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Your search keyword '"Smits, Anke"' showing total 310 results
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310 results on '"Smits, Anke"'

1. Better stoma care using the Stoma App: does it help? A first randomized double-blind clinical trial on the effect of mobile healthcare on quality of life in stoma patients

Author

van der Storm, Sebastiaan L., Consten, Esther C. J., Govaert, Marc J. P. M., Tuynman, Jurriaan B., Oosterling, Steven J., Grotenhuis, Brechtje A., Smits, Anke B., Marsman, Hendrik A., van Rossem, Charles C., van Duyn, Eino B., de Nes, Lindsey C. F., Verdaasdonk, Emiel, de Vries Reilingh, Tammo S., Vening, Wouter, Bemelman, Willem A., and Schijven, Marlies P.

Published
2024
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2. Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment

Author

Aalbers, Arend G.J., van Aalten, Susanna M., Amelung, Femke J., Ankersmit, Marjolein, Antonisse, Imogeen E., Ashruf, Jesse F., Aukema, Tjeerd S., Avenarius, Henk, Bahadoer, Renu R., Bakers, Frans C.H., Bakker, Ilsalien S., Bangert, Fleur, Barendse, Renée M., Beekhuis, Heleen M.D., Beets, Geerard L., Bemelman, Willem A., Berbée, Maaike, de Bie, Shira H., Bisschops, Robert H.C., Blok, Robin D., van Bockel, Liselotte W., Boer, Anniek H., den Boer, Frank C., Boerma, Evert-Jan G., Boogerd, Leonora S.F., Borstlap, Jaap, Borstlap, Wernard A.A., Bouwman, Johanna E., Braak, Sicco J., Braat, Manon N.G.J.A., Bradshaw, Jennifer, Brandsma, Amarins T.A., van Breest Smallenburg, Vivian, van den Broek, Wim T., van der Burg, Sjirk W., Burger, Jacobus W.A., Burghgraef, Thijs A., ten Cate, David W.G., Ceha, Heleen M., Cnossen, Jeltsje S., Coebergh van den Braak, Robert R.J., Consten, Esther C.J., Corver, Maaike, Crolla, Rogier M.P.H., Curutchet, Sam, Daniëls-Gooszen, Alette W., Davids, Paul H.P., Dekker, Emmelie N., Dekker, Jan Willem T., Demirkiran, Ahmet, Derksen, Tyche, Diederik, Arjen L., Dinaux, Anne M., Dogan, Kemal, van Dop, Ilse M., Droogh-de Greve, Kitty E., Duijsens, Hanneke M.H., Dunker, Michalda S., Duyck, Johan, van Duyn, Eino B., van Egdom, Laurentine S.E., Eijlers, Bram, El-Massoudi, Youssef, van Elderen, Saskia, Emmen, Anouk M.L.H., Engelbrecht, Marc, van Erp, Anne C., van Essen, Jeroen A., Fabry, Hans F.J., Fassaert, Thomas, Feitsma, Eline A., Feshtali, Shirin S., Frietman, Bas, Furnée, Edgar J.B., van Geel, Anne M., Geijsen, Elisabeth D., van Geloven, Anna A.W., Gerhards, Michael F., Gielkens, Hugo, van Gils, Renza A.H., Goense, Lucas, Govaert, Marc J.P.M., van Grevenstein, Wilhelmina M.U., Joline de Groof, E., de Groot, Irene, de Haas, Robbert J., Hakkenbrak, Nadia A.G., den Hartogh, Mariska D., Heesink, Vera, Heikens, Joost T., Hendriksen, Ellen M., van den Hoek, Sjoerd, van der Hoeven, Erik J.R.J., Hoff, Christiaan, Hogewoning, Anna, Hogewoning, Cornelis R.C., Hoogendoorn, Stefan, van Hoorn, Francois, van der Hul, René L., van Hulst, Rieke, Imani, Farshad, Inberg, Bas, Intven, Martijn P.W., Janssen, Pedro, de Jong, Chris E.J., Jonkers, Jacoline, Jou-Valencia, Daniela, Keizers, Bas, Ketelaers, Stijn H.J., Knöps, Eva, van Koeverden, Sebastiaan, Kok, Sylvia, Kolderman, Stephanie E.M., de Korte, Fleur I., Kortekaas, Robert T.J., Korving, Julie C., Koster, Ingrid M., Krdzalic, Jasenko, Krielen, Pepijn, Kroese, Leonard F., Krul, Eveline J.T., Lahuis, Derk H.H., Lamme, Bas, van Landeghem, An A.G., Leijtens, Jeroen W.A., Leseman-Hoogenboom, Mathilde M., de Lijster, Manou S., Marsman, Martijn S., Martens, MilouH., Masselink, Ilse, van der Meij, Wout, Meijnen, Philip, Melenhorst, Jarno, de Mey, Dietrich J.L., Moelker-Galuzina, Julia, Morsink, Linda, Mulder, Erik J., Muller, Karin, Musters, Gijsbert D., Neijenhuis, Peter A., de Nes, Lindsey C.F., Nielen, M., van den Nieuwboer, Jan B.J., Nieuwenhuis, Jonanne F., Nonner, Joost, Noordman, Bo J., Nordkamp, Stefi, Olthof, Pim B., Oosterling, Steven J., Ootes, Daan, Oppedijk, Vera, Ott, Pieter, Paulusma, Ida, Peeters, Koen C.M.J., Pereboom, Ilona T.A., Peringa, Jan, Pironet, Zoë, Plate, Joost D.J., Polat, Fatih, Poodt, Ingrid G.M., Posma, Lisanne A.E., Prette, Jeroen F., Pultrum, Bareld B., Qaderi, Seyed M., van Rees, Jan M., Renger, Rutger-Jan, Rombouts, Anouk J.M., Roosen, Lodewijk J., Roskott-ten Brinke, Ellen A., Rothbarth, Joost, Rouw, Dennis B., Rozema, Tom, Rütten, Heidi, Rutten, Harm J.T., van der Sande, Marit E., Schaafsma, Boudewijn E., Schasfoort, Renske A., Scheurkogel, Merel M., Schouten van der Velden, Arjan P., Schreurs, Wilhelmina H., Schuivens, Puck M.E., Sietses, Colin, Simons, Petra C.G., Slob, Marjan J., Slooter, Gerrit D., van der Sluis, Martsje, Smalbroek, Bo P., Smits, Anke B., Spillenaar-Bilgen, Ernst J., Spruit, Patty H., Stam, Tanja C., Stoker, Jaap, Talsma, Aaldert K., Temmink, Sofieke J.D., The, G.Y. Mireille, Tielbeek, Jeroen A.W., van Tilborg, Aukje A.J.M., van Tilborg, Fiek, van Trier, Dorothée, Tuynman, Jurriaan B., van der Valk, Maxime J.M., Vanhooymissen, Inge J.S., Vasbinder, G. Boudewijn C., Veeken, Cornelis J., Velema, Laura A., van de Ven, Anthony W.H., Verdaasdonk, Emiel G.G., Verduin, Wouter M., Verhagen, Tim, Verheijen, Paul M., Vermaas, Maarten, Verrijssen, An-Sofie E., Verschuur, Anna V.D., Schaik, Harmke Verwoerd-van, Vliegen, Roy F.A., Voets, Sophie, Vogelaar, F. Jeroen, Vogelij, Clementine L.A., Vos-Westerman, Johanna, de Vries, Marianne, Vroemen, Joy C., van Vugt, Bas S.T., Wegdam, Johannes A., van Wely, Bob J., Westerterp, Marinke, van Westerveld, Paul P., van Westreenen, Henderik L., Wijma, Allard G., de Wilt, Johannes H.W., de Wit, Bart W.K., Wit, Fennie, Woensdregt, Karlijn, van Woerden, Victor, van der Wolf, Floor S.W., van der Wolk, Sander, Wybenga, Johannes M., van der Zaag, Edwin S., Zamaray, Bobby, Zandvoort, Herman J.A., van der Zee, Dennis, Zeilstra, Annette P., Zheng, Kang J., Zimmerman, David D.E., Zorgdrager, Marcel, Geffen, Eline G.M. van, Nederend, Joost, Sluckin, Tania C., Hazen, Sanne-Marije J.A., Horsthuis, Karin, Beets-Tan, Regina G.H., Marijnen, Corrie A.M., Tanis, Pieter J., and Kusters, Miranda

Published
2024
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3. Evaluation of National Surgical Practice for Lateral Lymph Nodes in Rectal Cancer in an Untrained Setting

Author

Sluckin, Tania C., Hazen, Sanne-Marije J. A., Horsthuis, Karin, Beets-Tan, Regina G. H., Aalbers, Arend G. J., Beets, Geerard L., Boerma, Evert-Jan G., Borstlap, Jaap, van Breest Smallenburg, Vivian, Burger, Jacobus W. A., Crolla, Rogier M. P. H., Daniëls-Gooszen, Alette W., Davids, Paul H. P., Dunker, Michalda S., Fabry, Hans F. J., Furnée, Edgar J. B., van Gils, Renza A. H., de Haas, Robbert J., Hoogendoorn, Stefan, van Koeverden, Sebastiaan, de Korte, Fleur I., Oosterling, Steven J., Peeters, Koen C. M. J., Posma, Lisanne A. E., Pultrum, Bareld B., Rothbarth, Joost, Rutten, Harm J. T., Schasfoort, Renske A., Schreurs, Wilhelmina H., Simons, Petra C. G., Smits, Anke B., Talsma, Aaldert K., The, G. Y. Mireille, van Tilborg, Fiek, Tuynman, Jurriaan B., Vanhooymissen, Inge J. S., van de Ven, Anthony W. H., Verdaasdonk, Emiel G. G., Vermaas, Maarten, Vliegen, Roy F. A., Vogelaar, F. Jeroen, de Vries, Marianne, Vroemen, Joy C., van Vugt, Sebastiaan T., Westerterp, Marinke, van Westreenen, Henderik L., de Wilt, Johannes H. W., van der Zaag, Edwin S., Zimmerman, David D. E., Marijnen, Corrie A. M., Tanis, Pieter J., and Kusters, Miranda

