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The MYB transcription factor (TF) superfamily, one of the largest gene superfamilies, regulates a variety of physiological processes in plants. Although many MYB superfamily genes have been identified in plants, the MYB TFs in Chinese jujube ( Ziziphus jujuba Mill.) have not been fully identified and characterized. Additionally, the functions of these genes remain unclear. In total, we identified 171 MYB superfamily genes in jujube and divided them into five subfamilies containing 99 genes of the R2R3-MYB subfamily, 58 genes of the MYB-related subfamily, four genes of the R1R2R3-MYB subfamily, one gene of the 4R-MYB subfamily, and nine genes of the atypical MYB subfamily. The 99 R2R3-MYB genes of jujube were divided into 35 groups, C1-C35, and the 58 MYB-related genes were divided into the following groups: the R-R-type, CCA1-like, I-box-binding-like, TBP-like, CPC-like, and Chinese jujube-specific groups. ZjMYB genes in jujube were well supported by additional highly conserved motifs and exon/intron structures. Most R1 repeats of MYB-related proteins comprised the R2 repeat and had highly conserved EED and EEE residue groups in jujube. Three tandem duplicated gene pairs were found on 12 chromosomes in jujube. According to an expression analysis of 126 ZjMYB genes, MYB-related genes played important roles in jujube development and fruit-related biological processes. The total flavonoid content of jujube fruit decreased as ripening progressed. A total of 93 expressed genes were identified in the RNA-sequencing data from jujube fruit, and 56 ZjMYB members presented significant correlations with total flavonoid contents by correlation analysis. Five pairs of paralogous MYB genes within jujube were composed of nine jujube MYB genes. A total of 14 ZjMYB genes had the same homology to the MYB genes of Arabidopsis and peach, indicating that these 14 MYB genes and their orthologs probably existed before the ancestral divergence of the MYB superfamily. We used a synteny analysis of MYB genes between jujube and Arabidopsis to predict that the functions of the ZjMYBs involve flavonoid/phenylpropanoid metabolism, the light signaling pathway, auxin signal transduction, and responses to various abiotic stresses (cold, drought, and salt stresses). Additionally, we speculate that ZjMYB108 is an important TF involved in the flavonoid metabolic pathway. This comprehensive analysis of MYB superfamily genes in jujube lay a solid foundation for future comprehensive analyses of ZjMYB gene functions., Competing Interests: The authors declare that they have no competing interests.

Objective: This study aimed at investigating and measuring the positional relationship between the long axis of the mandibular anterior teeth and the alveolar bone using cone beam computed tomography (CBCT) to provide reference data for implant treatment., Methods: From the CBCT image database, 150 cases of radiographic data were selected according to the inclusion criteria and then were divided into six groups: males' mandibular central incisors, males' mandibular lateral incisors, males' mandibular canines, females' mandibular central incisors, females' mandibular lateral incisors, and females' mandibular canines. The angle (β) formed by the long axis of the mandibular anterior teeth and the corresponding alveolar bone was measured and recorded. Based on the long axis of alveolar bone, if the teeth incline to the lingual side, the value of the angle (β) was positive; otherwise, the value was negative. The resultant data were analyzed by SPSS 19.0., Results: The β of the mandibular central incisors presented a mean value of 4.77° (range: -8.17°-16.10°) for male subjects and 5.38° (range: -5.63°-12.93°) for female subjects. The β of the mandibular lateral incisors exhibited a mean value of 6.12° (range: -2.87°-
17.57°) for male subjects and 5.81° (range: -7.70°-15.70°) for female subjects. Finally, the β of the mandibular canines presented a mean value of 5.01° (range: -8.13°-17.67°) for male subjects and 6.21° (range: -7.70°-17.87°) for female subjects. The percentages of the β between -10° and 10° of males' mandibular incisors, mandibular lateral incisors, and mandibular canines were 87.34%, 80.67%, and 88.00%, respectively and those of females were 90.67%, 82.66%, and 82.66%, respectively. Whether male or female, the percentages of the β between -10° and 10° of the mandibular anterior teeth were more than 80%. The β that inclined to the lingual was not more than 20° and to the labial did not exceed 10°., Conclusions: The long axis of the mandibular anterior teeth was almost consistent with the long axis of the alveolar bone. Therefore, the positional relationship could be referred to make reasonable implants treatment plan.

Objective: This study aims to analyze the angulation of the maxillary anterior teeth relative to the alveolus to provide reference data for clinicians on the best conditions for implant placement in the esthetic zone., Methods: Numerous cone beam computed tomography (CBCT) images were reviewed and screened. A total of 150 maxillary images were selected by strict adherence to the defined inclusive criteria, with 75 images each from male and female patients (between the ages of 19 and 48 years at the time of CBCT scan). The maxillary anterior teeth were gathered into the following three groups for males and females: upper canines, upper lateral incisors, and upper central incisors. Then, the long axis of each qualified tooth and its corresponding alveolar process were drawn, and the angles formed by these structures were measured. The resultant data were analyzed by SPSS 19.0., Results: The long axis of the maxillary anterior teeth all inclined to the palatal side of the alveolar process. The internal angle (α) formed by the long axis of the maxillary central incisors and the long axis of the alveolar bone presented a mean value of 16.22° (range: 2.50°-28.80°) for male subjects and 15.20° (range: 2.20°-27.20°) for female subjects. The internal angle (α) of the maxillary lateral incisors exhibited a mean value of 17.50° (range: 3.80°-29.50°) for male subjects and 15.99° (range: 4.10°-33.30°) for female subjects. Finally, the internal angle (α) of the maxillary canines presented a mean value of 16.27° (range: 1.00°-31.50°) for male subjects and 15.01° (range: 3.50°-27.40°) for female subjects., Conclusions: The long axis of the maxillary anterior teeth all inclined to the palatal side of the alveolar process. For implant placement, careful preoperative analysis and evaluation with CBCT may be beneficial for avoiding the risk factors and achieving
a high probability of success in the esthetic region.

There are three types of glial cells in Caenorhabditis elegans (C. elegans for short): sheath glia, socket glia and glutamate receptor glia. They are mainly located in four sensory organs including the amphid, the cephalic organ, the outer labial sensilla and the inner labial sensilla. C. elegans glial cells play key roles in dendrite extension, neurite guidance and extension, and are essential for synaptogenesis and maintain the normal morphology and the function of sensory nerve endings as well. A recent study shown that some nematode neurons are derived from the glial cells. Moreover, nematodes glial cells can directly modulate the function of sensory neurons. Some glial cells can also respond to certain external stimuli, such as mechanical stimulation, and adjust the accompanying neuronal activities.The article summarizes the progress on effects of nematodes glial cells on the nervous system development and function.