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1,171 results on '"Skinner S"'

4. Impact of COVID-19 & Response Measures on HIV-HCV Prevention Services and Social Determinants in People Who Inject Drugs in 13 Sites with Recent HIV Outbreaks in Europe, North America and Israel

Author

Wiessing, Lucas, Sypsa, V., Abagiu, A. O., Arble, A., Berndt, N., Bosch, A., Buskin, S., Chemtob, D., Combs, B., Conyngham, C., Feelemyer, J., Fitzgerald, M., Goldberg, D., Hatzakis, A., Patrascu, R. E., Keenan, E., Khan, I., Konrad, S., Leahy, J., McAuley, A., Menza, T., Merrick, S., Metcalfe, R., Rademaker, T., Revivo, S., Rosca, P., Seguin-Devaux, C., Skinner, S., Smith, C., Tinsley, J., Wilberg, M., and Des Jarlais, D.

Published
2023
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5. The study design and methodology for the ARCHER study - adolescent rural cohort study of hormones, health, education, environments and relationships

Author

Steinbeck Katharine, Hazell Philip, Cumming Robert G, Skinner S, Ivers Rebecca, Booy Robert, Fulcher Greg, Handelsman David J, Martin Andrew J, Morgan Geoff, Starling Jean, Bauman Adrian, Rawsthorne Margot L, Bennett David L, Chow Chin, Lam Mary K, Kelly Patrick, Brown Ngiare J, Paxton Karen, and Hawke Catherine

Subjects
Puberty, Hormones, Adolescent, Cohort studies, Rural health, Behaviour, Wellbeing, Public health, Protocol, Paediatrics, Pediatrics, RJ1-570
Abstract

Abstract Background Adolescence is characterized by marked psychosocial, behavioural and biological changes and represents a critical life transition through which adult health and well-being are established. Substantial research confirms the role of psycho-social and environmental influences on this transition, but objective research examining the role of puberty hormones, testosterone in males and oestradiol in females (as biomarkers of puberty) on adolescent events is lacking. Neither has the tempo of puberty, the time from onset to completion of puberty within an individual been studied, nor the interaction between age of onset and tempo. This study has been designed to provide evidence on the relationship between reproductive hormones and the tempo of their rise to adult levels, and adolescent behaviour, health and wellbeing. Methods/Design The ARCHER study is a multidisciplinary, prospective, longitudinal cohort study in 400 adolescents to be conducted in two centres in regional Australia in the State of New South Wales. The overall aim is to determine how changes over time in puberty hormones independently affect the study endpoints which describe universal and risk behaviours, mental health and physical status in adolescents. Recruitment will commence in school grades 5, 6 and 7 (10–12 years of age). Data collection includes participant and parent questionnaires, anthropometry, blood and urine collection and geocoding. Data analysis will include testing the reliability and validity of the chosen measures of puberty for subsequent statistical modeling to assess the impact over time of tempo and onset of puberty (and their interaction) and mean-level repeated measures analyses to explore for significant upward and downward shifts on target outcomes as a function of main effects. Discussion The strengths of this study include enrollment starting in the earliest stages of puberty, the use of frequent urine samples in addition to annual blood samples to measure puberty hormones, and the simultaneous use of parental questionnaires.

Published
2012
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8. Health, social and economic implications of adolescent risk behaviours/states: protocol for Raine Study Gen2 cohort data linkage study

Author

Marino, Jennifer L., Tait, Robert J., Straker, Leon M., Schofield, Deborah J., Doherty, Dorota A., Ivers, Rebecca Q., Graham, Petra L., Steinbeck, Katharine, Lymer, Sharyn, Sanci, Lena A., Patton, George C., Liu, Bette, Brooks, Fiona M., Kang, Melissa S., Hickey, Martha, Cunich, Michelle, Bista, Sarita, and Skinner, S. Rachel

Published
2022
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11. Measuring school level attributable risk to support school-based HPV vaccination programs

Author

Vujovich-Dunn, C., Wand, H., Brotherton, J. M. L., Gidding, H., Sisnowski, J., Lorch, R., Veitch, M., Sheppeard, V., Effler, P., Skinner, S. R., Venn, A., Davies, C., Hocking, J., Whop, L., Leask, J., Canfell, K., Sanci, L., Smith, M., Kang, M., Temple-Smith, M., Kidd, M., Burns, S., Selvey, L., Meijer, D., Ennis, S., Thomson, C., Lane, N., Kaldor, J., and Guy, R.

