Search

Background and Objectives Social isolation has been recognized as a social problem with negative health consequences. Using data from 3 waves of the Health and Retirement Study, this study aimed to examine the long-term impact of social isolation on loneliness and depressive symptoms and to explore the moderating effect of resilience. Research Design and Methods This study comprised 3,681 U.S. adults aged 60 and older at the baseline wave. Social isolation index was constructed using 5 indicators, including not married or cohabitating with a partner, no social participation, and less than monthly contacts with children, family members, or friends. Loneliness was measured by the University of California Los Angeles (UCLA) Loneliness Scale and depressive symptoms were measured by the Center for Epidemiological Studies—Depression scale. The moderator of resilience was assessed by the simplified resilience score. Latent growth curve models with robust standard errors were estimated. Results The results of latent growth curve models showed that social isolation was significantly associated with more initial loneliness and depressive symptoms. However, social isolation was associated with a slower increasing rate of loneliness, but no significant relationship with the change rate of depressive symptoms. Furthermore, resilience significantly buffered the negative effect of social isolation on the initial level of depressive symptoms. Discussion and Implications The findings underscore the importance of enacting strategies and interventions targeting resilience to address social isolation and its negative consequences among older adults. [ABSTRACT FROM AUTHOR]

Background and Objectives Social disconnectedness and loneliness pose significant challenges for older Chinese immigrants. Yet, it remains unclear whether they are associated with an increased risk of cognitive decline in this population. This study aimed to investigate the association of social disconnectedness and loneliness with cognitive functioning and examine the moderation role of neighborhood contexts. Research Design and Methods This longitudinal analysis examined a sample of individuals aged 60 years and older from the Population Study of Chinese Elderly in Chicago (N  = 2,044). Global cognition was assessed using the averaged z -scores of cognitive performance tests. Social disconnectedness was constructed using 5 indicators about structural aspects of social relationships. Loneliness was assessed with the R-UCLA loneliness scale. Neighborhood socioeconomic status (NSES) and neighborhood segregation index were constructed using 2010–2014 American Community Survey data at the census tract level. Individual perceptions about neighborhood environments were used to construct neighborhood cohesion index and neighborhood disorder index (NDI). Latent growth curve models with adjusted cluster robust standard errors were estimated. Results More loneliness was associated with a higher level of initial cognitive functioning (B  = 0.030, p  < .01), but also with a faster decline rate over time (B  = −0.007, p  < .01) after adjusting for covariates. High NSES and less neighborhood segregation buffered the negative effects of loneliness on cognitive decline, respectively. High NDI amplified the positive relationship between loneliness and initial functioning, but accelerated the rate of cognitive decline associated with loneliness. Discussion and Implications The study revealed that perceived loneliness, but not social disconnectedness, is a risk factor for cognitive decline among older Chinese immigrants. Living in a neighborhood with low socioeconomic status, more segregation, and high disorder elevated the detrimental effect of loneliness on long-term cognitive decline. Further research needs to investigate the complex interplay between social relationships, neighborhood environment, and cognition. [ABSTRACT FROM AUTHOR]

Background. Cellular senescence is thought to play a significant role in the onset and development of diabetic nephropathy. The goal of this study was to explore potential biomarkers associated with diabetic glomerulopathy from the perspective of senescence. Methods. Datasets about human glomerular biopsy samples related to diabetic nephropathy were systematically obtained from the Gene Expression Omnibus database. Hub senescence-associated genes were investigated by differential gene analysis and Least Absolute Shrinkage and Selection Operator analysis. Cluster analysis was employed to identify senescence molecular subtypes. A single-cell dataset was used to validate the above findings and further evaluate the senescence environment. The relationship between these genes and the glomerular filtration rate was explored based on the Nephroseq database. These gene expressions have also been explored in various kidney diseases. Results. Twelve representative senescence-associated genes (VEGFA, IQGAP2, JUN, PLAT, ETS2, ANG, MMP14, VEGFC, SERPINE2, CXCR2, PTGES, and EGF) were finally identified. Biological changes in immune inflammatory response, cell cycle regulation, metabolic regulation, and immune microenvironment have been observed across different molecular subtypes. The above results were also validated based on single-cell analysis. Additionally, we also identified several significantly altered cell communication pathways, including COLLAGEN, PTN, LAMININ, SPP1, and VEGF. Finally, almost all these genes could well predict the occurrence of diabetic glomerulopathy based on receiver operating characteristic analysis and are associated with the glomerular filtration rate. These genes are differently expressed in various kidney diseases. Conclusion. The present study identified potential senescence-associated biomarkers and further explored the heterogeneity of diabetic glomerulopathy that might provide new insights into the diagnosis, assessment, management, and personalized treatment of DN. [ABSTRACT FROM AUTHOR]

