119 results on '"van den Hazel, Peter"'
Search Results
2. Adopting a child perspective for exposome research on mental health and cognitive development - Conceptualisation and opportunities.
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Persson Waye, Kerstin, Löve, Jesper, Lercher, Peter, Dzhambov, Angel M., Klatte, Maria, Schreckenberg, Dirk, Belke, Christin, Leist, Larisa, Ristovska, Gordana, Jeram, Sonja, Kanninen, Katja M., Selander, Jenny, Arat, Arzu, Lachmann, Thomas, Clark, Charlotte, Botteldooren, Dick, White, Kim, Julvez, Jordi, Foraster, Maria, Kaprio, Jaakko, Bolte, Gabriele, Psyllidis, Achilleas, Gulliver, John, Boshuizen, Hendriek, Bozzon, Alessandro, Fels, Janina, Hornikx, Maarten, van den Hazel, Peter, Weber, Miriam, Brambilla, Marco, Braat-Eggen, Ella, Van Kamp, Irene, and Vincens, Natalia
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- 2023
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3. Governing heatwaves in Europe: comparing health policy and practices to better understand roles, responsibilities and collaboration
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Vanderplanken, Kirsten, van den Hazel, Peter, Marx, Michael, Shams, Ahmad Zia, Guha-Sapir, Debarati, and van Loenhout, Joris Adriaan Frank
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- 2021
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4. Early environmental quality and life-course mental health effects: The Equal-Life project
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Kamp, Irene van, Persson Waye, Kerstin, Kanninen, Katja, Gulliver, John, Bozzon, Alessandro, Psyllidis, Achilleas, Boshuizen, Hendriek, Selander, Jenny, van den Hazel, Peter, Brambilla, Marco, Foraster, Maria, Julvez, Jordi, Klatte, Maria, Jeram, Sonja, Lercher, Peter, Botteldooren, Dick, Ristovska, Gordana, Kaprio, Jaakko, Schreckenberg, Dirk, Hornikx, Maarten, Fels, Janina, Weber, Miriam, Braat-Eggen, Ella, Hartmann, Julia, Clark, Charlotte, Vrijkotte, Tanja, Brown, Lex, and Bolte, Gabriele
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- 2022
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5. Positive health effects of the natural outdoor environment in typical populations in different regions in Europe (PHENOTYPE): a study programme protocol
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Nieuwenhuijsen, Mark J, Kruize, Hanneke, Gidlow, Christopher, Andrusaityte, Sandra, Antó, Josep Maria, Basagaña, Xavier, Cirach, Marta, Dadvand, Payam, Danileviciute, Asta, Donaire-Gonzalez, David, Garcia, Judith, Jerrett, Michael, Jones, Marc, Julvez, Jordi, van Kempen, Elise, van Kamp, Irene, Maas, Jolanda, Seto, Edmund, Smith, Graham, Triguero, Margarita, Wendel-Vos, Wanda, Wright, John, Zufferey, Joris, van den Hazel, Peter Jan, Lawrence, Roderick, and Grazuleviciene, Regina
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Public Health ,Health Sciences ,Prevention ,Aetiology ,2.2 Factors relating to the physical environment ,Life on Land ,Environment Design ,Environmental Exposure ,Europe ,Health Policy ,Health Status ,Humans ,Interpersonal Relations ,Mental Health ,Motor Activity ,Stress ,Psychological ,Urban Health ,Green space ,Blue space ,Health ,Well being ,Physical activity ,Clinical Sciences ,Public Health and Health Services ,Other Medical and Health Sciences ,Biomedical and clinical sciences ,Health sciences ,Psychology - Abstract
IntroductionGrowing evidence suggests that close contact with nature brings benefits to human health and well-being, but the proposed mechanisms are still not well understood and the associations with health remain uncertain. The Positive Health Effects of the Natural Outdoor environment in Typical Populations in different regions in Europe (PHENOTYPE) project investigates the interconnections between natural outdoor environments and better human health and well-being.Aims and methodsThe PHENOTYPE project explores the proposed underlying mechanisms at work (stress reduction/restorative function, physical activity, social interaction, exposure to environmental hazards) and examines the associations with health outcomes for different population groups. It implements conventional and new innovative high-tech methods to characterise the natural environment in terms of quality and quantity. Preventive as well as therapeutic effects of contact with the natural environment are being covered. PHENOTYPE further addresses implications for land-use planning and green space management. The main innovative part of the study is the evaluation of possible short-term and long-term associations of green space and health and the possible underlying mechanisms in four different countries (each with quite a different type of green space and a different use), using the same methodology, in one research programme. This type of holistic approach has not been undertaken before. Furthermore there are technological innovations such as the use of remote sensing and smartphones in the assessment of green space.ConclusionsThe project will produce a more robust evidence base on links between exposure to natural outdoor environment and human health and well-being, in addition to a better integration of human health needs into land-use planning and green space management in rural as well as urban areas.