Published
2022
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13. Safeguarding the health and wellbeing of transgender young people.

Author

Pace, Carmen, Chinsen, Alessandra, Cheung, Ada S, Skinner, S. Rachel, Knight, Ken W, Tollit, Michelle A, Telfer, Michelle M, and Pang, Ken C

Abstract

The article discusses the challenges faced by transgender young people in safeguarding their health and well-being, particularly in the face of increasing anti-trans campaigns and discrimination. It highlights the adverse impact of such discourse on the mental health of young trans individuals and calls for urgent action to protect their rights and dignity. The text emphasizes the importance of providing gender-affirming care and support to trans youth, as research shows that access to such care is associated with improved mental health outcomes. The article concludes by urging healthcare providers, researchers, educators, politicians, and the media to promote inclusive practices, challenge anti-trans attitudes, and amplify the voices of trans individuals to combat transphobia and ensure the well-being of young trans people. [Extracted from the article]

Published
2024
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15. "I Thought It Was Better to Be Safe Than Sorry": Factors Influencing Parental Decisions on HPV and Other Adolescent Vaccinations for Students with Intellectual Disability and/or Autism in New South Wales, Australia.

Author

Carter, Allison, Klinner, Christiane, Young, Alexandra, Strnadová, Iva, Wong, Horas, Vujovich-Dunn, Cassandra, Newman, Christy E., Davies, Cristyn, Skinner, S. Rachel, Danchin, Margie, Hynes, Sarah, and Guy, Rebecca

Subjects
HEALTH attitudes, YOUNG adults, HUMAN papillomavirus, VACCINE hesitancy, PARENT attitudes
Abstract

The uptake of human papilloma virus (HPV) and other adolescent vaccinations in special schools for young people with disability is significantly lower than in mainstream settings. This study explored the factors believed to influence parental decision making regarding vaccine uptake for students with intellectual disability and/or on the autism spectrum attending special schools in New South Wales, Australia, from the perspective of all stakeholders involved in the program. Focus groups and interviews were conducted with 40 participants, including parents, school staff, and immunisation providers. The thematic analysis identified two themes: (1) appreciating diverse parental attitudes towards vaccination and (2) educating parents and managing vaccination questions and concerns. While most parents were described as pro-vaccination, others were anti-vaccination or vaccination-hesitant, articulating a marked protectiveness regarding their child's health. Reasons for vaccine hesitancy included beliefs that vaccines cause autism, concerns that the vaccination may be traumatic for the child, vaccination fatigue following COVID-19, and assumptions that children with disability will not be sexually active. Special school staff regarded the vaccination information pack as inadequate for families, and nurses described limited educational impact resulting from minimal direct communication with parents. More effective communication strategies are needed to address vaccine hesitancy among parents with children with disability. [ABSTRACT FROM AUTHOR]

Published
2024
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23. A trial protocol for the effectiveness of digital interventions for preventing depression in adolescents: The Future Proofing Study

Author

Werner-Seidler, Aliza, Huckvale, Kit, Larsen, Mark E., Calear, Alison L., Maston, Kate, Johnston, Lara, Torok, Michelle, O’Dea, Bridianne, Batterham, Philip J., Schweizer, Susanne, Skinner, S. Rachel, Steinbeck, Katharine, Ratcliffe, Julie, Oei, Ju-Lee, Patton, George, Wong, Iana, Beames, Joanne, Wong, Quincy J. J., Lingam, Raghu, Boydell, Katherine, Salmon, Allison M., Cockayne, Nicole, Mackinnon, Andrew, and Christensen, Helen

Published
2020
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24. Recognizing and responding to misleading trans health research.

