supercapacitors exhibit an areal capacitance of 9.1 mF/cm(2), which provides enough energy to power electrochromic indicators. The measured equivalent series resistance (ESR) is as low as 0.3 Omega, due to improved contact and homogeneous electrodes. In addition, a demonstrator in the form of a self-powered wearable wristband is shown, where a large-area (90 cm(2)) supercapacitor is integrated with a flexible solar cell and charged by ambient indoor light. This demonstration shows the tremendous potential for sequential coating/printing methods in the scaling up of printed wearables and self-sustaining systems., Funding Agencies|Swedish Foundation for Strategic Research; Knut and Alice Wallenberg Foundation (Wallenberg Wood Science Center); Onnesjo Foundation; EU SYMPHONY project (H2020) [862095]; DESY Strategic Fund (DSF)

In this work, we demonstrate an effective anion capturing in an aqueous medium using a highly porous carbon paper decorated with ZnO nanorods. A sol-gel technique was first employed to form a thin and compact seed layer of ZnO nanoparticles on the dense network of carbon fibers in the carbon paper. Subsequently, ZnO nanorods were successfully grown on the pre-seeded carbon papers using inexpensive chemical bath deposition. The prepared porous electrodes were electrochemically investigated for improved charge storage and stability under long-term operational conditions. The results show effective capacitive deionization with a maximum areal capacitance of 2 mF/cm(2), an energy consumption of 50 kJ per mole of chlorine ions, and an excellent long-term stability of the fabricated C-ZnO electrodes. The experimental results are supported by COMSOL simulations. Besides the demonstrated capacitive desalination application, our results can directly be used to realize suitable electrodes for energy storage in supercapacitors., Funding Agencies|AForsk Foundation [19-725]; Swedish Government Strategic Research Area in Materials Science on Functional Materials at Linkoping University [2009-00971]; Lund University

In this work, we demonstrate an effective anion capturing in an aqueous medium using a highly porous carbon paper decorated with ZnO nanorods. A sol-gel technique was first employed to form a thin and compact seed layer of ZnO nanoparticles on the dense network of carbon fibers in the carbon paper. Subsequently, ZnO nanorods were successfully grown on the pre-seeded carbon papers using inexpensive chemical bath deposition. The prepared porous electrodes were electrochemically investigated for improved charge storage and stability under long-term operational conditions. The results show effective capacitive deionization with a maximum areal capacitance of 2 mF/cm(2), an energy consumption of 50 kJ per mole of chlorine ions, and an excellent long-term stability of the fabricated C-ZnO electrodes. The experimental results are supported by COMSOL simulations. Besides the demonstrated capacitive desalination application, our results can directly be used to realize suitable electrodes for energy storage in supercapacitors., Funding Agencies|AForsk Foundation [19-725]; Swedish Government Strategic Research Area in Materials Science on Functional Materials at Linkoping University [2009-00971]; Lund University

Early warning systems detect new psychoactive substances (NPS), while dedicated monitoring programs and routine drug and toxicology testing identify fluctuations in prevalence. We report the increasing prevalence of the synthetic cannabinoid receptor agonist (SCRA) ADB-BUTINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-butyl-1H-indazole-3-carbox-amide). ADB-BUTINACA was first detected in a seizure in Sweden in 2019, and we report its detection in 13 routine Swedish forensic toxicology cases soon after. In January 2021, ADB-BUTINACA was detected in SCRA-infused papers seized in Scottish prisons and has rapidly increased in prevalence, being detected in 60.4% of the SCRA-infused papers tested between January and July 2021. In this work, ADB-BUTINACA was incubated with human hepatocytes (HHeps), and 21 metabolites were identified in vitro, 14 being detected in authentic case samples. The parent drug and metabolites B9 (mono-hydroxylation on the n-butyl tail) and B16 (mono-hydroxylation on the indazole ring) are recommended biomarkers in blood, while metabolites B4 (dihydrodiol formation on the indazole core), B9, and B16 are suitable biomarkers in urine. ADB-4en-PINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-[pent-4-en-1-yl]-1H-indazole-3-carboxamide) was detected in Scottish prisons in December 2020, but, unlike ADB-BUTINACA, prevalence has remained low. ADB-4en-PINACA was incubated with HHeps, and 11 metabolites were identified. Metabolites E3 (dihydrodiol formed in the tail moiety) and E7 (hydroxylation on the linked/head group) are the most abundant metabolites in vitro and are suggested as urinary biomarkers. The in vitro potencies of ADB-BUTINACA (EC50, 11.5 nM and ADB-4en-PINACA (EC50, 11.6 nM) are similar to that of MDMB-4en-PINACA (EC50, 4.3 nM). A third tert-leucinamide SCRA, ADB-HEXINACA was also detected in prison samples and warrants further investigation., Funding Agencies|Linkopings Universitet; Dubai Police Force [2427681]; Leverhulme TrustLeverhulme Trust [RC-2015-01]; Scottish Prison Service [01865]; Linkoping University; VINNOVAVinnova [2019-03566]; European CommissionEuropean CommissionEuropean Commission Joint Research Centre [E! 113377]