Objectives Residential segregation profoundly affects mental and physical health. However, impacts of residential segregation and other neighborhood characteristics on health among older Asian Americans are not fully understood. This study aimed to close this gap by examining effects of residential segregation, perceived neighborhood cohesion, and neighborhood disorder on all-cause mortality among older Chinese immigrants, as well as testing whether the association between residential segregation and mortality would be mediated by perceived neighborhood cohesion and neighborhood disorder. Methods Data were drawn from a subsample of 3,094 older Chinese Americans aged 60 and older (mean age = 72.8 years) from the Population Study of Chinese Elderly in Chicago. Residential segregation was derived using 2010–2014 American Community Survey data. Participants completed surveys on perceived neighborhood cohesion and neighborhood disorder between 2011 and 2013. All-cause mortality was tracked until December 2021. Results Residential segregation was associated with elevated all-cause mortality risk; this association, however, was no longer statistically significant after controlling for sociodemographic, behavioral, and health covariates. Perceived neighborhood cohesion, but not neighborhood disorder, was significantly associated with decreased mortality risks. There were no indirect effects of residential segregation on all-cause mortality through perceived neighborhood cohesion or neighborhood disorder. These effects were consistent across male and female participants. Discussion These results suggest the importance of neighborhood social environment, specifically perceptions of neighborhood cohesion, in influencing mortality risk among older Chinese immigrants. The findings also indicate the need to conduct further research to examine the health impact of residential segregation among this population. [ABSTRACT FROM AUTHOR]

Copyright of China Journal of Social Work is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background and Objectives Older Chinese immigrants are at risk for depression due to acculturative stress and language barriers. Residential segregation with respect to language use plays an important role in the mental health of historically marginalized populations. Previous research provided mixed evidence about the segregation effect among older Latino and Asian immigrants. Guided by a model of social processes, we examined the direct and indirect effects of residential segregation on depressive symptoms via multiple mechanisms of acculturation, discrimination, social network, social support, social strain, and social engagement. Research Design and Methods Four waves of depressive symptoms were assessed in the Population Study of Chinese Elderly (2011–19, N = 1,970), and linked to the 2010–14 American Community Survey estimates of neighborhood context. Residential segregation was measured by the Index of Concentrations at the Extremes which simultaneously assesses Chinese and English language use within a given census tract. Latent growth curve models with adjusted cluster robust standard errors were estimated after controlling for individual-level factors. Results Residents of segregated Chinese-speaking neighborhoods had fewer baseline depressive symptoms but a slower rate of symptom reduction than those living in neighborhoods segregated with English-only speakers. Racial discrimination, social strain, and social engagement partially mediated the association between segregation and baseline depressive symptoms; social strain and social engagement partially mediated the association with long-term reduction in depressive symptoms. Discussion and Implications This study demonstrates the importance of residential segregation and social processes in shaping mental well-being among older Chinese immigrants and suggests potential mechanisms to alleviate mental health risks. [ABSTRACT FROM AUTHOR]

An increasing number of custodial grandparents are raising grandchildren, and intensive childcare is stressful with many negative personal, interpersonal, economic, and health implications. Grandparents' strengths, including resilience, positive caregiving appraisal, and social support should be considered in the face of parenting stress and adversity. Guided by the stress and resilience model, the current study investigated the associations of parenting stress and coping resources with life satisfaction and mental wellness among custodial grandparents (N = 76). Data were collected between December 2020 and April 2021, through collaborations with community-based agencies located in two metropolitan areas, which provide supportive services to custodial grandparents and their families. Findings showed that more parenting stress was associated with less life satisfaction and worse mental health, and that stress management boosted life satisfaction and mental wellness. Grandparents with more informal social support and social service utilization fared better than their counterparts with less social support and no experience of service use. The results of this study suggest that social work interventions should focus on improving stress management to cope with daily and caregiving stressors. Social workers can help with informal social support and formal social services utilization to address caregiving needs among custodial grandparents. [ABSTRACT FROM AUTHOR]

Volunteering is viewed as an empowerment process whereby older adults actively participate in the community and improve their well-being and health. Yet little is known about racial differences in volunteering, and even less in terms of perceived benefits from volunteering as a means of empowerment. The present study addresses this research gap by examining the differences in volunteer experience and perceived benefits from volunteering between older black people and white people. Purposive and convenience samples were drawn from the city of Pittsburgh and questionnaires were completed by 180 adults ages 60 and over. Bivariate and multivariate analyses showed that black participants were less likely than their white counterparts to volunteer in formal organizations; however, once engaged, they committed more time and perceived more psychosocial benefits from volunteering. Also volunteering and self-reported health demonstrated a stronger relationship in the black sample than among the white sample. This study suggests that black older adults have more to gain from volunteer engagement and feel empowered through meaningful involvement in the community and improved physical and emotional quality of life.