Published
2023
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6. ASO Visual Abstract: Evaluation of National Surgical Practice for Lateral Lymph Nodes in Rectal Cancer in an Untrained Setting

Author

Sluckin, Tania C., Hazen, Sanne-Marije J. A., Horsthuis, Karin, Beets-Tan, Regina G. H., Aalbers, Arend G. J., Beets, Geerard L., Boerma, Evert-Jan G., Borstlap, Jaap, van Breest Smallenburg, Vivian, Burger, Jacobus W. A., Crolla, Rogier M. P. H., Daniëls-Gooszen, Alette W., Davids, Paul H. P., Dunker, Michalda S., Fabry, Hans F. J., Furnée, Edgar J. B., van Gils, Renza A. H., de Haas, Robbert J., Hoogendoorn, Stefan, van Koeverden, Sebastiaan, de Korte, Fleur I., Oosterling, Steven J., Peeters, Koen C. M. J., Posma, Lisanne A. E., Pultrum, Bareld B., Rothbarth, Joost, Rutten, Harm J. T., Schasfoort, Renske A., Schreurs, Wilhelmina H., Simons, Petra C. G., Smits, Anke B., Talsma, Aaldert K., The, G. Y. Mireille, van Tilborg, Fiek, Tuynman, Jurriaan B., Vanhooymissen, Inge J., van de Ven, Anthony W. H., Verdaasdonk, Emiel G. G., Vermaas, Maarten, Vliegen, Roy F. A., Vogelaar, F. Jeroen, de Vries, Marianne, Vroemen, Joy C., van Vugt, Sebastiaan T., Westerterp, Marinke, van Westreenen, Henderik L., de Wilt, Johannes H. W., van der Zaag, Edwin S., Zimmerman, David D. E., Marijnen, Corrie A. M., Tanis, Pieter J., and Kusters, Miranda

Published
2023
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10. Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy?

Author

Vrede, Stephanie W., Donkers, Hannah, Reijnen, Casper, Smits, Anke, Visser, Nicole C.M., Geomini, Peggy M., Ngo, Huy, van Hamont, Dennis, Pijlman, Brenda M., Vos, Maria Caroline, Snijders, Marc P.L.M., Kruitwagen, Roy, Bekkers, Ruud L.M., Galaal, Khadra, and Pijnenborg, Johanna M.A.

Abstract

Background: In endometrial cancer (EC), preoperative anaemia, thrombocytosis and leucocytosis appear to be associated with worse prognosis. It remains unclear whether these parameters solely reflect tumour aggressiveness, or also impact response to adjuvant treatment. Therefore, our primary aim is to evaluate the prognostic relevance of anaemia, thrombocytosis and leucocytosis on survival in EC. Secondary, to explore their predictive relevance in response to radiotherapy in EC. Methods: A retrospective multicentre cohort study was performed within 10 hospitals. Preoperative haematological parameters were defined as: Anaemia – haemoglobin <7.45 mmol/L (<12 g/Dl), thrombocytosis – platelets >400 × 109 platelets/L, leucocytosis – leukocytes >10 × 109/L. The relationship of haematological parameters with clinicopathological characteristics, ESGO/ESTRO/ESP risk groups and survival were evaluated. Furthermore, the predictive value of haematological parameters was determined on the overall response to adjuvant radiotherapy and for the ESGO/ESTRO/ESP intermediate-risk group solely receiving radiotherapy. Results: A total of 894 patients were included with a median follow-up of 4.5 years. Anaemia was present in 103 (11.5%), thrombocytosis in 79 (8.8%) and leucocytosis in 114 (12.7%) patients. The presence of anaemia or thrombocytosis was significantly associated with ESGO/ESTRO/ESP high-risk (respectively, P = 0.002 and P = 0.041). In the entire cohort, anaemia remained independently associated with decreased disease-specific survival (HR 2.31, 95% CI (1.19–4.50), P = 0.013) after adjusting for age, the abnormal haematological parameters and ESGO/ESTRO/ESP risk groups. In patients that were treated with adjuvant radiotherapy (n = 239), anaemia was associated with significant reduced 5-year disease-specific and recurrence-free survival (P = 0.005 and P = 0.025, respectively). In ESGO/ESTRO/ESP intermediate risk patients that received solely vaginal brachytherapy (n = 74), anaemia was associated with reduced disease-specific survival (P = 0.041). Conclusions: Current data demonstrate the importance of preoperative anaemia as independent prognostic factor in patients with EC. Moreover, anaemia seems to be associated with reduced response to radiotherapy. Prospective validation in a larger study cohort is needed to verify anaemia as predictive biomarker for radiotherapy. What is already known on this subject? In endometrial cancer, preoperative abnormal haematological parameters like, anaemia, thrombocytosis and leucocytosis appears to be associated with FIGO advanced-stage and unfavourable outcome. What do the results of this study add? It remains unclear whether anaemia, thrombocytosis or leucocytosis solely reflecting worse prognosis by advanced tumour stage, or also impact response to adjuvant treatment. Current data demonstrate that anaemia is independent associated with decreased disease-specific survival and anaemia seems related with reduced response to radiotherapy and in specific to vaginal brachytherapy in ESGO/ESTRO/ESP intermediate risk patients. What are the implications of these findings for clinical practice and/or further research? Specific applied adjuvant treatment is needed if patients with anaemia have a reduced response to radiotherapy in EC. Prospective validation in a larger study cohort is required to verify anaemia as predictive biomarker for radiotherapy and to further evaluate the prognostic/predictive impact of anaemia in addition to the molecular subgroups. PLAIN LANGUAGE SUMMARY: In this study we focused on three specific blood values before surgery to predict survival outcomes in endometrial cancer patients: low haemoglobin (anaemia), high platelet count (thrombocytosis) and high white blood cell count (leucocytosis). We studied 894 patients with endometrial cancer over about 4.5 years, in which 11.5% had anaemia, 8.8% thrombocytosis and 12.7% leucocytosis. Anaemia was linked to a lower chance of surviving endometrial cancer, even after we considering patients' age, thrombocytosis, leucocytosis and the endometrial cancer risk classification groups. In patients who received radiotherapy after surgery (293 patients), anaemia was linked to a lower change of surviving and cancer coming back within 5 years. In patients within the intermediate endometrial cancer risk classification group who only received specific radiotherapy (74 patients), anaemia was even linked with lower chance of survival. In conclusion, anaemia is an important factor in predicting endometrial cancer outcomes, and it might also make radiotherapy less effective for some patients. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Frailty and health related quality of life three months after non-metastatic colorectal cancer diagnosis in older patients: A multi-centre prospective observational study

Author

van der Vlies, Ellen, Vernooij, Lisette M., Hamaker, Marije E., van der Velden, Ankie M.T., Smits, Marianne, Intven, Martijn P.W., van Dodewaard, Joyce M., Takkenberg, Marijn, Vink, Geraldine R., Smits, Anke B., Bos, Willem Jan W., van Dongen, Eric P.A., Los, Maartje, and Noordzij, Peter G.

Published
2022
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13. Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

Author

Qiao, Xiaohang, van der Zanden, Sabina Y., Wander, Dennis P. A., Borràs, Daniel M., Song, Ji-Ying, Li, Xiaoyang, van Duikeren, Suzanne, van Gils, Noortje, Rutten, Arjo, van Herwaarden, Tessa, van Tellingen, Olaf, Giacomelli, Elisa, Bellin, Milena, Orlova, Valeria, Tertoolen, Leon G. J., Gerhardt, Sophie, Akkermans, Jimmy J., Bakker, Jeroen M., Zuur, Charlotte L., Pang, Baoxu, Smits, Anke M., Mummery, Christine L., Smith, Linda, Arens, Ramon, Li, Junmin, Overkleeft, Hermen S., and Neefjes, Jacques

Published
2020

21. Total mesorectal excision in MRI-defined low rectal cancer: multicentre study comparing oncological outcomes of robotic, laparoscopic and transanal total mesorectal excision in high-volume centres.

Author

Rutgers, Marieke L, Burghgraef, Thijs A, Hol, Jeroen C, Crolla, Rogier M, Geloven, Nanette A van, Leijtens, Jeroen W, Polat, Fatih, Pronk, Apollo, Smits, Anke B, Tuyman, Jurriaan B, Verdaasdonk, Emiel G, Sietses, Colin, Consten, Esther C, and Hompes, Roel

Subjects
RECTAL surgery, RECTAL cancer, PREOPERATIVE risk factors, LAPAROSCOPIC surgery, OVERALL survival, PROGRESSION-free survival
Abstract

Background The routine use of MRI in rectal cancer treatment allows the use of a strict definition for low rectal cancer. This study aimed to compare minimally invasive total mesorectal excision in MRI-defined low rectal cancer in expert laparoscopic, transanal and robotic high-volume centres. Methods All MRI-defined low rectal cancer operated on between 2015 and 2017 in 11 Dutch centres were included. Primary outcomes were: R1 rate, total mesorectal excision quality and 3-year local recurrence and survivals (overall and disease free). Secondary outcomes included conversion rate, complications and whether there was a perioperative change in the preoperative treatment plan. Results Of 1071 eligible rectal cancers, 633 patients with low rectal cancer were identified. Quality of the total mesorectal excision specimen (P = 0.337), R1 rate (P = 0.107), conversion (P = 0.344), anastomotic leakage rate (P = 0.942), local recurrence (P = 0.809), overall survival (P = 0.436) and disease-free survival (P = 0.347) were comparable among the centres. The laparoscopic centre group had the highest rate of perioperative change in the preoperative treatment plan (10.4%), compared with robotic expert centres (5.2%) and transanal centres (2.1%), P = 0.004. The main reason for this change was stapling difficulty (43%), followed by low tumour location (29%). Multivariable analysis showed that laparoscopic surgery was the only independent risk factor for a change in the preoperative planned procedure, P = 0.024. Conclusion Centres with expertise in all three minimally invasive total mesorectal excision techniques can achieve good oncological resection in the treatment of MRI-defined low rectal cancer. However, compared with robotic expert centres and transanal centres, patients treated in laparoscopic centres have an increased risk of a change in the preoperative intended procedure due to technical limitations. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Fracture fixation in the operative management of hip fractures (FAITH): an international, multicentre, randomised controlled trial