Early warning systems detect new psychoactive substances (NPS), while dedicated monitoring programs and routine drug and toxicology testing identify fluctuations in prevalence. We report the increasing prevalence of the synthetic cannabinoid receptor agonist (SCRA) ADB-BUTINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-butyl-1H-indazole-3-carbox-amide). ADB-BUTINACA was first detected in a seizure in Sweden in 2019, and we report its detection in 13 routine Swedish forensic toxicology cases soon after. In January 2021, ADB-BUTINACA was detected in SCRA-infused papers seized in Scottish prisons and has rapidly increased in prevalence, being detected in 60.4% of the SCRA-infused papers tested between January and July 2021. In this work, ADB-BUTINACA was incubated with human hepatocytes (HHeps), and 21 metabolites were identified in vitro, 14 being detected in authentic case samples. The parent drug and metabolites B9 (mono-hydroxylation on the n-butyl tail) and B16 (mono-hydroxylation on the indazole ring) are recommended biomarkers in blood, while metabolites B4 (dihydrodiol formation on the indazole core), B9, and B16 are suitable biomarkers in urine. ADB-4en-PINACA (N-[1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-[pent-4-en-1-yl]-1H-indazole-3-carboxamide) was detected in Scottish prisons in December 2020, but, unlike ADB-BUTINACA, prevalence has remained low. ADB-4en-PINACA was incubated with HHeps, and 11 metabolites were identified. Metabolites E3 (dihydrodiol formed in the tail moiety) and E7 (hydroxylation on the linked/head group) are the most abundant metabolites in vitro and are suggested as urinary biomarkers. The in vitro potencies of ADB-BUTINACA (EC50, 11.5 nM and ADB-4en-PINACA (EC50, 11.6 nM) are similar to that of MDMB-4en-PINACA (EC50, 4.3 nM). A third tert-leucinamide SCRA, ADB-HEXINACA was also detected in prison samples and warrants further investigation., Funding Agencies|Linkopings Universitet; Dubai Police Force [2427681]; Leverhulme TrustLeverhulme Trust [RC-2015-01]; Scottish Prison Service [01865]; Linkoping University; VINNOVAVinnova [2019-03566]; European CommissionEuropean CommissionEuropean Commission Joint Research Centre [E! 113377]

Acute intoxication incidents due to neurotoxic organophosphate (OP) insecticides are occasionally reported, related either to suicidal attempts or occupational exposure due to the misuse of protective equipment. Among them, chlorpyrifos is a compound related to great controversy, which is still authorized and easily accessible in many countries around the world. However, to screen for its exposure markers, instrumental methods are commonly applied, which cannot enable rapid monitoring at an early stage of an intoxication. Therefore, in this study, a microfluidic paper-based analytical device (mu PAD) able to rapidly screen for chlorpyrifos-oxon, the toxic chlorpyrifos metabolite, in human serum was developed and fully validated. The mu PAD combines wax-printed butyrylcholinesterase (BChE) paper sensors, a lab-on-a-chip (LOC) prototype injector and a smartphone as the analytical detector. In principle, the wax-printed strips with adsorbed BChE are embedded into LOC injectors able to deliver samples and reagents on-demand. A smartphone reader was used to monitor the color development on the strips providing binary qualitative results. mu PAD method performance characteristics were thoroughly evaluated in terms of specificity, detection capability (CC beta) and ruggedness. The developed analytical platform is rapid (results within 10 min), cost-efficient (0.70 (sic)), potentially applicable at the point-of-need and attained a low CC beta (10 mu g L-1 in human serum). Finally, mu PAD characteristics were critically compared to wellestablished methods, namely an in-house BChE microplate assay and liquid chromatography tandem mass spectrometry., Funding Agencies|European Unions Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grantEuropean Union (EU) [720325]; METROFOOD-CZ research infrastructure project (MEYS Grant) [LM2018100]; [A2_FPBT_2020_013]