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- 2014
6. Threats, challenges and opportunities for paediatric environmental health in Europe, Latin America and the Caribbean
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Ortega-García, Juan Antonio, Tellerías, Lydia, Ferrís-Tortajada, Josep, Boldo, Elena, Campillo-López, Ferran, van den Hazel, Peter, Cortes-Arancibia, Sandra, Ramis, Rebeca, Gaioli, Marisa, Monroy-Torres, Rebeca, Farias-Guardia, Constanza, Borras, Mirta, Yohannessen, Karla, García-Noriega-Fernández, Marcelino, Cárceles-Álvarez, Alberto, Jaimes-Vega, Diana Carolina, Cordero-Rizo, Marcia, López-Hernández, Fernando, and Claudio, Luz
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- 2019
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7. Amenazas, desafíos y oportunidades para la salud medioambiental pediátrica en Europa, América Latina y el Caribe
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Ortega-García, Juan Antonio, Tellerías, Lydia, Ferrís-Tortajada, Josep, Boldo, Elena, Campillo-López, Ferran, van den Hazel, Peter, Cortes-Arancibia, Sandra, Ramis, Rebeca, Gaioli, Marisa, Monroy-Torres, Rebeca, Farias-Guardia, Constanza, Borras, Mirta, Yohannessen, Karla, García-Noriega-Fernández, Marcelino, Cárceles-Álvarez, Alberto, Jaimes-Vega, Diana Carolina, Cordero-Rizo, Marcia, López-Hernández, Fernando, and Claudio, Luz
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- 2019
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8. In-Traffic Air Pollution Exposure and CC16, Blood Coagulation, and Inflammation Markers in Healthy Adults
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Zuurbier, Moniek, Hoek, Gerard, Oldenwening, Marieke, Meliefste, Kees, Krop, Esmeralda, van den Hazel, Peter, and Brunekreef, Bert
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- 2011
9. Respiratory Effects of Commuters' Exposure to Air Pollution in Traffic
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Zuurbier, Moniek, Hoek, Gerard, Oldenwening, Marieke, Meliefste, Kees, van den Hazel, Peter, and Brunekreef, Bert
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- 2011
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10. Commuters' Exposure to Particulate Matter Air Pollution Is Affected by Mode of Transport, Fuel Type, and Route
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Zuurbier, Moniek, Hoek, Gerard, Oldenwening, Marieke, Lenters, Virissa, Meliefste, Kees, van den Hazel, Peter, and Brunekreef, Bert
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- 2010
11. The challenge of social networking in the field of environment and health
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van den Hazel Peter, Keune Hans, Randall Scott, Yang Aileen, Ludlow David, and Bartonova Alena
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Industrial medicine. Industrial hygiene ,RC963-969 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background The fields of environment and health are both interdisciplinary and trans-disciplinary, and until recently had little engagement in social networking designed to cross disciplinary boundaries. The EU FP6 project HENVINET aimed to establish integrated social network and networking facilities for multiple stakeholders in environment and health. The underlying assumption is that increased social networking across disciplines and sectors will enhance the quality of both problem knowledge and problem solving, by facilitating interactions. Inter- and trans-disciplinary networks are considered useful for this purpose. This does not mean that such networks are easily organized, as openness to such cooperation and exchange is often difficult to ascertain. Methods Different methods may enhance network building. Using a mixed method approach, a diversity of actions were used in order to investigate the main research question: which kind of social networking activities and structures can best support the objective of enhanced inter- and trans-disciplinary cooperation and exchange in the fields of environment and health. HENVINET applied interviews, a role playing session, a personal response system, a stakeholder workshop and a social networking portal as part of the process of building an interdisciplinary and trans-disciplinary network. Results The interviews provided support for the specification of requirements for an interdisciplinary and trans-disciplinary network. The role playing session, the personal response system and the stakeholder workshop were assessed as useful tools in forming such network, by increasing the awareness by different disciplines of other’s positions. The social networking portal was particularly useful in delivering knowledge, but the role of the scientist in social networking is not yet clear. Conclusions The main challenge in the field of environment and health is not so much a lack of scientific problem knowledge, but rather the ability to effectively communicate, share and use available knowledge for policy making. Structured social network facilities can be useful by policy makers to engage with the research community. It is beneficial for scientists to be able to integrate the perspective of policy makers in the research agenda, and to assist in co-production of policy-relevant information. A diversity of methods need to be applied for network building: according to the fit-for-purpose-principle. It is useful to know which combination of methods and in which time frame produces the best results. Networking projects such as HENVINET are created not only for the benefit of the network itself, but also because the applying of the different methods is a learning tool for future network building. Finally, it is clear that the importance of specialized professionals in enabling effective communication between different groups should not be underestimated.
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- 2012
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12. In search of a common European approach to a healthy indoor environment
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Adan, Olaf C.G., Ng-A-Tham, Julie, Hanke, Wojtek, Sigsgaard, Torben, van den Hazel, Peter, and Wu, Felicia
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European Union -- Environmental policy ,European Union. European Commission -- Environmental policy ,Environmental health ,Indoor air quality ,Public health - Abstract
Increasingly, policymakers in Europe and around the world are realizing the importance of healthy indoor environments for public health. Certain member states of the European Union (EU) have already achieved [...]
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- 2007
13. The Faroes Statement: Human Health Effects of Developmental Exposure to Chemicals in Our Environment
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Grandjean, Philippe, Bellinger, David, Bergman, Åke, Cordier, Sylvaine, Davey-Smith, George, Eskenazi, Brenda, Gee, David, Gray, Kimberly, Hanson, Mark, van den Hazel, Peter, Heindel, Jerrold J., Heinzow, Birger, Hertz-Picciotto, Irva, Hu, Howard, Huang, Terry T-K, Jensen, Tina Kold, Landrigan, Philip J., McMillen, I. Caroline, Murata, Katsuyuki, Ritz, Beate, Schoeters, Greet, Skakkebæk, Niels Erik, Skerfving, Staffan, and Weihe, Pal
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- 2008
14. News from the EUPHA Section on Environment-related Diseases
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van den Hazel, Peter
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- 2007
15. Lead neurotoxicity in children: is prenatal exposure more important than postnatal exposure?
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Ronchetti, Roberto, van den Hazel, Peter, Schoeters, Greet, Hanke, Wojtek, Rennerova, Zuzana, Barreto, Mario, and Villa, Maria Pia
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- 2007
16. Exposure to multiple environmental agents and their effect
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KOPPE, JANNA G., BARTONOVA, ALENA, BOLTE, GABRIELE, BISTRUP, MARIE LOUISE, BUSBY, CHRIS, BUTTER, MAUREEN, DORFMAN, PAUL, FUCIC, ALEKSANDRA, GEE, DAVID, VAN DEN HAZEL, PETER, HOWARD, VYVYAN, KOHLHUBER, MARTINA, LEIJS, MARIKE, LUNDQVIST, CHRISTOFER, MOSHAMMER, HANNS, NAGINIENE, RIMA, NICOLOPOULOU-STAMATI, POLYXENI, RONCHETTI, ROBERTO, SALINES, GEORGES, SCHOETERS, GREET, TUSSCHER, GAVIN TEN, WALLIS, MAX K., and ZUURBIER, MONIEK
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- 2006
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17. Policy and science in childrenʼs health and environment: Recommendations from the PINCHE project
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VAN DEN HAZEL, PETER, ZUURBIER, MONIEK, BISTRUP, MARIE LOUISE, BUSBY, CHRIS, FUCIC, ALEKSANDRA, KOPPE, JANNA G., LUNDQVIST, CHRISTOFER, RONCHETTI, ROBERTO, and TUSSCHER, GAVIN TEN
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- 2006
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18. Cadmium and children: Exposure and health effects
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SCHOETERS, GREET, HOND, ELLY DEN, ZUURBIER, MONIEK, NAGINIENE, RIMA, VAN DEN HAZEL, PETER, STILIANAKIS, NIKOLAOS, RONCHETTI, ROBERTO, and KOPPE, JANNA G.