Purpose: This study tested a theoretical model of volunteering benefits and examined the mechanism through which volunteering benefits older adults. Design and Methods: This is a 2-wave study of 253 older adult volunteers serving in 10 volunteer programs. Older volunteers completed the mailed surveys in 2005 and 2006. Structural equation modeling was used to define the latent variables and to test direct and indirect relationships among organizational support, socioemotional benefits, and self-reported health. Results: Organizational support (measured by choice of volunteer activity, training, and ongoing support) had significant direct associations with 2 latent factors of socioemotional benefits, that is, perceived contribution and personal benefits. Perceived contribution was significantly related to mental health. Additionally, older volunteers with lower socioeconomic status (SES) committed more hours and perceived more personal benefits than higher SES peers. Implications: These findings suggest that volunteer programs can provide various organizational supports to older volunteers, especially to low-SES volunteers, in order to promote the socioemotional and health benefits of volunteering to older adults. Psychological well-being of older adults can be improved through engagement in meaningful volunteer activities and contribution to others.

As more nonprofit organizations rely on older adult volunteers to provide services, it is important to retain volunteers for an extended period of time to ensure service quality and the beneficial outcomes of volunteering. Nonprofit organizations are positioned to facilitate older adult volunteers' role performance. Based on an institutional perspective on volunteering, this study explored what institutional facilitations are needed for sustained volunteering. The sample included 401 older adult volunteers from 13 programs across the nation. Data were collected by means of self-administrated questionnaires. Institutional facilitation was captured by volunteer role flexibility, incentive, role recognition, and training. With volunteers' age controlled for, two-level hierarchical linear models were used to assess the relationship between volunteer duration (level 1 variables) and institutional facilitation (level 2 variables) in the volunteer program. Results demonstrated that a higher level of volunteering duration was associated with institutional facilitation factors of more role recognition and more training hours. Duration was also associated with less incentive. These findings suggest that certain facilitators from organizations contribute to an extended period of commitment among older adult volunteers.

Purpose: The purpose of this study was to document the benefits of volunteering perceived by older adults and to explain variation in these self-perceived benefits. Design and Methods: This is a quantitative study of 13 volunteer programs and 401 older adults serving in those programs. Program directors completed telephone interviews, and older volunteers completed mailed surveys. Volunteer-level and program-level data were merged. Results: Older volunteers reported a wide variety of benefits to the people they served, themselves, their families, and communities. More than 30% reported that they were "a great deal better off" because of volunteering, and almost 60% identified a benefit to their families. When considering only individual characteristics, lower-income and lower-educated volunteers reported more benefit. Yet, aspects of the volunteer experience, like amount of involvement, adequacy of training and ongoing support, and stipends, were more important in understanding who benefits from volunteering. Implications: These findings suggest that characteristics of volunteer programs can be strengthened to maximize the benefits of volunteering to older adults. These characteristics are more mutable by public policies and organizational procedures than individual characteristics. Focusing on the recruitment of lower socioeconomic status older adults may result in an increase in benefits from the growth of volunteering.

Few studies have focused on activity engagement among older immigrants. We aim to map the patterns of activity engagement and examine the associations with social-ecological factors in a sample of older Chinese immigrants. Participants were from the Population Study of Chinese Elderly in Chicago (PINE). Four patterns of activity engagement were identified through latent class analysis: restricted, diverse, informal social, and community-based social. Intrapersonal, interpersonal, cultural, and environmental factors distinguished latent classes of activity engagement. In particular, acculturation and family-oriented immigration differentiated the restricted from the diverse class membership. Positive attributes of social environment such as social network size, positive social support, and neighborhood cohesion were associated with the likelihood of categorization in the diverse, informal social, and community-based social groups relative to the restricted group. Findings point to the importance of positive attributes of social environment in enhancing engagement with life among older Chinese immigrants. [ABSTRACT FROM AUTHOR]

Objectives: Immigration is a stressful experience. Social interactions with family members and friends play an important role in the health and well-being of immigrant older adults. This study examined the association between different domains of acculturation and depressive symptoms among older Chinese immigrants in the United States and investigated the roles of positive and negative interactions with family and friends in such associations. Method: We used data from the Population Study of Chinese Elderly (PINE), a population-based survey of community-dwelling Chinese older adults in the Greater Chicago area (N = 3,158). Depressive symptoms were measured by the PHQ-9. Acculturation, positive and negative social interactions with partner/family/friends were all measured by standard scales. Binary logistic regression models were used to examine the relationship between acculturation and the probability of having depressive symptoms. Results: Results showed that only social acculturation was correlated with a higher likelihood of having depressive symptoms after controlling for relevant sociodemographic variables. Results also demonstrated that 'high positive & high negative', as well as 'high positive & low negative' social interactions had significant moderating effects on the association between media acculturation and depressive symptoms. Conclusion: The study findings suggest that although older Chinese immigrants in the United States with high levels of social acculturation are vulnerable to depressive symptoms, high positive social interactions with partner/family/friends buffer the relationship between media acculturation and depressive symptoms. Community services can help with social acculturation and more positive interactions from partner/family/friends to alleviate depressive symptoms among older Chinese immigrants. [ABSTRACT FROM AUTHOR]

