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A new method is introduce for the three-dimensional (3D) reconstruction of the coronary stents in-vivo utilizing two-dimensional projection images acquired during rotational angiography (RA). The method is based on the application of motion compensated techniques to the acquired angiograms resulting in a temporal snapshot of the stent within the cardiac cycle. For the first time results of 3D reconstructed coronary stents in vivo, with high spatial resolution are presented. The proposed method allows for a comprehensive and unique quantitative 3D assessment of stent expansion that rivals current x-ray and intravascular ultrasound techniques. [ABSTRACT FROM AUTHOR]

The clinical application of three-dimensional (3D) imaging technology represents a powerful advancement in the diagnosis and treatment of patients with vascular disease. From its initial use with noninvasive imaging modalities like computed tomography (CT), 3D imaging technology is now used during invasive angiographic procedures for the diagnosis of vascular disease and guidance during therapeutic interventions. Threedimensional angiography resolves and streamlines many of the challenges of traditional two-dimensional (2D) angiography. Whereas traditional angiography relies heavily upon the experience of the operator to minimize the imaging limitations introduced by its 2D format, 3D angiography provides an objective, operator-independent method of acquiring more angiographic information to guide clinical decisions and patient care. As an interventional imaging tool, 3D angiography has the potential to simplify complex procedures, reduce radiation exposure, and improve patient outcomes. In this chapter, we explore the techniques and development of 3D angiography and the potential clinical and research applications of this powerful technology. [ABSTRACT FROM AUTHOR]