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- 2006
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19. Air pollution: A threat to the health of our children
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MOSHAMMER, HANNS, BARTONOVA, ALENA, HANKE, WOJTEK, VAN DEN HAZEL, PETER, KOPPE, JANNA G., KRÄMER, URSULA, RONCHETTI, ROBERTO, SRAM, RADIM J., WALLIS, MAX, WALLNER, PETER, and ZUURBIER, MONIEK
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- 2006
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20. Childrenʼs environmental health: Why should social disparities be considered?
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KOHLHUBER, MARTINA, HEINRICH, JOACHIM, VAN DEN HAZEL, PETER, ZUURBIER, MONIEK, BISTRUP, MARIE LOUISE, KOPPE, JANNA G., and BOLTE, GABRIELE
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- 2006
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21. Environmental tobacco smoke exposure and childrenʼs health
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POLANSKA, KINGA, HANKE, WOJCIECH, RONCHETTI, ROBERTO, VAN DEN HAZEL, PETER, ZUURBIER, MONIEK, KOPPE, JANNA G., and BARTONOVA, ALENA
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- 2006
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22. Adverse health effects of childrenʼs exposure to pesticides: What do we really know and what can be done about it
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JUREWICZ, JOANNA, HANKE, WOJCIECH, JOHANSSON, CAROLINA, LUNDQVIST, CHRISTOFER, CECCATELLI, SANDRA, VAN DEN HAZEL, PETER, SAUNDERS, MARGARET, and ZETTERSTRÖM, ROLF
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- 2006
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23. Lead neurotoxicity in children: Is prenatal exposure more important than postnatal exposure?
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RONCHETTI, ROBERTO, VAN DEN HAZEL, PETER, SCHOETERS, GREET, HANKE, WOJTEK, RENNEZOVA, ZUSANA, BARRETO, MARIO, and VILLA, MARIA PIA
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- 2006
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24. Todayʼs epidemics in children: Possible relations to environmental pollution and suggested preventive measures
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Van Den HAZEL, PETER, ZUURBIER, MONIEK, BABISCH, WOLFGANG, BARTONOVA, ALENA, BISTRUP, MARIE LOUISE, BOLTE, GABRIELE, BUSBY, CHRIS, BUTTER, MAUREEN, CECCATELLI, SANDRA, FUCIC, ALEKSANDRA, HANKE, WOJTEC, JOHANSSON, CAROLINA, KOHLHUBER, MARTINA, LEIJS, MARIKE, LUNDQVIST, CHRISTOFER, MOSHAMMER, HANNS, NAGINIENE, RIMA, PREECE, ALAN, RONCHETTI, ROBERTO, SALINES, GEORGES, SAUNDERS, MARGARET, SCHOETERS, GREET, STILIANAKIS, NIKOLAOS, TUSSCHER, GAVIN TEN, and KOPPE, JANNA G.
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- 2006
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25. Policy interpretation network on childrenʼs health and environment
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VAN DEN HAZEL, PETER, ZUURBIER, MONIEK, and BISTRUP, MARIE LOUISE
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- 2006
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26. Environment—lockdown, air pollution and related diseases: could we learn something and make it last?
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Jevtic, Marija, Matkovic, Vlatka, van den Hazel, Peter, and Bouland, Catherine
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CHRONIC disease risk factors ,PREVENTION of chronic diseases ,RESPIRATORY disease prevention ,PREVENTION of heart diseases ,HEART disease risk factors ,RESPIRATORY disease risk factors ,AIR pollution ,COVID-19 ,ENVIRONMENTAL monitoring ,LUNG diseases ,ENVIRONMENTAL health ,STAY-at-home orders ,METROPOLITAN areas ,COVID-19 pandemic ,DISEASE risk factors - Abstract
Although the pandemic has caused substantial losses in economic prosperity and human lives, it has also some positive impacts on the environment. Restricted mobility, complete closure, less traffic and industry have led to improved air quality especially in urban settings. Not only is air pollution an important determinant of chronic diseases, such as heart and lung disorders, but it has also been shown that poor air quality increases the risk of COVID-19. In this article, we review some of the findings on changes in air quality during the pandemic, and its potential effects on health. We need to continue to monitor the effects of change in air quality, due to COVID-19 lockdown or other factors, but also keep all our efforts to improve air quality even faster and more persistent, bringing the pollution levels below what WHO recommends are safe to live with. [ABSTRACT FROM AUTHOR]
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- 2021
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27. COVID-19 and thermoregulation-related problems: Practical recommendations.
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Daanen, Hein, Bose-O'Reilly, Stephan, Brearley, Matt, Flouris, D. Andreas, Gerrett, Nicola M., Huynen, Maud, Jones, Hunter M., Lee, Jason Kai Wei, Morris, Nathan, Norton, Ian, Nybo, Lars, Oppermann, Elspeth, Shumake-Guillemot, Joy, and Van den Hazel, Peter
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COVID-19 pandemic ,BODY temperature regulation ,PHYSIOLOGICAL effects of heat ,PERSONAL protective equipment ,SAFETY appliances - Abstract
The COVID-19 pandemic started in the cold months of the year 2020 in the Northern hemisphere. Concerns were raised that the hot season may lead to additional problems as some typical interventions to prevent heat-related illness could potentially conflict with precautions to reduce coronavirus transmission. Therefore, an international research team organized by the Global Health Heat Information Network generated an inventory of the specific concerns about this nexus and began to address the issues. Three key thermal and covid-19 related topics were highlighted: 1) For the general public, going to public cool areas in the hot season interferes with the recommendation to stay at home to reduce the spread of the virus. Conflicting advice makes it necessary to revise national heat plans and alert policymakers of this forecasted issue. 2) For medical personnel working in hot conditions, heat strain is exacerbated due to a reduction in heat loss from wearing personal protective equipment to prevent contamination. To avoid heat-related injuries, medical personnel are recommended to precool and to minimize the increase in body core temperature using adopted work/rest schedules, specific clothing systems, and by drinking cold fluids. 3) Fever, one of the main symptoms of COVID-19, may be difficult to distinguish from heat-induced hyperthermia and a resting period may be necessary prior to measurement to avoid misinterpretation. In summary, heat in combination with the COVID-19 pandemic leads to additional problems; the impact of which can be reduced by revising heat plans and implementing special measures attentive to these compound risks. [ABSTRACT FROM AUTHOR]
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- 2021
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28. The Human Early-Life Exposome (HELIX): project rationale and design
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Vrijheid, Martine, Slama, Remy, Robinson, Oliver, Chatzi, Leda, Coen, Muireann, van den Hazel, Peter, Thomsen, Cathrine, Wright, John, Athersuch, Toby J., Avellana, Narcis, Basagana, Xavier, Brochot, Celine, Bucchini, Luca, Bustamante, Mariona, Carracedo, Angel, Casas, Maribel, Estivill, Xavier, Fairley, Lesley, van Gent, Diana, Gonzalez, Juan R., Granum, Berit, Grazuleviciene, Regina, Gutzkow, Kristine B., Julvez, Jordi, Keun, Hector C., Kogevinas, Manolis, McEachan, Rosemary R. C., Meltzer, Helle Margrete, Sabido, Eduard, Schwarze, Per E., Siroux, Valerie, Sunyer, Jordi, Want, Elizabeth J., Zeman, Florence, and Nieuwenhuijsen, Mark J.
