Search

Your search keyword '"TRIPODI P."' showing total 620 results
Start Over Author "TRIPODI P." Publication Type Academic Journals
620 results on '"TRIPODI P."'

1. A common marker of affect recognition dysfunction in the FTD spectrum of disorders.

Author

Canu, Elisa, Castelnovo, Veronica, Aiello, Edoardo, De Luca, Giulia, Sibilla, Elisa, Freri, Fabiola, Tripodi, Chiara, Spinelli, Edoardo, Cecchetti, Giordano, Magnani, Giuseppe, Caso, Francesca, Caroppo, Paola, Prioni, Sara, Villa, Cristina, Tremolizzo, Lucio, Appollonio, Ildebrando, Verde, Federico, Ticozzi, Nicola, Silani, Vincenzo, Sturm, Virginia, Rankin, Katherine, Gorno-Tempini, Maria, Poletti, Barbara, Filippi, Massimo, and Agosta, Federica

Subjects
Humans, Supranuclear Palsy, Progressive, Reproducibility of Results, Affect, Neuropsychological Tests, Aged, Middle Aged, Female, Male, Frontotemporal Dementia, Recognition, Psychology
Abstract

BackgroundPoor affect recognition is an early sign of frontotemporal dementia (FTD). Here, we applied the abbreviated version of the Comprehensive Affect Testing System (CATS-A) battery to Italian FTD cases and healthy controls (HC) to provide cut-offs of emotional dysfunction in the whole group and in different FTD clinical syndromes.MethodsOne hundred thirty-nine FTD patients (60 behavioural variant [bvFTD],13 semantic behavioural variant of FTD [sbvFTD], 28 progressive supranuclear palsy [PSP], 21 semantic [svPPA] and 17 nonfluent [nfvPPA] variants of primary progressive aphasia) and 116 HC were administered the CATS-A, yielding an Affective Recognition Quotient (ARQ), which was used as outcome measure. Age- and education-adjusted, regression-based norms were derived in HC. In patients, the ARQ was assessed for its internal reliability, factorial validity and construct validity by testing its association with another social cognition paradigm, the Story-Based Empath Task (SET). The diagnostic accuracy of the ARQ in discriminating patients from HC, genetic cases from HC and patient groups among each other was tested via ROC analyses.ResultsIn the whole FTD cohort, CATS-A proved to be underpinned by a mono-component factor (51.1%) and was internally consistent (McDonalds ω = 0.76). Moreover, the ARQ converged with the SET (r(122) = 0.50; p

Published
2025

4. How to detect affect recognition alterations in amyotrophic lateral sclerosis

Author

Castelnovo, Veronica, Canu, Elisa, Aiello, Edoardo Nicolò, Curti, Beatrice, Sibilla, Elisa, Torre, Silvia, Freri, Fabiola, Tripodi, Chiara, Lumaca, Laura, Spinelli, Edoardo Gioele, Schito, Paride, Russo, Tommaso, Falzone, Yuri, Verde, Federico, Silani, Vincenzo, Ticozzi, Nicola, Sturm, Virginia E., Rankin, Katherine P., Gorno-Tempini, Maria Luisa, Poletti, Barbara, Filippi, Massimo, and Agosta, Federica

Published
2024
Full Text
View/download PDF

7. Magnetic-field-driven targeting of exosomes modulates immune and metabolic changes in dystrophic muscle

Author

Villa, Chiara, Secchi, Valeria, Macchi, Mirco, Tripodi, Luana, Trombetta, Elena, Zambroni, Desiree, Padelli, Francesco, Mauri, Michele, Molinaro, Monica, Oddone, Rebecca, Farini, Andrea, De Palma, Antonella, Varela Pinzon, Laura, Santarelli, Federica, Simonutti, Roberto, Mauri, PierLuigi, Porretti, Laura, Campione, Marcello, Aquino, Domenico, Monguzzi, Angelo, and Torrente, Yvan

Published
2024
Full Text
View/download PDF

11. An open source knowledge graph ecosystem for the life sciences

Author

Callahan, Tiffany J, Tripodi, Ignacio J, Stefanski, Adrianne L, Cappelletti, Luca, Taneja, Sanya B, Wyrwa, Jordan M, Casiraghi, Elena, Matentzoglu, Nicolas A, Reese, Justin, Silverstein, Jonathan C, Hoyt, Charles Tapley, Boyce, Richard D, Malec, Scott A, Unni, Deepak R, Joachimiak, Marcin P, Robinson, Peter N, Mungall, Christopher J, Cavalleri, Emanuele, Fontana, Tommaso, Valentini, Giorgio, Mesiti, Marco, Gillenwater, Lucas A, Santangelo, Brook, Vasilevsky, Nicole A, Hoehndorf, Robert, Bennett, Tellen D, Ryan, Patrick B, Hripcsak, George, Kahn, Michael G, Bada, Michael, Baumgartner, William A, and Hunter, Lawrence E

