569 results on '"Thorens, Bernard"'
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2. GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion
3. Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia
4. Correction: Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes
5. Correction: Cold-induced dishabituation in rodents exposed to recurrent hypoglycaemia
6. The glucose transporter 2 regulates CD8+ T cell function via environment sensing
7. Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes
8. Identification of biomarkers for glycaemic deterioration in type 2 diabetes
9. Correction to: Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia
10. Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes
11. Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion
12. GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting
13. Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function
14. Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion
15. Building the Glucagon-Like Peptide-1 Receptor Brick by Brick: Revisiting a 1993 Diabetes Classic by Thorens et al.
16. Plasma triacylglycerols are biomarkers of β-cell function in mice and humans
17. Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice
18. Glucokinase neurons of the paraventricular nucleus of the thalamus sense glucose and decrease food consumption
19. Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study
20. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes
21. Cold-induced dishabituation in rodents exposed to recurrent hypoglycaemia
22. A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion
23. Klf6 protects β-cells against insulin resistance-induced dedifferentiation
24. Use of preclinical models to identify markers of type 2 diabetes susceptibility and novel regulators of insulin secretion – A step towards precision medicine
25. Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes
26. Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk
27. SLC2A9 (GLUT9) mediates urate reabsorption in the mouse kidney
28. Allogeneic β-Islet Cells Correct Diabetes and Resist Immune Rejection
29. Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion
30. Normal Kinetics of Intestinal Glucose Absorption in the Absence of GLUT2: Evidence for a Transport Pathway Requiring Glucose Phosphorylation and Transfer into the Endoplasmic Reticulum
31. Fostering improved human islet research: a European perspective
32. Normal Hepatic Glucose Production in the Absence of GLUT2 Reveals an Alternative Pathway for Glucose Release from Hepatocytes
33. Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets
34. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes
35. Insulin Secretion is Regulated by the Glucose-Dependent Production of Islet β Cell Macrophage Migration Inhibitory Factor
36. The Drosophila TNF Eiger Is an Adipokine that Acts on Insulin-Producing Cells to Mediate Nutrient Response
37. Glucose transporter 2 mediates the hypoglycemia-induced increase in cerebral blood flow
38. Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing.
39. Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia.
40. Brain glucose sensing in homeostatic and hedonic regulation
41. Clic4, a novel protein that sensitizes β-cells to apoptosis
42. A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production
43. Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation
44. Hypoglycemia-Activated GLUT2 Neurons of the Nucleus Tractus Solitarius Stimulate Vagal Activity and Glucagon Secretion
45. Glucose-responsive neurons of the paraventricular thalamus control sucrose-seeking behavior
46. Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice
47. SAT-231 GL0034 (Utreglutide), a long acting, glucagon-like peptide-1 receptor agonist, improves body weight loss, lipid and liver injury markers in individuals with obesity: A phase 1 multiple ascending dose study
48. Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells
49. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment
50. Ins1 Cre knock-in mice for beta cell-specific gene recombination
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