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Fungi are among the most diverse and ecologically important kingdoms in life. However, the distributional ranges of fungi remain largely unknown as do the ecological mechanisms that shape their distributions1,2. To provide an integrated view of the spatial and seasonal dynamics of fungi, we implemented a globally distributed standardized aerial sampling of fungal spores3. The vast majority of operational taxonomic units were detected within only one climatic zone, and the spatiotemporal patterns of species richness and community composition were mostly explained by annual mean air temperature. Tropical regions hosted the highest fungal diversity except for lichenized, ericoid mycorrhizal and ectomycorrhizal fungi, which reached their peak diversity in temperate regions. The sensitivity in climatic responses was associated with phylogenetic relatedness, suggesting that large-scale distributions of some fungal groups are partially constrained by their ancestral niche. There was a strong phylogenetic signal in seasonal sensitivity, suggesting that some groups of fungi have retained their ancestral trait of sporulating for only a short period. Overall, our results show that the hyperdiverse kingdom of fungi follows globally highly predictable spatial and temporal dynamics, with seasonality in both species richness and community composition increasing with latitude. Our study reports patterns resembling those described for other major groups of organisms, thus making a major contribution to the long-standing debate on whether organisms with a microbial lifestyle follow the global biodiversity paradigms known for macroorganisms4,5.

Novel methods for sampling and characterizing biodiversity hold great promise for re-evaluating patterns of life across the planet. The sampling of airborne spores with a cyclone sampler, and the sequencing of their DNA, have been suggested as an efficient and well-calibrated tool for surveying fungal diversity across various environments. Here we present data originating from the Global Spore Sampling Project, comprising 2,768 samples collected during two years at 47 outdoor locations across the world. Each sample represents fungal DNA extracted from 24 m3 of air. We applied a conservative bioinformatics pipeline that filtered out sequences that did not show strong evidence of representing a fungal species. The pipeline yielded 27,954 species-level operational taxonomic units (OTUs). Each OTU is accompanied by a probabilistic taxonomic classification, validated through comparison with expert evaluations. To examine the potential of the data for ecological analyses, we partitioned the variation in species distributions into spatial and seasonal components, showing a strong effect of the annual mean temperature on community composition.

The research focuses on the automatic annotation of a linguistic corpus using large language models (LLMs). Annotating a corpus is a crucial step in its creation, as it determines the practical scope and applications of the resource being developed. This study explores the annotation of oral speech transcripts at the pragmatic level using speech acts that reflect the speaker's intent and purpose. Typically, this task is performed manually by experts, which greatly limits the volume of annotated data that can be produced. In this work, an attempt was made to automatically annotate speech acts using five LLMs commonly used for processing Russian texts – ChatGPT, GigaCHAT, YandexGPT, Mistral, and Gemini. A comparative analysis of the automatic annotation results was conducted, highlighting the strengths and weaknesses of each model. . The findings suggest that employing LLMs for corpus annotation is a promising approach, with ChatGPT and Gemini demonstrating particular effectiveness in speech act categorization. However, for Russian, language-specific models like GigaCHAT and YandexGPT are preferred when language-specific information is needed.

Abstract Cesarean section for breech presentation is often recommended. However, cesarean section affects future reproduction. The aim of this study was to assess the effect of mode of the first birth in breech on outcomes of the second birth and the two births together. This is a register-based nationwide cohort study including 23 062 women with a first singleton birth in breech ≥ 34 gestational weeks and a subsequent singleton birth in Sweden 2000–2019. Exposure was mode of first delivery. Main maternal outcome was a composite of fourth-degree perineal injury, postpartum hemorrhage requiring blood transfusion, hysterectomy, or death. Main infant outcome was a composite of stillbirth, extremely preterm birth (