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Genomes -- Research ,Children -- Health aspects ,Environmental quality -- Health aspects -- Research ,Biological markers -- Physiological aspects -- Research ,Environmental issues ,Health - Abstract
BACKGROUND: Developmental periods in early life may be particularly vulnerable to impacts of environmental exposures. Human research on this topic has generally focused on single exposure-health effect relationships. The 'exposome' concept encompasses the totality of exposures from conception onward, complementing the genome. OBJECTIVES: The Human Early-Life Exposome (HELIX) project is a new collaborative research project that aims to implement novel exposure assessment and biomarker methods to characterize early-life exposure to multiple environmental factors and associate these with omics biomarkers and child health outcomes, thus characterizing the 'early-life exposome.' Here we describe the general design of the project. METHODS: In six existing birth cohort studies in Europe, HELIX will estimate prenatal and postnatal exposure to a broad range of chemical and physical exposures. Exposure models will be developed for the full cohorts totaling 32,000 mother-child pairs, and biomarkers will be measured in a subset of 1,200 mother--child pairs. Nested repeat-sampling panel studies (n = 150) will collect data on biomarker variability, use smartphones to assess mobility and physical activity, and perform personal exposure monitoring. Omics techniques will determine molecular profiles (metabolome, proteome, transcriptome, epigenome) associated with exposures. Statistical methods for multiple exposures will provide exposure-response estimates for fetal and child growth, obesity, neurodevelopment, and respiratory outcomes. A health impact assessment exercise will evaluate risks and benefits of combined exposures. CONCLUSIONS: HELIX is one of the first attempts to describe the early-life exposome of European populations and unravel its relation to omics markers and health in childhood. As proof of concept, it will form an important first step toward the life-course exposome. http://dx.doi.org/10.1289/ehp.1307204, Introduction Environmental hazards such as ambient air pollution, environmental tobacco smoke (ETS), noise, pesticides, and radiation may lead to serious, chronic pathologies. The fetus and infant are particularly vulnerable to [...]
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- 2014
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29. Hoe ‘gezond’ is de relatie Milieu en Gezondheid anno 2009 nog?
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van den Hazel, Peter and Jans, Henk
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- 2009
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30. Good Practices rond binnenmilieu en verkeer in Europa
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van Loenhout, Joris and van den Hazel, Peter
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- 2009
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31. Academische werkplaats medische milieukunde
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van den Hazel, Peter
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- 2009
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32. Application of social media in the environment and health professional community.
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Grossberndt, Sonja, van den Hazel, Peter, and Bartonova, Alena
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SOCIAL media , *COMMUNICATION , *GOVERNMENT policy , *HEALTH - Abstract
The purpose of the EU FP6 funded coordination action HENVINET was to create a permanent network of environment and health professionals. The main outcome is a networking portal (http://www.henvinet.eu), based on the concepts of social media to support communication between professional stakeholders in the environment and health fields. Its aim is to enable sharing of relevant information in an innovative and interactive manner to eventually support policy making. A social networking tool is not necessarily a typical platform for communication in the professional context, or between scientists and decision-makers. The aim of this paper is to look upon the use of social media in relevant professional communities in the light of the HENVINET experience, and to reflect on the acceptance and usefulness of such a new approach. The portal was designed over the course of HENVINET through intensive interactions by a multi-disciplinary group, involving environmental as well as health scientists, but with only limited access to decision-makers' opinions. After the social networking portal was launched, a recruitment campaign was run during the last six months of the project, taking every opportunity to present the portal and to get feedback from users. This feedback was used to improve the functionalities of the tool. Additionally, a feedback session was organized at the final event of the project, attended by over 50 professionals, about half of whom participated from the beginning in the entire HENVINET project. We have also compared the HENVINET portal with similar tools employed by other related communities, and made a literature-based survey on the use of social media for scientific communication. At the end of the project, the portal had more than 300 members with registered professional profile, over 10 topics and 15 discussion groups. The HENVINET consortium members were the most active group of users. The quality of the portal content was considered more important than having a large amount of information. To maintain the content, the majority of the participants declared their willingness to use their time, stating however that dedicated content providers would be also necessary. In theory, professionals see the value of such a tool, and are willing to contribute. Only time will tell if the tool is viable in the long run. [ABSTRACT FROM AUTHOR]
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- 2012
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33. A healthy turn in urban climate change policies; European city workshop proposes health indicators as policy integrators.
