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In this research, we regard a miniature significant for many cell types and activates stimulants against external interventions, thereby causing calcium oscillation. We stage the dependent variables regarding the Atangana–Balenau derivative operator in terms of Caputo so that the model can be physically interpreted better. The study investigates the existence and uniqueness of solutions using fixed point theory, stability in terms of Hyers–Ulam, positivity and numerical solutions. In addition, spacetime, phase diagrams and three-dimensional graphic simulations are presented due to the Lagrange interpolation technique for parameter selections that match the existence and uniqueness condition of the solution. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Behcet Uz Children's Hospital is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Advanced Research in Health Sciences (JARHS) / Sağlık Bilimlerinde İleri Araştırmalar Dergisi (SABİAD) is the property of Journal of Advanced Research in Health Sciences (JARHS) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Large cell calcifying Sertoli cell tumours (LCCSCTs) are one of the infrequent causes of prepubertal gynaecomastia. Most of these tumours are in the content of Peutz–Jeghers syndrome (PJS) or other familial syndromes (Carney complex). Here, we report a long-term follow-up of an 8.5-year-old prepubertal boy with a diagnosis of PJS, who presented with bilateral gynaecomastia, advanced bone age and accelerated growth velocity, and were found to have bilateral multifocal testicular microcalcifications. As the findings were compatible with LCCSCT, anastrozole was initiated. Gynaecomastia completely regressed and growth velocity and pubertal development were appropriate for age during follow-up. Testicular lesions slightly increased in size. After four years of medication, anastrozole was discontinued but was restarted due to the recurrence of gynaecomastia after six months. Testicular tumour should be investigated in a patient with PJS who presents with prepubertal gynaecomastia. When findings are consistent with LCCSCT, aromatase inhibitors may be preferred in the treatment. [ABSTRACT FROM AUTHOR]

Background. Various studies, mainly conducted in adults, have examined the hormonal axis in primary empty sella (PES), and reported various forms of pituitary deficiencies. We report our experience with PES in pediatric patients in terms of pituitary function, associated impairments, and responses to treatment. Methods. We reviewed 10,560 cranial and 325 pituitary magnetic resonance imagings (MRIs) performed at our university hospital between January 2010 and December 2020 and identified patients with PES. Patients with additional abnormal MRI findings, a history of cranial surgery or radiotherapy, autoimmunity, long-term use of chemotherapeutic or immunosuppressive agents or incomplete diagnostic evaluation were excluded. Clinical, radiological and laboratory evaluations were recorded. Results. The study included 17 patients [9 girls, 8 boys; median age 12.4 years (7.25, 4.3 - 17)]. The median size of the pituitary was 2 mm (0.7, 1.2 - 3). Based on age-dependent pituitary height measurements, fifteen (88%) patients had pituitary gland hypoplasia. Five patients presented with short stature, two had both pubertal delay and short stature, and one had pubertal delay. Nine patients presented with neurological symptoms such as headaches, tinnitus, tics, and dizziness. Five short patients had growth hormone deficiency. None of the patients had hyper- or hypoprolactinemia, adrenal insufficiency, hypothyroidism, or diabetes insipidus. There was statistically no significant association between the size of the pituitary gland and the severity of hypopituitarism (p = 0.42). Conclusions. The high incidence of pituitary dysfunctions ascertain that this entity should not be considered a normal variant but, should instead be carefully evaluated with appropriate basal and dynamic hormonal testing. [ABSTRACT FROM AUTHOR]

Background. CD59 is the principal cell inhibitor of complement membrane attack on cells. Stroke, peripheral neuropathy, and recurrent central nervous system attacks have been reported in patients with inherited CD59 deficiency. In this paper, we report a patient with CD59 deficiency associated with two attacks of demyelinating peripheral neuropathy and the third attack as an isolated optic neuritis. Case. An 8-month-old girl whose sibling died at 12th month of age with recurrent weakness episodes responsive to intravenous immune globulin treatment, presented with weakness in legs and poor sucking. Weakness episodes with neurogenic electromyography suggested CD59 deficiency. Immunophenotypic analysis with flow cytometry showed CD59 deficiency. Sanger sequencing of CD59 gene revealed a homozygous c146delA (p.Asp49Valfs*32) mutation. First two attacks were treated with intravenous immunoglobulin therapy without any sequalae. Third attack was an isolated optic neuritis which could not be explained by any other entity. The patient had no response to intravenous immunoglobulin but benefited from pulse steroid therapy. Eculizumab was started every two weeks in order to prevent possible advanced attacks and to reduce their severity. Conclusion. Although it is a rarely reported disease, better recognition of CD59 deficiency by pediatric neurologists is necessary because it is curable. In addition to different presentations reported, optic neuritis may also be a manifestation of CD59 deficiency. [ABSTRACT FROM AUTHOR]