Objectives Although a number of studies have documented cognitive health among older immigrants in the United States, little is known about how the life-course immigration experiences are associated with cognitive trajectories among older Chinese immigrants. We assess patterns of cognitive functioning and change over time and examine whether age at migration, reasons for migration, acculturation, perceived discrimination, and preferred dialects are related to cognitive trajectories. Methods The sample comprised 2,075 participants from the Population Study of Chinese Elderly (PINE), who completed a battery of cognitive tests at four time points (2011–2019). Latent class growth analysis and multinomial logistic regression were utilized. Results Three latent classes of cognitive trajectories were identified: the low functioning with the fastest decline (LCF, 12%), the moderate functioning with a medium decline rate (MCF, 39%), and the high functioning with the slowest decline (HCF, 48%). Perceiving more discrimination reduced, whereas speaking Taishanese increased the odds of being in the LCF and MCF. High acculturation only distinguished MCF from HCF after controlling for the known factors of cognitive health such as age, education, and social engagement. Discussion This study identifies a group of older Chinese immigrants who are especially vulnerable to cognitive impairment and indicates that the risk of cognitive decline appears to be elevated with lower levels of acculturation and unidentified racial discrimination. More research is needed to fully understand the underlying mechanisms that link the life-course immigration experiences to cognitive health outcomes in later life. [ABSTRACT FROM AUTHOR]

Objectives: The present study aims to identify distinct types of relationships between grandparents and their adult children, measure the associations between these relationship types and depressive symptoms among grandparents, and determine whether these associations vary by grandparent status. Method: This study uses data from a sample of 1,196 grandparents age 51 and older from the 2014 Health and Retirement Study. Latent class analysis (LCA) is applied and identifies types of grandparent–adult children relationships. Ordinary Least Squares (OLS) regression models are used to estimate the association between relationship types and depressive symptoms by grandparent status. Results: LCA identified four grandparent-adult children relationship types: amicable, ambivalent, detached, and disharmonious. Custodial and co-parenting grandparents were most likely to report having an ambivalent relationship with their adult children. Among co-parenting and custodial grandparents, disharmonious relationships were associated with more depressive symptoms. Conclusion: Interventions are suggested to improve emotional relationships with adult children and dyadic family relationships among grandparent families. [ABSTRACT FROM AUTHOR]

Purpose: This study tested a theoretical model of volunteering benefits and examined the mechanism through which volunteering benefits older adults. Design and Methods: This is a 2-wave study of 253 older adult volunteers serving in 10 volunteer programs. Older volunteers completed the mailed surveys in 2005 and 2006. Structural equation modeling was used to define the latent variables and to test direct and indirect relationships among organizational support, socioemotional benefits, and self-reported health. Results: Organizational support (measured by choice of volunteer activity, training, and ongoing support) had significant direct associations with 2 latent factors of socioemotional benefits, that is, perceived contribution and personal benefits. Perceived contribution was significantly related to mental health. Additionally, older volunteers with lower socioeconomic status (SES) committed more hours and perceived more personal benefits than higher SES peers. Implications: These findings suggest that volunteer programs can provide various organizational supports to older volunteers, especially to low-SES volunteers, in order to promote the socioemotional and health benefits of volunteering to older adults. Psychological well-being of older adults can be improved through engagement in meaningful volunteer activities and contribution to others. Key Words: Volunteerism & civic engagement, Organizational support, Socioemotional benefit, Health doi: 10.1093/geront/gnq020

This paper reports a United States study of the factors that influence the turnover of older adult volunteers. Based on a parent study of programmes that use older adult volunteers, the follow-up study examined the experience for 207 older volunteers who served in ten programmes in 2005 and 2o06, respectively. Telephone interviews and mail surveys were used to collect programme and personal information. The findings indicated that aspects of the volunteer experience, like duration of involvement, volunteering in other programme(s), type of activity, the adequacy of on-going support, and the availability of stipends influenced volunteering retention and turnover. Respondents who volunteered for a longer period were committed in other programmes, felt better supported, and received a stipend were less likely to quit volunteering in a designated programme. Also those volunteering in public safety programmes were least likely to quit. As reported by older adult volunteers themselves, the primary reasons for volunteer withdrawal included a higher priority of another productive activity or commitment, declining health, and problems with the programme administration. Volunteers with extensive experience were least likely to withdraw. The findings suggest that organisations with volunteer programmes can promote older adults' long-term engagement as volunteers by providing on-going support and stipends. Changes in programme characteristics would impact positively on volunteer retention, especially among low-income older Americans. KEY WORDS--older adult volunteer, volunteer turnover, organisational facilitation. doi: 10.1017/S0144686X10000140