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Keune, Hans, Ludlow, David, van den Hazel, Peter, Randall, Scott, and Bartonova, Alena
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CLIMATE change laws ,PUBLIC health ,ADULT education workshops - Abstract
Background: The EU FP6 HENVINET project reviewed the potential relevance of a focus on climate change related health effects for climate change policies at the city region level. This was undertaken by means of a workshop with both scientists, city representatives from several EU-countries, representatives of EU city networks and EUexperts. In this paper we introduce some important health related climate change issues, and discuss the current city policies of the participating cities. Methods: The workshop used a backcasting format to analyse the future relevance of a health perspective, and the main benefits and challenges this would bring to urban policy making. Results: It was concluded that health issues have an important function as indicators of success for urban climate change policies, given the extent to which climate change policies contribute to public health and as such to quality of life. Simultaneously the health perspective may function as a policy integrator in that it can combine several related policy objectives, such as environmental policies, health policies, urban planning and economic development policies, in one framework for action. Furthermore, the participants to the workshop considered public health to be of strategic importance in organizing public support for climate change policies. One important conclusion of the workshop was the view that the connection of science and policy at the city level is inadequate, and that the integration of scientific knowledge on climate change related health effects and local policy practice is in need of more attention. In conclusion, the workshop was viewed as a constructive advance in the process of integration which hopefully will lead to ongoing cooperation. Conclusions: The workshop had the ambition to bring together a diversity of actor perspectives for exchange of knowledge and experiences, and joint understanding as a basis for future cooperation. Next to the complementarities in experience and knowledge, the mutual critical reflection was a bonus, as ideas had the opportunity to be scrutinized by others, leading to more robustness and common ground. The structured backcasting approach was helpful in integrating all of this with one common focus, embracing diversity and complexity, and stimulating reflection and new ideas. [ABSTRACT FROM AUTHOR]
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- 2012
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34. Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives
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Grandjean, Philippe, Barouki, Robert, Bellinger, David C, Casteleyn, Ludwine, Chadwick, Lisa H., Cordier, Sylvaine, Etzel, Ruth A., Gray, Kimberly A., Ha, Eun-Hee, Junien, Claudine, Karagas, Margaret, Kawamoto, Toshihiro, Paige Lawrence, B., Perera, Frederica P., Prins, Gail S., Puga, Alvaro, Rosenfeld, Cheryl S., Sherr, David H., Sly, Peter D., Suk, William, Sun, Qi, Toppari, Jorma, van den Hazel, Peter, Walker, Cheryl L., and Heindel, Jerrold J.
- Abstract
The Developmental Origins of Health and Disease (DOHaD) paradigm is one of the most rapidly expanding areas of biomedical research. Environmental stressors that can impact on DOHaD encompass a variety of environmental and occupational hazards as well as deficiency and oversupply of nutrients and energy. They can disrupt early developmental processes and lead to increased susceptibility to disease/dysfunctions later in life. Presentations at the fourth Conference on Prenatal Programming and Toxicity in Boston, in October 2014, provided important insights and led to new recommendations for research and public health action. The conference highlighted vulnerable exposure windows that can occur as early as the preconception period and epigenetics as a major mechanism than can lead to disadvantageous “reprogramming” of the genome, thereby potentially resulting in transgenerational effects. Stem cells can also be targets of environmental stressors, thus paving another way for effects that may last a lifetime. Current testing paradigms do not allow proper characterization of risk factors and their interactions. Thus, relevant exposure levels and combinations for testing must be identified from human exposure situations and outcome assessments. Testing of potential underpinning mechanisms and biomarker development require laboratory animal models and in vitro approaches. Only few large-scale birth cohorts exist, and collaboration between birth cohorts on a global scale should be facilitated. DOHaD-based research has a crucial role in establishing factors leading to detrimental outcomes and developing early preventative/remediation strategies to combat these risks. The Developmental Origins of Health and Disease (DOHaD) paradigm is one of the most rapidly expanding areas of biomedical research today. This field originated with early observations that malnutrition and low-level exposures to drugs and toxic substances (eg, alcohol and methylmercury) might be well tolerated by a pregnant woman, but her gestating fetus would be afflicted by adverse effects, some of which might become apparent only later in life (1, 2). The field has now broadened to encompass consideration of a variety of environmental and occupational hazards, whether chemical, physical, or biological, and both deficiency and oversupply of nutrients and energy. When these environmental stressors disrupt early developmental processes they may cause changes in cellular gene expression, cell numbers or location of cells that persist and then lead to increased susceptibility to disease/dysfunctions later in life. The fourth Conference on Prenatal Programming and Toxicity (PPTOX IV) in Boston, October, 2014, brought together researchers interested in understanding the role of environmental stressors in developmental programming. As before (3, 4), the goal of the conference was to stimulate and exchange research results and to discuss their implications and how to further develop and strengthen research in this field. This article presents a brief summary of important insights and recommendations that emerged from the conference presentations and discussion sessions. Figure 1 outlines the major issues discussed. Abstracts and presentations are available at the conference web site (http://www.endocrine.org/meetings/pptox-iv). - See more at: http://press.endocrine.org/doi/10.1210/EN.2015-1350#sthash.ocQ8rPcQ.dpuf
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- 2015
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35. The Health and Environment Network and its achievements.
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Bartonova, Alena, Koppe, Janna G., Fucic, Aleksandra, Gutleb, Arno C., van den Hazel, Peter, and Keune, Hans
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ENVIRONMENTAL protection program administration ,HEALTH risk assessment ,ENVIRONMENTAL health ,STAKEHOLDERS ,CLIMATOLOGY - Abstract
The article offers information on the Health and Environment Network (HENVINET) program in the European Union (EU). It notes that the environmental health is a developing field of great social importance. It mentions that the HENVINET is intended to create an integrated network to connect experts, stakeholders and policymakers addressing the social, environmental and climate influences on human health.
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- 2012
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36. P-171.
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Dadvand, Payam, Gidlow, Christopher, Kruize, Hanneke, Grazuleviciene, Regina, Lawrence, Roderick, Maas, Jolanda, van den Hazel, Peter Jan, Seto, Edmund, and Nieuwenhuijsen, Mark
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- 2012
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37. Respiratory Health Effects of Commuters.
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Zuurbier, Moniek, Hoek, Gerard, Oldenwening, Marieke, Meliefste, Kees, Van den Hazel, Peter, and Brunekreef, Bert
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- 2011
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38. Acute Health Effects of Commuters’ Exposure to Air Pollution.
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Zuurbier, Moniek, Hoek, Gerard, Oldenwening, Marieke, Meliefste, Kees, Van den Hazel, Peter, and Brunekreef, Bert
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- 2009
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39. Commuters’ Air Pollution Exposure Is Affected by Vehicle and Fuel Type.