Introduction. The most important stage of pharmaceutical development of a generic drug is a clinical trial involving humans – a bioequivalence study. Considering the importance of finding rivaroxaban drugs in the list of vital and essential drugs, as part of ensuring technological sovereignty, the use of scientific robust and effective methods for determining the quality of the dosage form is required.Aim. Conduct a study of rivaroxaban tablets on a physiologically relevant tester to predict pharmacokinetic profiles.Materials and methods. The objects of the study are "Xarelto®, film-coated tablets, 10 mg" (series BXJS871, with an expiration date of October 31, 2024, Bayer AG, Germany), "Xarelto®, film-coated tablets, 20 mg" (series BXKDF32, with an expiration date of May 17, 2026, Bayer AG, Germany) and "Rivaroxaban, film-coated tablets, 10 mg" and "Rivaroxaban, film-coated tablets, 20 mg", domestically produced, with valid expiration dates. During the study, reagents were used to prepare dissolution media and perform quantitative determination. The physiologically relevant test was performed on the SC PRT-6 device (LLC "Scientific Compliance", Russia). The quantitative content of released rivaroxaban within the comparative dissolution kinetics test in a medium of 0.1 in a medium of 0.1 % sodium lauryl sulfate solution in a phosphate buffer solution pH 6.5 was carried out on a SF-2000 spectrophotometer (LLC "OKB Spektr", Russia). The quantitative content of released rivaroxaban within the comparative dissolution kinetics test in biorelevant dissolution media and physiological relevance test was assessed on a high-performance liquid chromatograph "Chromatec-Crystal HPLC 2014" (CJSC "Chromatec", Russia). Pharmacokinetic profiles were modeled in the PK-Sim® (Systems Biology Software Suite 11.2, Bayer Technology Services GmbH, Germany) program based on the data obtained within the physiologically relevant test. The clinical study of rivaroxaban tablets was a prospective, open-label, randomized, crossover, two-stage comparative study in two groups of volunteers with a single dose of drugs on the fast condition. The study randomized 30 healthy male volunteers aged 18–45 years.Results and discussion. A complex of in vitro tests was conducted, profiles were obtained that allow us to evaluate the dynamics and degree of release of the studied drugs in various parts of the human gastrointestinal tract. A comparison of the sequential and hybrid schemes for conducting the physiological relevance test was carried out. Within the framework of the set of tests, qualitative and quantitative correlation with the clinical trials data was observed only for the hybrid physiological relevance test scheme. Based on the results of physiological relevance test using different schemes, pharmacokinetic profiles for a pair of drugs were predicted and the prediction error was assessed.Conclusion. A set of scientific in vitro tests was conducted for the drugs "Xarelto®, film-coated tablets, 10 mg and 20 mg", "Rivaroxaban, film-coated tablets, 10 mg and 20 mg". Based on the physiological relevance test results, pharmacokinetic profiles for a pair of drugs were predicted with low error and high reliability. As part of the comparison of data obtained during clinical trial and modeling, the smallest prediction error was noted when performing physiological relevance test using a hybrid scheme.

Relevance. Aging is anatural biological process of aretrograde nature, during which there is an imbalance of all systems, including the matrix metalloproteinase (MMP) system and tissue inhibitors of matrix metalloproteinases (TIMP). And vascular aging is associated with functional and structural changes primarily in the arterial vasculature with age. Aging may be atrigger factor for pathological changes in the endothelium. The molecular mechanisms underlying the process of vascular endothelial dysfunction include increased expression and activation of matrix metalloproteinases, the concentration of which changes with aging. Numerous studies report the role of MMP-1,–2,–9,–12 in the pathogenesis of premature aging of the endothelium; they initiate cell apoptosis, which contributes to increased permeability, but there are no studies in which all age categories of both men and women were analyzed, not burdened by somatic pathology. This study examines the features of the proteolysis/antiproteolysis system in apparently healthy people of different ages and genders.Materials and Methods.As part of the pilot study, 347 apparently healthy people took part (226 women and 121 men, divided by age, according to the WHO classification), who underwent the first stage of clinical examination at the State Budgetary Institution “Consultative and Diagnostic Center of the Mountains. Yuzhno-­Sakhalinsk”, in which the level of MMP and TIMP in the blood serum was determined by solid-­phase ELISA, ng/ml. Statistical processing of the research results was carried out using the IBM SPSS Statistics Version 25.0 software package.Resultsand Discussion.Changes in the proteolysis/antiproteolysis system were determined in both agroup of men and women of different ages, which can be characterized as not pathological, but close to such. It was found that in men aged 60-74 years, discoordinated work of matrix metalloproteinases and their inhibitors was recorded in the direction of enhancing the profibrosing effect, and in women in the same age category, the exact opposite component was identified—anti-fibrosing.Conclusion.The current development has demonstrated the influence of age and genetic resources on the system of matrix metalloproteinases and their tissue inhibitors, in addition, aspecial age group has been identified—the elderly group, which requires protection of the vascular system in order to monitor the impaired proteolysis/antiproteolysis system.