Author

Nauth, Aaron, Creek, Aaron T., Zellar, Abby, Lawendy, Abdel-Rahman, Dowrick, Adam, Gupta, Ajay, Dadi, Akhil, van Kampen, Albert, Yee, Albert, de Vries, Alexander C., de Mol van Otterloo, Alexander, Garibaldi, Alisha, Liew, Allen, McIntyre, Allison W., Prasad, Amal Shankar, Romero, Amanda W., Rangan, Amar, Oatt, Amber, Sanghavi, Amir, Foley, Amy L., Karlsten, Anders, Dolenc, Andrea, Bucknill, Andrew, Chia, Andrew, Evans, Andrew, Gong, Andrew, Schmidt, Andrew H., Marcantonio, Andrew J., Jennings, Andrew, Ward, Angela, Khanna, Angshuman, Rai, Anil, Smits, Anke B., Horan, Annamarie D., Brekke, Anne Christine, Flynn, Annette, Duraikannan, Aravin, Stødle, Are, van Vugt, Arie B., Luther, Arlene, Zurcher, Arthur W., Jain, Arvind, Amundsen, Asgeir, Moaveni, Ash, Carr, Ashley, Sharma, Ateet, Hill, Austin D., Trommer, Axel, Rai, B. Sachidananda, Hileman, Barbara, Schreurs, Bart, Verhoeven, Bart, Barden, Benjamin B., Flatøy, Bernhard, Cleffken, Berry I., Bøe, Berthe, Perey, Bertrand, Hanusch, Birgit C., Weening, Brad, Fioole, Bram, Rijbroek, Bram, Crist, Brett D., Halliday, Brett, Peterson, Brett, Mullis, Brian, Richardson, C. Glen, Clark, Callum, Sagebien, Carlos A., van der Pol, Carmen C., Bowler, Carol, Humphrey, Catherine A., Coady, Catherine, Koppert, Cees L., Coles, Chad, Tannoury, Chadi, DePaolo, Charles J., Gayton, Chris, Herriott, Chris, Reeves, Christina, Tieszer, Christina, Dobb, Christine, Anderson, Christopher G., Sage, Claire, Cuento, Claudine, Jones, Clifford B., Bosman, Coks H.R., Linehan, Colleen, van der Hart, Cor P., Henderson, Corey, Lewis, Courtland G., Davis, Craig A., Donohue, Craig, Mauffrey, Cyril, Sundaresh, D.C., Farrell, Dana J., Whelan, Daniel B., Horwitz, Daniel, Stinner, Daniel, Viskontas, Darius, Roffey, Darren M., Alexander, David, Karges, David E., Hak, David, Johnston, David, Love, David, Wright, David M., Zamorano, David P., Goetz, David R., Sanders, David, Stephen, David, Yen, David, Bardana, Davide, Olakkengil, Davy J, Lawson, Deanna, Maddock, Deborah, Sietsema, Debra L., Pourmand, Deeba, Den Hartog, Dennis, Donegan, Derek, Heels-Ansdell, Diane, Nam, Diane, Inman, Dominic, Boyer, Dory, Li, Doug, Gibula, Douglas, Price, Dustin M., Watson, Dylan J., Hammerberg, E. Mark, Tan, Edward T.C.H., de Graaf, Eelco J.R., Vesterhus, Elise Berg, Roper, Elizabeth, Edwards, Elton, Schemitsch, Emil H., Hammacher, Eric R., Henderson, Eric R., Whatley, Erica, Torres, Erick T., Vermeulen, Erik G.J., Finn, Erin, Van Lieshout, Esther M.M., Wai, Eugene K., Bannister, Evan R., Kile, Evelyn, Theunissen, Evert B.M., Ritchie, Ewan D., Khan, Farah, Moola, Farhad, Howells, Fiona, de Nies, Frank, van der Heijden, Frank H.W.M., de Meulemeester, Frank R.A.J., Frihagen, Frede, Nilsen, Fredrik, Schmidt, G. Ben, Albers, G.H. Robert, Gudger, Garland K., Jr, Johnson, Garth, Gruen, Gary, Zohman, Gary, Sharma, Gaurav, Wood, Gavin, Tetteroo, Geert W.M., Hjorthaug, Geir, Jomaas, Geir, Donald, Geoff, Rieser, Geoffrey Ryan, Reardon, Gerald, Slobogean, Gerard P., Roukema, Gert R, Visser, Gijs A., Moatshe, Gilbert, Horner, Gillian, Rose, Glynis, Guyatt, Gordon, Chuter, Graham, Etherington, Greg, Rocca, Gregory J. Della, Ekås, Guri, Dobbin, Gwendolyn, Lemke, H. Michael, Curry, Hamish, Boxma, Han, Gissel, Hannah, Kreder, Hans, Kuiken, Hans, Brom, Hans L.F., Pape, Hans-Christoph, van der Vis, Harm M, Bedi, Harvinder, Vallier, Heather A., Brien, Heather, Silva, Heather, Newman, Heike, Viveiros, Helena, van der Hoeven, Henk, Ahn, Henry, Johal, Herman, Rijna, Herman, Stockmann, Heyn, Josaputra, Hong A., Carlisle, Hope, van der Brand, Igor, Dawson, Imro, Tarkin, Ivan, Wong, Ivan, Parr, J. Andrew, Trenholm, J. Andrew, Goslings, J. Carel, Amirault, J. David, Broderick, J. Scott, Snellen, Jaap P., Zijl, Jacco A.C., Ahn, Jaimo, Ficke, James, Irrgang, James, Powell, James, Ringler, James R., Shaer, James, Monica, James T., Biert, Jan, Bosma, Jan, Brattgjerd, Jan Egil, Frölke, Jan Paul M., Wille, Jan, Rajakumar, Janakiraman, Walker, Jane E., Baker, Janell K., Ertl, Janos P., de Vries, Jean Paul P.M., Gardeniers, Jean W.M., May, Jedediah, Yach, Jeff, Hidy, Jennifer T., Westberg, Jerald R., Hall, Jeremy A., van Mulken, Jeroen, McBeth, Jessica Cooper, Hoogendoorn, Jochem, Hoffman, Jodi M., Cherian, Joe Joseph, Tanksley, John A., Jr., Clarke-Jenssen, John, Adams, John D., Esterhai, John, Tilzey, John F., Murnaghan, John, Ketz, John P., Garfi, John S., Schwappach, John, Gorczyca, John T., Wyrick, John, Rydinge, Jonas, Foret, Jonathan L., Gross, Jonathan M., Keeve, Jonathan P., Meijer, Joost, Scheepers, Joris J.G., Baele, Joseph, O'Neil, Joseph, Cass, Joseph R., Hsu, Joseph R., Dumais, Jules, Lee, Julia, Switzer, Julie A., Agel, Julie, Richards, Justin E., Langan, Justin W., Turckan, Kahn, Pecorella, Kaili, Rai, Kamal, Aurang, Kamran, Shively, Karl, van Wessem, Karlijn, Moon, Karyn, Eke, Kate, Erwin, Katie, Milner, Katrine, Ponsen, Kees Jan, Mills, Kelli, Apostle, Kelly, Johnston, Kelly, Trask, Kelly, Strohecker, Kent, Stringfellow, Kenya, Kruse, Kevin K., III, Tetsworth, Kevin, Mitchell, Khalis, Browner, Kieran, Hemlock, Kim, Carcary, Kimberly, Jørgen Haug, Knut, Noble, Krista, Robbins, Kristin, Payton, Krystal, Jeray, Kyle J., Rubino, L. Joseph, Nastoff, Lauren A., Leffler, Lauren C., Stassen, Laurents P.S., O'Malley, Lawrence K., II, Specht, Lawrence M., Thabane, Lehana, Geeraedts, Leo M.G., Shell, Leslie E., Anderson, Linda K., Eickhoff, Linda S., Lyle, Lindsey, Pilling, Lindsey, Buckingham, Lisa, Cannada, Lisa K., Wild, Lisa M., Dulaney-Cripe, Liz, Poelhekke, Lodewijk M.S.J., Govaert, Lonneke, Ton, Lu, Kottam, Lucksy, Leenen, Luke P.H., Clipper, Lydia, Jackson, Lyle T., Hampton, Lynne, de Waal Malefijt, Maarten C., Simons, Maarten P., van der Elst, Maarten, Bronkhorst, Maarten W.G.A., Bhatia, Mahesh, Swiontkowski, Marc, Lobo, Margaret J., Swinton, Marilyn, Pirpiris, Marinis, Molund, Marius, Gichuru, Mark, Glazebrook, Mark, Harrison, Mark, Jenkins, Mark, MacLeod, Mark, de Vries, Mark R., Butler, Mark S., Nousiainen, Markku, van 't Riet, Martijne, Tynan, Martin C., Campo, Martin, Eversdijk, Martin G., Heetveld, Martin J., Richardson, Martin, Breslin, Mary, Fan, Mary, Edison, Matt, Napierala, Matthew, Knobe, Matthias, Russ, Matthias, Zomar, Mauri, de Brauw, Maurits, Esser, Max, Hurley, Meghan, Peters, Melissa E., Lorenzo, Melissa, Li, Mengnai, Archdeacon, Michael, Biddulph, Michael, Charlton, Michael, McDonald, Michael D., McKee, Michael D., Dunbar, Michael, Torchia, Michael E., Gross, Michael, Hewitt, Michael, Holt, Michael, Prayson, Michael J., Edwards, Michael J.R., Beckish, Michael L., Brennan, Michael L., Dohm, Michael P., Kain, Michael S.H., Vogt, Michelle, Yu, Michelle, Verhofstad, Michiel H.J., Segers, Michiel J.M., Siroen, Michiel P.C., Reed, Mike, Vicente, Milena R., Bruijninckx, Milko M.M., Trivedi, Mittal, Bhandari, Mohit, Moore, Molly M., Kunz, Monica, Smedsrud, Morten, Palla, Naveen, Jain, Neeraj, Out, Nico J.M., Simunovic, Nicole, Schep, Niels W.L., Müller, Oliver, Guicherit, Onno R., Van Waes, Oscar J.F., Wang, Otis, Doornebosch, Pascal G., Seuffert, Patricia, Hesketh, Patrick J., Weinrauch, Patrick, Duffy, Paul, Keller, Paul, Lafferty, Paul M., Pincus, Paul, Tornetta, Paul, III, Zalzal, Paul, McKay, Paula, Cole, Peter A., de Rooij, Peter D., Hull, Peter, Go, Peter M.N.Y.M., Patka, Peter, Siska, Peter, Weingarten, Peter, Kregor, Philip, Stahel, Philip, Stull, Philip, Wittich, Philippe, de Rijcke, Piet A.R., Oprel, Pim, Devereaux, PJ, Zhou, Qi, Lee Murphy, R., Jr., Alosky, Rachel, Clarkson, Rachel, Moon, Raely, Logishetty, Rajanikanth, Nanda, Rajesh, Sullivan, Raymond J., Snider, Rebecca G., Buckley, Richard E., Iorio, Richard, Farrugia, Richard J, Jenkinson, Richard, Laughlin, Richard, Groenendijk, Richard P.R., Gurich, Richard W., Jr, Worman, Ripley, Silvis, Rob, Haverlag, Robert, Teasdall, Robert J., Korley, Robert, McCormack, Robert, Probe, Robert, Cantu, Robert V., Huff, Roger B., Simmermacher, Rogier K.J., Peters, Rolf, Pfeifer, Roman, Liem, Ronald, Wessel, Ronald N., Verhagen, Ronald, Vuylsteke, Ronald, Leighton, Ross, McKercher, Ross, Poolman, Rudolf W., Miller, Russell, Bicknell, Ryan, Finnan, Ryan, Khan, Ryan M., Mehta, Samir, Vang, Sandy, Singh, Sanjay, Anand, Sanjeev, Anderson, Sarah A., Dawson, Sarah A., Marston, Scott B., Porter, Scott E., Watson, Scott T., Festen, Sebastiaan, Lieberman, Shane, Puloski, Shannon, Bielby, Shea A., Sprague, Sheila, Hess, Shelley, MacDonald, Shelley, Evans, Simone, Bzovsky, Sofia, Hasselund, Sondre, Lewis, Sophie, Ugland, Stein, Caminiti, Stephanie, Tanner, Stephanie L., Zielinski, Stephanie M., Shepard, Stephanie, Sems, Stephen A., Walter, Stephen D., Doig, Stephen, Finley, Stephen H., Kates, Stephen, Lindenbaum, Stephen, Kingwell, Stephen P., Csongvay, Steve, Papp, Steve, Buijk, Steven E., Rhemrev, Steven J., Hollenbeck, Steven M., van Gaalen, Steven M., Yang, Steven, Weinerman, Stuart, Subash, Lambert, Sue, Liew, Susan, Meylaerts, Sven A.G., Blokhuis, Taco J., de Vries Reilingh, Tammo S., Lona, Tarjei, Scott, Taryn, Swenson, Teresa K., Endres, Terrence J., Axelrod, Terry, van Egmond, Teun, Pace, Thomas B., Kibsgård, Thomas, Schaller, Thomas M., Ly, Thuan V., Miller, Timothy J., Weber, Timothy, Le, Toan, Oliver, Todd M., Karsten, Tom M., Borch, Tor, Hoseth, Tor Magne, Nicolaisen, Tor, Ianssen, Torben, Rutherford, Tori, Nanney, Tracy, Gervais, Trevor, Stone, Trevor, Schrickel, Tyson, Scrabeck, Tyson, Ganguly, Utsav, Naumetz, V., Frizzell, Valda, Wadey, Veronica, Jones, Vicki, Avram, Victoria, Mishra, Vimlesh, Yadav, Vineet, Arora, Vinod, Tyagi, Vivek, Borsella, Vivian, Willems, W. Jaap, Hoffman, W.H., Gofton, Wade T., Lackey, Wesley G., Ghent, Wesley, Obremskey, William, Oxner, William, Cross, William W., III, Murtha, Yvonne M., and Murdoch, Zoe

