46 results on '"A. Byzova"'
Search Results
2. Inap
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
3. Interferon-Inducible RNA-Dependent Protein Kinase
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
4. Integrin α1 (ITGA1)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
5. Interferon-Inducible eIF2α Kinase
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
6. Icmt (Isoprenylcysteine Carboxyl Methyltransferase)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
7. IL-1 Inducible Nuclear Ankyrin-Repeat Protein (INAP)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
8. Integrin Alpha 11
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
9. Inositol 1,4,5-trisphosphate-associated cGMP kinase substrate
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
10. Interleukin-7
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
11. int-2
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
12. Integrin-Associated Protein
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
13. Insulin-like Growth Factor Receptor Type I (IGF1R) Signaling and Inflammation
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
14. Interferon Regulatory Factor 5, IRF5
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
15. Inositol Polyphosphate-5-Phosphatase, 145 kDa
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
16. Integrin Alpha 4
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
17. ITPK1 (Inositol 1,3,4-Triphosphate 5/6 Kinase)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
18. Integrin Alpha 4 (Itga 4)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
19. IFN-β2
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
20. Integrin-Associated Signal Transducer
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
21. IFN-Gamma
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
22. Immune IFN
- Author
-
Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
23. IkB-zeta
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
24. Inositol 3,4,5,6-Tetrakisphosphate 1-Kinase
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
25. Interleukin-1 Signal Transducer
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
26. Inhibitor of DNA Binding 4 (ID4)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
27. IP-10
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
28. IP3 Receptor–Associated cGMP Kinase Substrate A
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
29. Inhibitor of Apoptosis (IAP) Proteins
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
30. Ionotropic Glutamate Receptors (AMPA, Kainate and NMDA Receptors)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
31. Integrin Alpha V (ITGAV)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
32. Immunity-Related GTPases (IRG)
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
33. IFN-γ
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
34. IP3 Receptors
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
35. Inositol Trisphosphate 5/6-Kinase
- Author
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Appleton, Kathryn M., primary, Cushman, Ian, additional, Peterson, Yuri K., additional, Manavalan, Balachandran, additional, Basith, Shaherin, additional, Choi, Sangdun, additional, Kimura, Akihiro, additional, Naka, Tetsuji, additional, Kishimoto, Tadamitsu, additional, Seddon, Benedict, additional, Traver, Maria, additional, Taylor, Gregory A., additional, Gyrd-Hansen, Mads, additional, Blandino, Giovanni, additional, Fontemaggi, Giulia, additional, Grillo, Michael A., additional, Koulen, Peter, additional, Annenkov, Alexander, additional, Zeltz, Cédric, additional, Gullberg, Donald, additional, Mittelbrunn, Maria, additional, Sánchez-Madrid, Francisco, additional, Kerr, Bethany A., additional, Byzova, Tatiana V., additional, Heino, Jyrki, additional, Lin, Fan-ching, additional, Young, Howard A., additional, Taylor, Colin W., additional, Barnes, Betsy J., additional, Zhou, Yixing, additional, Schenk, Tobias M. H., additional, Shears, Stephen B., additional, Sengar, Ameet S., additional, Salter, Michael W., additional, and Egan, Sean E., additional
- Published
- 2012
- Full Text
- View/download PDF
36. Chapter 11 Vascular Integrin Signaling
- Author
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Mahabeleshwar, Ganapati H., primary and Byzova, Tatiana V., additional
- Published
- 2008
- Full Text
- View/download PDF
37. High-sensitive technologies for molecular diagnostics of potato virus and viroid infections
- Author
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Drygin, Yu.F., primary, Chirkov, S.N., additional, Kondakova, O.A., additional, Zinovkin, R.A., additional, Ivanov, P.A., additional, Blintsov, A.N., additional, Gavryushina, E.S., additional, Zherdev, A.V., additional, Byzova, N.A., additional, Dzantiev, B.B., additional, and Atabekov, J.G., additional
- Published
- 2007
- Full Text
- View/download PDF
38. Immunochemical Approaches for Rapid Detection of Biologically Active Compounds
- Author
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Dzantiev, B. B., primary, Zherdev, A.V, additional, and Byzova, N.A., additional
- Published
- 2005
- Full Text
- View/download PDF
39. Platelet receptors: fibrinogen
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Plow, Edward F., primary, Haas, Thomas A., additional, and Byzova, Tatiana V., additional
- Published
- 2002
- Full Text
- View/download PDF
40. Specific haemoglobin content as an ecological characteristic in earthworms (Lumbricidae)
- Author
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Byzova, J. B., primary
- Published
- 1975
- Full Text
- View/download PDF
41. Rate of Temperature Adaptation of Respiratory Metabolism in Soil Invertebrates
- Author
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Byzova, Yu. B., primary
- Published
- 1982
- Full Text
- View/download PDF
42. Methods for Isolation of Endothelial and Smooth Muscle Cells and In Vitro Proliferation Assays
- Author
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Mahabeleshwar, Ganapati H., primary, Somanath, Payaningal R., additional, and Byzova, Tatiana V., additional
- Full Text
- View/download PDF
43. Platelets and Prothrombin
- Author
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Kalafatis, Michael, primary, Negrescu, Emil, additional, Byzova, Tatiana, additional, and Plow, Edward F., additional
