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Start Over Author "Stefanie Keil" Publication Type Academic Journals
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1. Dendrimers of Vaccines Consisting of Tumor-Associated Glycopeptide Antigens and T Cell Epitope Peptides.

Author

Stefanie Keil

Subjects
*DENDRIMERS, *VACCINES, *GLYCOPEPTIDES, *TUMOR antigens, *T cells, *EPITOPES, *LYSINE
Abstract

According to the principle of multiple antigen presentation (MAP), a di-lysyl lysine core was used for the synthesis of tetramers of a glycododecapeptide antigen from the tandem-repeat sequence of the tumor-associated mucin, MUC1, which carries a sialyl T N-antigen saccharide side chain. The methodology was extended to the analogous construction of a tetrameric vaccine consisting of a T cell epitope from tetanus toxoid and the sialyl T N-glycododecapeptide of MUC1. [ABSTRACT FROM AUTHOR]

Published
2009
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