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Your search keyword '"Venessa T. Chin"' showing total 1 results
Start Over Author "Venessa T. Chin" Publication Type Academic Journals
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1. Effective modulation of stromal signaling through ROCK inhibition: Is it all in the timing?

Author

Venessa T. Chin, Claire Vennin, Paul Timpson, and Marina Pajic

Subjects
extracellular matrix, pancreatic cancer, rho gtpase, rock inhibitors, tailored therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Our recent publication demonstrates that transient inhibition of Rho-associated kinase signaling within stroma, significantly decreased in vivo primary tumor growth, metastasis and improved response to standard-of-care therapy in pancreatic cancer. Automated analysis of collagen organization in patient tumors may present a promising tool to predict response to our proposed treatment.

Published
2017
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