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Your search keyword '"Sasaki, Takashi"' showing total 1,995 results
Start Over Author "Sasaki, Takashi" Publication Type Academic Journals
1,995 results on '"Sasaki, Takashi"'

1. Efficacy and Safety of Durvalumab/Tremelimumab in Unresectable Hepatocellular Carcinoma as Immune Checkpoint Inhibitor Rechallenge Following Atezolizumab/Bevacizumab Treatment

Author

Sho, Takuya, Suda, Goki, Ohara, Masatsugu, Kohya, Risako, Sasaki, Takashi, Yoshida, Sonoe, Hosoda, Shunichi, Ogawa, Koji, Kitagataya, Takashi, Maehara, Osamu, Ohnishi, Shunsuke, Kawagishi, Naoki, Natsuizaka, Mitsuteru, Nakai, Masato, Baba, Masaru, Yamamoto, Yoshiya, Tsukuda, Yoko, Meguro, Takashi, Yamada, Ren, Kobayashi, Tomoe, Takagi, Tomofumi, and Sakamoto, Naoya

Published
2024
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7. Caveolin-1 expression is a predictor of survival and recurrence patterns in resected pancreatic ductal adenocarcinoma

Author

Hirose, Yuki, Oba, Atsushi, Takamatsu, Manabu, Hamada, Tsuyoshi, Takeda, Tsuyoshi, Suzuki, Tatsunori, Maekawa, Aya, Kitano, Yuki, Sato, Shoki, Kobayashi, Kosuke, Omiya, Kojiro, Ono, Yoshihiro, Sato, Takafumi, Ito, Hiromichi, Sasaki, Takashi, Ozaka, Masato, Takeuchi, Kengo, Sasahira, Naoki, Inoue, Yosuke, Wakai, Toshifumi, and Takahashi, Yu

Published
2024
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14. Long-Term Outcomes of Infantile Sacrococcygeal Teratoma: Results from a Multi-Institutional Retrospective Observational Study in Japan

Author

Kano, Motohiro, Tomita, Hirofumi, Sasaki, Takashi, Inoue, Maho, Yamoto, Shinya, Hatata, Tomoko, Nakagawa, Yoichi, Endo, Naobumi, Touma, Miki, Nakata, Mitsuyuki, Tamura, Ryo, Kawakubo, Naonori, Shinkai, Toko, Yoshida, Mariko, Tanaka, Shuichi, Kurobe, Masashi, Watanabe, Ryo, Fukuhara, Masahiro, Tsuji, Yuki, Kato, Yoshihiro, Arai, Yuhki, Fumino, Shigehisa, Hirohata, Yoshiaki, Takayama, Shohei, Tajiri, Tatsuro, Usui, Noriaki, and Taguchi, Tomoaki

Published
2024
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25. “Conversion surgery” for locally advanced pancreatic cancer: A position paper by the study group at the joint meeting of the International Association of Pancreatology (IAP) & Japan Pancreas Society (JPS) 2022

Author

Oba, Atsushi, Del Chiaro, Marco, Fujii, Tsutomu, Okano, Keiichi, Stoop, Thomas F., Wu, Y.H. Andrew, Maekawa, Aya, Yoshida, Yuta, Hashimoto, Daisuke, Sugawara, Toshitaka, Inoue, Yosuke, Tanabe, Minoru, Sho, Masayuki, Sasaki, Takashi, Takahashi, Yu, Matsumoto, Ippei, Sasahira, Naoki, Nagakawa, Yuichi, Satoi, Sohei, Schulick, Richard D., Yoon, Yoo-Seok, He, Jin, Jang, Jin-Young, Wolfgang, Christopher L., Hackert, Thilo, Besselink, Marc G., Takaori, Kyoichi, and Takeyama, Yoshifumi

Published
2023
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33. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways

Author

Yamasaki, Tomohiro, Horie, Takahiro, Koyama, Satoshi, Nakao, Tetsushi, Baba, Osamu, Kimura, Masahiro, Sowa, Naoya, Sakamoto, Kazuhisa, Yamazaki, Kazuhiro, Obika, Satoshi, Kasahara, Yuuya, Kotera, Jun, Oka, Kozo, Fujita, Ryo, Sasaki, Takashi, Takemiya, Akihiro, Hasegawa, Koji, Minatoya, Kenji, Kimura, Takeshi, and Ono, Koh

Published
2022
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37. Positivity of high‐sensitivity HBsAg test, not previous HBV infection, indicates poor prognosis in patients with non‐HBV‐related HCC.