Author

Skinner, S. Rachel, McLamore, Quinnehtukqut, Donaghy, Olivia, Stathis, Stephen, Moore, Julia K., Nguyen, Tram, Rayner, Cate, Tait, Robert, Anderson, Jemma, and Pang, Ken C.

Subjects
*HEALTH services accessibility, *SERIAL publications, *CULTURAL pluralism, *PSYCHOSOCIAL factors, *COMMUNICATION, *TRANSGENDER people, *PSYCHOLOGICAL distress, *MENTAL illness
Abstract

The article focuses on the evolving landscape of trans health research, addressing changes in public discourse, care options, and research standards. Topics include shifting perceptions of transgender identity, emerging ethical standards in research, and the politicization of gender-affirming interventions, with particular concern regarding potential regret and harm among trans young people.

Published
2024
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25. Development of a Human Papillomavirus Vaccination Intervention for Australian Adolescents

Author

Cooper, Spring C., Davies, Cristyn, McBride, Kate, Blades, Joanna, Stoney, Tanya, Marshall, Helen, and Skinner, S. Rachel

Abstract

Objective: Australia has implemented a nation-wide programme providing a human papillomavirus (HPV) vaccine to girls and boys through school-based programmes. Previous research has identified three distinct areas for attention: (1) lack of understanding about HPV and HPV vaccination, (2) young people's desire for involvement in decision-making about HPV vaccination and (3) fear of HPV vaccination. We aimed to develop an intervention to address young people's low levels of understanding, to promote their involvement in consent and reduce vaccination-related fear and anxiety. Design, Setting, Methods: Formative qualitative research was conducted in six public, private and Catholic schools in the Sydney metropolitan area. Girls who were offered the vaccine in a school programme and aged 12-13 years were interviewed in focus groups. Piloting of materials was conducted in three private schools across Sydney with both girls and boys, and changes and additions were made to the materials in accordance with feedback. Results: We developed an educational intervention aimed at addressing gaps in young people's knowledge and understanding, and offering strategies to improve confidence with vaccination and reduce needle-related anxiety. Components of the final intervention include film chapters, a magazine, a website, an app and teacher support materials. The intervention is designed for teachers and/or nurses to deliver and is linked to the school-based HPV vaccination programme. Conclusions: This is the first educational intervention designed for young people in HPV school-based vaccination, to be developed from empirical data with the involvement of young people themselves.

Published
2016
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26. Rapid transition from continental breakup to igneous oceanic crust in the South China Sea

Author

Larsen, H. C., Mohn, G., Nirrengarten, M., Sun, Z., Stock, J., Jian, Z., Klaus, A., Alvarez-Zarikian, C. A., Boaga, J., Bowden, S. A., Briais, A., Chen, Y., Cukur, D., Dadd, K., Ding, W., Dorais, M., Ferré, E. C., Ferreira, F., Furusawa, A., Gewecke, A., Hinojosa, J., Höfig, T. W., Hsiung, K. H., Huang, B., Huang, E., Huang, X. L., Jiang, S., Jin, H., Johnson, B. G., Kurzawski, R. M., Lei, C., Li, B., Li, L., Li, Y., Lin, J., Liu, C., Liu, C., Liu, Z., Luna, A. J., Lupi, C., McCarthy, A., Ningthoujam, L., Osono, N., Peate, D. W., Persaud, P., Qiu, N., Robinson, C., Satolli, S., Sauermilch, I., Schindlbeck, J. C., Skinner, S., Straub, S., Su, X., Su, C., Tian, L., van der Zwan, F. M., Wan, S., Wu, H., Xiang, R., Yadav, R., Yi, L., Yu, P. S., Zhang, C., Zhang, J., Zhang, Y., Zhao, N., Zhong, G., and Zhong, L.