Objective: to assess the prognostic significance of antibodies to the NR2 subunit of the N-methyl-D-aspartate (NMDA) glutamate receptor and brain natriuretic propeptide (NTproBNP) as predictors of unfavorable neurological outcomes in premature children.Materials and methods: A prospective cohort continuous study included 151 premature children, with a gestational age (GA) of 26–32 weeks and a body weight of 590–1990 gr. The children were measured the quantitation of NTproBNP level in the cord blood and level of antibodies to the NR2 subunit of the N-methyl-D-aspartate (NMDA) glutamate receptor in the blood serum on the 21st day of life. The division of children into groups was carried out in accordance with the assessment of neurological outcomes at control points of the research: 1 control point — at the time of discharge from the hospital, 2 control point — at the age of 1 year of corrected age (CA), 3 control point — 4 years of life.Results: in the course of the study, it was found a “cascade” increase in the cohort of children with unfavorable neurological outcomes from 36.4% at the time of discharge from the hospital to 70% by the age of 4 years. High values of NT-proBNP level in cord blood and antibodies to the NR2 subunit of the N-methyl-D-aspartate (NMDA) glutamate receptor were established on 21st day of postnatal life in children with both macrostructural brain damages in the neonatal period and having an unfavorable neurological outcome at the age of 1 year of corrected age (CA) and at 4 years of life.Conclusion: modern neurochemical markers of CNS damages N-proBNP and antibodies to the NR2 subunit of the N-methyl-D-aspartate (NMDA) glutamate receptor open up the possibilities of early diagnosis of brain damages at the cellular level and the start of neuroprotective therapy to reduce neurological disability.

The dynamic development of technologies in highly automated vehicles requires the development of new methods for transmitting information on board a vehicle in a timely and efficient manner. In this regard, the direction of data transmission over the air is actively developing. The article considers cloud services that can be used for over-the-air updates in highly automated vehicles. The main, most used and additional cloud services are highlighted. The provider and client responsibility scheme for cloud services IaaS, PaaS, SaaS is presented. The aspects of security of cloud services are considered as one of the most important and priority tasks to prevent threats and protect personal data. Specific categories of over-the-air updates used in highly automated vehicles and adjacent infrastructure are presented and described. The process of releasing and installing firmware and software updates over-the-air on highly automated vehicles, their components and adjacent infrastructure is considered. The results obtained are oriented towards a deeper understanding of the over-the-air software upgrade process.

Transcription factor (TF)-based biosensors that connect small-molecule sensing with readouts such as fluorescence have proven to be useful synthetic biology tools for applications in biotechnology. However, the development of specific TF-based biosensors is hindered by the limited repertoire of TFs specific for molecules of interest since current construction methods rely on a limited set of characterized TFs. In this study, we present an approach for engineering the specificity of TFs through a computation-based workflow using molecular docking that enables targeted alteration of TF ligand specificity. Using this method, we engineer the LysR family BenM TF to alter its specificity from its cognate ligand cis,cis-muconic acid to adipic acid through a single amino acid substitution identified by our computational workflow. When implemented in a cell-free system, the engineered biosensor shows higher ligand sensitivity, expanding the potential applications of this circuit. We further investigate ligand binding through molecular dynamics to analyze the substitution, elucidating the impact of modulating a single amino acid position on the mechanism of BenM ligand binding. This study represents the first application of biomolecular modeling methods for altering BenM specificity and for gaining insights into how mutations influence the structural dynamics of BenM. Such methods can potentially be applied to other TFs to alter specificity and analyze the dynamics responsible for these changes, highlighting the applicability of computational tools for informing experiments. In addition, our developed adipic acid biosensor can be applied for the identification and engineering of enzymes to produce adipic acid.