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Zuurbier, Moniek, Hoek, Gerard, Oldenwening, Marieke, Meliefste, Kees, Van den Hazel, Peter, and Brunekreef, Bert
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- 2009
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40. Steps forward reduction of environmental impact on children’s health.
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Grimalt, Joan O., Böse-O’Reilly, Stephan, and van den Hazel, Peter
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- *
CHILDREN'S health , *ENVIRONMENTAL health , *METABOLISM in children , *AIR pollution , *HEALTH , *METHYLMERCURY & the environment - Published
- 2018
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41. The relationship between natural outdoor environments and cognitive functioning and its mediators.
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Zijlema, Wilma L., Triguero-Mas, Margarita, Smith, Graham, Cirach, Marta, Martinez, David, Dadvand, Payam, Gascon, Mireia, Jones, Marc, Gidlow, Christopher, Hurst, Gemma, Masterson, Daniel, Ellis, Naomi, van den Berg, Magdalena, Maas, Jolanda, van Kamp, Irene, van den Hazel, Peter, Kruize, Hanneke, Nieuwenhuijsen, Mark J., and Julvez, Jordi
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- *
COGNITIVE ability , *MEDIATION (Statistics) , *EPIDEMIOLOGY , *BUILT environment , *SOCIAL interaction - Abstract
Background Urban residents may experience cognitive fatigue and little opportunity for mental restoration due to a lack of access to nature. Natural outdoor environments (NOE) are thought to be beneficial for cognitive functioning, but underlying mechanisms are not clear. Objectives To investigate the long-term association between NOE and cognitive function, and its potential mediators. Methods This cross-sectional study was based on adult participants of the Positive Health Effects of the Natural Outdoor Environment in Typical Populations in Different Regions in Europe (PHENOTYPE) project. Data were collected in Barcelona, Spain; Doetinchem, the Netherlands; and Stoke-on-Trent, United Kingdom. We assessed residential distance to NOE, residential surrounding greenness, perceived amount of neighborhood NOE, and engagement with NOE. Cognitive function was assessed with the Color Trails Test (CTT). Mediation analysis was undertaken following Baron and Kenny. Results Each 100 m increase in residential distance to NOE was associated with a longer CTT completion time of 1.50% (95% CI 0.13, 2.89). No associations were found for other NOE indicators and cognitive function. Neighborhood social cohesion was (marginally) significantly associated with both residential distance to NOE and CTT completion time, but no evidence for mediation was found. Nor were there indications for mediation by physical activity, social interaction with neighbors, loneliness, mental health, air pollution worries, or noise annoyance. Conclusions Our findings provide some indication that proximity to nature may benefit cognitive function. We could not establish which mechanisms may explain this relationship. [ABSTRACT FROM AUTHOR]
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- 2017
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42. COVID-19 and heat waves: New challenges for healthcare systems.
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Bose-O'Reilly, Stephan, Daanen, Hein, Deering, Katharina, Gerrett, Nicola, Huynen, Maud Maria Theresia Elisabeth, Lee, Jason, Karrasch, Stefan, Matthies-Wiesler, Franziska, Mertes, Hanna, Schoierer, Julia, Shumake-Guillemot, Joy, van den Hazel, Peter, Frank van Loenhout, Joris Adriaan, and Nowak, Dennis
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- *
COVID-19 , *MEDICAL personnel , *HEAT waves (Meteorology) , *HEALTH facilities , *SARS-CoV-2 , *PERSONAL protective equipment - Abstract
Heat waves and Covid-19 overlap, as this pandemic continues into summer 2021. Using a narrative review, we identified overlapping risk groups and propose coping strategies. The high-risk groups for heat-related health problems as well as for high-risk COVID-19 groups overlap considerably (elderly with pre-existing health conditions). Health care facilities will again be challenged by Covid-19 during heat waves. Health care personnel are also at risk of developing heat related health problems during hot periods due to the use of personal protective equipment to shield themselves from SARS-CoV-2 and must therefore be protected from excessive heat periods. Some existing recommendations for heat health protection contradict recommendations for COVID-19 protection. This paper provides a preliminary overview of possible strategies and interventions to tackle these ambiguities. The existing recommendations for protection against heat-related illnesses need revisions to determine whether they include essential aspects of infection control and occupational safety and how they may be supplemented. • Hot days and heat waves due to climate change are on the rise. • SARS-CoV-2 AND heat stress cause illnesses and fatalities. • Vulnerable groups are old and chronically ill people. • Recommendations to protect them against heat AND SARS-CoV-2 need to be adapted. • Adjusted heat health action plans need to be monitored and evaluated for effectiveness and lessons learnt. [ABSTRACT FROM AUTHOR]
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- 2021
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43. Early environmental quality and life-course mental health effects: The Equal-Life project.
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van Kamp I, Persson Waye K, Kanninen K, Gulliver J, Bozzon A, Psyllidis A, Boshuizen H, Selander J, van den Hazel P, Brambilla M, Foraster M, Julvez J, Klatte M, Jeram S, Lercher P, Botteldooren D, Ristovska G, Kaprio J, Schreckenberg D, Hornikx M, Fels J, Weber M, Braat-Eggen E, Hartmann J, Clark C, Vrijkotte T, Brown L, and Bolte G
- Abstract
Background: There is increasing evidence that a complex interplay of factors within environments in which children grows up, contributes to children's suboptimal mental health and cognitive development. The concept of the life-course exposome helps to study the impact of the physical and social environment, including social inequities, on cognitive development and mental health over time., Methods: Equal-Life develops and tests combined exposures and their effects on children's mental health and cognitive development. Data from eight birth-cohorts and three school studies (N = 240.000) linked to exposure data, will provide insights and policy guidance into aspects of physical and social exposures hitherto untapped, at different scale levels and timeframes, while accounting for social inequities. Reasoning from the outcome point of view, relevant stakeholders participate in the formulation and validation of research questions, and in the formulation of environmental hazards. Exposure assessment combines GIS-based environmental indicators with omics approaches and new data sources, forming the early-life exposome. Statistical tools integrate data at different spatial and temporal granularity and combine exploratory machine learning models with hypothesis-driven causal modeling., Conclusions: Equal-Life contributes to the development and utilization of the exposome concept by (1) integrating the internal, physical and social exposomes, (2) studying a distinct set of life-course effects on a child's development and mental health (3) characterizing the child's environment at different developmental stages and in different activity spaces, (4) looking at supportive environments for child development, rather than merely pollutants, and (5) combining physical, social indicators with novel effect markers and using new data sources describing child activity patterns and environments., Competing Interests: The authors declare that they have no conflicts of interest with regard to the content of this report., (Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The Environmental Epidemiology. All rights reserved.)