Published
2018
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27. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 7-year follow-up of the phase 3, double-blind, randomised controlled VIVIANE study

Author

Wheeler, Cosette M, Skinner, S Rachel, Del Rosario-Raymundo, M Rowena, Garland, Suzanne M, Chatterjee, Archana, Lazcano-Ponce, Eduardo, Salmerón, Jorge, McNeil, Shelly, Stapleton, Jack T, Bouchard, Céline, Martens, Mark G, Money, Deborah M, Quek, Swee Chong, Romanowski, Barbara, Vallejos, Carlos S, ter Harmsel, Bram, Prilepskaya, Vera, Fong, Kah Leng, Kitchener, Henry, Minkina, Galina, Lim, Yong Kuei Timothy, Stoney, Tanya, Chakhtoura, Nahida, Cruickshank, Margaret E, Savicheva, Alevtina, da Silva, Daniel Pereira, Ferguson, Murdo, Molijn, Anco C, Quint, Wim G V, Hardt, Karin, Descamps, Dominique, Suryakiran, Pemmaraju V, Karkada, Naveen, Geeraerts, Brecht, Dubin, Gary, and Struyf, Frank

Published
2016
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29. Association of urinary sex hormones with mood and behavior changes in a community adolescent cohort.

Author

Hazell, Philip, Balzer, Ben W. R., Garden, Frances, Handelsman, David J., Paxton, Karen, Hawke, Catherine, Ivers, Rebecca, Skinner, S. Rachel, Luscombe, Georgina, and Steinbeck, Katharine S.

Subjects
SEX hormones, PUBERTY, LIQUID chromatography-mass spectrometry, TEENAGE girls, TEENAGERS, COMMUNITY change, URINE, FEMALES
Abstract

Objective: To examine the contribution of variation in sex hormone excretion to mood and behavioral changes in adolescent females and males. Design: Prospective, longitudinal observational cohort study. Methods: Participants were 342 volunteers aged 10–12 years living in rural Australia. Urinary estradiol and testosterone levels measured by liquid chromatography-mass spectrometry were obtained at three-month intervals for three years. Integrated measures (area-under-curve) of urinary steroid excretion summarised as absolute and variability during each 12-month period of the study. Psychosocial data were gathered annually with the primary outcome of depressive symptomatology. Secondary outcomes were the other subscales of the Youth Self-Report, impulsive-aggression, sleep habits, and self-harm. Results: 277 (158 male) participants contributed data over the full duration of the study and could be included in the analyses. In females, analyses of absolute urine hormone levels found no relationship between estradiol and any outcome, but higher testosterone was significantly associated with depression and poorer sleep. Greater variability of both urine estradiol and testosterone was associated with lower total psychopathology, anxious/depressed and social problems scores. Greater variability in urine estradiol was associated with lower attention problems and impulsive aggression in females. In males, higher testosterone and estradiol levels were associated with rule-breaking, and poorer sleep, and no associations were found for gonadal hormone variability for males. Conclusions: Longitudinal measurement of both iso-sexual and contra-sexual gonadal hormones contributes to a more nuanced view of the impact of sex steroids on mood and behavior in adolescents. These findings may enlighten the understanding of the impact of sex steroids during normal male and female puberty with implications for hormone replacement therapies as well as management of common mood and behavioral problems. [ABSTRACT FROM AUTHOR]

Published
2023
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30. The Future Proofing Study: Design, methods and baseline characteristics of a prospective cohort study of the mental health of Australian adolescents.

Author

Werner‐Seidler, Aliza, Maston, Kate, Calear, Alison L., Batterham, Philip J., Larsen, Mark E., Torok, Michelle, O'Dea, Bridianne, Huckvale, Kit, Beames, Joanne R., Brown, Lyndsay, Fujimoto, Hiroko, Bartholomew, Alexandra, Bal, Debopriyo, Schweizer, Susanne, Skinner, S. Rachel, Steinbeck, Katharine, Ratcliffe, Julie, Oei, Ju‐Lee, Venkatesh, Svetha, and Lingam, Raghu

Subjects
MENTAL health, AUSTRALIANS, TORRES Strait Islanders, ADOLESCENT health, COHORT analysis
Abstract

