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This paper present the 5S methodology. 5S- simple but effective, lean manufacturing methodology that helps organizations to simplify, clean and sustain a productive work environment. There is a tremendous scope to implement 5S in apparel industry. This paper deals with the implementation of 5S methodology in apparel industry. 5S implementation has been carried out in trims store department, SQ Birichina Limited, Bangladesh. PDCA cycle has played an important role in the implementation of 5S. The problem has been identified during site assessment. Those problems has been solved by using 5S concept. Case study has helped to understand the before and after implementation of the scenery which has been discussed briefly. After 2(1st November to 30th January,2014) month working there, got the expected success. The result of this project is that space utilization 27% and time saving for searching file is 82%, not only that the junior employees in that region were more confident about their task. 5S best team price giving ceremony has held on 31.12.2014 which help to make employee more interested to sustain it. [ABSTRACT FROM AUTHOR]