The objective of this study was to analyze the fatty acid composition of five strains from the genera Chlorella, Micractinium, and Meyerella and conduct an initial assessment of their biotechnological potential. It was found that the strain C. vulgaris VKM Al-335 is a good producer of palmitic acid, the Micractinium strains VKM Al-332 and VKM Al-343 are rich in ω-3 fatty acids, whereas the Meyerella strains VKM Al-346 and VKM Al-428 are producers of ω-6 fatty acids. A comparison of the biotechnological potential of algae with that of higher plant leaves (wheat) demonstrates that algal fatty acids exhibit greater diversity, although it is inferior to wheat leaves in terms of polyunsaturated and ω-3 fatty acids. Correlation analysis showed that when only straight-chain fatty acids were considered, the strains were distributed on the principal component analysis plot in accordance with their genetic relationships. However, when the entire fatty acid profile, inclusive of minor branched-chain and cyclic fatty acids, was analyzed, the algae distribution was in accordance with the environmental conditions in the original habitat, suggesting a possible connection between branched-chain and cyclic fatty acids and microalgae adaptability to environmental temperature conditions.

Currently, the issues of studying the quantitative assessment of the isolated effects of physical and chemical occupational factors of low intensity, severity and intensity of the labor process on the telomere relative length (TRL) are relevant in order to establish the mechanisms of development of premature aging. The aim is to evaluate the effect of isolated exposure to low–intensity physical and chemical occupational factors on the relative length of telomeres in an animal experiment. Material and methods. ICR mice (n = 65) are distributed in equal numbers into 3 test groups (exposure to vibration, noise, chemical exposure) and 1 control group (contained in comfortable conditions and not exposed to these factors). The duration of the experiment was 90 days, samples for DNA isolation from the striated muscle tissue of ICR mice thigh were taken on days 0, 30, 60 and 90. TRL was measured using real time PCR. Results and discussion. The results of the study indicate a significant shortening of TRL on the 90th day in the control group compared to the initial indicators, which may indicate the general processes of aging of animals. A long (90-day) stay of ICR mice in conditions simulating the isolated influence of various occupational hazard factors (vibration, noise, chemicals) operating at a level of 1.5 MAC, MPL, was accompanied by unidirectional dynamics of TRL. The chemical factor has the greatest impact on TDC (a decrease in TDT relative to the value of the control group is noted on the 30th, 60th and 90th days of the experiment), the physical factor causes a shortening of TDT after 60 and 90 days. Conclusions. Further study of the isolated influence of occupational factors on the TRL change in model organisms will contribute to the establishment of mechanisms that prevent the development of pathological processes in workers under conditions of production hazards.

The main indicators of food security are initially formed at the regional level while being oriented on the macroeconomy. The new subjects of the Russian Federation have to develop under a constant military threat. This situation makes it important for the state to monitor their self-sufficiency in food products, which must be physically and economically available to the population. The authors assessed the current and prospective sustainability and availability of food in the Donetsk People’s Republic. The structure and elements of food security and food supply were analyzed in line with the Doctrine of Food Security of the Russian Federation. The article described the level of self- sufficiency in basic food products, the level of agricultural supply, and the level of processing relative to the consumption standards. The economic accessibility of food products was subjected to the comparative method based onthe minimal income level and the cost of living by the minimum consumption standards for each category of population. The cost of the consumer goods basket in 2015-2023 was analyzed demographically. The study proved that food security can be achieved by raising people’s income. Based on an expert survey and brainstorming, the authors developed a response matrix to potential risks and their consequences regarding the state administration of food security.