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- 2021
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44. [The impact of climate change on health in the Netherlands: the latest insights].
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Quarsie J, van de Pas R, Fanoy E, and van den Hazel P
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- Allergens, Climate Change, Humans, Netherlands epidemiology, Air Pollution, Hypersensitivity
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This synthesis provides the latest insights into the impact of climate change in the Netherlands for which five separate health effects are particularly relevant. Climate change is associated with increased frequency, intensity and duration of heat waves. Major heat-related health risks include heat stroke, exacerbations of renal dysfunction due to dehydration and cardiovascular disease due to overheating. Climate change is associated with more hours of sunshine and more ultraviolet (UV) radiation. Heat and air pollution, both effects of climate change, lead to significant cardiovascular morbidity and mortality. Climate change is associated with an increase in water, food and vector-related infectious diseases due to, among other things, an increased temperature, increased water recreation and an altered water quality. Another effect is an increase in allergies and respiratory complaints via the prolongation and intensification of the pollen season. Our conclusion is that climate change in the Netherlands mainly entails negative health effects.
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- 2021
45. On the importance of primary and community healthcare in relation to global health and environmental threats: lessons from the COVID-19 crisis.
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Lauriola P, Martín-Olmedo P, Leonardi GS, Bouland C, Verheij R, Dückers MLA, van Tongeren M, Laghi F, van den Hazel P, Gokdemir O, Segredo E, Etzel RA, Abelsohn A, Bianchi F, Romizi R, Miserotti G, Romizi F, Bortolotti P, Vinci E, Giustetto G, Santamaria M, Serafini A, Pegoraro S, Agius R, and Zeka A
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- Climate Change, Education, Global Health, Humans, Politics, SARS-CoV-2, Socioeconomic Factors, COVID-19 epidemiology, Community Health Services, Public Health
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In the course of the COVID-19 pandemic, it has become clear that primary healthcare systems play a critical role in clinical care, such as patient screening, triage, physical and psychological support and also in promoting good community advice and awareness in coordination with secondary healthcare and preventive care. Because of the role of social and environmental factors in COVID-19 transmission and burden of disease, it is essential to ensure that there is adequate coordination of population-based health services and public health interventions. The COVID-19 pandemic has shown the primary and community healthcare (P&CHC) system's weaknesses worldwide. In many instances, P&CHC played only a minor role, the emphasis being on hospital and intensive care beds. This was compounded by political failures, in supporting local community resilience. Placing community building, social cohesion and resilience at the forefront of dealing with the COVID-19 crisis can help align solutions that provide a vision of 'planetary health'. This can be achieved by involving local well-being and participation in the face of any pervasive health and environmental crisis, including other epidemics and large-scale ecological crises. This paper proposes that P&CHC should take on two critical roles: first, to support local problem-solving efforts and to serve as a partner in innovative approaches to safeguarding community well-being; and second, to understand the local environment and health risks in the context of the global health perspective. We see this as an opportunity of immediate value and broad consequence beyond the control of the COVID-19 pandemic., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2021
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46. COVID-19 and thermoregulation-related problems: Practical recommendations.
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Daanen H, Bose-O'Reilly S, Brearley M, Flouris DA, Gerrett NM, Huynen M, Jones HM, Lee JKW, Morris N, Norton I, Nybo L, Oppermann E, Shumake-Guillemot J, and Van den Hazel P
- Abstract
The COVID-19 pandemic started in the cold months of the year 2020 in the Northern hemisphere. Concerns were raised that the hot season may lead to additional problems as some typical interventions to prevent heat-related illness could potentially conflict with precautions to reduce coronavirus transmission. Therefore, an international research team organized by the Global Health Heat Information Network generated an inventory of the specific concerns about this nexus and began to address the issues. Three key thermal and covid-19 related topics were highlighted: 1) For the general public, going to public cool areas in the hot season interferes with the recommendation to stay at home to reduce the spread of the virus. Conflicting advice makes it necessary to revise national heat plans and alert policymakers of this forecasted issue. 2) For medical personnel working in hot conditions, heat strain is exacerbated due to a reduction in heat loss from wearing personal protective equipment to prevent contamination. To avoid heat-related injuries, medical personnel are recommended to precool and to minimize the increase in body core temperature using adopted work/rest schedules, specific clothing systems, and by drinking cold fluids. 3) Fever, one of the main symptoms of COVID-19, may be difficult to distinguish from heat-induced hyperthermia and a resting period may be necessary prior to measurement to avoid misinterpretation. In summary, heat in combination with the COVID-19 pandemic leads to additional problems; the impact of which can be reduced by revising heat plans and implementing special measures attentive to these compound risks., Competing Interests: No potential conflict of interest was reported by the authors., (© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.)
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- 2020
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47. Exploring mechanisms underlying the relationship between the natural outdoor environment and health and well-being - Results from the PHENOTYPE project.
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Kruize H, van Kamp I, van den Berg M, van Kempen E, Wendel-Vos W, Ruijsbroek A, Swart W, Maas J, Gidlow C, Smith G, Ellis N, Hurst G, Masterson D, Triguero-Mas M, Cirach M, Gražulevičienė R, van den Hazel P, and Nieuwenhuijsen M
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- Cities, Cross-Sectional Studies, Phenotype, Residence Characteristics, Environment, Mental Health
- Abstract
Background: Despite the large number of studies on beneficial effects of the natural outdoor environment (NOE) on health, the underlying mechanisms are not fully understood., Objective: This study explored the relations between amount, quality, use and experience of the NOE; and physical activity, social contacts and mental well-being., Methods: In this cross-sectional study, data on GIS-derived measures of residential surrounding greenness (NDVI), NOE within 300 m, and audit data on quality of the streetscape were combined with questionnaire data from 3947 adults in four European cities. These included time spent in NOE (use); and perceived greenness, and satisfaction with and importance given to the NOE (experience). Physical activity, social contacts and mental health were selected as key outcome indicators. Descriptive and multilevel analyses were conducted both on pooled data and for individual cities., Results: More minutes spent in the NOE were associated with more minutes of physical activity, a higher frequency of social contacts with neighbors, and better mental well-being. Perceived greenness, satisfaction with and importance of the NOE, were other strong predictors of the outcomes, while GIS measures of NOE and streetscape quality were not. We found clear differences between the four cities., Conclusions: Use and experience of the natural outdoor environment are important predictors for beneficial effects of the natural outdoor environment and health. Future research should focus more on these aspects to further increase our understanding of these mechanisms, and needs to take the local context into account., (Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2020
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48. Human Early Life Exposome (HELIX) study: a European population-based exposome cohort.
