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Network dismantling, which aims at finding the optimal node sequence whose removal will dismantle the whole network effectively, remains as a hot topic in the research area of complex networks and systems. In this study, an improved network dismantling strategy based on ant-colony optimization algorithm is proposed. Through large quantities of numerical simulations, compared with several classical network dismantling methods, the effectiveness of the proposed strategy is verified. Current results can provide a new perspective for us to comprehend the complexity and optimization of complex networked systems. [ABSTRACT FROM AUTHOR]

We aimed to determine the molecular characteristics of carbapenem-resistant Pseudomonas aeruginosa strains 18081308 and 18083286, which were isolated from the urine and the sputum of two Chinese patients, respectively. Additionally, we conducted a comparative analysis between Tn6411 carrying blaIMP-1 in strain 18083286 and transposons from the same family available in GenBank. Bacterial genome sequencing was carried out on strains 18081308 and 18083286 to obtain their whole genome sequence. Average nucleotide identity (ANI) was used for their precise species identification. Serotyping and multilocus sequence typing were performed. Furthermore, the acquired drug resistance genes of these strains were identified. The carbapenem-resistant P. aeruginosa strains isolated in the present study were of sequence type ST865 and serotype O6. They all carried the same resistance genes (aacC2, tmrB, and blaIMP-1). Tn6411, a Tn7-like transposon carrying blaIMP-1, was found in strain 18083286 by single molecule real time (SMRT) sequencing. We also identified the presence of this transposon sequence in other chromosomes of P. aeruginosa and plasmids carried by Acinetobacter spp. in GenBank, indicating the necessity for heightening attention to the potential transferability of this transposon. [ABSTRACT FROM AUTHOR]

(1) Background: Antibiotic resistance in bacteria is an urgent global threat to public health. Migratory birds can acquire antibiotic-resistant and pathogenic bacteria from the environment or through contact with each other and spread them over long distances. The objectives of this study were to explore the relationship between migratory birds and the transmission of drug-resistant pathogenic Escherichia coli. (2) Methods: Faeces and swab samples from migratory birds were collected for isolating E. coli on the Inner Mongolia Plateau of northern China from 2018 to 2023. The resistant phenotypes and spectra of isolates were determined using a BD Phoenix 100 System. Conjugation assays were performed on extended-spectrum β-lactamase (ESBL)-producing strains, and the genomes of multidrug-resistant (MDR) and ESBL-producing isolates were sequenced and analysed. (3) Results: Overall, 179 isolates were antibiotic-resistant, with 49.7% MDR and 14.0% ESBL. Plasmids were successfully transferred from 32% of ESBL-producing strains. Genome sequencing analysis of 91 MDR E. coli strains identified 57 acquired resistance genes of 13 classes, and extraintestinal pathogenic E. coli and avian pathogenic E. coli accounted for 26.4% and 9.9%, respectively. There were 52 serotypes and 54 sequence types (STs), including ST48 (4.4%), ST69 (4.4%), ST131 (2.2%) and ST10 (2.2%). The international high-risk clonal strains ST131 and ST10 primarily carried blaCTX-M-27 and blaTEM-176. (4) Conclusions: There is a high prevalence of multidrug-resistant virulent E. coli in migratory birds on the Inner Mongolian Plateau. This indicates a risk of intercontinental transmission from migratory birds to livestock and humans. [ABSTRACT FROM AUTHOR]

Aim: This study aims to identify and synthesize available research reporting parental mental health outcomes related to contact with a stillborn baby. Background: Stillbirth is devastating events for parents. The effects of contact with the stillborn baby on parental mental health are uncertain. Methods: This was a systematic review and meta‐analysis carried out by searching six international electronic databases including PubMed, EMBASE, Cochrane, Web of Science, PsycINFO and CNKI databases from inception to 15 January 2023. Review Manager software was used for data analysis. Results: Ten studies were included (n = 3974). Contact with a stillborn baby increased the risks of anxiety, depression and post‐traumatic stress disorder in the short term and increased the risks of anxiety and post‐traumatic stress disorder in the long term. Parents who had contact with a stillborn baby were more satisfied with their decision. Subgroup analysis showed that seeing a stillborn baby had no significant effect on anxiety or depression, but holding a stillborn baby increased the risks of anxiety. Conclusions: Caregivers should respect the parents' decision on whether to have contact with the stillborn baby and provide parents with continuous information, emotional and behavioural support after they have contact with stillborn babies. Summary statement: What is already known about this topic? Stillbirth is a tragic event for parents and the extended families and can trigger intense grief and devastating psychosocial symptoms.Although some studies have been conducted to investigate the effect of contact with the stillborn baby on parental mental health, there is no consensus on the effectiveness of contact with the stillborn baby. What this paper adds? Contact with stillborn baby, particularly holding a stillborn baby, may increase the risk of harm to parental mental health.Parents were more satisfied with their decision to have contact with a stillborn baby rather than no contact with their stillborn baby. The implications of this paper: This study may provide evidence for managers and caregivers about the development of guidelines for contact with a stillborn baby and promote parental mental health. [ABSTRACT FROM AUTHOR]

Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) infection is a serious problem in hospitals worldwide. We monitored a tertiary hospital in Changchun, Jilin Province, China, and found that CRKP was the major species among the carbapenem-resistant isolates in sewage. Subsequently, we evaluated the drug susceptibility, resistance genes, virulence genes, outer pore membrane protein-related genes (OmpK35 & OmpK 36), multi-locus sequence typing and replicons, biofilm formation capabilities, and resistance to chlorine-containing disinfectants among KP isolates. Identification of drug sensitivity, multiple resistance profiles were observed including 77 (82.80%) multidrug resistant (MDR), 16 (17.20%) extensive drug resistant (XDR). Some antibiotic resistance genes were detected, the most prevalent carbapenemase gene was blaKPC, and 16 resistance genes were associated with other antibiotics. In addition, 3 (3.23%) CRKP isolates demonstrated loss of OmpK-35 and 2 (2.15%) demonstrated loss of OmpK-36. In the detection of multi-locus sequence typing (MLST), 11 ST11 isolates carried virulence genes. The most common replicon type was IncFII. Biofilm-forming capabilities were demonstrated by 68.8% of the isolates, all of which were resistant to chlorine-containing disinfectants. The results of the study showed that antibiotic-resistant isolates, especially CRKP, could resist disinfectants in hospital wastewater, and improper treatment of hospital wastewater may lead to the spread of drug-resistant bacteria and their genes. Thus, these bacteria must be eliminated before being discharged into the municipal sewage system. [ABSTRACT FROM AUTHOR]

Aims: The study aimed to present a broad overview of the research conducted and to synthesize evidence of the utility of nonpharmacological interventions for pain management in medical and surgical abortions. Background: High‐quality care for medical and surgical abortion requires pain to be managed effectively. However, women reported low satisfaction with pain management in abortion care. Design: A scoping review design was employed. Data sources No date limit was set. PubMed, Cochrane Library, EMBASE, Web of Science, CINAHL, PsycINFO, ProQuest and Scopus were searched in April 2021. Review methods: Arksey and O'Malley's framework was used. The Preferred Reporting Items for Systematic reviews and Meta‐analysis extension‐Scoping Reviews was followed. Results: Fifteen studies were included. The results revealed that support interventions, music therapy, acupoint stimulation and hypnotic analgesia were nonpharmacological interventions used to decrease abortion pain. Conclusions: Clinical nurses, nurse managers and policymakers should attach full importance to the pain management in abortion and may use the study findings to guide the pain management practice. Summary statement: What is already known about this topic? Women reported maximum pain levels and low satisfaction with the current pain management of abortion.The quality of abortion care that women receive may impact their psychological well‐being.Nursing professionals lacked professional knowledge and awareness of pain management, which may impede the provision of high‐quality of abortion care. What this paper adds? Among the selected 15 studies, nonpharmacological pain management interventions included support interventions, music therapy, acupoint stimulation and hypnotic analgesia.Useful pain assessment tools, effective pain treatment and sufficient professional attendance are important components for relieving pain in abortion.Outcomes of pain, anxiety and satisfaction could be adopted for effectiveness evaluation. The implications of this paper Nursing professionals may use these findings to ensure better pain management in abortion care for women.Meta‐analysis is needed to clarify the respective effectiveness of nonpharmacological interventions on pain, psychological outcomes, satisfaction and analgesic consumption.Relevant pain management training should be offered to nursing professionals in abortion care. [ABSTRACT FROM AUTHOR]

Purpose: To estimate the prevalence of posttraumatic stress disorder (PTSD) among parents in cases of fetal abnormalities and associated factors. Design and Methods: A cross‐sectional study. The study sample comprised 169 couples who experienced fetal abnormalities. Findings: We observed a high prevalence of PTSD. Fathers had similar levels of PTSD to those of mothers. Social support was an important protective factor against parental PTSD. In addition, a negative psychological reaction to the loss of a child in either the father or the mother affects the other spouse. Practice Implications: This study emphasizes recognizing the importance of social support and of psychological interactions between mothers and fathers in PTSD intervention for parents. [ABSTRACT FROM AUTHOR]