Background. Recurrent painful ophthalmologic neuropathy (RPON), formerly known as ophthalmoplegic migraine, is characterized by repeated attacks of one or more ocular cranial nerve palsies with an ipsilateral headache. While steroid therapy has been reported to be beneficial for attacks, no clear consensus on prophylactic treatments exists. We present two cases emphasizing the diagnostic significance of the loss of enhancement during the symptom-free period and valproate as a beneficial option in prophylaxis. Case 1. A 4-year-old girl presented with a one-week right frontal headache, vomiting and photophobia. Neurological examination revealed ptosis, oculomotor nerve paresis, and delay in light reflex in the right eye. Brain magnetic resonance imaging (MRI) revealed a 5.5 mm nodular enhancement in the cisternal part of the 3rd cranial nerve in the right premesencephalic area. The enhancement regressed after a 6-month symptom-free period. While propranolol, topiramate and flunarizine were inefficacious in prophylaxis, the patient responded to valproate prophylaxis and benefited from the administration of steroids for one week during the attacks. Case 2. A 7-year-old girl presented with a ten-day right-sided, throbbing headache in the frontal region, one-day eye deviation and double vision. Neurological examination revealed inward gaze restriction and ptosis in the ipsilateral eye to the headache. Brain MRI revealed a 4.5 mm, enhancing, nodular lesion in the 3rd cranial nerve lodge in the right perimesencephalic area. Her symptoms regressed in one week with dexamethasone and she received prophylactic propranolol. Neuroimaging findings disappeared after a 3-month symptom-free period. After valproate was added because of a relapse, she did not experience any further attacks. Conclusions. RPON is an uncommon disease in childhood with unknown etiology. On brain MRI with contrast during the symptom-free period, regression of the enhancement or complete resolution of the lesion are guiding features in the diagnosis. Valproate may have beneficial effects on RPON treatment. [ABSTRACT FROM AUTHOR]

In this paper, we establish some results concerning the convolutions of harmonic mappings convex in the horizontal direction with harmonic vertical strip mappings. Furthermore, we provide examples illustrated graphically with the help of Maple to illuminate the results. [ABSTRACT FROM AUTHOR]

In this paper, we consider a class of normalized harmonic functions in the unit disk satisfying a third-order differential inequality and we investigate several properties of this class such as close-to-convexity, coefficient bounds, growth estimates, sufficient coefficient condition, and convolution. Moreover, as an application, we construct harmonic polynomials involving Gaussian hypergeometric function which belong to the considered class. We also provide examples illustrating graphically with the help of Maple. [ABSTRACT FROM AUTHOR]

The convolution of convex harmonic univalent functions in the unit disk, unlike analytic functions, may not be convex or even univalent. The main purpose of this work is to develop previous work involving the convolution of convex harmonic functions. Briefly, we obtain under which conditions the convolution of a right half-plane harmonic mapping having a dilatation − z and a slanted half-plane harmonic mapping with β having a dilatation e i μ ρ + z 1 + ρ ¯ z | ρ | < 1 and μ ∈ R is univalent and convex in the direction − β. We also provide an example illustrating graphically with the help of Maple to illuminate the result. [ABSTRACT FROM AUTHOR]

The main object of this paper is to investigate the convolution of a subclass of harmonic univalent mappings which is denoted by fa and generalized harmonic univalent mapping which is denoted by Pc. We obtained Pc * fa is univalent and convex in the horizantal direction for 0 < c ≤ .... In addition, we present an example and illustrate it graphically with the help of Maple to explain the behaviour of image domain. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Values Education is the property of Journal of Values Education and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In this work, the dynamics of traveling waves of an improved nonlinear space-time fractional Schrödinger's equation with spatio-temporal dispersion in addition to group-velocity dispersion are studied. This equation models the propagation of solitons through nano optical fibers. The fractional derivative form is considered in the meaning of conformable fractional derivative. The exp(-ɸ(ξ)) algorithm will be carried out for retrieving the optical soliton solutions containing the form of kink and multi-soliton shapes. In addition, some graphical simulations of solutions are provided for better understanding the physical phenomena. [ABSTRACT FROM AUTHOR]