Subjects
Information and Computing Sciences, Artificial Intelligence, Bioengineering, Data Science, Networking and Information Technology R&D (NITRD), Algorithms, Biological Science Disciplines, Pattern Recognition, Automated, Translational Research, Biomedical, Knowledge Bases
Abstract

Translational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these data, but researchers face significant integration challenges. Knowledge graphs (KGs) are used to model complex phenomena, and methods exist to construct them automatically. However, tackling complex biomedical integration problems requires flexibility in the way knowledge is modeled. Moreover, existing KG construction methods provide robust tooling at the cost of fixed or limited choices among knowledge representation models. PheKnowLator (Phenotype Knowledge Translator) is a semantic ecosystem for automating the FAIR (Findable, Accessible, Interoperable, and Reusable) construction of ontologically grounded KGs with fully customizable knowledge representation. The ecosystem includes KG construction resources (e.g., data preparation APIs), analysis tools (e.g., SPARQL endpoint resources and abstraction algorithms), and benchmarks (e.g., prebuilt KGs). We evaluated the ecosystem by systematically comparing it to existing open-source KG construction methods and by analyzing its computational performance when used to construct 12 different large-scale KGs. With flexible knowledge representation, PheKnowLator enables fully customizable KGs without compromising performance or usability.

Published
2024

20. HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling

Author

Terri, Michela, Sandoval, Pilar, Bontempi, Giulio, Montaldo, Claudia, Tomero-Sanz, Henar, de Turris, Valeria, Trionfetti, Flavia, Pascual-Antón, Lucía, Clares-Pedrero, Irene, Battistelli, Cecilia, Valente, Sergio, Zwergel, Clemens, Mai, Antonello, Rosanò, Laura, del Pozo, Miguel Ángel, Sánchez-Álvarez, Miguel, Cabañas, Carlos, Tripodi, Marco, López-Cabrera, Manuel, and Strippoli, Raffaele

Published
2024
Full Text
View/download PDF

27. To What Extent Is Criminal Justice Content Specifically Addressed in MSW Programs? A 10 Year Review and Update

Author

Phillipe Copeland, Christopher J. Collins, Shelby D. Pederson, Stephen Tripodi, and Matthew W. Epperson

Abstract

This study examined the prevalence and types of criminal justice content being offered in Council on Social Work Education programs. Data were collected through questions sent via e-mail to program administrators and content analysis of school websites for three hundred and eight MSW programs. Criminal justice content was measured in three main areas: (a) dual- or joint-degree options, (b) concentrations or specializations, and (c) courses. The results show that most MSW programs do not cover criminal justice content. Less than one-fourth of programs had a dual-degree or joint-degree program (n=54, 17.5%), a specialization or concentration (n=17, 5.5%), or a course specific to criminal justice (n=74, 24%). Social work education must do more to include criminal justice content in its MSW programs.

Published
2024
Full Text
View/download PDF

31. Increased Serum Prolactin and Excessive Daytime Sleepiness: An Attempt of Proof-of-Concept Study.

Author

Mogavero, Maria, Cosentino, Filomena, Lanuzza, Bartolo, Tripodi, Mariangela, Lanza, Giuseppe, Aricò, Debora, DelRosso, Lourdes, Pizza, Fabio, Plazzi, Giuseppe, and Ferri, Raffaele

Subjects
comorbidity, excessive daytime sleepiness, hypersomnia, observational study, prolactin, sleep disorders
Abstract

The objectives of this study were: (1) to identify subjects with hyperprolactinemia in a clinical sample of patients; (2) to compare the neurologic, psychiatric, and sleep conditions found in patients subgrouped by excessive daytime sleepiness (EDS) and hyperprolactinemia; and (3) to identify patients with hyperprolactinemia and EDS not supported by the presence of any other neurologic, psychiatric, or sleep disorder, or substance/medication use. A retrospective chart review of inpatients was carried out in order to identify all patients in whom the prolactin (PRL) serum levels were determined. A total of 130 subjects were retrieved: 55 had increased levels of PRL, while the remaining 75 participants had normal PRL levels. EDS was reported by 32 (58.2%) participants with increased PRL and 34 (45.3%) with normal PRL. Obstructive sleep apnea or other sleep or neurologic/psychiatric conditions could explain EDS in all participants with normal PRL. Among subjects with increased PRL, eight had no other neurologic/psychiatric or sleep disorder (or drug) potentially causing EDS; these participants, at polysomnography, had time in bed, sleep period time, and total sleep time longer than those with EDS associated to another condition. These findings can be considered as a preliminary indication of a role of hyperprolactinemia in EDS and represent a basis for future controlled studies able to test this hypothesis in a reliable, objective, and methodologically more appropriate way.

