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Biosensors research combines molecular-level with system-level challenges. The molecular challenge is to rapidly and reliably detect very low concentrations of molecules in a complex biological sample. The system challenge is to find principles that enable the integration of a series of process steps in a disposable cartridge. This paper describes how both aspects can be served by the actuation and detection of magnetic particles, illustrated by the example of immunoassay biosensing. [ABSTRACT FROM AUTHOR]

Biosensors research combines molecular-level with system-level challenges. The molecular challenge is to rapidly and reliably detect very low concentrations of molecules in a complex biological sample. The system challenge is to find principles that enable the integration of a series of process steps in a disposable cartridge. This paper describes how both aspects can be served by the actuation and detection of magnetic particles, illustrated by the example of immunoassay biosensing. [ABSTRACT FROM AUTHOR]

Sandia National Laboratories Airworthiness Assurance Nondestructive Inspection Validation Center (AANC) provides independent and quantitative evaluations of new and enhanced inspection, to developers, users, and regulators of aircraft. Wayne State University (WSU) has developed and patented an inspection technique using high-power ultrasonic excitation and infrared technology to detect defects in a variety of materials. AANC and WSU are working together as part of the FAA Sonic Infrared Technology Transfer Program. The ultimate goal of the program is to implement Sonic IR in the aviation field where appropriate. The capability of Sonic IR imaging to detect cracks in components commonly inspected with magnetic particle or liquid penetrant inspection in the field is of interest to industry. © 2006 American Institute of Physics [ABSTRACT FROM AUTHOR]