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Monodisperse poly(N-isopropylacrylamide) (PNIPA) nanogel latexes with temperature and magnetic field sensitivity were prepared and characterized. The phase transition of the latex was characterized by dynamic light scattering. Electrokinetic measurements revealed that the particles have a negative surface charge, which depends on the pH of the swelling medium. Incorporation of magnetite nanoparticles facilitates the separation of the gel beads and their application in targeted delivery in an external magnetic field. The incorporation of magnetic material does not modify the temperature sensitivity of the PNIPA latex. [ABSTRACT FROM AUTHOR]