Published
2021

37. Fertility specialists’ views, behavior, and attitudes towards the use of endometrial scratching in Italy

Author

Palomba, Stefano, Carone, Domenico, Vitagliano, Amerigo, Costanzi, Flavia, Fracassi, Alice, Russo, Tiziana, Del Negro, Serena, Biello, Altiero, Di Filippo, Aldo, Mangiacasale, Antonio, Monaco, Antonio, Ranieri, Antonio, Ermini, Beatrice, Barba, Bruno Francesco, Castello, Claudio, Di Guardo, Federica, Pastorella, Francesco, Bernasconi, Elena, Tricarico, Ezio Michele, Filippi, Francesca, Polsinelli, Francesco, Monte, Giuseppe Lo, Sosa Fernandez, Loredana M., Galletta, Marco, Giardina, Paolo, Totaro, Pasquale, Laganara, Roberto, Liguori, Roberto, Buccheri, Matteo, Montanino Oliva, Mario, Piscopo, Rosita, Iuliano, Assunta, Innantuoni, Nicola, Romanello, Irene, Sinatra, Francesco, Liprino, Annalisa, Thiella, Roberto, Tiezzi, Alessandra, Bartolotti, Tiziana, Tomasi, Alessandra, Finocchiaro, Valeria, Thiella, Mario, Fuggetta, Giuseppa, Messineo, Sebastiano, Isabella, Francesco, Tripodi, Marcello, Iaccarino, Stefania, La Sala, Giovanni Battista, Papaleo, Enrico, Caserta, Donatella, Marci, Roberto, Somigliana, Edgardo, and Guglielmino, Antonino

Published
2023
Full Text
View/download PDF

41. Targeted inhibition of the methyltransferase SETD8 synergizes with the Wee1 inhibitor adavosertib in restraining glioblastoma growth

Author

Della Monica, Rosa, Buonaiuto, Michela, Cuomo, Mariella, Pagano, Cristina, Trio, Federica, Costabile, Davide, de Riso, Giulia, Cicala, Francesca Sveva, Raia, Maddalena, Franca, Raduan Ahmed, Del Basso De Caro, Marialaura, Sorrentino, Domenico, Navarra, Giovanna, Coppola, Laura, Tripodi, Lorella, Pastore, Lucio, Hench, Juergen, Frank, Stephan, Schonauer, Claudio, Catapano, Giuseppe, Bifulco, Maurizio, Chiariotti, Lorenzo, and Visconti, Roberta

Published
2023
Full Text
View/download PDF

42. Dominant bee species and floral abundance drive parasite temporal dynamics in plant-pollinator communities.

Author

Graystock, Peter, Ng, Wee, Parks, Kyle, Tripodi, Amber, Muñiz, Paige, Fersch, Ashley, Myers, Christopher, McFrederick, Quinn, and McArt, Scott

Subjects
Animals, Bees, Nosema, Parasites, Plants, Residence Characteristics
Abstract

Pollinator reductions can leave communities less diverse and potentially at increased risk of infectious diseases. Species-rich plant and bee communities have high species turnover, making the study of disease dynamics challenging. To address how temporal dynamics shape parasite prevalence in plant and bee communities, we screened >5,000 bees and flowers over an entire growing season for five common bee microparasites (Nosema ceranae, Nosema bombi, Crithidia bombi, Crithidia expoeki and neogregarines). Over 110 bee species and 89 flower species were screened, revealing that 42% of bee species (12.2% individual bees) and 70% of flower species (8.7% individual flowers) had at least one parasite in or on them, respectively. Some common flowers (for example, Lychnis flos-cuculi) harboured multiple parasite species whilst others (for example, Lythrum salicaria) had few. Significant temporal variation of parasite prevalence in bees was linked to bee diversity, bee and flower abundance and community composition. Specifically, we found that bee communities had the highest prevalence late in the season, when social bees (Bombus spp. and Apis mellifera) were dominant and bee diversity was lowest. Conversely, prevalence on flowers was lowest late in the season when floral abundance was highest. Thus turnover in the bee community impacted community-wide prevalence, and turnover in the plant community impacted when parasite transmission was likely to occur at flowers. These results imply that efforts to improve bee health will benefit from the promotion of high floral numbers to reduce transmission risk, maintaining bee diversity to dilute parasites and monitoring the abundance of dominant competent hosts.