Abstract: This study was aimed to determine the changes of the local anchovy meal which is known as hamsi kaygana in Turkey during cold storage at +4°C ± 1°C. Physicochemical (pH, TVB‐N, TMA‐N, and TBA) shelf life analyses were carried out for hamsi kaygana samples. It was confirmed that the pH values obtained from research groups were within the limit values of the literature. No statistically significant difference was observed (p > .05) between control, stinging nettle, and rosemary groups that were within all created product groups on 12th day of storage, and the observed difference was only present in cumin group (p < .05). Upon examining TVB‐N (Total Volatile Basic Nitrogen) values on 12th day of storage, we saw the lowest TVB‐N value (17.01 ± 0.21 mg/100 g) was at stinging nettle group. However; it was found out that highest TVB‐N value belonged to cumin group with the value of 19.38 ± 0.42 mg/100 g. It was found that 12th day TBA (Thiobarbituric Acid) values of all other groups except control group did not exceed limit values. Among TMA‐N (Trimethylamine Nitrogen) values of all groups on 12th storage period, the lowest value belonged to cumin group samples. While the highest TMA‐N value was found as 14.70 ± 0.30 in control group samples. Therefore, the results showed us that using dried herb and spices in hamsi kaygana production and the storage of the products have an influence on shelf life. [ABSTRACT FROM AUTHOR]

Let SH(α, s, t) be the class of normalized harmonic functions f = h + ... defined in the open unit disk satisfying ... for complex numbers s, t with s ≠ t and for α (0 ≤ α < 1). The main object of this paper is to obtain a necessary and sufficient convolution characterization and a sufficient coefficient condition for the class SH(α s, t). Also, distortion bounds for the function f satisfying the coefficient condition are obtained. [ABSTRACT FROM AUTHOR]

In this paper, we study the ratio of harmonic multivalent functions to its sequences of partial sums. [ABSTRACT FROM AUTHOR]

A p times continuously differentiable complex-valued function F = u + iV in a domain D ⊆ C is p-harmonic if F satisfies the p-harmonic equation Δ ... ΔF = 0, where p is a positive integer. By using the generalized Salagean differential operator, we introduce aclass of p-harmonic functions and investigate necessary and sufficient coefficient conditions, distortion bounds, extreme points, and convex combination of the class. [ABSTRACT FROM AUTHOR]

The main purpose of this paper is to introduce a generalization of modified Salagean operator for harmonic univalent functions. We define a new subclass of complex-valued harmonic univalent functions by using this operator ,and we investigate necessary and sufficient coefficient conditions, distortion bounds, extreme points and convex combination for the above class of harmonic univalent functions. [ABSTRACT FROM AUTHOR]

Jahangiri et al. [5] defined "modified Salagean operator" for harmonic univalent functions in the unit disk. In that study, they also obtained necessary and sufficient coefficient conditions for the Salagean-type class of harmonic univalent functions. By using those coefficient conditions, we investigate some convolution properties for the Salagean-type class of harmonic univalent functions. [ABSTRACT FROM AUTHOR]

Background: Various studies, mainly conducted in adults, have examined the hormonal axis in primary empty sella (PES), and reported various forms of pituitary deficiencies. We report our experience with PES in pediatric patients in terms of pituitary function, associated impairments, and responses to treatment., Methods: We reviewed 10,560 cranial and 325 pituitary magnetic resonance imagings (MRIs) performed at our university hospital between January 2010 and December 2020 and identified patients with PES. Patients with additional abnormal MRI findings, a history of cranial surgery or radiotherapy, autoimmunity, long-term use of chemotherapeutic or immunosuppressive agents or incomplete diagnostic evaluation were excluded. Clinical, radiological and laboratory evaluations were recorded., Results: The study included 17 patients [9 girls, 8 boys; median age 12.4 years (7.25, 4.3 - 17)]. The median size of the pituitary was 2 mm (0.7, 1.2 - 3). Based on age-dependent pituitary height measurements, fifteen (88%) patients had pituitary gland hypoplasia. Five patients presented with short stature, two had both pubertal delay and short stature, and one had pubertal delay. Nine patients presented with neurological symptoms such as headaches, tinnitus, tics, and dizziness. Five short patients had growth hormone deficiency. None of the patients had hyper- or hypoprolactinemia, adrenal insufficiency, hypothyroidism, or diabetes insipidus. There was statistically no significant association between the size of the pituitary gland and the severity of hypopituitarism (p = 0.42)., Conclusions: The high incidence of pituitary dysfunctions ascertain that this entity should not be considered a normal variant but, should instead be carefully evaluated with appropriate basal and dynamic hormonal testing.