This thesis addresses the application of hybrid cold-formed steel (CFS) - Hot-Rolled Steel (HRS) structures, as a new lateral force resisting system for light weight steel framed buildings in seismic regions. The study considers hysteretic behaviour, as well as maximum lateral load resisting capacity through comprehensive testing and advanced numerical analyses. The study identifies the advantages and disadvantages of the proposed hybrid system and provides in depth knowledge about performance characteristics of this innovative structural system, in order to facilitate the use of this system in earthquake-prone regions. The project is divided into three main parts: experimental, numerical and analytical studies. A comprehensive literature review is performed as a part of this study, in order to discover the existing gaps in the current knowledge regarding the structural performance of CFS structures and the methods for lateral performance enhancement. The literature review suggests that although CFS walls are not new, and have been used as non-structural components for many years, their application as main load-bearing structural frames is relatively new. That is, appropriate guidelines that address the seismic design of CFS structures have not yet been fully developed in the literature. In addition, the lateral design of these systems is not adequately detailed in the available standards of practice. There have been several attempts to improve the seismic performance of such structural system by different bracing or sheathing configurations. However, there is minimal background information available on hybrid systems such as hot rolled-cold formed structures. In this study, a series of CFS-HRS hybrid shear walls are constructed in order to investigate the lateral behaviour of the walls with different configurations to obtain the optimum combination of HRS and CFS. Different configurations are considered to provide the most efficient load transfer pattern from cold formed steel part of the wall to the Hot Rolled section, which is responsible for withstanding the lateral loads. The CFS part is aimed to transfer lateral loads to HRS part without any internal local failure. The ideal failure condition is the HRS yielding. Therefore, the optimum rigidity of the HRS part is of great importance to prevent any local failure happening prior to reaching the maximum lateral capacity of the HRS. For each experimental specimen, the hysteretic envelope curve is plotted, and different characteristics are evaluated. Since the failure mode of such systems is very complicated, the test results will provide the possible failure modes to be utilised for any further investigation or any optimisation analysis in numerical and analytical studies. In addition, Non-linear finite element (FE) analysis is employed using the ABAQUS software [1], in order to investigate the seismic performance of the proposed hybrid shear walls in multi-storey light steel frames. The nonlinear analysis accounts for different structural characteristics, including material non-linearity, geometric imperfection and residual stresses. The numerical models are verified based on experimental test results. The principal objective of this part of the study is aseismic optimisation of the proposed hybrid system and finding the corresponding dimensions and configurations to improve the strength and stiffness to achieve the objective. Using the hybrid wall panel system, a 4-storey building in an earthquake prone region is designed as per the relevant codes of practice. For the designed 4-storey building, the CFS part of the panel only bears the gravity loads, while a hot rolled steel collector transfers the lateral load to the HRS part acting as the main lateral load resisting system. Finally, the building is designed using different lateral load resisting systems and the results are compared with those from the proposed hybrid system in terms of cost. Furthermore, based on the real failure mode shapes obtained from test specimens, a Finite Strip Method program is developed to evaluate the elastic buckling mode shapes of a single stud with an arbitrary section detail. The code is helpful for design of CFS studs as explained in Chapters 3 and 5.