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The purpose of the research is to develop a methodological assessment approach to the development of technological integration of manufacturing enterprises in the Russian Federation in the context of priority scientific and technological development of the Russian economy. The basic research methods are key provisions of management theory, organization theory, and modern theories of technological development. Methodological basis in the system, process, resource and matrix approaches. There were used a wide range of research methods: description, generalization and abstraction, classification, argumentation, analytical and graphic methods. Theoretical results of the research are the disclosure of specific features of assessing the development of technological integration and the classification of opportunities that will allow assessing the situation regarding the decisions made by all participants of technological integration. The applied results of the research are analytical and graphical assessments of options for the development of technological integration, based on a combination of pricing and technological policy, taking into account the consumed resources and prices. It is proved that the profit is significantly higher when using data on the ratio of supply and demand for all technological transitions: from obtaining the initial resources for the implementation of production activities to the sale of manufactured products to the production market. The article offers a computational and analytical method that allows you to apply operational monitoring, due to the vector orientation of which it becomes possible to promptly make regular adjustments to the key parameters of assessing the impact of technological integration on the results of production activities of manufacturing enterprises. [ABSTRACT FROM AUTHOR]