1. A general microsimulation toolkit for patient specific predictions, treatment efficiency and life expectancy.
- Author
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Barendse, Rogier, Battes, Linda, Kardys, Isabella, Takkenberg, Hanneke, van der Putten, Niek, and Boersma, Eric
- Abstract
Microsimulation can be used to predict the prognosis of an individual patient based on a virtual patient population of copies of that patient. In this study we compare the outcomes of an existing validated microsimulation program that is designed to study valvular heart disease and a newly developed microsimulation program that is designed to study heart diseases in general. We studied in depth the results of both systems to model the prognosis of a 40 year old male patient undergoing allograft surgery. Furthermore we studied the model results in relation to age and sex to provide a general overview of the most important outcome variables including operative mortality, average survival time, average event free time and average time to reoperation. Our results show a good agreement between the two systems regarding all simulations of allograft surgery. We intend to use the newly developed software to explore other disease/event related prognostic models. [ABSTRACT FROM PUBLISHER]
- Published
- 2011