Author

Yasuura, Naohiro, Suda, Goki, Ohara, Masatsugu, Meno, Akimitsu, Sho, Takuya, Kohya, Risako, Sasaki, Takashi, Yoda, Tomoka, Yoshida, Sonoe, Fu, Qingjie, Yang, Zijian, Hosoda, Shunichi, Maehara, Osamu, Ohnishi, Shunsuke, Saitou, Tomoya, Sugiyama, Masaya, Fukuhara, Takasuke, Baba, Masaru, Kitagataya, Takashi, and Kawagishi, Naoki

Subjects
HEPATITIS B, OVERALL survival, HEPATOCELLULAR carcinoma, SUBGROUP analysis (Experimental design), ETIOLOGY of diseases
Abstract

Summary: Background and Aims: The prognostic impact of previous‐HBV‐infection (pHBV) in non‐HBV‐related hepatocellular carcinoma (non‐HBV‐related‐HCC) and the prevalence, characteristics and significance of recently developed high‐sensitivity HBs antigen positivity (hHBsAg+) in these patients remain unclear. We aimed to close these gaps. Methods: We retrospectively screened patients with newly diagnosed non‐HBV‐related‐HCC (standard HBsAg‐test negative) at Hokkaido University. Patients with complete clinical information and preserved serum for hHBsAg+ were included. We evaluated the prevalence, characteristics and prognostic impact of pHBV and hHBsAg+ in non‐HBV‐related‐HCC. Results: A total of 401 non‐HBV‐related‐HCC patients were included (288 with pHBV/113 without pHBV). In non‐HBV‐related‐HCC, pHBV did not affect overall survival (OS). Among non‐HBV‐related‐HCC patients with pHBV, 11.8% (34/288) were hHBsAg+ and had more advanced stages of HCC, higher AFP levels, higher vascular invasion rates, and significantly shorter OS than others (OS: 19.3 vs. 61.4 months, p = 0.012). Comparison of OS among non‐HBV‐related‐HCC patients without pHBV (group 1), those with pHBV and without hHBsAg+ (group 2), and those with pHBV and hHBsAg+ (group 3) revealed significantly shorter OS in group 3 (19.3, 56.6 and 66.4 months in groups 1, 2 and 3, respectively; p = 0.036). Multivariate Cox regression indicated that compared with group 1, only group 3 was significantly and independently associated with shorter OS (HR: 2.044, p = 0.011). Subgroup analysis revealed that this association was particularly evident in non‐HBV‐related‐HCC patients with non‐B‐non‐C aetiology and advanced HCC. Conclusions: In non‐HBV‐related‐HCC patients, hHBsAg+, not pHBV, is significantly and independently associated with poor prognosis. [ABSTRACT FROM AUTHOR]

Published
2024
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38. Determinants of polydoctoring among multimorbid older adults; a cross‐sectional study in an urban area of Japan.

Author

Ando, Takayuki, Sasaki, Takashi, Abe, Yukiko, Nishimoto, Yoshinori, Hirata, Takumi, Haruta, Junji, and Arai, Yasumichi

Abstract

Background: Multimorbidity increases with age, leading to various adverse outcomes, including higher mortality, care dependency, hospitalizations, and healthcare costs. Polydoctoring, managing a patient with multimorbidity by multiple healthcare providers, can be a risk of fragmented care and increased healthcare expenditures. This study aims to identify patient‐related factors contributing to polydoctoring in older adults with multimorbidity. Methods: This study is a cross‐sectional study using baseline data from the Kawasaki Aging and Wellbeing Project. Participants were residents of Kawasaki City aged 85–89 years, without disability in basic activities of daily living, and being able to visit study site. The regularly visited facilities (RVF) index was employed to quantify polydoctoring. Polydoctoring was defined as having two or more RVFs. Poisson regression analysis was conducted to assess the association between polydoctoring and patient demographics, including types of chronic conditions and socioeconomic factors. Results: A total of, 968 participants with multimorbidity were analyzed. Increased RVF was significantly associated with eye diseases (rate ratio [RR] 1.27, 95% confidence interval [CI] 1.12–1.44), osteoporosis (RR 1.22, 95% CI 1.08–1.38), prostate diseases (RR 1.22, 95% CI 1.07–1.40), and osteoarthritis (RR 1.16, 95% CI 1.05–1.27). No significant correlation was found with educational status or financial hardship. Conclusion: The study indicated that certain chronic conditions are linked to increased polydoctoring among multimorbid older adults in Japan. However, most of those conditions are considered to be within a scope of family medicine/general practice. Training general practitioners to manage these conditions could reduce healthcare costs and the treatment burden, indicating a direction for future healthcare policy and medical education. [ABSTRACT FROM AUTHOR]

Published
2024
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