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Maitre L, de Bont J, Casas M, Robinson O, Aasvang GM, Agier L, Andrušaitytė S, Ballester F, Basagaña X, Borràs E, Brochot C, Bustamante M, Carracedo A, de Castro M, Dedele A, Donaire-Gonzalez D, Estivill X, Evandt J, Fossati S, Giorgis-Allemand L, R Gonzalez J, Granum B, Grazuleviciene R, Bjerve Gützkow K, Småstuen Haug L, Hernandez-Ferrer C, Heude B, Ibarluzea J, Julvez J, Karachaliou M, Keun HC, Hjertager Krog N, Lau CE, Leventakou V, Lyon-Caen S, Manzano C, Mason D, McEachan R, Meltzer HM, Petraviciene I, Quentin J, Roumeliotaki T, Sabido E, Saulnier PJ, Siskos AP, Siroux V, Sunyer J, Tamayo I, Urquiza J, Vafeiadi M, van Gent D, Vives-Usano M, Waiblinger D, Warembourg C, Chatzi L, Coen M, van den Hazel P, Nieuwenhuijsen MJ, Slama R, Thomsen C, Wright J, and Vrijheid M
- Subjects
- Adult, Attention Deficit Disorder with Hyperactivity epidemiology, Biomarkers blood, Biomarkers urine, Blood Pressure, Body Composition, Body Weights and Measures, Child, Preschool, DNA Methylation, Europe epidemiology, Female, Food Hypersensitivity epidemiology, Gene-Environment Interaction, Hazardous Substances, Humans, Infant, Infant, Newborn, Male, Metabolome, Pregnancy, Prenatal Exposure Delayed Effects metabolism, Prospective Studies, Proteome, Psychological Tests, Respiratory Function Tests, Smoking epidemiology, Socioeconomic Factors, Transcriptome, Urban Population, Young Adult, Environmental Exposure analysis, Mothers statistics & numerical data, Prenatal Exposure Delayed Effects epidemiology
- Abstract
Purpose: Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and describe multiple environmental exposures during early life (pregnancy and childhood) in a prospective cohort and associate these exposures with molecular omics signatures and child health outcomes. Here, we describe recruitment, measurements available and baseline data of the HELIX study populations., Participants: The HELIX study represents a collaborative project across six established and ongoing longitudinal population-based birth cohort studies in six European countries (France, Greece, Lithuania, Norway, Spain and the UK). HELIX used a multilevel study design with the entire study population totalling 31 472 mother-child pairs, recruited during pregnancy, in the six existing cohorts (first level); a subcohort of 1301 mother-child pairs where biomarkers, omics signatures and child health outcomes were measured at age 6-11 years (second level) and repeat-sampling panel studies with around 150 children and 150 pregnant women aimed at collecting personal exposure data (third level)., Findings to Date: Cohort data include urban environment, hazardous substances and lifestyle-related exposures for women during pregnancy and their offspring from birth until 6-11 years. Common, standardised protocols were used to collect biological samples, measure exposure biomarkers and omics signatures and assess child health across the six cohorts. Baseline data of the cohort show substantial variation in health outcomes and determinants between the six countries, for example, in family affluence levels, tobacco smoking, physical activity, dietary habits and prevalence of childhood obesity, asthma, allergies and attention deficit hyperactivity disorder., Future Plans: HELIX study results will inform on the early life exposome and its association with molecular omics signatures and child health outcomes. Cohort data are accessible for future research involving researchers external to the project., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2018
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49. A healthy turn in urban climate change policies; European city workshop proposes health indicators as policy integrators.
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Keune H, Ludlow D, van den Hazel P, Randall S, and Bartonova A
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- Europe, European Union, Humans, Policy Making, Public Health, Climate Change, Health Policy, Urban Health
- Abstract
Background: The EU FP6 HENVINET project reviewed the potential relevance of a focus on climate change related health effects for climate change policies at the city region level. This was undertaken by means of a workshop with both scientists, city representatives from several EU-countries, representatives of EU city networks and EU-experts. In this paper we introduce some important health related climate change issues, and discuss the current city policies of the participating cities., Methods: The workshop used a backcasting format to analyse the future relevance of a health perspective, and the main benefits and challenges this would bring to urban policy making., Results: It was concluded that health issues have an important function as indicators of success for urban climate change policies, given the extent to which climate change policies contribute to public health and as such to quality of life. Simultaneously the health perspective may function as a policy integrator in that it can combine several related policy objectives, such as environmental policies, health policies, urban planning and economic development policies, in one framework for action. Furthermore, the participants to the workshop considered public health to be of strategic importance in organizing public support for climate change policies. One important conclusion of the workshop was the view that the connection of science and policy at the city level is inadequate, and that the integration of scientific knowledge on climate change related health effects and local policy practice is in need of more attention. In conclusion, the workshop was viewed as a constructive advance in the process of integration which hopefully will lead to ongoing cooperation., Conclusions: The workshop had the ambition to bring together a diversity of actor perspectives for exchange of knowledge and experiences, and joint understanding as a basis for future cooperation. Next to the complementarities in experience and knowledge, the mutual critical reflection was a bonus, as ideas had the opportunity to be scrutinized by others, leading to more robustness and common ground. The structured backcasting approach was helpful in integrating all of this with one common focus, embracing diversity and complexity, and stimulating reflection and new ideas.
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- 2012
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50. The Health and Environment Network and its achievements.
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Bartonova A, Koppe JG, Fucic A, Gutleb AC, van den Hazel P, and Keune H
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- Advisory Committees, Europe, European Union, Guidelines as Topic, Humans, Respiratory System, Environmental Health, Health Policy
- Published
- 2012
- Full Text
- View/download PDF
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