One of the main way for the study of acting can be considered the process of training student-actors, in which the mechanisms and techniques of creating an image and assuming a role are unfolded and highlighted. Special attention in the study of this problematic should be paid to the factors contributing to the mastery of the profession. It is assumed that personal characteristics play a key role in the issue of successful training of a student-actor, because it is the actor's personality that can be considered as the main tool that the actor has in the art of acting transformation. The aim is to identify personal predictors of pedagogical assessments of acting abilities among student actors. Psychodiagnostic study using the following techniques: “16 personality factors” by R. Kettell and “Short portrait questionnaire of the Big Five” by M.S. Egorova and O.V. Parshikova, the scale of average assessments of acting abilities. It was revealed that two personality traits are associated with the pedagogical assessment of the acting skills of an actor student: “consciousness” (B5-10) and “sensitivity” (I, 16PF). They also contribute to this average estimate. In this regard important factors for the success of mastering the acting profession are consciousness, organization, focus on maintaining relationships in the learning process, as well as the sensitivity of the student actor to internal and external changes, the richness of his emotional experience.

Aim. To evaluate the efficacy and toxicity of second-line polychemotherapy according to FOLFOX or FOLFIRI regimen in patients with biliary tract tumours after progression during first-line chemotherapy (CT). Materials and methods. The study is based on the analysis of retrospective and prospective data on the examination and treatment of 94 patients with biliary cancer of grades T1-4N0-2M0-1 followed-up and treated at the N.N. Blokhin National Medical Research Center of Oncology from 2015 to 2023. All patients were divided into 2 groups: Group 1 (FOLFOX, n=47) and Group 2 (FOLFIRI, n=47). In Group 1, patients received the recommended FOLFOX second-line CT regimen. Patients in Group 2 received FOLFIRI regimen. The endpoints were overall survival (OS) and incidence of grade 3-4 adverse events. Results. The study included 94 patients. In the FOLFOX group, the median OS was 13.0 months (1-year OS was 57.8±7.4%); for the FOLFIRI group, the median OS was 12.3 months (1-year OS was 54.4±7.3%). The toxicity profiles of FOLFOX and FOLFIRI were acceptable and consistent with those reported for the regimens. According to the grade 3–4 toxicity data, diarrhea was significantly more common in the FOLFIRI group (p=0.014), and neurotoxicity was more common in the FOLFOX group (p=0.006). During the second-line CT, the frequency of grade 1–4 toxicities in the groups did not differ: 18 (38.3%) events in the FOLFOX group and 19 (40.0%) events in the FOLFIRI group. Conclusion. Our results of evaluating the efficacy and toxicity of the second-line polychemotherapy regimens show that the FOLFOX and FOLFIRI CT regimens have equal efficacy in patients with advanced biliary tract cancer with a good performance according to the ECOG scale, who previously received the first-line therapy with a combination of gemcitabine with a platinum agent (cisplatin or oxaliplatin); also, our data demonstrate similar toxicity profiles of these regimens.

Relevance. Oenothera tetragona is an ornamental plant used in folk medicine. Until now, studies of the biological characteristics of the Oenothera tetragona have not been carried out on the territory of the NonChernozem zone of the Russian Federation.The purpose of the work is the introduction and biological study of the Oenothera tetragona in the NonChernozem zone of Russia in the conditions of the Moscow region.Methodology. The experiment was based on two-month-old seedlings according to a 60x30 cm pattern. Phenological observations and biometric measurements (during the mass flowering phase) were carried out according to the methods adopted at VILAR (All-Russian scientific research Institute of medicinal and aromatic plants). Experimental data were processed according to B.A. Dospehov. Weather conditions were checked on the Weather and Climate website. Microspecimens were prepared according to methods for light microscopy.Results. In the conditions of the Moscow region the period from the beginning of the growing season to mass fruiting in Oenothera tetragona Roth. averages about 110-115 days. The plant is well adapted: it goes through the entire seasonal cycle of growth and development. The population includes Oenothera tetragona Roth. includes many variable biotypes, which indicates the possibility of targeted selection of forms with useful traits. The main assessment of breeding material can be carried out, starting from the second year of plant life, based on a set of interrelated quantitative traits (height, number of generative shoots, etc.). Some anatomical features of the epidermis of the Oenothera tetragona leaf have been studied for the first time; the number of covering trichomes and the number of stomata per 1 mm2 were determined. As a result of microscopic examination of the epidermis of leaf plates of O. tetragona Roth.: the presence of three groups was revealed, which differed in microscopic characteristics (shape and number of stomata, pubescence) in the absence of a noticeable correlation with the main phenotypic characteristics.