- Full Text
- View/download PDF
44. Methods for Isolation of Endothelial and Smooth Muscle Cells and In Vitro Proliferation Assays.
- Author
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Walker, John M., Wang, Qing K., Mahabeleshwar, Ganapati H., Somanath, Payaningal R., and Byzova, Tatiana V.
- Abstract
Angiogenesis, the formation of new blood vessel from pre-existing blood vessel, occurs in a variety of normal and pathological conditions. It is complex morphogenetic process involving the coordinate migration, invasion, and reorganization of several cell types including endothelial cells, pericytes, smooth muscle cells, and stromal fibroblasts. The angiogenic response begins with excess protease secretion to facilitate basement membrane remodeling, proliferation of endothelial cells, and endothelial cell migration to form capillary network and lumen closure. In this chapter, we describe the methods to isolate mouse and human endothelial cells, smooth muscle cells, which will provide abundant, convenient and useful tool for the investigation of many aspects of endothelial cell biology. The high degrees of functional diversity have been observed from endothelial cells derived from different organs, and within the different vascular beds of a given organ. Therefore, this apparent heterogeneity has highlighted the requirement for the endothelial cell isolation and culture from a variety of tissues of different species in order to establish more realistic in vitro angiogenic models. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
- View/download PDF
45. Immunochemical Approaches for Rapid Detection of Biologically Active Compounds.
- Author
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Morrison, Dennis, Milanovich, Fred, Ivnitski, Dmitri, Austin, Thomas R., Dzantiev, B. B., Zherdev, A.V, and Byzova, N.A.
- Abstract
Express immunochemical techniques for determination of toxic compounds and pathogenic cells have been developed. Separation of reactants based on interaction between oppositely charged polyelectrolytes, namely polycation poly-N-ethyl-4-vinylpyridium and polyanion polymethacrylate, were used to reduce assay time. An extremely high rate and affinity of this interaction allowed formation of an immune complex in the solution followed by a quick separation of reactants. The polyelectrolyte-based assays were performed in both homogeneous and filtration formats. Total duration of the assay was 15– 20 min, limit of pesticides detection — down to 0.2 ng/ml. The polyelectrolyte separation has been also used in electrochemical immunosensors. The assay protocol is based on the measurement of pH changes induced by a peroxidase label. A field-effect transistor is the sensitive element of the sensor, and specific immune complexes are formed at disposable porous membranes. An alternative approach is based on the application of screen-printed electrode with impregnated peroxidase. The set of reactants was used together with a portable amperometric device designed for express monitoring of hazardous compounds under out-of-lab conditions. The total assay time was 20 min, and the detection limit was 0.2 ng/ml. Immunochromatographic tests based on colloidal gold particles conjugated with antibodies have been developed for detection of low molecular weight antigens and bacterial cells. The method allows detection of bacterial cells including Mycobacterium tuberculosis and Legionella pneumophila during 10 min in concentrations down to 104 cell/ml [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
46. Platelets and Prothrombin.
- Author
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Cannon, Christopher P., Quinn, Martin, Fitzgerald, Desmond, Kalafatis, Michael, Negrescu, Emil, Byzova, Tatiana, and Plow, Edward F.
- Abstract
Blood coagulation is initiated following injury to the blood vessel wall through the exposure of tissue factor, which mediates the activation of circulating factor VII. Activated factor VIIa forms a complex with tissue factor and triggers the subsequent steps in the activation of the coagulation system, ultimately culminating in the conversion of prothrombin to thrombin (1-5). The platelet membrane surface is crucial for this process, providing a milieu, referred to as the prothrombinase complex, for efficient assembly of the coagulation complexes and localization of the procoagulant response. Indeed, recent data have even implicated platelets in the initiation of coagulation as they acquire circulating forms of tissue factor, generated from other cells, on their surface (6,7). Thrombin mediates fibrin formation and plays a critical role in the inflammatory responses (8); thus, the regulation of prothrombin activation by the platelet membrane has broad physiological and pathophysiological implications. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
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