Objectives: The Future Proofing Study (FPS) was established to examine factors associated with the onset and course of mental health conditions during adolescence. This paper describes the design, methods, and baseline characteristics of the FPS cohort. Methods: The FPS is an Australian school‐based prospective cohort study with an embedded cluster‐randomized controlled trial examining the effects of digital prevention programs on mental health. Data sources include self‐report questionnaires, cognitive functioning, linkage to health and education records, and smartphone sensor data. Participants are assessed annually for 5 years. Results: The baseline cohort (N = 6388, M = 13.9 years) is broadly representative of the Australian adolescent population. The clinical profile of participants is comparable to other population estimates. Overall, 15.1% of the cohort met the clinical threshold for depression, 18.6% for anxiety, 31.6% for psychological distress, and 4.9% for suicidal ideation. These rates were significantly higher in adolescents who identified as female, gender diverse, sexuality diverse, or Aboriginal and/or Torres Strait Islander (all ps < 0.05). Conclusions: This paper provides current and comprehensive data about the status of adolescent mental health in Australia. The FPS cohort is expected to provide significant insights into the risk, protective, and mediating factors associated with development of mental health conditions during adolescence. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Efficacy, safety, and immunogenicity of the human papillomavirus 16/18 AS04-adjuvanted vaccine in women older than 25 years: 4-year interim follow-up of the phase 3, double-blind, randomised controlled VIVIANE study

Author

Skinner, S Rachel, Szarewski, Anne, Romanowski, Barbara, Garland, Suzanne M, Lazcano-Ponce, Eduardo, Salmerón, Jorge, Del Rosario-Raymundo, M Rowena, Verheijen, René H M, Quek, Swee Chong, da Silva, Daniel P, Kitchener, Henry, Fong, Kah Leng, Bouchard, Céline, Money, Deborah M, Ilancheran, Arunachalam, Cruickshank, Margaret E, Levin, Myron J, Chatterjee, Archana, Stapleton, Jack T, Martens, Mark, Quint, Wim, David, Marie-Pierre, Meric, Dorothée, Hardt, Karin, Descamps, Dominique, Geeraerts, Brecht, Struyf, Frank, and Dubin, Gary

Published
2014
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36. Risk of Newly Detected Infections and Cervical Abnormalities in Women Seropositive for Naturally Acquired Human Papillomavirus Type 16/18 Antibodies: Analysis of the Control Arm of PATRICIA

Author

Castellsagué, Xavier, Naud, Paulo, Chow, Song-Nan, Wheeler, Cosette M., Germar, Maria Julieta V., Lehtinen, Matti, Paavonen, Jorma, Jaisamrarn, Unnop, Garland, Suzanne M., Salmerón, Jorge, Apter, Dan, Kitchener, Henry, Teixeira, Julio C., Skinner, S. Rachel, Limson, Genara, Szarewski, Anne, Romanowski, Barbara, Aoki, Fred Y., Schwarz, Tino F., Poppe, Willy A. J., Bosch, F. Xavier, de Carvalho, Newton S., Peters, Klaus, Tjalma, Wiebren A. A., Safaeian, Mahboobeh, Raillard, Alice, Descamps, Dominique, Struyf, Frank, Dubin, Gary, Rosillon, Dominique, and Baril, Laurence

Published
2014

37. 'You Can Help People': Adolescents' Views on Engaging Young People in Longitudinal Research

Author

Robbins, Spring C. Cooper, Rawsthorne, Margot, Paxton, Karen, Hawke, Catherine, Skinner, S. Rachel, and Steinbeck, Katharine

Abstract

We sought to discover adolescents' thoughts about participation in longitudinal research and identify recruitment and retention strategies that were meaningful to them. We conducted seven focus groups with 10-15-year-olds in two large rural centers in New South Wales, Australia, and all focus groups were digitally recorded, transcribed, and analyzed. Adolescents discussed factors salient to their involvement in focus groups, as well as factors that may influence involvement in a longitudinal study. At the outset of the focus groups, adolescents had a positive view of "research," but were reluctant to engage in research that involved biologic samples. Effective recruitment of adolescents requires an appreciation of motivators, and time and resources to extend potential participants' understanding.

