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Paper Chromatography and Electrophoresis, Volume II presents methods, techniques and complete experimental procedures in paper chromatography. The book provides information and applications of paper chromatography such as the theory, mechanism, and fundamentals of the process; the separation of amino acids, carbohydrates, lipophilic steroids, and related compounds; and the separation and estimation of inorganic ions by paper chromatography. Chemists and laboratory researchers and technicians will find the book a valuable reference material.

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Paper Chromatography and Electrophoresis, Volume I: Electrophoresis in Stabilizing Media covers the general features of electrophoresis in stabilizing media. The book includes a consideration of the factors which determine the rate of movement of the compounds in an electrical field, the factors which must be controlled in order to obtain successful results, as well as the general arrangement and types of equipment used. The text also provides a description of methods for the separation of specific classes of compounds (amines, amino acids, peptides, proteins, nucleic acids, derivatives, and related compounds, carbohydrates, and organic acids and derivatives) normally encountered by chemists. Inorganic chemists, organic chemists, clinical chemists, and biochemists will find the book invaluable.

Chromatographic and Electrophoretic Techniques, Volume I — Chromatography focuses on techniques, processes, reactions, and methodologies involved in chromatography. The selection first ponders on paper chromatographic apparatus and techniques; desalting and related techniques; and apparatus and techniques in thin layer chromatography. Discussions focus on chromatographic solvents, location reagents, chemical conversions occurring during electrolytic desalting, electrodialysis, and ion exchange desalting. The book also examines paper chromatography, applications of thin layer chromatography in clinical biochemistry, and dinitro-phenyl aminoacids. The publication takes a look at iodoaminoacids and related compounds, indoles and related Ehrlich reactors, and imidazoles. The book also elaborates on guanidines, purines and pyrimidines and their derivatives, sugars, ketoacids, organic and phenolic acids, and chromatographic procedures. The selection is a dependable reference for biochemists and readers interested in chromatography.

Protides of the Biological Fluids contains the proceedings of the XVIIIth Colloquium held in Bruges, Belgium in 1970. The papers focus on protides of the biological fluids, with emphasis on three main topics related to protein chemistry: proteins during development and the recurrence of fetal proteins in cancer; protein-protein interactions; and trends and technical refinements in the insolubilization of proteins. This book is comprised of 95 chapters and begins with an assessment of the relationships and functions of the apoprotein and lipid moieties of lipoproteins, followed by a discussion on the characteristics and structure of the alpha-fetoproteins. The protein patterns in the post-natal period, as well as specific patterns encountered during development of the various organs, are then considered. Subsequent chapters explore the recurrence of various fetoproteins in hepatoma and in tumors of the digestive system; protein-protein interactions occurring during association or aggregation of some proteins such as myosin, fibrin, and casein; and preparation of insolubilized enzymes, together with the isolation and purification of antibodies. The final section is devoted to immunological studies and methods such as thin-layer ultracentrifugation. This monograph will be a useful resource for biologists and chemists alike.

Protides of the Biological Fluids: Twentieth Volume is a collection of studies about three selected topics from the general field of protein chemistry. The book is divided into four sections. Section A covers monoclonal immunoglobulins and its properties and structure; the amyloid substance; and antibody function. Section B covers active polypeptides derived from plasma proteins; the kinin system; the angiotensin and renin system; anaphylatoxins; and protease inhibitors. Section C covers microcalorimetry in biological systems; biological system and its relation with thermodynamics; and the application of microcalorimetry to biological systems. The book also includes a Section D, which does not consider any of the selected topics, but instead focuses on other techniques such as the double line method; radioimmunoassay of alpha-fetoprotein; and the IgM latex test. The text is recommended for students and reseearchers in the fields of biology, biochemistry, and other related fields, especially those who wish to learn more about monoclonal immunoglobulins, fibrinopeptides, and the effect of microcalorimetry in biological systems.

Electrophoresis: Theory, Methods, and Applications, Volume II focuses on the contributions of electrophoresis in the advancement of knowledge on proteins, as well as in the fields of biochemistry, physiology, and medicine. The selection first offers information on the interpretation of electrophoretic mobilities, including theories for other models, electrophoresis of polyelectrolytes, and theory for a rigid spherical particle. The text then takes a look at primary protein structures and nomenclature and identification of the normal human serum proteins. Discussions focus on principles of nomenclature of the serum constituents; methods of identification of an isolated antigen; principal methods used to study serum proteins; separation of mixtures of peptides and amino acids by high-voltage electrophoresis; and methods for determining the primary structure of proteins. The publication elaborates on inheritance of protein variation in human serum and antibodies and myeloma proteins. Topics include products of enzymic digestion, products of reduction, naturally occurring fragments, genetic variation, and variations detected in human serum proteins. The manuscript then examines lymph and cerebrospinal fluid, electrophoresis of gastrointestinal secretions, and high resolution techniques. The selection is a dependable source of data for readers interested in electrophoresis.