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Remodeling of neuromuscular junctions (NMJs) and ensuing -structural and functional plasticity occurs with aging. Age-related changes result from -reductions in physical activity, loss of motor neurons, and decreased muscle fiber size (sarcopenia). The properties of motor neurons and muscle fibers are precisely matched. In addition, motor unit recruitment in a selective manner is a primary mechanism by which the nervous system controls muscle contraction. Thus, it is essential to consider motor unit (and muscle fiber) type in any age-related -plasticity. The following chapter examines changes in motor unit properties associated with aging and how these affect structural and functional remodeling at NMJs. [ABSTRACT FROM AUTHOR]