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Start Over Author "Sigrid Pedersen" Publication Type Academic Journals
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1. Decreased serum concentrations of antiseizure medications in children with drug resistant epilepsy following treatment with ketogenic diet

Author

Sigrid Pedersen, Magnhild Kverneland, Knut Rudi, Kristina Gervin, Cecilie Johannessen Landmark, Per Ole Iversen, and Kaja Kristine Selmer

Subjects
antiseizure medications, dietary treatment, food‐drug interactions, high‐fat, low‐carbohydrate diet, therapeutic drug monitoring, Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Objective To examine the potential influence of a ketogenic diet on serum concentrations of antiseizure medications (ASMs) in children with drug resistant epilepsy. Methods We investigated the serum concentrations of ASMs in 25 children with drug resistant epilepsy, 2–13 years of age, treated with a classical ketogenic diet for 12 weeks. The patients were recruited from the National Centre for Epilepsy from August 15th, 2017, to January 24th, 2022. Changes in ASM serum concentrations were analyzed using a mixed effect model analysis. Significance level was set at P

Published
2023
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