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Your search keyword '"Yahata, A."' showing total 29 results
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29 results on '"Yahata, A."'

20. Hair, Nail Disorders — Experimental Results

Author

Toshitani, S., primary, Yahata, T., additional, Yasuda, M., additional, Nakayama, J., additional, Urabe, H., additional, Hertel, H., additional, Gollnick, H., additional, Matthies, C., additional, Baumann, I., additional, and Orfanos, C. E., additional

Published
1988
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26. Cell Engineering Using Integrase and Recombinase Systems

Author

Sone, Takefumi, primary, Nishiumi, Fumiko, additional, Yahata, Kazuhide, additional, Sasaki, Yukari, additional, Kishine, Hiroe, additional, Andoh, Taichi, additional, Inoue, Ken, additional, Imamoto, Fumio, additional, Thyagarajan, Bhaskar, additional, and Chesnut, Jonathan D., additional

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28. Humanizing Bone Marrow in Immune-Deficient Mice.

Author

Compans, Richard W., Cooper, Max D., Honjo, Tasuku, Koprowski, Hilary, Melchers, Fritz, Oldstone, Michael B. A., Olsnes, Sjur, Vogt, Peter K., Nomura, Tatsuji, Watanabe, Takeshi, Habu, Sonoko, Ando, K., Muguruma, Y., and Yahata, T.

Abstract

Humanized mice are useful for studying human hematopoietic stem cells (HSCs) and their niche. In particular, clonal study of human HSC enables precise comparison of in vivo behavior between murine and human HSCs. A single HSC is able to reconstitute hematopoiesis even after serial transplantations in mice. While the life span of somatic cells is over that of individual in mice, this is not the case in humans. Clonal studies of human HSCs clearly demonstrated their aging in hosts. Since murine studies have demonstrated that HSCs are protected from aging by their niche in bone marrow, the humanizing niche model will reveal the precise mechanism by which human HSCs are protected from exhaustion in vivo. Direct transplantation of human mesenchymal stem cells into mouse bone marrow results in reconstitution of the functional human hematopoietic microenvironment comprised of pericytes, myofibroblasts, reticular cells, osteocytes in bone, bone-lining osteoblasts, and endothelial cells. These humanized mouse models are essential for testing whether the insights on hematopoiesis from mouse studies are applicable to humans before clinical application. [ABSTRACT FROM AUTHOR]

Published
2008
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29. The Star Formation Density in the High-Redshift Universe.

Author

Cristiani, Stefano, Renzini, Alvio, Williams, Robert E., Fernández-Soto, Alberto, Lanzetta, Kenneth M., Chen, Hsiao-Wen, Pascarelle, Sebastian M., and Yahata, Noriaki

Abstract

We use images of the Hubble Deep Fields (HDFs) to estimate the universal star formation density (SFD) and its evolution. We find that it increases with z to the highest redshifts explored, and that cosmological dimming must be taken into account to measure this quantity. A direct comparison with the properties of high-z DLAs shows perfect agreement with our analysis, providing encouraging evidence to its validity. [ABSTRACT FROM AUTHOR]

Published
2001
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