Quantitative characteristics of the impact of factors of the production environment (physical, chemical, biological), the severity and intensity of the labor process, their contribution to the deterioration of the health of the working contingent and the development of mechanisms of premature aging can hardly be overestimated. Occupational factors play a leading role among the health risk factors of the labor contingent in the workplace. Their effect on the organism of people engaged in work with harmful and (or) dangerous working conditions can have cumulative effect on the health of workers and cause premature aging of the body, exert an adverse effect on the central nervous, cardiovascular, endocrine, reproductive, digestive, excretory, blood, musculoskeletal system, causing psychosomatic, acute and chronic occupational diseases, and poisoning. Long-term chronic “occupational” and domestic stress prevails among the mechanisms that reveal premature aging at the level of the hypothalamic-pituitary-adrenal axis. The article analyzes (according to literature sources) the most probable risk factors and mechanisms that trigger the processes of premature aging.

Immune relationships involved in a wide range of immunopathological conditions, including ankylosing spondylitis (AS), are formed due to the characteristics of the subset composition of follicular T helper cells (Tfh) and B lymphocytes. Expression of the HLA-B27 antigen can change the reactivity of cells of the immune system and, accordingly, their interaction and participation in the immunopathogenesis of AS. The aim of this study was to investigate the characteristics of the subset composition of Tfh and B cells in HLA-B27-positive and negative patients with AS. Material and methods. 66 patients (17 women and 49 men) aged 20–58 years with a diagnosis of AS were examined. Molecular genetic research on HLA-B27 expression was carried out using the quantitative PCR method with real-time detection. The subset composition of Tfh and B cells was studied using flow cytometry. Results. An increase in the amount of Tfh2 in the blood is observed in all patients with AS. The number of Tfh1 was reduced in HLA-B27-positive AS patients, but Tfh17 cell content was increased. Changes in the subset composition of B lymphocytes, which were found only in patients with an HLA-B27-positive form of the disease, manifest themselves primarily as an imbalance in the distribution of B cell memory. Only negative correlations of Tfh1 and Tfh17 content with “double-negative” B cell and plasmablast precursors percentage are detected in HLA-B27-negative AS patients. Tfh1 cell number correlate negatively with naïve and activated naïve B cell content in HLA-B27-positive disease, Tfh2 cell percentage – with memory B cell fraction number. CCR6+ Tfh and Tfh17 have positive regulatory effects on plasmablast precursors. Conclusions. The subset composition of Tfh characterizes the dominance in the immunopathogenesis of AS of the direction of the regulatory influence of follicular T helper cells on B lymphocytes regardless of the carriage of the HLA-B27 gene in AS patients. High levels of Tfh type 17 are also detected in HLA-B27-positive patients. The relationships between the subsets of Tfh and B cells in HLA-B27-negative AS patients characterize the presence of processes aimed at inhibiting B cells. The influence of Tfh1 is aimed at suppression of B-cell immunity in HLA-B27-positive AS while Tfh2 and Tfh17 stimulate B-cell mechanisms.

The relevance of the research is justified by the need to search for new factors of business value formation, which are taken into account by stakeholders when making decisions. The purpose of the article is to analyze the influence of S- and G- factors on the value formation of Russian public companies in the manufacturing sector and to substantiate the importance of disclosing the indicators of sustainable development of companies as a factor of business growth. The study uses methods and tools of correlation, causal and comparative analysis. It was found that the position occupied in the RAEX ranking by S- and G- factors and the amount of capitalization are significantly correlated for companies in the extractive and manufacturing industries. There was found no statistically significant relationship between the considered indicators in relation to the companies of the agro-industrial complex. It is confirmed that the influence of sustainable development components on the formation of the companies’ value is different depending on their industry affiliation. The necessity to take into account ESG factors in the methods of comparative and income approaches is substantiated. The directions of ESG factors accounting in the methods of comparative and income approaches are highlighted. The scientific novelty of the research is determined by the substantiation of the necessity of separate accounting of the sustainable development components in the formation and assessment of business value. The practical significance of the study is that the results obtained by the author can be used by investors, owners and practicing appraisers in making managerial decisions and assessing and determining business value.

