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Sebaceous differentiation in salivary gland tissue is common. However, sebaceous neoplasms within the salivary glands are rare. We present the case of a sebaceous lymphadenoma with unusual features, arising in the parotid gland of a 60-year-old male. To the best of our knowledge, this is the first report of the ultrasound and MRI characteristics of this rare tumour. The difficulties encountered in reaching a definitive diagnosis both radiologically and histologically are described.

Objective: The resin monomer triethyleneglycoldimethacrylate (TEGDMA) is used as a diluent in many resin-based bonding, cementing and direct tooth filling materials., Methods: In the present study the uptake and the clearance of 14C-TEGDMA applied via different routes were examined in vivo in guinea pigs. TEGDMA (0.02 mmol/kg by weight labeled with a tracer dose 14C-TEGDMA 0.7Bq/g by weight) was administered by gastric tube or by subcutaneous injection. Urine, feces, and exhaled carbon dioxide were collected for 24h after administration. The animals were killed 24h after the beginning of the experiment and various organs removed and 14C-radioactivity measured., Results: It was apparent that 14C-TEGDMA was taken up rapidly from the stomach and small intestine after gastric administration and was widely distributed in the body following administration by each of the routes. Clearance from most tissues following gastric and intradermal administration was essentially complete within one day. Low fecal 14C-levels (<1% of the administered dose) and urinary levels of about 15% after 24h were noted with each route of administration. Direct measurement of exhaled carbon dioxide showed that 60-65% of the administered dose of 14C left the body via the lungs during 24h. It is likely that 14C-pyruvate is formed in vivo resulting possibly in the formation of toxic 14C-TEGDMA-intermediates., Significance: Despite using a high administered dose, the peak TEGDMA levels in all tissues examined after 24h were at least 100,000-fold less than known toxic levels.

As a preliminary to the revision of the Griffiths scales, 79 examiners throughout Britain tested 447 infants under the age of 2 years during 1978-1982. Compared with the original standardization sample of 1947-1951, the 1980 sample mean general quotient (GQ) was significantly higher, even after adjustments had been made for a slightly skewed social class distribution. Nor did regional differences between samples account for the GQ differences. Unreliable items were not significantly more common among those where the median age at passing had changed most. Various technical difficulties in representing differences between samples were encountered and dealt with. A population's overall results may be given in terms of mean score increase per month, median age advance in weeks or months, e.g. per year, and increase in general developmental quotient. Findings of differences between populations in age at passing individual items can be given as advances in median age, but are better expressed as ratios of the median ages of the two samples in order to deal with the differences in the chronological age for which items are designed. Only then can items be compared for amount of change. In terms of score and mental age advances the second year appears more changed than the first, but in terms of GQ the reverse is true. The locomotor scale mean differs more than other scales from the original norms for both years of infancy, while the personal-social scale differs more in the first year. Taking the most cautious estimate of differences from the data available on both samples, at least 160 items are now passed earlier than in the 1950 sample and the ratio of 1950 to 1980 ages is greater than 110 for 83 of those. Further study of the Griffiths scales items, in relation to one another and to cultural factors, seems feasible on the basis of steps illustrated in this paper.

Six videotapes covering 1406 administrations of items from the Griffiths Scales of Mental Development were made, and each one was shown to a different panel of 9 or 10 observers. Each person independently scored the items and made comments on administration and scoring. Reasons for disagreements among scorers were considered in terms of these comments and the characteristics of individuals and groups participating. Disagreement was particularly high for items from the Baby Scales. This was at least partly due to use of mothers' reports. Mothers' reports were found to present a particular problem when elicited on occasions for which they are not recommended by the manual. Across all ages disagreement was related to difficulties with both administrative and scoring criteria. The present study was designed to be sensitive to a range of sources of unreliability and the findings may have relevance for other infant assessment procedures.