Search

Frailty is associated with a higher risk of death among kidney transplant candidates. Currently available frailty indices are often based on clinical impression, physical exam or an accumulation of deficits across domains of health. In this paper we investigate a clustering based approach that partitions the data based on similarities between individuals to generate phenotypes of kidney transplant candidates. We analyzed a multicenter cohort that included several features typically used to determine an individual's level of frailty. We present a clustering based phenotyping approach, where we investigated two clustering approaches--i.e. neural network based Self-Organizing Maps (SOM) with hierarchical clustering, and KAMILA (KAy-means for MIxed LArge data sets). Our clustering results partition the individuals across 3 distinct clusters. Clusters were used to generate and study feature-level phenotypes of each group. [ABSTRACT FROM AUTHOR]

The human body experiences greater heat losses in underwater environment than in dry, normal atmosphere, due to the great heat capacity of water. Body temperature of divers in immersion was studied taking into account not only the water temperature but also the pressure the divers are subjected to. The equation that describes the total heat transfer- at both levels: skin and respiratory system- was theoretically established, considering conduction, convection and respiratory gas heating and humidification. The body temperature of the divers was measured in a series of dives at different depths of immersion, conducted in the wet simulator of the Diving Center, in Constanta. The experimental results were in good accordance with the temperature predicted by the mathematical model. Consequently, the mathematical model provides information on minimal time period of thermal comfort in immersion. It may be a useful tool for the divers to priory establish the diving duration and choose the protection equipment according to the water temperature and pressure, and the task they have to accomplish. [ABSTRACT FROM AUTHOR]

This paper looks at the how cricket (the first of the modern global sports to organise) was forged in the later eighteenth-century. It argues that this game organised unstable categories of class and gender in a new mythologised version of rural virtue. It examines literary, pictorial, and documentary sources to show how players both exemplified and defied the logic of early capitalism alongside paradoxes of performed "masculinity" and "femininity". Mythologised in terms of a protest against decadent modernity, it explodes within a culture of gambling, drinking and urban commodification.Given this sport enjoys a fan base greater than the entire population of North America and formed a prototype for the cricket becomes essential if one is to understand the concept of "sport" itself. "Sport" becomes a site where the gendered performance of self becomes a consumer spectacle, often within a context of social and/or physical danger ..PAT.-Unpublished Manuscript [ABSTRACT FROM AUTHOR]

Current state-of-the-art mathematical simulation techniques have now reached the point where the complex thermo-mechanical coupling associated with glass container forming can be successfully modeled. Comparisons of final container thickness profiles indicates that these algorithms offer promise toward developing and diagnosing forming technologies for producing higher quality containers in a more consistent manner. © 2004 American Institute of Physics [ABSTRACT FROM AUTHOR]

Assessment of vital signs is an essential part of surveillance of critically ill patients to detect condition changes and clinical deterioration. While most modern electronic medical records allow for vitals to be recorded in a structured format, the frequency and quality of what is electronically stored may differ from how often these measures are actually recorded. We created a tool that extracts blood pressure, heart rate, temperature, respiratory rate, blood oxygen saturation, and pain level from nursing and other clinical notes recorded in the course of inpatient care to supplement structured vital sign data. [ABSTRACT FROM AUTHOR]

The majority of hospital physiologic monitor alarms are not clinically actionable and contribute to alarm fatigue. In 2014, The Joint Commission declared alarm safety as a National Patient Safety Goal and urged prompt action by hospitals to mitigate the issue [1]. It has been demonstrated that vital signs in hospitalized children are quite different from currently accepted reference ranges [2]. Implementation of data-driven, age stratified vital sign parameters (Table 1) for alarms in this patient population could reduce alarm frequency. [ABSTRACT FROM AUTHOR]