The authors used the Andersen model to compare older adults' help seeking from clergy to help seeking from other sources of formal mental health services. Data were from the Naturally Occurring Retirement Community Demonstration Project. Multinomial logistic regression was used to compare sources from which help was sought. The results indicate that older adults sought help from clergy more frequently than from other formal sources. Increased stress levels, higher intrinsic religiosity, and being younger were related to seeking help from clergy. Greater stress and attendance at religious services were related to help seeking from other sources. Only greater frequency of attending religious services was associated with a greater likelihood of seeking help from clergy versus other formal providers. The increasing elderly population and the attendant crisis in mental health services might best be addressed through public-private partnerships in which mental health professionals assist clergy in identifying problems and making appropriate referrals. Keywords mental health services, older adults, help seeking, religion, religiosity, NORC, clergy DOI:10.1177/0164027509343539

Purpose: The purpose of this study was to document the benefits of volunteering perceived by older adults and to explain variation in these self-perceived benefits. Design and Methods: This is a quantitative study of 13 volunteer programs and 401 older adults serving in those programs. Program directors completed telephone interviews, and older volunteers completed mailed surveys. Volunteer-level and program-level data were merged. Results: Older volunteers reported a wide variety of benefits to the people they served, themselves, their families, and communities. More than 30% reported that they were 'a great deal better off' because of volunteering, and almost 60% identified a benefit to their families. When considering only individual characteristics, lower-income and lower-educated volunteers reported more benefit. Yet, aspects of the volunteer experience, like amount of involvement, adequacy of training and ongoing support, and stipends, were more important in understanding who benefits from volunteering. Implications: These findings suggest that characteristics of volunteer programs can be strengthened to maximize the benefits of volunteering to older adults. These characteristics are more mutable by public policies and organizational procedures than individual characteristics. Focusing on the recruitment of lower socioeconomic status older adults may result in an increase in benefits from the growth of volunteering. Key Words: Civic engagement, Older adults, Outcomes of volunteering

Guided by a convoy model of social relations, this study explores the complex relationships between loneliness, age at immigration, familial relationships, and depressive symptoms among older immigrants. This study used 2010 Health and Retirement Study data from a sample of 575 immigrants (52% female, age range 65–99 years). Ordinary least squares regression models were estimated. The findings indicate that for older immigrants who came to the United States at age 45 or older, loneliness was significantly positively associated with depressive symptoms. Further, perceived negative strain and hours spent helping family moderated this relationship such that the effect of loneliness on depressive symptoms was stronger among respondents who perceived more negative family strain and spent fewer hours helping family. Familial relationships are crucial for the psychological well-being of older immigrants because they can be a source of either stress or support. The results have implications for how research and practices can support the immigrant families. [ABSTRACT FROM AUTHOR]

This study examined the longitudinal association of depressive symptoms with grandchild care intensity and whether the association varies by household structure, residential area, and gender for Chinese grandparents. Using data from three waves of the China Health and Retirement Longitudinal Study (CHARLS, 2011–2015), we applied multilevel mixed effects models to examine changes in depressive symptoms and the associations with caregiving intensity and to test the moderation effects of residence, living arrangement, and gender. After controlling for sociodemographic and health covariates, we found that providing a medium level of grandchild care was associated with fewer baseline depressive symptoms compared with non-caregivers. Providing low-level care among those living with spouse/partner and among those living with child(ren)/others was associated with fewer depressive symptoms relative to non-caregivers with similar living arrangements. Findings indicate that a medium level of involvement in childcare was associated with better mental wellness and low levels of caregiving may benefit nonresidential caregivers. More prospective longitudinal studies are needed to improve the operationalization of grandparent caregiving, validate the associated health outcomes, and apply a contextual approach to examine socioeconomic, cultural, and policy-related contexts of caregiving in the changing world of China. [ABSTRACT FROM AUTHOR]

Social isolation has been recognized as a critical public health problem. As the most vulnerable population, older adults are disproportionately affected by social isolation during the COVID-19 pandemic. The purposes of this study were to examine the association between social isolation and loneliness among U.S. older adults and to explore the moderating effect of solitary activity by using data from the Health and Retirement Study (HRS). Social isolation was measured by six indicators, including marital status, living arrangement, social participation in any clubs or social organizations, and the frequency of social contact with children, family members, and friends. Loneliness was assessed by eleven questions derived from the UCLA Loneliness Scale. Solitary activity included 11 types of activities that respondents could perform alone with limited or no social interaction. Results from the multivariate regression analyses indicated that unmarried status and lower frequency of social contact were associated with more perceived loneliness. Solitary activity significantly moderated the negative effects of the low frequency of social contact with family members on loneliness. The findings implicate that social work programs and interventions can aim to expand social networks and provide more opportunities for solitary activities, particularly for isolated older adults. [ABSTRACT FROM AUTHOR]

