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12. Evaluation of Individual-Cell Motility

Author

Walmod, Peter S., primary, Hartmann-Petersen, Rasmus, additional, Berezin, Anton, additional, Prag, Søren, additional, Kiselyov, Vladislav V., additional, Berezin, Vladimir, additional, and Bock, Elisabeth, additional

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14. Evaluation of Cell Morphology.

Author

Walker, John M., Gavin, Ray H., Lepekhin, Eugene A., Walmod, Peter S., Berezin, Anton, Berezin, Vladimir, and Bock, Elisabeth

Abstract

The shape of a cell reflects cell-substratum and cell-cell attachment and organization of the cytoskeleton (1-4). Many studies on cell morphology have until recently been purely qualitative for the simple reason that morphological changes resulting from e.g., modulation of cell attachment or perturbation of cytoskeletal components often are so pronounced that quantification may seem unnecessary. However, quantitative determination of cellular morphology greatly expands the possibility of characterizing the role and regulation of macromolecules involved, e.g., in cytoskeletal functions and cellular differentiation. [ABSTRACT FROM AUTHOR]

Published
2001
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15. Evaluation of Individual-Cell Motility.

Author

Walker, John M., Gavin, Ray H., Walmod, Peter S., Hartmann-Petersen, Rasmus, Berezin, Anton, Prag, Søren, Kiselyov, Vladislav V., Berezin, Vladimir, and Bock, Elisabeth

Abstract

The coordinated displacement of a cell is a highly complex process which relies on the integration of a series of signaling pathways and on the function of a large number of molecular components including all main structures of the cytoskeleton (1,2). Thus, a detailed knowledge of the regulation and function of the cytoskeleton is of central importance for the understanding of cell motility, and conversely, investigations of cell motility may shed light on the function of cytoskeletal components. [ABSTRACT FROM AUTHOR]

Published
2001
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