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Supercapacitors offer superior cycle life and high power densities, but as energy storage devices, they are limited by self-discharge processes manifested as large potential decay and leakage current, resulting in loss of stored energy and low charging efficiency. To minimize Faradaic side reactions, this Letter has incorporated a sulfonate ion-exchange resin in separators to trap impurities and thereby suppress self-discharge in supercapacitors with PEDOT as redox electrodes. The versatile separator design is generally applicable to organic and aqueous electrolytes and compatible with a pH range of 0-14, while maintaining the device capacitance and rate performance. Temperature-dependent characteristics were analyzed to identify that the reduction of impurity concentration and diffusion was key to improve potential retention. Compared to devices using commercially available separators, the device here exhibited a lower leakage current and better charging efficiency. It was demonstrated to work with radio frequency energy-harvesting circuits and showed the potential to serve as an energy reservoir for wireless electronic applications.

Wound healing is a complex process involving diverse changes in multiple cell types where the application of electric fields has been shown to accelerate wound closure. To define the efficacy of therapies based on electric fields, it would be valuable to have a platform to systematically study the effects of electrical stimulation (ES) upon the inflammation phase and the activation of signaling mediators. Here, an in vivo ES model in which flexible electrodes are applied to an animal model for monitoring inflammation in a wound is reported on. Subcutaneous implants of polyvinyl alcohol sponges elicit inflammation response as defined by the infiltration of leukocytes. The wound site is subjected to electric fields using two types of additively fabricated flexible electrode arrays. The sponges are then harvested for flow cytometry analysis to identify changes in the phosphorylation state of intracellular targets. This platform enables studies of molecular mechanisms, as it shows that an application of low-frequency ES ≤0.5 Hz increases phosphorylation of Erk proteins in recruited leukocytes, identifying a signaling pathway that is activated during the healing process.

In recent years, enterprises have increasingly recognized the pivotal role of external users in driving product innovation. Open innovation platforms (OIPs), which facilitate interactions between companies and external innovators, have emerged as critical conduits in this regard. However, OIP managers face the challenge of motivating innovators to sustain their contributions. While some OIPs have implemented material incentives, the impact of such rewards on users' ongoing innovation efforts remains uncertain. This study utilized a large-scale dataset from an OIP to examine how performance-contingent material rewards influence the subsequent behaviors of online innovators. Employing a quasi-experimental design involving propensity score matching (PSM) and difference-in-differences (DID) analysis, we found that receiving performance-contingent material rewards led to a decrease in the quantity of subsequent ideas generated by innovators. However, these rewarded innovators produced ideas of higher quality. Interestingly, the novelty of ideas submitted by innovators declined following their receiving of rewards. Moreover, newly enlisted innovators exhibited a more positive response to these incentives. Our findings provide valuable insights for platform managers seeking to optimize incentive mechanisms. We suggest adopting diversified incentive approaches and refining incentive strategies to effectively motivate continuous innovation among users on OIPs. [ABSTRACT FROM AUTHOR]

The multichannel concentric-ring electrodes are stencil printed on stretchable elastomers modified to improve adhesion to skin and minimize motion artifacts for electrophysiological recordings of electroencephalography, electromyography, and electrocardiography. These dry electrodes with a poly(3,4-ethylenedioxythiophene) polystyrene sulfonate interface layer are optimized to show lower noise level than that of commercial gel disc electrodes. The concentric ring geometry enables Laplacian filtering to pinpoint the bioelectric potential source with spatial resolution determined by the ring distance. This work shows a new fabrication approach to integrate and create designs that enhance spatial resolution for high-quality electrophysiology monitoring devices.

Rapid urbanization has made mountain development an important means to alleviate the shortages of construction land on plains, which has significantly affected regional ecosystem services. In-depth research on the impact of urbanization on ecosystem services under altitude gradients is of great significance to clarify the relationship between the two. Based on data from 2000, 2010 and 2020, the urbanization level and ecosystem services of the study area were evaluated. The spatial correlation of ecosystem services was analyzed by Moran's I. A spatial Durbin model (SDM) was selected to fit the regression. The results show that (1) from 2000 to 2020, the ecosystem services in the study area displayed obvious regional characteristics and aggregation characteristics; (2) in plain areas, the indirect effects of economic, population and land urbanization have a greater negative impact, and compared with shallow mountain areas, deep mountain areas are more negatively affected by economic urbanization and land urbanization; and (3) the significant difference in regression results reflects the rationality of using the spatial Durbin model, as in this paper, and proves the scientific nature of regional coordinated development. The research results provide a reference for the future coordinated development of regional economies and environments. [ABSTRACT FROM AUTHOR]

Monitoring the temperature to determine the fire source locations is essential for controlling the spontaneous combustion in the goaf. Optical fiber sensors are employed to measure the temperature distribution in the goaf. However, due to changes in the geological conditions and the influence of the falling rocks in the goaf, only sensors on the upper side of the uncompacted goaf, due to inclination and coal pillar, may remain. Unilateral sensors are located on the upper side of the goaf, while fire occurs in the center. To investigate the issue with linear unilateral sensors, a two-dimensional inverse method has been developed to determine the location of fire sources by considering heat transfer after a fire inside the goaf. The equations were theoretically solved using Green's function method to obtain the internal temperature distribution of the physical model of the goaf. Sensitivity analysis identified the most crucial parameters in the process of spontaneous heating at different temperature. The fire source location can be determined using a loop method based on the model calculations. We considered a case to validate the model. Accurately identifying the fire source location in the goaf using the unilateral sensors has an essential theoretical and practical significance for fire prevention and fighting. [ABSTRACT FROM AUTHOR]

Angelica sinensis polysaccharide (ASP) showed increasingly recognized hepatoprotective effects and lipid regulation. Because polysaccharides are typically degraded into fragments or short‐chain fatty acids in the gut, rather than being absorbed in their intact form, it is worth pondering why ASP can regulate hepatic lipid metabolism and protect the liver from damage caused by lipid accumulation. In vivo and in vitro nonalcoholic fatty liver disease (NAFLD) models with lipid accumulation were established to investigate the effect and potential mechanisms of ASP on hepatic fat accumulation. Our results showed that ASP remodeled the composition and abundance of the gut microbiota in high‐fat diet‐fed mice and increased their levels of propionate (0.92 ± 0.30 × 107 vs. 2.13 ± 0.52 × 107) and butyrate (1.83 ± 1.31 × 107 vs. 6.39 ± 1.44 × 107). Sodium propionate significantly increased the expression of estrogen‐related receptor α (ERRα) in liver cells (400 mM sodium propionate for 2.19‐fold increase) and alleviated the progress of NAFLD in methionine–choline‐deficient diet model. Taken together, our study demonstrated that ASP can regulate hepatic lipid metabolism via propionate/ERRα pathway and ultimately relieving NAFLD. Our findings demonstrate that ASP can be used as a health care product or food supplement to prevent NAFLD. [ABSTRACT FROM AUTHOR]