This study examines how older adults access organizational volunteer roles and what socio-structural factors are associated with the access. Using the data from the Current Population Survey (U.S. Department of Commerce, Bureau of the Census, 2002), bivariate analyses show that there are variations in access to volunteer roles across types of organizations. Results from multinomial logistic regressions indicate that education, income, age, and race are associated with the ways that older adults access volunteer roles. Voluntary organizations are advised to approach older adults directly, use current volunteers to recruit potential ones, publicize their organizational goals, and disseminate relevant information in efforts to improve access of older adults to volunteer roles. KEYWORDS. Organizational volunteer, access, older adults, organization type, socio-structural factor

This study describes support service utilization of persons with multiple sclerosis, identifies factors that best predict service use, and discusses implications of current service utilization for professional and policy practice. Random sample survey data were collected (N=580). Analyses using ANOVA, chi square, binary and ordinal logistic and multivariate regressions were completed. Results indicate personal assistance and assistive technology are heavily used and highly correlated; formal service is limited. Demographic, disability, and health insurance variables are predictive of service use. Results suggest persons with MS are reliant primarily on technology and family members to help meet daily living needs. Sustaining informal supports is discussed in relation to aging with MS., There are approximately 400,000 individuals with multiple sclerosis (MS) living in the United States and approximately 2,500,000 persons with MS around the world (National Multiple Sclerosis Society, 2004). These individuals [...]

Objectives. This study tests the effects of volunteering on the well-being of older adults, including the effect of level of engagement, the moderating effects of demographic and social factors, and the effects of the nature of the volunteer experience. Methods. This is a secondary data analysis of three waves of data from the Americans' Changing Lives Study. Self-rated health, functional dependency, and depression are regressed on the well-being measures from the previous waves, other control variables and volunteer status, volunteer hours, type and number of volunteer organizations, and the perceived benefit to others of the volunteer work. Results. Older adults who volunteer and who engage in more hours of volunteering report higher levels of well-being. This positive effect was not moderated by social integration, race, or gender. There was no effect of the number of organizations for which the older adult volunteered, the type of organization, or the perceived benefit of the work to others. Discussion. This work contributes to a knowledge base that points to the development of social programs and policies that maximize the engagement of older adults in volunteer roles. The findings suggest that targeting efforts may not be warranted, in that there are not differential benefits according to personal characteristics of the volunteer. Future studies have to address the nature of the social institutions that will maximize the number of elders in these roles and the benefits that they accrue.

Guided by a convoy model of social relations, this study investigates the relationships between grandparenting status, social relations, and mortality among community-dwelling grandparents age 65 and older who are caring for their grandchildren. The data were drawn from the 2008 and 2016 waves of the Health and Retirement Study (N = 564). Latent class analysis was used to identify the social network structure based on six indicators of interpersonal relationships and activities. A series of hierarchical Weibull hazard models estimated the associations between grandparent caregiving, social relations, and mortality risk. Results of survival analyses indicate that co-parenting and custodial grandparents had higher all-cause mortality risk than grandparents who babysat occasionally; however, for custodial grandparents, the association was not significant once social relation variables were added to the model. This study suggests that community-based support may be beneficial to older grandparents and improved relationship quality is integral to the well-being of older adults. [ABSTRACT FROM AUTHOR]

This study investigates the differential associations of activity engagement and perceived neighborhood characteristics (i.e., cohesion, disorder, sense of community) with cognitive measures. Using data of 2,713 Chinese older adults in Chicago, who completed two interviews between 2011 and 2015, we identified three activity domains: reading, social, and games. In general, engagement in more reading and social activities was associated with better baseline cognitive function, but the positive effects tapered off over time in some cases. Neighborhood cohesion had both direct and indirect effects on cognitive function. Engagement in social activities mediated the neighborhood cohesion effects, that is, living in a cohesive neighborhood promoted social activities and consequently benefited cognitive function. Findings speak to the importance of activity engagement and neighborhood cohesion for cognition among the U.S. Chinese older adults. Future research is needed to investigate the longitudinal relationships of activity engagement and environmental factors with cognitive change. [ABSTRACT FROM AUTHOR]