Published
2017
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29. Prevention of severe infectious complications after colorectal surgery using oral non-absorbable antimicrobial prophylaxis: results of a multicenter randomized placebo-controlled clinical trial

Author

Mulder, Tessa, Kluytmans-van den Bergh, Marjolein, Vlaminckx, Bart, Roos, Daphne, de Smet, Anne Marie, de Vos tot Nederveen Cappel, Robert, Verheijen, Paul, Brandt, Alexandra, Smits, Anke, van der Vorm, Eric, Bathoorn, Erik, van Etten, Boudewijn, Veenemans, Jacobien, Weersink, Annemarie, Vos, Margreet, van ’t Veer, Nils, Nikolakopoulos, Stavros, Bonten, Marc, and Kluytmans, Jan

Published
2020
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30. A new surgical technique: robotic intracorporeal Kono‐S anastomosis in Crohn's – a safety and feasibility case series on short‐term outcomes.

Author

Smalbroek, Bo P., Poelmann, Floris B., and Smits, Anke B.

Subjects
OPERATIVE surgery, CROHN'S disease, SURGICAL anastomosis, PERIOPERATIVE care, SURGICAL complications
Abstract

Aim: The Kono‐S anastomosis was introduced as a possible solution to the high surgical recurrence rates in Crohn's disease. However, this technique is known to be challenging, which is why it was originally performed in an extracorporeal setting. The aim of this case series was to assess safety, in terms of intra‐/postoperative complications, and feasibility, in terms of successful performance of anastomosis, of a robot‐assisted intracorporeal Kono‐S anastomosis. Method: This is a prospective single‐centre consecutive case series. Patients were considered eligible if they were diagnosed with refractory Crohn's disease with significant bowel stenosis of the terminal ileum. All patients underwent robot‐assisted intracorporeal Kono‐S anastomosis. Perioperative care was provided according to the Enhanced Recovery After Surgery® protocol. Follow‐up for postoperative complications was 30 days. Results: Twenty patients were included, of whom 11 (55%) were men. The median age was 30 years [interquartile range (IQR) 22–51 years] and the median BMI was 25 kg/m2 (IQR 19–28 kg/m2). Intracorporeal Kono‐S anastomosis was successfully performed in all cases. The median operating time was 155 min (IQR 144–176 min) and the median length of stay was 3 days (IQR 1–5 days). No conversions or 30‐day mortality were observed. One patient experienced anastomotic leakage, which was treated with radiologically guided drainage. A total of three patients experienced postoperative complications in the first 30 days. Conclusion: Performance of intracorporeal robot‐assisted Kono‐S anastomosis seems safe and feasible in this case series for Crohn's disease. Since this is a first case series, further research is required to confirm results in a larger population‐based cohort. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Feasibility of Introducing a Prehabilitation Program into the Care of Gynecological Oncology Patients—A Single Institution Experience.

Author

Dhanis, Joëlle, Strijker, Dieuwke, Drager, Luuk D., van Ham, Maaike, van Laarhoven, Cornelis J. H. M., Pijnenborg, Johanna M. A., Smits, Anke, and van den Heuvel, Baukje

Subjects
SMOKING cessation, PATIENT safety, HUMAN services programs, EXERCISE, PREHABILITATION, SEDENTARY lifestyles, OVARIAN tumors, VULVAR tumors, ENDOMETRIAL tumors, CONVALESCENCE, CANCER patient psychology, DIETARY supplements
Abstract

Simple Summary: Surgery is the cornerstone in the treatment of most gynecological cancers and is associated with significant risks. Gynecological cancer patients are generally elderly, overweight, and have a sedentary lifestyle, which are all factors associated with surgical complications. Prehabilitation entails the optimizing of a patient's condition prior to surgery, and has been introduced with the goal of improving postoperative outcomes and recovery. A prehabilitation program has been implemented at an academic hospital in The Netherlands and comprises a physical exercise intervention, nutritional intervention, psychological intervention, and an intoxication cessation program. In this study, we assessed the feasibility of this program in terms of recruitment, adherence, and safety of implementation into the standard care of gynecological oncology patients. The principal finding was that the implementation of a prehabilitation program for gynecological oncology patients is feasible, with high recruitment and adherence rates. In addition, we did not encounter any major adverse events, suggesting its safety. Prehabilitation is an upcoming strategy to optimize patient's functional capacity, nutritional status, and psychosocial well-being in order to reduce surgical complications and enhance recovery. This study aims to assess the feasibility of implementing a multimodal prehabilitation program into the standard care of gynecological oncology patients at an academic hospital in terms of recruitment, adherence, and safety, which were assessed by the number of patients eligible, recruitment rate, participation rate, and adherence to individual modalities. Data were derived from the F4S PREHAB trial, a single-center stepped-wedge trial implementing a multimodal prehabilitation program among various surgical specialties. All patients undergoing elective surgery as part of treatment for ovarian, uterine, and vulvar cancer at the Radboudumc, an academic hospital in The Netherlands, between May 2022 and September 2023 were considered eligible for the F4S PREHAB trial and, consequently, were included in this cohort study. The multimodal prehabilitation program comprised a physical exercise intervention, nutritional intervention, psychological intervention, and an intoxication cessation program. A total of 152 patients were eligible and approached for participation of which 111 consented to participate, resulting in a recruitment rate of 73%. Participants attended an average of six exercise sessions and adhered to 85% of possible training sessions. Respectively, 93% and 98% of participants adhered to the prescribed daily protein and vitamin suppletion. Ten participants were referred to a psychologist and completed consultations. Out of nine active smokers, two managed to quit smoking. A total of 59% adhered to alcohol cessation advice. No adverse events were reported. This study demonstrates that introducing a multimodal prehabilitation program into the standard care of gynecological oncology patients is feasible in terms of recruitment and adherence, with no serious adverse events. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Nationwide standardization of minimally invasive right hemicolectomy for colon cancer and development and validation of a video-based competency assessment tool (the Right study).

