1. Endoscopic Ablation of Barrett΄s Esophagus and Early Esophageal Cancer.
- Author
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Litle, Virginia R., Watson, Thomas J., and Peters, Jeffrey H.
- Abstract
Barrett΄s esophagus develops as a result of chronic, pathologic reflux of gastro-duodenal contents into the esophagus. The diagnosis is made upon the endoscopic finding of columnar lined epithelium in the distal esophagus associated with specialized intestinal metaplasia (IM) on histology [1, 2]. Barrett΄s esophagus is classified as non-dysplastic IM, low-grade dysplasia (LGD), or high-grade dysplasia (HGD). Population-based studies suggest that Barrett΄s esophagus is present in 1–2% of the US adult population [3] and is increasing in prevalence [4]. Screening upper endoscopy in patients undergoing colonoscopy has shown a remarkably high prevalence, varying from 7% to as much as 25% depending upon the population screened. In a general population of patients undergoing colonoscopy, Rex et al. reported that 6.8% were found to have esophageal intestinal metaplasia [5]. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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