For a more insightful investigation into the specificity of bacterial heparinase I, a series of structurally well-defined heparin oligosaccharides was synthesized using a highly efficient chemoenzymatic strategy. Apart from the primary cleavage site, five glycosidic linkages of oligosaccharides with varying modifications to obtain secondary cleavage sites were degraded by a high concentration of heparinase I. The reactivity of linkages toward heparinase I was not entirely dependent on the 2- O -sulfated iduronic acid being cleaved or the neighboring 6- O -sulfated glucosamine residues, but it was dependent on higher degrees of sulfation of oligosaccharides and indispensable N -substituted glucosamine adjacent to the cleavable linkage. Moreover, the enzyme demonstrated less preferential cleavage toward glycosidic linkages containing glucuronic acid than those containing iduronic acid of the counterpart oligosaccharides. Biolayer interferometry revealed differences in reactivity that are not completely consistent with different affinities of substrates to enzyme. Our study presented accurate information on the cleavage promiscuity of heparinase I that is crucial for heparin depolymerization. • Heparin oligosaccharides were chemoenzymatically synthesized as substrates of heparinase I. • Five secondary cleavage sites of oligosaccharides were degraded to less extents by heparinase I. • The enzymatic reactivity was dependent on different modification of uronic acid or GlcN. • Heparinase I had less preferential cleavage towards GlcA-formed linkages than IdoA. • BLI proved differences in reactivity are partially consistent with substrate affinity to enzyme. [ABSTRACT FROM AUTHOR]

Older adults with memory loss often require assistance from caregivers to manage their medications. This study examined the efficacy of a problem-solving-based intervention focused on caregiver medication management, problem solving, self-efficacy, and daily hassles. Caregiver health-related quality of life (HRQoL) and patient health care utilization were secondary outcomes. Totally, 83 patients (age 79.9±8.8 years) and their informal caregivers (age 66.9±12 years, female 69.9%, White 85.5%) were randomized; data collection occurred at baseline, 8, 16, and 24 weeks. Linear mixed modeling showed significant decreases in medication deficiencies which were sustained over time. No significant changes in caregiver problem solving, daily hassles, or patient health care utilization occurred between groups or over time. In addition, caregiver self-efficacy and mental HRQoL decreased in both groups. Physical HRQoL decreased in the intervention group, yet increased in the usual care group. Future research should investigate these outcomes in larger and more diverse samples. [ABSTRACT FROM AUTHOR]

A major challenge facing an aging society is the increased caregiving needs among community-dwelling older adults with chronic conditions. Reliance on social relations may help address caregiving needs and maintain older adults' mental well-being. This study examines the roles of different aspects of social relations—social network size, social support, and service use—in the association between caregiving needs and mental health status (MHS). Using a sample of adults age 55 and over in an urban setting, authors tested the direct, mediation, and moderation effects models of social relations. Structural equation modeling was applied and latent variables of caregiving needs, MHS, and social network size were identified. Results showed that caregiving needs and informal social support (that is, network size, positive support, and negative strain) were directly related to MHS and that informal social support partially mediated the negative effect of caregiving needs on MHS; by contrast, service use moderated the association, indicating that those with caregiving needs who used more services were in better MHS than their counterparts with less service use. Findings point to the importance of social work interventions aimed at improving social relations and enhancing awareness and access to social services. [ABSTRACT FROM AUTHOR]

OBJECTIVES: We aimed to examine the associations between immigration‐related factors and prevalent and incident cognitive impairment (CI) and whether the associations varied by sex among US Chinese older adults. DESIGN: Two‐wave prospective study. SETTING: The greater Chicago area. PARTICIPANTS: Community‐dwelling adults aged 60 and older who self‐identified as Chinese, who were interviewed at two time points during 2011‐2013 (N = 3157) and 2013‐2015 (N = 2713). MEASUREMENTS: CI was assessed by the 30‐item Chinese Mini‐Mental State Examination (C‐MMSE). CI prevalence was determined by the percentage of respondents whose C‐MMSE score was below 18 at baseline (N = 3033), and CI incidence was determined by the percentage of the respondents whose score was 18 or above at baseline (N = 2443) but dropped below 18 at wave 2. Immigration‐related factors included age at migration, immigration reasons, and acculturation. RESULTS: The CI prevalence rate was 7.62% at baseline, and the incidence rate was 5.12% at wave 2. Women were more likely than men to have CI, consisting of 77.06% and 75.20% among persons with CI at the time points. None of the immigration‐related factors were related to CI prevalence and incidence. Older age, fewer years of education, and more instrumental activities of daily living limitations were risk factors of CI in the whole, male, and female samples. CONCLUSION: Older Chinese women were generally disadvantaged in cognition and overall health as compared with older Chinese men. Yet immigration experience does not link to CI for both men and women after equalizing the well‐established effects of age and education on cognition. Future research needs to investigate whether the risk of CI in late life is related to the biological and contextual factors earlier in the life course. Decreasing sex disparities in the risk of dementia may focus on reducing educational and health disparities in the early life stage. J Am Geriatr Soc 67:S513–S518, 2019. [ABSTRACT FROM AUTHOR]