Author

Grüter, Alexander A J, Toorenvliet, Boudewijn R, Belgers, Eric H J, Belt, Eric J T, van Duijvendijk, Peter, Hoff, Christiaan, Hompes, Roel, Smits, Anke B, van de Ven, Anthony W H, van Westreenen, Henderik L, Bonjer, Hendrik J, Tanis, Pieter J, Tuynman, Jurriaan B, the Right collaborators group, van Aalten, Sanne, Aarts, Frits, Abis, Gabor S A, Andeweg, Caroline S, Baan, Astrid H, and Baeten, Coen I M

Subjects
RIGHT hemicolectomy, COLON cancer, CARCINOGENESIS, INTRACLASS correlation, DELPHI method
Abstract

Background: Substantial variation exists when performing a minimally invasive right hemicolectomy (MIRH) due to disparities in training, expertise and differences in implementation of innovations. This study aimed to achieve national consensus on an optimal and standardized MIRH technique for colon cancer and to develop and validate a video-based competency assessment tool (CAT) for MIRH. Method: Statements covering all elements of MIRH were formulated. Subsequently, the Delphi technique was used to reach consensus on a standardized MIRH among 76 colorectal surgeons from 43 different centres. A CAT was developed based on the Delphi results. Nine surgeons assessed the same 12 unedited full-length videos using the CAT, allowing evaluation of the intraclass correlation coefficient (ICC). Results: After three Delphi rounds, consensus (≥80% agreement) was achieved on 23 of the 24 statements. Consensus statements included the use of low intra-abdominal pressure, detailed anatomical outline how to perform complete mesocolic excision with central vascular ligation, the creation of an intracorporeal anastomosis, and specimen extraction through a Pfannenstiel incision using a wound protector. The CAT included seven consecutive steps to measure competency of the MIRH and showed high consistency among surgeons with an overall ICC of 0.923. Conclusion: Nationwide consensus on a standardized and optimized technique of MIRH was reached. The CAT developed showed excellent interrater reliability. These achievements are crucial steps to an ongoing nationwide quality improvement project (the Right study). The Delphi technique was employed to achieve a broad national consensus on 23 statements among 76 colorectal surgeons, defining a standardized MIRH. This standard includes complete mesocolic excision, intracorporeal anastomosis and Pfannenstiel incision using a wound protector. Building upon this consensus, a video-based competency assessment tool was developed, exhibiting excellent reliability. [ABSTRACT FROM AUTHOR]

Published
2024
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34. The efficacy of a blended intervention to improve physical activity and protein intake for optimal physical recovery after oncological gastrointestinal and lung cancer surgery, the Optimal Physical Recovery After Hospitalization (OPRAH) trial: study protocol for a randomized controlled multicenter trial

Author

de Leeuwerk, Marijke, de Groot, Vincent, Dam, Suzanne ten, Kruizenga, Hinke, Weijs, Peter, Geleijn, Edwin, van der Leeden, Marike, van der Schaaf, Marike, Dickhoff, Chris, Besselink, Marc G., Tuynman, Jurriaan B., van Berge Henegouwen, Mark I., Erdmann, Joris I., Huijsmans, Rosalie J., van der Ploeg, Hidde P., Eskes, Anne M., Pijnappels, Mirjam A. G. M., van Leeuwen, Liesbeth Schuijs, Smits, Anke B., and van Dijk, Jasmijn

Subjects
LUNG surgery, GASTROINTESTINAL cancer, ONCOLOGIC surgery, RANDOMIZED controlled trials, LUNG cancer, PHYSICAL activity, COACHING psychology, MUSCLE mass
Abstract

Background: Improving physical activity, especially in combination with optimizing protein intake, after surgery has a potential positive effect on recovery of physical functioning in patients after gastrointestinal and lung cancer surgery. The aim of this randomized controlled trial is to evaluate the efficacy of a blended intervention to improve physical activity and protein intake after hospital discharge on recovery of physical functioning in these patients. Methods: In this multicenter single-blinded randomized controlled trial, 161 adult patients scheduled for elective gastrointestinal or lung cancer surgery will be randomly assigned to the intervention or control group. The purpose of the Optimal Physical Recovery After Hospitalization (OPRAH) intervention is to encourage self-management of patients in their functional recovery, by using a smartphone application and corresponding accelerometer in combination with coaching by a physiotherapist and dietician during three months after hospital discharge. Study outcomes will be measured prior to surgery (baseline) and one, four, eight, and twelve weeks and six months after hospital discharge. The primary outcome is recovery in physical functioning six months after surgery, and the most important secondary outcome is physical activity. Other outcomes include lean body mass, muscle mass, protein intake, symptoms, physical performance, self-reported limitations in activities and participation, self-efficacy, hospital readmissions and adverse events. Discussion: The results of this study will demonstrate whether a blended intervention to support patients increasing their level of physical activity and protein intake after hospital discharge improves recovery in physical functioning in patients after gastrointestinal and lung cancer surgery. Trial registration: The trial has been registered at the International Clinical Trials Registry Platform at 14–10-2021 with registration number NL9793. Trial registration data are presented in Table 1. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Is Cardiopulmonary Exercise Testing Predictive of Surgical Complications in Patients Undergoing Surgery for Ovarian Cancer?

Author

Smits, Anke, Agius, Claire-Marie, Blake, Dominic, Ang, Christine, Kucukmetin, Ali, Ham, Maaike van, Pijnenborg, Johanna M. A., Knight, Joanne, and Rundle, Stuart

Subjects
*EXERCISE tests, *LENGTH of stay in hospitals, *PREOPERATIVE care, *PREDICTIVE tests, *OVARIAN tumors, *CARDIOPULMONARY system, *CARDIOPULMONARY fitness, *OXYGEN consumption, *SURGICAL complications, *SURGERY, *PATIENTS, *RETROSPECTIVE studies, *PATIENT readmissions, *RISK assessment, *TREATMENT effectiveness, *TUMOR markers, *SENSITIVITY & specificity (Statistics), *LONGITUDINAL method, *DISEASE risk factors, *EVALUATION
Abstract

Simple Summary: Treatment of ovarian cancer often involves extensive surgery and is associated with an increased risk of surgical complications. Cardiopulmonary exercise testing (CPET) is a tool used to assess patients' cardiac and respiratory fitness, and the patient's ability to withstand the rigor of extensive surgery. Cardiorespiratory fitness is recognised as a predictive tool for surgical complications in many surgical specialities but has not yet been assessed in ovarian cancer patients. The aim of our retrospective study was to evaluate the value of CPET in predicting surgical complications in ovarian cancer surgery. In addition, we assessed the relationship between cardiorespiratory fitness and other outcomes such as hospital stay, readmission and resectability of disease. We found that patients with a raised VE/VCO2 observed during CPET, experienced more surgical complications. However, we did not find a relationship with other outcomes. Future studies are needed to further delineate the predictive value of CPET in this population. Preoperative cardiopulmonary exercise testing (CPET) provides an objective assessment of functional capability. In other intra-abdominal surgical specialties, CPET outcomes are predictive of operative morbidity. However, in ovarian cancer surgery, its predictive value remains unknown. In this study, we evaluated the association between CPET performance and surgical morbidity in ovarian cancer patients. Secondly, we assessed the association between CPET performance and other surgical outcomes (i.e., hospital stay, readmission and residual disease). This was a retrospective cohort study of patients undergoing primary surgery for ovarian cancer between 2020 and 2023. CPET performance included peak oxygen uptake (VO2 max), ventilatory efficiency (VE/VO2) and anaerobic threshold. Outcomes were operative morbidity and included intra- and postoperative complications (Clavien–Dindo), hospital stay, readmission within 30 days and residual disease. A total of 142 patients were included. A lower VO2 peak and a higher VE/VCO2 were both associated with the occurrence of postoperative complications, and a poorer anaerobic threshold was associated with more transfusions. VE/VCO2 remained significantly associated after multivariate analysis (p = 0.035). None of the CPET outcomes were associated with length of stay, readmission or residual disease. In conclusion, VE/VCO2 was significantly associated with an increased risk of all-cause postoperative complications in ovarian cancer patients undergoing primary surgery. [ABSTRACT FROM AUTHOR]

Published
2023
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36. National implementation of an optimal standardised technique for right-sided colon cancer: protocol of an interventional sequential cohort study (Right study).

Author

Grüter, Alexander A. J., Coblijn, Usha K., Toorenvliet, Boudewijn R., Tanis, Pieter J., Tuynman, Jurriaan B., the Right Collaborators Group, Aselmann, Heiko, Belgers, Eric H.J., Belt, Eric J.T., Benz, Stefan, Croner, Roland S, van Duijvendijk, Peter, Fletcher, Jordan, Hoff, Christiaan, Hompes, Roel, Miskovic, Danilo, Smits, Anke B., Stearns, Adam T., Storli, Kristian E., and van de Ven, Anthony W.H.

