370 results on '"Sakurai, Fuminori"'
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2. Transplacental delivery of factor IX Fc-fusion protein ameliorates bleeding phenotype of newborn hemophilia B mice
3. Small extracellular vesicles carrying reovirus, tumor antigens, interferon-β, and damage-associated molecular patterns for efficient tumor treatment
4. Development of a novel adenovirus serotype 35 vector vaccine possessing an RGD peptide in the fiber knob and the E4 orf 4, 6, and 6/7 regions of adenovirus serotype 5
5. miR-27b targets MAIP1 to mediate lipid accumulation in cultured human and mouse hepatic cells
6. Pre-treatment of oncolytic reovirus improves tumor accumulation and intratumoral distribution of PEG-liposomes
7. Effects of pre-existing anti-adenovirus antibodies on transgene expression levels and therapeutic efficacies of arming oncolytic adenovirus
8. Preoperative CT volumetry of estimated residual kidney for prediction of postoperative chronic kidney disease in patients with renal cell carcinoma
9. miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells
10. Efficient generation of adenovirus vectors carrying the Clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR associated proteins (Cas)12a system by suppressing Cas12a expression in packaging cells
11. Enrichment of high-functioning human iPS cell-derived hepatocyte-like cells for pharmaceutical research
12. Hepatitis C virus-induced innate immune responses in human iPS cell-derived hepatocyte-like cells
13. Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling
14. Overexpression of lysophospholipid acyltransferase, LPLAT10/LPCAT4/LPEAT2, in the mouse liver increases glucose‐stimulated insulin secretion.
15. miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers
16. FGF signal is not required for hepatoblast differentiation of human iPS cells
17. Novel conditionally replicating adenovirus-mediated efficient detection of circulating tumor cells in lung cancer patients.
18. Hepatocyte Nuclear Factor 4 Alpha Promotes Definitive Endoderm Differentiation from Human Induced Pluripotent Stem Cells
19. Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes
20. Development of Mice Exhibiting Hepatic Microsomal Activity of Human CYP3A4 Comparable to That in Human Liver Microsomes by Intravenous Administration of an Adenovirus Vector Expressing Human CYP3A4
21. Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration
22. A targeted adenovirus vector displaying a human fibronectin type III domain-based monobody in a fiber protein
23. 3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing
24. The promotion of hepatic maturation of human pluripotent stem cells in 3D co-culture using type I collagen and Swiss 3T3 cell sheets
25. A hexon-specific PEGylated adenovirus vector utilizing blood coagulation factor X
26. Induction of type I interferon by adenovirus-encoded small RNAs
27. Enhanced in vivo gene transfer into the placenta using RGD fiber-mutant adenovirus vector
28. Hexon-specific PEGylated adenovirus vectors utilizing avidin-biotin interaction
29. Development of an adenovirus vector lacking the expression of virus-associated RNAs
30. An effective gene-knockdown using multiple shRNA-expressing adenovirus vectors
31. Optimization of a microRNA expression vector for function analysis of microRNA
32. Development of a recombinant adenovirus vector production system free of replication-competent adenovirus by utilizing a packaging size limit of the viral genome
33. Enhanced transduction efficiency of fiber-substituted adenovirus vectors by the incorporation of RGD peptides in two distinct regions of the adenovirus serotype 35 fiber knob
34. TANK-binding kinase 1-dependent or -independent signaling elicits the cell-type-specific innate immune responses induced by the adenovirus vector
35. Adenovirus serotype 35 vector-induced innate immune responses in dendritic cells derived from wild-type and human CD46-transgenic mice: Comparison with a fiber-substituted Ad vector containing fiber proteins of Ad serotype 35
36. Prevention of hepatic ischemia–reperfusion injury by pre-administration of catalase-expressing adenovirus vectors
37. Suppressive effects of sugar-modified cationic liposome/NF-κB decoy complexes on adenovirus vector-induced innate immune responses
38. Liver-specific overexpression of lipoprotein lipase improves glucose metabolism in high-fat diet-fed mice.
39. Efficient gene delivery in human and rodent mast cells using adenovirus vectors
40. Modification of pIX or hexon based on fiberless Ad vectors is not effective for targeted Ad vectors
41. Innate immune response induced by gene delivery vectors
42. DEVELOPMENT OF AN ADENOVIRUS VECTOR LACKING THE VIRUS-ASSOCIATED RNA EXPRESSION.: OR-32.
43. Tumor‐targeted fluorescence labeling systems for cancer diagnosis and treatment.
44. Comparison of gene expression efficiency and innate immune response induced by Ad vector and lipoplex
45. Effective tumor targeted gene transfer using PEGylated adenovirus vector via systemic administration
46. Efficient gene transfer into murine pancreatic islets using adenovirus vectors
47. Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-β gene and poly I: poly C in a murine lung metastasis model
48. ZFAND3 Overexpression in the Mouse Liver Improves Glucose Tolerance and Hepatic Insulin Resistance.
49. The short consensus repeats 1 and 2, not the cytoplasmic domain, of human CD46 are crucial for infection of subgroup B adenovirus serotype 35
50. Approaches to improving the kinetics of adenovirus-delivered genes and gene products
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