Published
2012
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38. How Australian Female Adolescents Prioritize Pregnancy Protection: A Grounded Theory Study of Contraceptive Histories

Author

Smith, Jennifer L., Skinner, S. Rachel, and Fenwick, Jennifer

Abstract

Grounded theory principles were systematically employed to reveal key differences in pregnancy risk and underlying disparities in contraceptive use in (a) never-pregnant (b) pregnant-terminated and (c) pregnant-continued teenagers. Analysis of 69 semistructured interviews revealed a bicausal model of pregnancy protection that accounted for variation in contraceptive use across the sample. Diverging pregnancy/childbearing desires and risk perceptions were conceptualized into three behavioral patterns that represented higher and lower levels of commitment to prevent pregnancy. The various ways that teenagers made sense of their behavior highlight the importance of acknowledging and respecting diversity in perspectives and experiences and provide a useful framework for educational and practitioner-delivered interventions with greater relevance and impact. (Contains 4 tables and 2 figures.)

Published
2011
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40. Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation

Author

Szarewski, Anne, Skinner, S. Rachel, Garland, Suzanne M., Romanowski, Barbara, Schwarz, Tino F., Apter, Dan, Chow, Song-Nan, Paavonen, Jorma, Del Rosario-Raymundo, M. Rowena, Teixeira, Julio C., De Carvalho, Newton S., Castro-Sanchez, Maria, Castellsagué, Xavier, Poppe, Willy A. J., De Sutter, Philippe, Huh, Warner, Chatterjee, Archana, Tjalma, Wiebren A., Ackerman, Ronald T., Martens, Mark, Papp, Kim A., Bajo-Arenas, Jose, Harper, Diane M., Torné, Aureli, David, Marie-Pierre, Struyf, Frank, Lehtinen, Matti, and Dubin, Gary

Published
2013
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42. Prevalence and risk factors for cervical HPV infection and abnormalities in young adult women at enrolment in the multinational PATRICIA trial

Author

Roset Bahmanyar, Edith, Paavonen, Jorma, Naud, Paulo, Salmerón, Jorge, Chow, Song-Nan, Apter, Dan, Kitchener, Henry, Castellsagué, Xavier, Teixeira, Julio C., Skinner, S. Rachel, Jaisamrarn, Unnop, Limson, Genara A., Garland, Suzanne M., Szarewski, Anne, Romanowski, Barbara, Aoki, Fred, Schwarz, Tino F., Poppe, Willy A.J., De Carvalho, Newton S., Harper, Diane M., Bosch, F. Xavier, Raillard, Alice, Descamps, Dominique, Struyf, Frank, Lehtinen, Matti, and Dubin, Gary

Published
2012
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45. Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial

Author

Wheeler, Cosette M, Castellsagué, Xavier, Garland, Suzanne M, Szarewski, Anne, Paavonen, Jorma, Naud, Paulo, Salmerón, Jorge, Chow, Song-Nan, Apter, Dan, Kitchener, Henry, Teixeira, Júlio C, Skinner, S Rachel, Jaisamrarn, Unnop, Limson, Genara, Romanowski, Barbara, Aoki, Fred Y, Schwarz, Tino F, Poppe, Willy A J, Bosch, F Xavier, Harper, Diane M, Huh, Warner, Hardt, Karin, Zahaf, Toufik, Descamps, Dominique, Struyf, Frank, Dubin, Gary, and Lehtinen, Matti

Published
2012
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46. Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial

Author

Lehtinen, Matti, Paavonen, Jorma, Wheeler, Cosette M, Jaisamrarn, Unnop, Garland, Suzanne M, Castellsagué, Xavier, Skinner, S Rachel, Apter, Dan, Naud, Paulo, Salmerón, Jorge, Chow, Song-Nan, Kitchener, Henry, Teixeira, Júlio C, Hedrick, James, Limson, Genara, Szarewski, Anne, Romanowski, Barbara, Aoki, Fred Y, Schwarz, Tino F, Poppe, Willy A J, De Carvalho, Newton S, Germar, Maria Julieta V, Peters, Klaus, Mindel, Adrian, De Sutter, Philippe, Bosch, F Xavier, David, Marie-Pierre, Descamps, Dominique, Struyf, Frank, and Dubin, Gary

Published
2012
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