Subjects
COLON cancer, SURGICAL complications, COHORT analysis, RIGHT hemicolectomy, OPERATIVE surgery, DELPHI method, SURGICAL excision
Abstract

Purpose: Minimally invasive right hemicolectomy (MIRH) is the cornerstone of treatment for patients with right-sided colon cancer. This operation has evolved during recent decades, with many innovations and improvements but this has also resulted in high variability of uptake with subsequent substantial variableness. The aim of this ongoing study is to identify current surgical variations, determine the most optimal and standardised MIRH and nationally train and implement that technique to improve short-term clinical and long-term oncological outcomes. Methods: The Right study is a national multicentre prospective interventional sequential cohort study. Firstly, current local practice was evaluated. Subsequently, a standardised surgical technique for right-sided colon cancer was determined using the Delphi consensus method, and this procedure was trained during hands-on courses. The standardised MIRH will be implemented with proctoring (implementation cohort), after which the performance will be monitored (consolidation cohort). Patients who will receive a minimally invasive (extended) right hemicolectomy for cT1-3N0-2M0 colon cancer will be included. The primary outcome is patient safety reflected in the 90-day overall complication rate according to the Clavien–Dindo classification. Secondary outcomes will include intraoperative complications, 90-day mortality rate, number of resected tumour-positive lymph nodes, completeness of mesocolic excision, surgical quality score, locoregional and distant recurrence and 5-year overall survival. A total number of 1095 patients (365 per cohort) will be included. Discussion: The Right study is designed to safely implement the best surgical practice concerning patients with right-sided colon cancer aiming to standardise and improve the surgical quality of MIRH at a national level. Trial registration: ClinicalTrials.gov: NCT04889456, May 2021. [ABSTRACT FROM AUTHOR]

Published
2023
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44. A personalized app to improve quality of life of patients with a stoma: A protocol for a multicentre randomized controlled trial.

Author

van der Storm, Sebastiaan L., Bemelman, Willem A., van Dieren, Susan, Schijven, Marlies P., Consten, Esther C. J., Govaert, Marc J. P. M., Tuynman, Jurriaan B., Oosterling, Steven J., Grotenhuis, Brechtje A., Smits, Anke B., Marsman, Hendrik A., Buskens, Christianne J., Hompes, Roel, Kusters, Miranda, van Rossem, Charles C., van Duyn, Eino B., De Nes, Lindsey C. F., Verdaasdonk, Emiel, de Vries Reilingh, Tammo S., and Vening, Wouter

Subjects
OSTOMATES, PATIENT reported outcome measures, RANDOMIZED controlled trials, COLOSTOMY, QUALITY of life, ILEOSTOMY, LENGTH of stay in hospitals
Abstract

Aim: Proper education, guidance and support is crucial before and following creation of a stoma. Patients with a stoma and their close relatives need to adapt to and cope with this new – and sometimes unforeseen – situation, which may result in insecurities and a variety of psychosocial problems. Self‐efficacy is associated both with a reduction in psychosocial problems and with improved quality of life. The main objective of this study was to investigate whether self‐reported quality of life of patients with a stoma can be enhanced by offering personalized and timed guidance, as well as peer contact, in a patient‐centred mobile application. Method: A multicentre, double‐blind, randomized controlled trial will be conducted. Consented adults >18 years of age who will receive an ileostomy or colostomy and possess an eligible smartphone will be included. The intervention group will be given the full version of the application (containing personalized and timed guidance, such as operation‐specific information and information on the associated care pathway) to install on their smartphone. In addition, the intervention group has access to a protected peer‐support platform within the app. The control group will receive a restricted version of the application that contains only generic (non‐personalized) stoma‐related information. The primary outcome is quality of life, 3 months postoperatively. Secondary outcomes are Patient Reported Outcome Measures (PROMs), such as psychological adaption, as well as number of complications, re‐admission and re‐operation rates and the length of hospital stay. Results: Patient enrolment began in March 2021. Data collection was not complete when this protocol was submitted. Conclusion: We hypothesize that patients with a stoma who are supported by the intervention version of the app will report a significantly higher quality of life than patients with a stoma who are supported by the control version of the app (ie, are not offered personalized and timed guidance and information and do not have access to peer support in the app). [ABSTRACT FROM AUTHOR]

Published
2023
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45. Use of ileostomy versus colostomy as a bridge to surgery in left-sided obstructive colon cancer: retrospective cohort study.

Author

Smalbroek, Bo P, Weijs, Teus J, Dijksman, Lea M, Poelmann, Floris B, Goense, Lucas, Dijkstra, Robert R, Wijffels, Niels A T, Boerma, Djamila, Smits, Anke B, and Group, the Dutch Snapshot Research

Subjects
COLON cancer, COLOSTOMY, ILEOSTOMY, SURGICAL excision, SURGICAL complications, COHORT analysis, SURGERY
Abstract

Background Colorectal cancer causes the majority of large bowel obstructions and surgical resection remains the gold standard for curative treatment. There is evidence that a deviating stoma as a bridge to surgery can reduce postoperative mortality rate; however, the optimal stoma type is unclear. The aim of this study was to compare outcomes between ileostomy and colostomy as a bridge to surgery in left-sided obstructive colon cancer. Methods This was a national, retrospective population-based cohort study with 75 contributing hospitals. Patients with radiological left-sided obstructive colon cancer between 2009 and 2016, where a deviating stoma was used as a bridge to surgery, were included. Exclusion criteria were palliative treatment intent, perforation at presentation, emergency resection, and multivisceral resection. Results A total of 321 patients underwent a deviating stoma; 41 (12.7 per cent) ileostomies and 280 (87.2 per cent) colostomies. The ileostomy group had longer length of stay (median 13 (interquartile range (i.q.r.) 10–16) versus 9 (i.q.r. 6–14) days, P = 0.003) and more nutritional support during the bridging interval. Both groups showed similar complication rates in the bridging interval and after primary resection, including anastomotic leakage. Stoma reversal during resection was more common in the colostomy group (9 (22.0 per cent) versus 129 (46.1 per cent) for ileostomy and colostomy respectively, P = 0.006). Conclusion This study demonstrated that patients having a colostomy as a bridge to surgery in left-sided obstructive colon cancer had a shorter length of stay and lower need for nutritional support. No difference in postoperative complications were found. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Detection of colon cancer recurrences during follow-up care by general practitioners vs surgeons.

Author

Vos, Julien A M, Sert, Edanur, Busschers, Wim B, Duineveld, Laura A M, Wieldraaijer, Thijs, Wind, Jan, Donkervoort, Sandra C, Govaert, Marc J P M, Beverdam, Frédérique H, Smits, Anke B, Bemelman, Willem A, Heuff, Gijsbert, Weert, Henk C P M van, Asselt, Kristel M van, and Group, I CARE study

Subjects
COLON cancer, CANCER relapse, SURVIVAL rate, SURGEONS, EARLY detection of cancer, GENERAL practitioners
Abstract

Background In the I CARE study, colon cancer patients were randomly assigned to receive follow-up care from either a general practitioner (GP) or a surgeon. Here, we address a secondary outcome, namely, detection of recurrences and effect on time to detection of transferring care from surgeon to GP. Methods Pattern, stage, and treatment of recurrences were described after 3 years. Time to event was defined as date of surgery, until date of recurrence or last follow-up, with death as competing event. Effects on time to recurrence and death were estimated as hazard ratios (HRs) using Cox regression. Restricted mean survival times were estimated. Results Of 303 patients, 141 were randomly assigned to the GP and 162 to the surgeon. Patients were male (67%) with a mean age of 68.0 (8.4) years. During follow-up, 46 recurrences were detected; 18 (13%) in the GP vs 28 (17%) in the surgeon group. Most recurrences were detected via abnormal follow-up tests (74%) and treated with curative intent (59%). Hazard ratio for recurrence was 0.75 (95% confidence interval [CI] = 0.41 to 1.36) in GP vs surgeon group. Patients in the GP group remained in the disease-free state slightly longer (2.76 vs 2.71 years). Of the patients, 38 died during follow-up; 15 (11%) in the GP vs 23 (14%) in the surgeon group. Of these, 21 (55%) deaths were related to colon cancer. There were no differences in overall deaths between the groups (HR = 0.76, 95% CI = 0.39 to 1.46). Conclusion Follow-up provided by GPs vs surgeons leads to similar detection of recurrences. Also, no differences in mortality were found. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Comparison of three-year oncological results after restorative low anterior resection, non-restorative low anterior resection and abdominoperineal resection for rectal cancer.

Author

Hol, Jeroen C., Burghgraef, Thijs A., Rutgers, Marieke L.W., Crolla, Rogier M.P.H., van Geloven, Nanette A.W., Leijtens, Jeroen W.A., Polat, Fatih, Pronk, Apollo, Smits, Anke B., Tuynman, Jurriaan B., Verdaasdonk, Emiel G.G., Consten, Esther C.J., Hompes, Roel, and Sietses, Colin

Subjects
ABDOMINOPERINEAL resection, RECTAL cancer, ONCOLOGIC surgery, PROGRESSION-free survival, REGRESSION analysis, OVERALL survival
Abstract

Oncological outcome might be influenced by the type of resection in total mesorectal excision (TME) for rectal cancer. The aim was to see if non-restorative LAR would have worse oncological outcome. A comparison was made between non-restorative low anterior resection (NRLAR), restorative low anterior resection (RLAR) and abdominoperineal resection (APR). This retrospective cohort included data from patients undergoing TME for rectal cancer between 2015 and 2017 in eleven Dutch hospitals. A comparison was made for each different type of procedure (APR, NRLAR or RLAR). Primary outcome was 3-year overall survival (OS). Secondary outcomes included 3-year disease-free survival (DFS) and 3-year local recurrence (LR) rate. Of 998 patients 363 underwent APR, 132 NRLAR and 503 RLAR. Three-year OS was worse after NRLAR (78.2%) compared to APR (86.3%) and RLAR (92.2%, p < 0.001). This was confirmed in a multivariable Cox regression analysis (HR 1.85 (1.07, 3.19), p = 0.03). The 3-year DFS was also worse after NRLAR (60.3%), compared to APR (70.5%) and RLAR (80.1%, p < 0.001), HR 2.05 (1.42, 2.97), p < 0.001. The LR rate was 14.6% after NRLAR, 5.2% after APR and 4.8% after RLAR (p = 0.005), HR 3.22 (1.61, 6.47), p < 0.001. NRLAR might be associated with worse 3-year OS, DFS and LR rate compared to RLAR and APR. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Reliability, Validity, and Responsiveness of the Western Ontario and McMaster Universities Osteoarthritis Index for Elderly Patients with a Femoral Neck Fracture

