Search

Your search keyword '"Xu, Lu"' showing total 4,452 results
Start Over Author "Xu, Lu" Publication Type Academic Journals
4,452 results on '"Xu, Lu"'

15. Epacadostat plus pembrolizumab versus placebo plus pembrolizumab as first-line treatment for metastatic non-small cell lung cancer with high levels of programmed death-ligand 1: a randomized, double-blind phase 2 study

Author

Tokito, Takaaki, Kolesnik, Oleksii, Sørensen, Jens, Artac, Mehmet, Quintela, Martín Lázaro, Lee, Jong-Seok, Hussein, Maen, Pless, Miklos, Paz-Ares, Luis, Leopold, Lance, Daniel, Jeannie, Munteanu, Mihaela, Samkari, Ayman, Xu, Lu, and Butts, Charles

Published
2024
Full Text
View/download PDF

20. Research on live detection technology of distribution network cable insulation deterioration state based on harmonic components

Author

Ran Hu, Haisong Xu, Xu Lu, Anzhe Wang, Zhifeng Xu, Yuli Wang, and Daning Zhang

Subjects
ageing, eddy currents, finite element analysis, harmonic analysis, Distribution or transmission of electric power, TK3001-3521, Production of electric energy or power. Powerplants. Central stations, TK1001-1841
Abstract

Abstract Due to the limitations imposed by urban power grid outages for maintenance, on‐line harmonic current detection technology for distribution network cables is expected to become an effective supplement to traditional offline diagnostic methods, enhancing the real‐time diagnosis of distribution network cable insulation conditions. This study established a 10 kV distribution network cable test platform and prepared typical defective cables subjected to moisture and long‐term thermal aging. Using COMSOL finite element electromagnetic simulation, the magnetic flux evolution laws of the cable insulation under typical defects were obtained. Experimental tests provided the harmonic current characteristics and statistical features of cables with typical defects. Based on these data, a method for analysing the degradation degree of distribution network cables was constructed using least absolute shrinkage and selection operator (LASSO) regression analysis. Furthermore, a defect‐type identification method based on cluster analysis was proposed. Results indicate that the odd harmonics and the 4th harmonic of the distribution network cable's harmonic current are closely related to the cable's degradation state. A model integrating principal component analysis (PCA) data dimensionality reduction and expectation‐maximization clustering analysis achieved a recognition accuracy of up to 75.64% in distinguishing between moisture‐affected and normal cable states. The proposed on‐line detection and evaluation methods can effectively identify high‐risk cables with latent defects.

Published
2024
Full Text
View/download PDF

21. Effects of Different Factors on Yolk Blackening in Salted Duck Egg

Author

SUN Jing, YANG Xue, PENG Xu, LU Lizhi, ZENG Tao, JIA Ming, SHEN Jie, DU Jinping

Subjects
duck eggs, microorganisms, hydrogen sulfide, discoloration reaction, proteomics, Food processing and manufacture, TP368-456
Abstract

In order to analyze the factors affecting yolk blackening in salted duck eggs, this study investigated the differences in the color difference, metal ion contents and proteomics in different parts of normal and black-yolked salted duck eggs. The effects of these factors on the degree and rate of yolk blackening were studied by single factor experiments. The results showed that the higher the contents of Fe and Cu, the smaller the color difference value of yolk and the blacker the color. It was speculated that the sulfide formed by the combination of Fe2+ in phosvitin (Pv) and S2- was responsible for the blackening of egg yolk, and the degradation and desulfurization of cysteine was an important contributor to sulfur production in egg yolk. Microbial load, temperature and pH were important factors affecting yolk blackening. With increasing bacterial load and curing temperature of duck eggs, the rate of yolk blackening increased. H2S was produced in the pH range of 7.0–8.0, and the gas production rate was the fastest at pH 7.5. In summary, it can be inferred that yolk blackening in salted duck eggs is caused by the discoloration reaction between sulfur and iron elements in egg yolk. Curing temperature, pH and the bacterial load of duck eggs have a great influence on yolk blackening.

Published
2024
Full Text
View/download PDF

22. Research Progress on the Metabolites Formation Mechanism of Plant Jiaosu

Author

Yanan ZHOU, Shuyi ZHENG, Jiawen LIU, Yu DONG, and Xu LU

Subjects
plant jiaosu, fermentation, microbial species, metabolic mechanism, flavor substance, Food processing and manufacture, TP368-456
Abstract

Plant Jiaosu is a kind of product made from fruit and vegetable cereals as the main raw material by microbial fermentation. It has been gradually favored by the public because of its non-toxic and harmless characteristics and multiple physiological functions. Understanding the metabolic mechanisms of plant Jiaosu plays an important role in improving their quality. However, there are still few summaries on the metabolic mechanism of plant Jiaosu. This paper comprehensively analyzes the research progress of plant Jiaosu, and introduces the related metabolic pathways, product change analysis, product formation influencing factors, flavor source and flavor substance changes of plant Jiaosu in the process of plant ferment glycolysis. The future development of plant Jiaosu is discussed, which provides a reference for the further research and development of plant Jiaosu.

Published
2024
Full Text
View/download PDF

23. Predictive value of serum magnesium levels for prognosis in patients with non-small cell lung cancer undergoing EGFR-TKI therapy

Author

Xu Fang-Zhou, Meng Fu-Rong, Li Wan-Jing, Xu Lu, Zhang Hao, Zhang Yan-Bei, and Fan Xiao-Yun

Subjects
egfr-tki, magnesium, non-small cell lung cancer, overall survival, progression-free survival, Biology (General), QH301-705.5
Abstract

The aim of this study is to assess the impact of serum magnesium (Mg) levels on prognostic outcomes in patients with non-small cell lung cancer (NSCLC) undergoing treatment with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI). A cohort comprising 91 patients with NSCLC with epidermal growth factor receptor mutations received EGFR-TKI therapy. Assessments of liver and kidney function and electrolyte levels were conducted before treatment initiation and after completing two cycles of EGFR-TKI therapy. Data on variables such as age, gender, presence of distant metastasis, smoking history, other therapeutic interventions, and the specific TKI used were collected for analysis. Cox regression analysis revealed that patients with higher Mg levels prior to EGFR-TKI therapy had significantly longer progression-free survival (PFS) and overall survival (OS). Elevated Mg levels remained predictive of PFS and OS after two cycles of EGFR-TKI therapy. Multiple regression analysis confirmed these findings. Additionally, it was observed that smokers might represent a unique population, demonstrating a correlation between OS and Mg levels. Our findings indicate that serum Mg level is a prognostic factor in patients with NSCLC undergoing EGFR-TKI therapy. This may provide new insights into the underlying mechanisms of EGFR-TKI therapy related to electrolyte balance.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results