OBJECTIVES: To examine whether and how early‐life experiences such as years of schooling affect late‐life cognitive function through a pathway of activity engagement. DESIGN: Prospective. SETTING: We used data from 2 waves of the Population Study of Chinese Elderly in Chicago (PINE). PARTICIPANTS: PINE is the largest population‐based epidemiological study of Chinese‐American adults aged 60 and older in the greater Chicago area. Wave 1 data were collected for 2 years, from July 2011 to June 2013, and Wave 2 data were collected from 2013 to 2015; total sample size was 2,713. MEASUREMENTS: Education was measured in years of schooling. Activity engagement was assessed using 15 items grouped into two clusters: cognitive activity and social activity. Cognitive function was evaluated using five instruments to assess general mental status (Chinese Mini‐Mental State Examination (C‐MMSE)), episodic memory, perceptual speed, working memory, global cognition score. RESULTS: Adjusting for sociodemographic and health‐related control variables, education measured at Wave 1 was associated with better global cognition (b = 0.025, p < .001), C‐MMSE (b = .037, p < .001), episodic memory (b = .026, p < .001), Symbol Digit Modalities Test perceptual speed (b = .036, p < .001), and Digit Span Backward working memory (b = .047, p < .001) at Wave 2. Activity engagement, cognitive activity in particular, significantly mediates the effect of education on all cognitive tests, with the size of the mediating effect ranging from 16% to approximately 24%. CONCLUSION: Amount of schooling early in life is significantly related to late‐life cognitive function in virtually all domains, and cognitive activity is one of many links between the two. J Am Geriatr Soc 67:S525–S531, 2019 [ABSTRACT FROM AUTHOR]

This study aims to assess racial differences in subjective wellbeing (SWB) and to examine whether the pathways of social support and social engagement to SWB vary by racial groups in the United States of America. Using a local sample (N = 1,035) and a nationally representative sample of the Health and Retirement Study (N = 7,718), we compared life satisfaction and happiness between non-Hispanic Whites and Blacks aged 55 and over. We evaluated the extent to which race, other socio-demographic characteristics, health, social engagement and social support explained the variances in SWB and examined the moderation effects of race on the relationships of SWB with age, social support and social engagement. Multiple regression analyses showed that non-Hispanic Blacks were at least as satisfied as, and even happier than White peers, after equalising social resources and health variables. Social support was significantly related to SWB, and it seemed that positive support was more important to Whites than to Blacks in predicting life satisfaction. In addition, the racial crossover effect existed, that is, the old-old (80+) Blacks were happier than their White peers. Findings indicate a national trend of the race paradox in SWB and underscore the importance of social support in promoting older adults' wellbeing. Future research is recommended to investigate other potential mechanisms among Black older Americans to explain their relatively better SWB. [ABSTRACT FROM AUTHOR]

This study aims to examine the effect of the death of a family member or friend on psychological well-being, specifically the moderating effects of first-time volunteering and social network. With the sample of 354 volunteers from the Experience Corps® (EC) programs, Analysis of covariance (ANCOVA) estimated the differences in psychological well-being. Among volunteers who had experienced the death of a family member or friend, new volunteers showed significant improvement in positive affect compared to experienced volunteers. EC members gained additional social contacts through volunteering. Formal volunteering has a salutatory effect on older adults' health after the loss of family members. [ABSTRACT FROM AUTHOR]

Resilience plays a significant role in buffering the negative effects of parenting stress among custodial grandparents. Using a sample of 76 custodial grandparents, this study aimed to investigate the psychometric properties and factor structure of the 10-item Connor–Davidson Resilience Scale and to examine the predictors at individual level (demographic characteristics and stress management), interpersonal level (positive social support and negative social support), and community level (formal service use). The results of exploratory and confirmatory factor analyses yielded two factors: adaptability and persistence, and positivity. The findings suggest that low levels of stress management and negative social support may undermine resilience in coping with parenting stress. This study emphasizes the significance of both individual and family interventions in fostering resilience among custodial grandparents by aiding them in building stress management skills and improving the quality of social relationships. [ABSTRACT FROM AUTHOR]

Objective: This study examined the associations of neighborhood characteristics and living arrangements with physical and mental health among older Chinese Americans. Method: A sample of 3,159 community-dwelling Chinese older adults in the Greater Chicago area provided reports of health, socio-demographic characteristics, living arrangements, social cohesion, and neighborhood disorder. We used multinomial logistic, Poisson, and negative binominal regression analyses. Results: Neighborhood disorder was consistently associated with negative health indicators, including poor self-reported health, more chronic conditions, depressive symptoms, and anxiety symptoms. Findings about the relationships between social cohesion and health indicators were mixed. Social cohesion was more salient to mental health for those living with spouse, children, and/or grandchildren relative to those living with spouse only. Discussion: Policies and interventions are needed to improve the physical and social environments of neighborhoods and to promote healthy aging among Chinese older adults and in the general population as well. [ABSTRACT FROM AUTHOR]