Author

Burgers, Paul T.P.W., Poolman, Rudolf W, Van Bakel, Theodorus MJ, Tuinebreijer, Wim E, Zielinski, Stephanie M, Bhandari, Mohit, Patka, Peter, Van Lieshout, Esther MM, Bhandari, Mohit, Devereaux, P J, Guyatt, Gordon H, Einhorn, Thomas A, Thabane, Lehana, Schemitsch, Emil H, Koval, Kenneth J, Frihagen, Frede, Poolman, Rudolf W, Tetsworth, Kevin, Guerra-Farfan, Ernesto, Walter, Stephen D, Sprague, Sheila, Swinton, Marilyn, Scott, Taryn, McKay, Paula, Madden, Kim, Heels-Ansdell, Diane, Buckingham, Lisa, Duraikannan, Aravin, Silva, Heather, Heetveld, Martin J, Van Lieshout, Esther MM, Burgers, Paul T.P.W., Zura, Robert D, Avram, Victoria, Manjoo, Ajay, Williams, Dale, Antoniou, John, Ramsay, Tim, Bogoch, Earl R, Trenholm, Andrew, Lyman, Stephen, Mazumdar, Madhu, Bozic, Kevin J, Luborsky, Mark, Goodman, Stuart, Muray, Susan, Korley, Rob, Buckley, Richard, Duffy, Paul, Puloski, Shannon, Carcary, Kimberly, Lorenzo, Melissa, McKee, Michael D, Hall, Jeremy A, Nauth, Aaron, Whelan, Daniel, Daniels, Timothy R, Waddell, James P, Ahn, Henry, Vicente, Milena R, Hidy, Jennifer T, MacNevin, Melanie T, Kreder, Hans, Axelrod, Terry, Jenkinson, Richard, Nousiainen, Markku, Stephen, David, Wadey, Veronica, Kunz, Monica, Milner, Katrine, Cagaanan, Ria, MacNevin, Melanie, O’Brien, Peter J, Blachut, Piotr A, Broekhuyse, Henry M, Guy, Pierre, Lefaivre, Kelly A, Slobogean, Gerard P, Johal, Raman, Leung, Irene, Coles, Chad, Leighton, Ross, Richardson, C. Glen, Biddulph, Michael, Gross, Michael, Dunbar, Michael, Amirault, J. David, Alexander, David, Coady, Catherine, Glazebrook, Mark, Johnston, David, Oxner, William, Reardon, Gerald, Wong, Ivan, Trask, Kelly, MacDonald, Shelley, Furey, Andrew, Stone, Craig, Parsons, Minnie, Stone, Trevor, Zomar, Mauri, McCormack, Robert, Apostle, Kelly, Boyer, Dory, Moola, Farhad, Perey, Bertrand, Viskontas, Darius, Moon, Karyn, Moon, Raely, Laflamme, Yves, Benoit, Benoit, Ranger, Pierre, Malo, Michel, Fernandes, Julio, Tardif, Karine, Fournier, Julie, Vendittoli, Pascal André, Massé, Vincent, Roy, Alain G, Lavigne, Martin, Lusignan, Daniel, Davis, Craig, Stull, Philip, Weinerman, Stewart, Weingarten, Peter, Lindenbaum, Steven, Hewitt, Michael, Danielwicz, Rebecca, Baker, Janell, Mont, Michael, Delanois, Donald E, Kapadia, Bhaveen, Issa, Kimona, Mullen, Marylou, Sems, Andrew, Foreman, Barb, Parvizi, Javad, Morrison, Tiffany, Lewis, Courtland, Caminiti, Stephanie, Tornetta, Paul, III, Creevy, William R, Lespasio, Michelle J, Carlisle, Hope, Marcantonio, Andrew, Kain, Michael, Specht, Lawrence, Tilzey, John, Garfi, John, Mehta, Samir, Esterhai, John L, Jr., Ahn, Jaimo, Donegan, Derek, Horan, Annamarie, McGinnis, Kelly, Roberson, James, Bradbury, Thomas, Erens, Greg, Webb, Kyle, Mullis, Brian, Shively, Karl, Parr, Andrew, Ertl, Janos, Worman, Ripley, Webster, Mark, Cummings, Judd, Frizzell, Valda, Moore, Molly, Jones, Clifford B, Ringler, James R, Sietsema, Debra L, Walker, Jane E, Kanlic, Enes, Abdelgawad, Amr, Shunia, Juan, DePaolo, Charles, Sutherland, Susan, Alosky, Rachel, Zura, Robert, Manson, Maria, Strathy, Gregg, Peter, Kathleen, Johnson, Paul, Morton, Meaghan, Shaer, James, Schrickel, Tyson, Hileman, Barbara, Hanes, Marina, Chance, Elisha, Heinrich, E. Matthew, Dodgin, David, LaBadie, Michele, Zamorano, David, Tynan, Martin, Schwarzkopf, Ran, Scolaro, John A, Gupta, Ranjan, Bederman, Samuel, Bhatia, Nitin, Hoang, Bang, Kiester, Douglas, Jones, Neil, Rafijah, Gregory, Alavekios, Damon, Lee, Jason, Mehta, Akshay, Schroder, Steven, Chao, Tom, Colin, Vincent, Dang, Phuc (Phil), Heng, Stephen Keun, Lopez, Gregory, Galle, Samuel, Pahlavan, Sohrab, Phan, Duy L, Tapadia, Minal, Bui, Christopher, Jain, Nickul, Moore, Tyler, Moroski, Nathan, Pourmand, Deeba, Kubiak, Erik N, Gililland, Jeremy, Rothberg, David, Peters, Christopher, Pelt, Christopher, Stuart, Ami R, Corbey, Kirby, Shuler, Franklin D, Day, James, Garabekyan, Tigran, Cheung, Felix, Oliashirazi, Ali, Salava, Jonathon, Morgan, Linda, Wilson-Byrne, Timothy, Cordle, Mary Beth, Elmans, Leon H.G.J., van den Hout, Joost A.A.M., Joosten, Adrianus JP, van Beurden, Ad FA, Bolder, Stefan BT, Eygendaal, Denise, Moonen, Adrianus F.C.M., van Geenen, Rutger CI, Hoebink, Eric A, Wagenmakers, Robert, van Helden, Wouter, van Jonbergen, Hans-Peter W, Roerdink, Herbert, Reuver, Joost M, Barnaart, Alexander FW, Flikweert, Elvira R, Krips, Rover, Mullers, J. Bernard, Schüller, Hans, Falke, Mark LM, Kurek, Frans J, Slingerland, Adrianus CH, van Dijk, Jan P, van Helden, Wouter H, Bolhuis, Hugo W, Bullens, Pieter HJ, Hogervorst, Mike, de Kroon, Karin E, Jansen, Rob H, Steenstra, Ferry, Raven, Eric EJ, Fontijne, W. Peter J, Wiersma, Saskia C, Boetes, Bastiaan, ten Holder, Edgar JT, van der Heide, Huub JL, Nagels, Jochem, van der Linden-van der Zwaag, Enrike H.M.J., Keizer, Stefan B, Swen, Jan-Willem A, den Hollander, Peter HC, Thomassen, Bregje JW, Molekamp, Willem Jan Kleyn, de Meulemeester, Frank R.A.J., Kleipool, Arthur EB, Haverlag, Robert, Simons, Maarten P, Mutsaerts, Eduard L.A.R., Kooijman, Rob, Postema, Roelf R, Bleker, René J.T.M., Lampe, Harald IH, Schuman, Lein, Cheung, John, van Bommel, Frank, Winia, W. Paul, Haverkamp, Daniel, van der Vis, Harm, Nolte, Peter A, van den Bekerom, Michel PJ, de Jong, Tjitte, van Noort, Arthur, Vergroesen, Diederik A, Schutte, Bernard G, van der Vis, Harm M, Beimers, Lijkele, de Vries, Jasper, Zurcher, Arthur W, Albers, G.H. Rob, Rademakers, Maarten, Breugem, Stefan, van der Haven, Ibo, Jan Damen, Pieter, Bulstra, Gythe H, Campo, Martin M, Somford, Mathijs P, Haverkamp, Daniël, Liew, Susan, Bedi, Harvinder, Carr, Ashley, Chia, Andrew, Csongvay, Steve, Donohue, Craig, Doig, Stephen, Edwards, Elton, Esser, Max, Freeman, Richard, Gong, Andrew, Li, Doug, Miller, Russell, Ton, Lu, Wang, Otis, Young, Ian, Dowrick, Adam, Murdoch, Zoe, Sage, Claire, Page, Richard, Bainbridge, David, Angliss, Richard, Miller, Ben, Thomson, Andrew, Brown, Graeme, Williams, Simon, Eng, Kevin, Bowyer, David, Skelley, John, Goyal, Chatar, Beattie, Sally, Guerado, Enrique, Cruz, Encarnacion, Cano, Juan Ramon, Froufe, Miguel Angel, Serra, Lluis Marull, Al-dirra, Samer, Martinez, Cristina, Tarazona Santabalbina, Francisco José, Serra, Jordi Teixidor, Hernandez, Jordi Tomas, Garcia, Marc Aguilar, Garcia, Vicente Molero, Barrera, Sergi, Garrido, Miriam, Nordsletten, Lars, Clarke-Jenssen, John, Hjorthaug, Geir, Brekke, Anne Christine, Vesterhus, Elise Berg, Skaugrud, Ingunn, Tripathi, Pradeep, Katiyar, Sandesh, Shukla, Preksha, Swiontkowski, Marc, Guyatt, Gordon, Jeray, Kyle, Walter, Stephen, Viveiros, Helena, Truong, Victoria, Koo, Kaitlin, Zhou, Qi, Maddock, Deborah, Simunovic, Nicole, Agel, Julie, Zielinski, Stephanie M, Rangan, Amar, Hanusch, Birgit C, Kottam, Lucksy, Clarkson, Rachel, Della Rocca, Gregory J, Slobogean, Gerard, Katz, Jeffrey, Gillespie, Brenda, Greendale, Gail