Background. There is a contradiction in the results of acting research: empathy plays an important role in the process of artistic transformation, but some anti-empathic traits, such as narcissism and machiavellianism, may also be useful for stage performance. The identification of gender specificity is particularly interesting when examining these personal features in the context of student actors' professional growth. Objectives. The focus is on exploring gender differences in the relationships of empathy and Dark Triad traits with personality traits in student actors. Study Participants. The study involved 43 second-year students of the Acting major, aged 19 to 29 years (21 men, 22 women). Methods. Short Portrait Big Five Questionnaire by M.S. Egorova and O.V. Parshikova, Short questionnaire of the Dark Triad adapted by M.S. Egorova, M.A. Sitnikova, O.V. Parshikova Empathy Questionnaire by A.A. Mehrabian adapted by E.F. Zeer and O.N. Shakhmatova Results. Openness to experience among student actors is associated with narcissism, and neuroticism is associated with emotional empathy, which describes the ability to understand other people's emotions. At the same time, gender differences were found in the specific relationships between empathic tendencies and personality traits. In boys, behavioral empathy, aimed at showing support and help, is associated with extraversion, while in girls, neuroticism is associated with machiavellianism. Conclusions. Several interpretations of the results are presented. Actors who are open to new experiences and experiments in creating images can be narcissistic, since they do not yet have a formed “sense of truth”, and therefore are forced to focus more on external assessment. Also, student actors may feel somewhat exceptional compared to their peers due to the experience gained through their professional activities. The connection between the emotional level of empathy in student actors of both sexes and neuroticism is explained by the fact that good social insight is accompanied by increased anxiety. Gender specific correlations (Machiavellianism with neuroticism in girls and behavioral empathy with extraversion in boys) may reflect the chosen strategies in developing the emotional component of the image, as well as in building relationships in a team.

The issues of interlingual Slavic homonymy are being examinedi n a multifaceted way on the material of the East, West and South Slavic languages. Given research problem is one of the most actual in comparative linguistics, translation studies, as well as in the practice of teaching Slavic languages. On specific examples cases of manifestation of homonymy are analysed, the causes of its occurrence are studied, the character, linguistic, as well as extralinguistic factors that accompany this semantic phenomenon are described. Among other things, unlike most scientific works devoted to this topic, the problem we touch on is considered at all basic levels of the language: phonetics, vocabulary, morphology, syntax, stylistics, and phraseology, a theoretical substantiation of the reasons for the appearance of homonyms in the language (resp. languages) is given. Special attention is paid to full and partial homonyms, which developed on the basis of both phonetic and etymological-semantic commonality of vocabulary or, conversely, accidentally coincided in pronunciation. It should be emphasized the relevance of this problem andi ts scientific and practical significance in the framework of the contrastive study of closely related languages, which is also of particular importance for the theoretical study and practical solution of linguistic and cultural issues of the Slavic community, which, in comparison with other Indo- European language groups, disintegrated relatively late (V-VI centuries AD). Despite the fact thatm uch attention is paid to this problem in Slavic studies, and many works are devoted to describing cases of interlingual Slavic homonymy, including dictionaries fixing homonyms in two or several languages, the importance of this study lies precisely in the fact that its main goal has become a broad linguistic review with the maximum possible coverage of all three groups of Slavic languages - starting with Russian and Ukrainian in the East, Polish, Czech and Slovak in the West, Serbian, Croatian, Bulgarian in the South of the Slavic World and ending with its “periphery” - Slovenian in its South West. As tertium comparationis for the authors of the proposed study is the genetic commonality, genetic relationship of the Slavic languages and, accordingly, the etymological relationship of their lexical structures. The article presents some of the most illustrative, commonand frequent homonyms, including that of representing the translation problem of the so-called “false friends of the translator”. Although the general list of examined homonyms is far from exhaustive, the materials of the article can serve as a solid theoretical and practical basis for creating a fundamental dictionary of interlingual Slavic homonyms.