384 results on '"Simons, Mikael"'
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2. Nonvesicular lipid transfer drives myelin growth in the central nervous system
3. Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer’s disease
4. Associations between sex, body mass index and the individual microglial response in Alzheimer’s disease
5. Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging
6. Microglia states and nomenclature: A field at its crossroads
7. Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis
8. Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
9. Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies
10. Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects
11. Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury
12. Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
13. Tau deposition patterns are associated with functional connectivity in primary tauopathies
14. Tipping points in neurodegeneration
15. Distinct molecular profiles of skull bone marrow in health and neurological disorders
16. A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature
17. CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
18. Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry
19. Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer's disease.
20. Author Correction: Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination
21. Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration.
22. Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain
23. Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution
24. Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination
25. Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis
26. Age-related myelin degradation burdens the clearance function of microglia during aging
27. Protective lifelines: Tunneling nanotubes connect neurons and microglia.
28. Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia
29. Association between altered hippocampal oligodendrocyte number and neuronal circuit structures in schizophrenia: a postmortem analysis
30. Defective cholesterol clearance limits remyelination in the aged central nervous system
31. Neuron to Glia Signaling Triggers Myelin Membrane Exocytosis from Endosomal Storage Sites
32. An optimized quantitative proteomics method establishes the cell type‐resolved mouse brain secretome
33. Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease
34. Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region
35. Assembly of Myelin by Association of Proteolipid Protein with Cholesterol- and Galactosylceramide-Rich Membrane Domains
36. Cholesterol Depletion Inhibits the Generation of β -amyloid in Hippocampal Neurons
37. Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model
38. Intracellular and Secreted Alzheimer β -Amyloid Species are Generated by Distinct Mechanisms in Cultured Hippocampal Neurons
39. Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients
40. Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS
41. BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions
42. A new role for oligodendrocytes and myelination in schizophrenia and affective disorders?
43. Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
44. Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions
45. Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system
46. Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2
47. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation
48. Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A—C
49. Efficient Inhibition of the Alzheimer's Disease β-Secretase by Membrane Targeting
50. Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
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