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There are a few studies on diseases of anteaters, but reports on reproductive lesions and neoplasms of these animals are scarce. This is the first report of a case of metastatic Sertoli cell tumour in a giant anteater (Myrmecophaga tridactyla). The animal had renal lesions associated with impaired renal function as indicated by serum biochemistry. Histopathological and immunohistochemical examinations provided a conclusive diagnosis of Sertoli cell tumour with metastasis to the liver, kidneys and lymph nodes. [ABSTRACT FROM AUTHOR]

Abstract: Carrageenans are galactans known in the food industry as jellifying agents. Polysaccharides from Amansia multifida were previously extracted and precipitated at different volumes of acetone, obtaining three fractions (F1, F2 and FT). Chemical and spectroscopic analysis showed that the fractions were predominantly sulfated galactans. In anticoagulant activity tests FT showed greatest activity in the aPTT test with 200μg (more than 240s). Hemolytic activity showed that FT obtained the best lysis activity of the complement system, increasing by 42.3% at 50μg. Of the three fractions analyzed, FT had the best output and anticoagulant and hemolytic effect, and was therefore chosen for in vivo inflammation assays. Inflammation tests with FT (50mg/kg) to induce cell migration and IL-6 production showed an increase of 670.1% and 531.8%, respectively. Such data confirm its use as an inducer of inflammation in experimental animal models. FT exhibited antiangiogenic action with a score of 0.95 (100μg/egg) and 1.45 (1000μg/egg). The cytotoxicity assay showed cytotoxic action in all the fractions with 48h exposure in a healthy 3T3 cell line and Hela tumor cell line, except fractions F1 and FT with 100μg. This result leads us to questions their use as food, cosmetic and drug additives. [Copyright &y& Elsevier]