Published
2020

49. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses

Author

Ovadia, Caroline, Seed, Paul T, Sklavounos, Alexandros, Geenes, Victoria, Di Illio, Chiara, Chambers, Jenny, Kohari, Katherine, Bacq, Yannick, Bozkurt, Nuray, Brun-Furrer, Romana, Bull, Laura, Estiú, Maria C, Grymowicz, Monika, Gunaydin, Berrin, Hague, William M, Haslinger, Christian, Hu, Yayi, Kawakita, Tetsuya, Kebapcilar, Ayse G, Kebapcilar, Levent, Kondrackienė, Jūratė, Koster, Maria PH, Kowalska-Kańka, Aneta, Kupčinskas, Limas, Lee, Richard H, Locatelli, Anna, Macias, Rocio IR, Marschall, Hanns-Ulrich, Oudijk, Martijn A, Raz, Yael, Rimon, Eli, Shan, Dan, Shao, Yong, Tribe, Rachel, Tripodi, Valeria, Abide, Cigdem Yayla, Yenidede, Ilter, Thornton, Jim G, Chappell, Lucy C, and Williamson, Catherine

Subjects
Perinatal Period - Conditions Originating in Perinatal Period, Pediatric, Digestive Diseases, Reproductive health and childbirth, Good Health and Well Being, Alanine Transaminase, Aspartate Aminotransferases, Bile Acids and Salts, Bilirubin, Biomarkers, Case-Control Studies, Cholestasis, Intrahepatic, Cohort Studies, Female, Humans, Infant, Newborn, Perinatal Death, Pregnancy, Pregnancy Complications, Premature Birth, ROC Curve, Randomized Controlled Trials as Topic, Risk Factors, Stillbirth, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundIntrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear. We aimed to quantify the adverse perinatal effects of intrahepatic cholestasis of pregnancy in women with increased serum bile acid concentrations and determine whether elevated bile acid concentrations were associated with the risk of stillbirth and preterm birth.MethodsWe did a systematic review by searching PubMed, Web of Science, and Embase databases for studies published from database inception to June 1, 2018, reporting perinatal outcomes for women with intrahepatic cholestasis of pregnancy when serum bile acid concentrations were available. Inclusion criteria were studies defining intrahepatic cholestasis of pregnancy based upon pruritus and elevated serum bile acid concentrations, with or without raised liver aminotransferase concentrations. Eligible studies were case-control, cohort, and population-based studies, and randomised controlled trials, with at least 30 participants, and that reported bile acid concentrations and perinatal outcomes. Studies at potential higher risk of reporter bias were excluded, including case reports, studies not comprising cohorts, or successive cases seen in a unit; we also excluded studies with high risk of bias from groups selected (eg, a subgroup of babies with poor outcomes were explicitly excluded), conference abstracts, and Letters to the Editor without clear peer review. We also included unpublished data from two UK hospitals. We did a random effects meta-analysis to determine risk of adverse perinatal outcomes. Aggregate data for maternal and perinatal outcomes were extracted from case-control studies, and individual patient data (IPD) were requested from study authors for all types of study (as no control group was required for the IPD analysis) to assess associations between biochemical markers and adverse outcomes using logistic and stepwise logistic regression. This study is registered with PROSPERO, number CRD42017069134.FindingsWe assessed 109 full-text articles, of which 23 studies were eligible for the aggregate data meta-analysis (5557 intrahepatic cholestasis of pregnancy cases and 165 136 controls), and 27 provided IPD (5269 intrahepatic cholestasis of pregnancy cases). Stillbirth occurred in 45 (0·83%) of 4936 intrahepatic cholestasis of pregnancy cases and 519 (0·32%) of 163 947 control pregnancies (odds ratio [OR] 1·46 [95% CI 0·73-2·89]; I2=59·8%). In singleton pregnancies, stillbirth was associated with maximum total bile acid concentration (area under the receiver operating characteristic curve [ROC AUC]) 0·83 [95% CI 0·74-0·92]), but not alanine aminotransferase (ROC AUC 0·46 [0·35-0·57]). For singleton pregnancies, the prevalence of stillbirth was three (0·13%; 95% CI 0·02-0·38) of 2310 intrahepatic cholestasis of pregnancy cases in women with serum total bile acids of less than 40 μmol/L versus four (0·28%; 0·08-0·72) of 1412 cases with total bile acids of 40-99 μmol/L (hazard ratio [HR] 2·35 [95% CI 0·52-10·50]; p=0·26), and versus 18 (3·44%; 2·05-5·37) of 524 cases for bile acids of 100 μmol/L or more (HR 30·50 [8·83-105·30]; p

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results