A, Hartman, Curtis, Rubin, Craig, Waddell, James, Lemke, H. Michael, Oatt, Amber, Buckley, Richard E, Korley, Robert, Johnston, Kelly, Powell, James, Sanders, David, Lawendy, Abdel, Tieszer, Christina, Murnaghan, John, Nam, Diane, Yee, Albert, Whelan, Daniel B, Wild, Lisa M, Khan, Ryan M, Coady, Cathy, Amirault, David, Richardson, Glen, Dobbin, Gwen, Bicknell, Ryan, Yach, Jeff, Bardana, Davide, Wood, Gavin, Harrison, Mark, Yen, David, Lambert, Sue, Howells, Fiona, Ward, Angela, Zalzal, Paul, Brien, Heather, Naumetz, V, Weening, Brad, Wai, Eugene K, Papp, Steve, Gofton, Wade T, Kingwell, Stephen P, Johnson, Garth, O’Neil, Joseph, Roffey, Darren M, Borsella, Vivian, Oliver, Todd M, Jones, Vicki, Endres, Terrence J, Agnew, Samuel G, Jeray, Kyle J, Broderick, J. Scott, Goetz, David R, Pace, Thomas B, Schaller, Thomas M, Porter, Scott E, Tanner, Stephanie L, Snider, Rebecca G, Nastoff, Lauren A, Bielby, Shea A, Switzer, Julie A, Cole, Peter A, Anderson, Sarah A, Lafferty, Paul M, Li, Mengnai, Ly, Thuan V, Marston, Scott B, Foley, Amy L, Vang, Sandy, Wright, David M, Marcantonio, Andrew J, Kain, Michael SH, Iorio, Richard, Specht, Lawrence M, Tilzey, John F, Lobo, Margaret J, Garfi, John S, Vallier, Heather A, Dolenc, Andrea, Robinson, Chalitha, Prayson, Michael J, Laughlin, Richard, Rubino, L. Joseph, May, Jedediah, Rieser, Geoffrey Ryan, Dulaney-Cripe, Liz, Gayton, Chris, Gorczyca, John T, Gross, Jonathan M, Humphrey, Catherine A, Kates, Stephen, Noble, Krista, McIntyre, Allison W, Pecorella, Kaili, Davis, Craig A, Lindenbaum, Stephen, Schwappach, John, Baker, Janell K, Rutherford, Tori, Newman, Heike, Lieberman, Shane, Finn, Erin, Robbins, Kristin, Hurley, Meghan, Lyle, Lindsey, Mitchell, Khalis, Browner, Kieran, Whatley, Erica, Payton, Krystal, Reeves, Christina, Cannada, Lisa K, Karges, David, Hill, Leslie, Esterhai, John, Horan, Annamarie D, Kaminski, Christine A, Kowalski, Brynn N, Keeve, Jonathan P, Anderson, Christopher G, McDonald, Michael D, Hoffman, Jodi M, Tarkin, Ivan, Siska, Peter, Gruen, Gary, Evans, Andrew, Farrell, Dana J, Irrgang, James, Luther, Arlene, Cross, William W, III, Cass, Joseph R, Sems, Stephen A, Torchia, Michael E, Scrabeck, Tyson, Jenkins, Mark, Dumais, Jules, Romero, Amanda W, Sagebien, Carlos A, Butler, Mark S, Monica, James T, Seuffert, Patricia, Hsu, Joseph R, Ficke, James, Charlton, Michael, Napierala, Matthew, Fan, Mary, Tannoury, Chadi, Archdeacon, Michael, Finnan, Ryan, Le, Toan, Wyrick, John, Hess, Shelley, Brennan, Michael L, Probe, Robert, Kile, Evelyn, Mills, Kelli, Clipper, Lydia, Yu, Michelle, Erwin, Katie, Horwitz, Daniel, Strohecker, Kent, Swenson, Teresa K, Schmidt, Andrew H, Westberg, Jerald R, Aurang, Kamran, Zohman, Gary, Peterson, Brett, Huff, Roger B, Baele, Joseph, Weber, Timothy, Edison, Matt, McBeth, Jessica, Ertl, Janos P, Parr, J. Andrew, Moore, Molly M, Tobias, Erin, Thomas, Emily, DePaolo, Charles J, Shell, Leslie E, Hampton, Lynne, Shepard, Stephanie, Nanney, Tracy, Cuento, Claudine, Cantu, Robert V, Henderson, Eric R, Eickhoff, Linda S, Hammerberg, E. Mark, Stahel, Philip, Hak, David, Mauffrey, Cyril, Gibula, Douglas, Gissel, Hannah, Henderson, Corey, Zamorano, David P, Tynan, Martin C, Lawson, Deanna, Crist, Brett D, Murtha, Yvonne M, Anderson, Linda K, Linehan, Colleen, Pilling, Lindsey, Lewis, Courtland G, Sullivan, Raymond J, Roper, Elizabeth, Obremskey, William, Kregor, Philip, Richards, Justin E, Stringfellow, Kenya, Dohm, Michael P, Zellar, Abby, Segers, Michiel JM, Zijl, Jacco AC, Verhoeven, Bart, Smits, Anke B, de Vries, Jean Paul PM, Fioole, Bram, van der Hoeven, Henk, Theunissen, Evert BM, de Vries Reilingh, Tammo S, Govaert, Lonneke, Wittich, Philippe, de Brauw, Maurits, Wille, Jan, Go, Peter M.N.Y.M., Ritchie, Ewan D, Wessel, Ronald N, Hammacher, Eric R, Visser, Gijs A, Stockmann, Heyn, Silvis, Rob, Snellen, Jaap P, Rijbroek, Bram, Scheepers, Joris JG, Vermeulen, Erik GJ, Siroen, Michiel PC, Vuylsteke, Ronald, Brom, Hans LF, Rijna, Herman, de Rijcke, Piet AR, Koppert, Cees L, Buijk, Steven E, Groenendijk, Richard PR, Dawson, Imro, Tetteroo, Geert WM, Bruijninckx, Milko MM, Doornebosch, Pascal G, de Graaf, Eelco JR, van der Elst, Maarten, van der Pol, Carmen C, van’t Riet, Martijne, Karsten, Tom M, de Vries, Mark R, Stassen, Laurents PS, Schep, Niels WL, Ben Schmidt, G, Hoffman, W H, van der Heijden, Frank H.W.M., Willems, W. Jaap, van der Hart, Cor P, Turckan, Kahn, Festen, Sebastiaan, de Nies, Frank, Out, Nico JM, Bosma, Jan, van Kampen, Albert, Biert, Jan, van Vugt, Arie B, Edwards, Michael JR, Blokhuis, Taco J, Frölke, Jan Paul M, Geeraedts, Leo MG, Gardeniers, Jean WM, Tan, Edward T.C.H., Poelhekke, Lodewijk M.S.J., de Waal Malefijt, Maarten C, Schreurs, Bart, Roukema, Gert R, Josaputra, Hong A, Keller, Paul, de Rooij, Peter D, Kuiken, Hans, Boxma, Han, Cleffken, Berry I, Liem, Ronald, Rhemrev, Steven J, Bosman, Coks HR, de Mol van Otterloo, Alexander, Hoogendoorn, Jochem, de Vries, Alexander C, Meylaerts, Sven AG, Verhofstad, Michiel HJ, Meijer, Joost, van Egmond, Teun, van der Brand, Igor, Patka, Peter, Eversdijk, Martin G, Peters, Rolf, Den Hartog, Dennis, Van Waes, Oscar JF, Oprel, Pim, Campo, Martin, Verhagen, Ronald, Albers, G.H. Robert, Simmermacher, Rogier KJ, van Mulken, Jeroen, van Wessem, Karlijn, van Gaalen, Steven M, Leenen, Luke PH, Bronkhorst, Maarten W.G.A., Guicherit, Onno R, Goslings, J. Carel, Ponsen, Kees Jan, Bhatia, Mahesh, Arora, Vinod, Tyagi, Vivek, Gupta, Ajay, Jain, Neeraj, Khan, Farah, Sharma, Ateet, Sanghavi, Amir, Trivedi, Mittal, Rai, Anil, Subash, Rai, Kamal, Yadav, Vineet, Singh, Sanjay, Prasad, Amal Shankar, Mishra, Vimlesh, Sundaresh, D C, Khanna, Angshuman, Cherian, Joe Joseph, Olakkengil, Davy J, Sharma, Gaurav, Dadi, Akhil, Palla, Naveen, Ganguly, Utsav, Rai, B. Sachidananda, Rajakumar, Janakiraman, Hull, Peter, Lewis, Sophie, Evans, Simone, Nanda, Rajesh, Logishetty, Rajanikanth, Anand, Sanjeev, Bowler, Carol, Jennings, Andrew, Chuter, Graham, Rose, Glynis, Horner, Gillian, Clark, Callum, Eke, Kate, Reed, Mike, Herriott, Chris, Dobb, Christine, Curry, Hamish, Etherington, Greg, Jain, Arvind, Moaveni, Ash, Russ, Matthias, Donald, Geoff, Weinrauch, Patrick, Pincus, Paul, Yang, Steven, Halliday, Brett, Gervais, Trevor, Holt, Michael, Flynn, Annette, Pirpiris, Marinis, Love, David, Bucknill, Andrew, Farrugia, Richard J, Ianssen, Torben, Amundsen, Asgeir, Brattgjerd, Jan Egil, Borch, Tor, Bøe, Berthe, Flatøy, Bernhard, Hasselund, Sondre, Haug, Knut Jørgen, Hemlock, Kim, Hoseth, Tor Magne, Jomaas, Geir, Kibsgård, Thomas, Lona, Tarjei, Moatshe, Gilbert, Müller, Oliver, Molund, Marius, Nicolaisen, Tor, Nilsen, Fredrik, Rydinge, Jonas, Smedsrud, Morten, Stødle, Are, Trommer, Axel, Ugland, Stein, Karlsten, Anders, Ekås, Guri, Pape, Hans-Christoph, Knobe, Matthias, and Pfeifer, Roman

Published
2015
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