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Your search keyword '"Brook, G.A."' showing total 2 results
Start Over Author "Brook, G.A." Publication Type Books
2 results on '"Brook, G.A."'

1. Einsatz von transdifferenzierten adulten mesenchymalen Vorläuferzellen und bioartifiziellen-mikrostrukturierten Nervenleitschienen zur Regeneration peripherer Nerven

Author

Bozkurt, A., primary, Brook, G.A., additional, Scheffel, J., additional, Böcker, A., additional, Montzka, K., additional, O’Dey, D., additional, Möllers, S., additional, Deumens, R., additional, Schügner, F., additional, Heschel, I., additional, Wöltje, M., additional, Tolba, R., additional, Schwendt, T., additional, Janzen, C., additional, Weis, J., additional, and Pallua, N., additional

Published
2010
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2. Einsatz von transdifferenzierten adulten mesenchymalen Vorläuferzellen und bioartifiziellen-mikrostrukturierten Nervenleitschienen zur Regeneration peripherer Nerven.

Author

Bozkurt, A., Brook, G.A., Scheffel, J., Böcker, A., Montzka, K., O΄Dey, D., Möllers, S., Deumens, R., Schügner, F., Heschel, I., Wöltje, M., Tolba, R., Schwendt, T., Janzen, C., Weis, J., and Pallua, N.

Abstract

Regeneration in the peripheral nervous system is a major challenge in reconstructive plastic surgery. The goal of the current neuro-tissue engineering concept is the transdifferentiation of bone marrow stromal cells into Schwann cell-like cells in combination with a bioartificial nerve graft on the basis of a specifically designed cylindrical collagen scaffold. The patented cylindrical nerve guides resulted in an advanced interaction with the cells. In-vivo regeneration experiments (Lewis rats) revealed appropriate regeneration with axonal sprouting reaching the distal end of the nerve guide in an orientated manner over a distance of 2 cm within 12 weeks. [ABSTRACT FROM AUTHOR]

Published
2010
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