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Understanding the microscopic origin of the superior electromechanical response in relaxor ferroelectrics requires knowledge not only of the atomic-scale formation of polar nanodomains (PNDs) but also the rules governing the arrangements and stimulated response of PNDs over longer distances. Using x-ray coherent nanodiffraction, we show the staggered self-assembly of PNDs into unidirectional mesostructures that we refer to as polar laminates in the relaxor ferroelectric 0.68PbMg1/3Nb2/3O3-0.32PbTiO3 (PMN-0.32PT). We reveal the highly heterogeneous electric-field-driven responses of intra- and interlaminate PNDs and establish their correlation with the local strain and the nature of the PND walls. Our observations highlight the critical role of hierarchical lattice organizations on macroscopic material properties and provide guiding principles for the understanding and design of relaxors and a wide range of quantum and functional materials.

The inorganic perovskite CsPbI3 shows promising photophysical properties for a range of potential optoelectronic applications but is metastable at room temperature. To address this, Br can be alloyed into the X-site to create compositions such as CsPbI2Br that are stable at room temperature but have bandgaps >1.9 eV - severely limiting solar applications. Herein, in an effort to achieve phase stable films with bandgaps

The manipulation and control of nanoscale magnetic spin textures are of rising interest as they are potential foundational units in next-generation computing paradigms. Achieving this requires a quantitative understanding of the spin texture behavior under external stimuli using in situ experiments. Lorentz transmission electron microscopy (LTEM) enables real-space imaging of spin textures at the nanoscale, but quantitative characterization of in situ data is extremely challenging. Here, we present an AI-enabled phase-retrieval method based on integrating a generative deep image prior with an image formation forward model for LTEM. Our approach uses a single out-of-focus image for phase retrieval and achieves significantly higher accuracy and robustness to noise compared to existing methods. Furthermore, our method is capable of isolating sample heterogeneities from magnetic contrast, as shown by application to simulated and experimental data. This approach allows quantitative phase reconstruction of in situ data and can also enable near real-time quantitative magnetic imaging.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal agent for coronavirus disease 2019 (COVID-19). Although vaccines have helped to prevent uncontrolled viral spreading, our understanding of the fundamental biology of SARS-CoV-2 infection remains insufficient, which hinders effective therapeutic development. Here, we found that Apolipoprotein E (ApoE), a lipid binding protein, is hijacked by SARS-CoV-2 for infection. Preincubation of SARS-CoV-2 with a neutralizing antibody specific to ApoE led to inhibition of SARS-CoV-2 infection. The ApoE neutralizing antibody efficiently blocked SARS-CoV-2 infection of human iPSC-derived astrocytes and air-liquid interface organoid models in addition to human ACE2-expressing HEK293T cells and Calu-3 lung cells. ApoE mediates SARS-CoV-2 entry through binding to its cellular receptors such as the low density lipoprotein receptor (LDLR). LDLR knockout or ApoE mutations at the receptor binding domain or an ApoE mimetic peptide reduced SARS-CoV-2 infection. Furthermore, we detected strong membrane LDLR expression on SARS-CoV-2 Spike-positive cells in human lung tissues, whereas no or low ACE2 expression was detected. This study provides a new paradigm for SARS-CoV-2 cellular entry through binding of ApoE on the lipoviral particles to host cell receptor(s). Moreover, this study suggests that ApoE neutralizing antibodies are promising antiviral therapies for COVID-19 by blocking entry of both parental virus and variants of concern.

The frequency regulation capability of wind turbines is insufficient to satisfy the needs of grid frequency regulation. The characteristics of energy storage， such as flexible control， substantial throughput capacity， and rapid response rates， can effectively complement wind turbine limitations. Thereby， these facets advocate for incorporating an integrated wind-and-storage system in the practice of grid frequency control. This paper delves into the principles and control strategies associated with the participation of wind turbines and energy storage in the regulation of power system frequency. It outlines the principles and features of energy storage participating in frequency regulation， as well as models for frequency control and the control strategies. Moreover， the paper scrutinizes the characteristics and effects of different and hybrid energy storage systems. Subsequently， it elucidates the principles of frequency control for wind turbines and various control strategies， classifying the control modes of wind turbines into： variable-pitch control， rotor kinetic energy control， and unified control. In conclusion， the current state of advancements and prospects in this field are summarized and envisioned.

AC submarine cable is an important component in AC transmission system of offshore wind farms. However, the issue of charging current limits its application in offshore wind power with long-distance and large-capacity. Taking HYJQF41-F290/500 kV single-core AC submarine cable as an example, the overvoltage distribution along the cable in different working conditions is analyzed, considering the long-distance and high-voltage transmission. The simulation model of the cable is established and its parameters are corrected firstly. According to the different compensation degrees of the shunt reactor, the capacity of the shunt reactor under the configuration scheme of single-end compensation and two-end compensation calculated out. Finally, based on the single-phase grounding fault, the closing and opening conditions in the high-voltage and long-distance wind farm models, and the distribution law of overvoltage along the submarine cable under different reactive power compensation schemes is tested by simulation. The results show that the maximum overvoltage of submarine cables appears in different positions with different compensation schemes. Based on this, the selection methods for high-voltage submarine cable and overvoltage in insulation level design of substation equipment are given out under different compensation schemes, which have certain guiding significance for engineering practice.